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Gene editing and CRISPR in the clinic: current and future perspectives.

Hirakawa MP, Krishnakumar R, Timlin JA, Carney JP, Butler KS.

Biosci Rep. 2020 Mar 24. pii: BSR20200127. doi: 10.1042/BSR20200127. [Epub ahead of print]


New candidates for regulated gene integrity revealed through precise mapping of integrative genetic elements.

Mageeney CM, Lau BY, Wagner JM, Hudson CM, Schoeniger JS, Krishnakumar R, Williams KP.

Nucleic Acids Res. 2020 Mar 17. pii: gkaa156. doi: 10.1093/nar/gkaa156. [Epub ahead of print]


Publisher Correction: Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria.

Edwards HS, Krishnakumar R, Sinha A, Bird SW, Patel KD, Bartsch MS.

Sci Rep. 2019 Nov 20;9(1):17504. doi: 10.1038/s41598-019-53739-5.


Crystal structure and mol-ecular Hirshfeld surface analysis of acenaphthene derivatives obeying the chlorine-methyl exchange rule.

Sribala R, Indhumathi S, Krishnakumar RV, Srinivasan N.

Acta Crystallogr E Crystallogr Commun. 2019 Sep 12;75(Pt 10):1456-1462. doi: 10.1107/S2056989019012428. eCollection 2019 Oct 1.


A Method and an Experimental Setup for Measuring the Self-Noise of Piezoelectric Hydrophones.

Krishnakumar R, Ramesh R.

IEEE Trans Ultrason Ferroelectr Freq Control. 2020 Feb;67(2):413-421. doi: 10.1109/TUFFC.2019.2943955. Epub 2019 Sep 26.


Real-Time Selective Sequencing with RUBRIC: Read Until with Basecall and Reference-Informed Criteria.

Edwards HS, Krishnakumar R, Sinha A, Bird SW, Patel KD, Bartsch MS.

Sci Rep. 2019 Aug 7;9(1):11475. doi: 10.1038/s41598-019-47857-3. Erratum in: Sci Rep. 2019 Nov 20;9(1):17504.


Interleukin-6 Receptor (IL-6R) Expression in Human Gastric Carcinoma and its Clinical Significance.

Simondurairaj C, Krishnakumar R, Sundaram S, Venkatraman G.

Cancer Invest. 2019;37(7):293-298. doi: 10.1080/07357907.2019.1638395. Epub 2019 Jul 22.


Inhibitory effect of a resin coat-containing prereacted glass fillers on the enamel demineralization of the primary teeth: An in vitro pilot study.

Rabiabasree R, Krishnakumar R, Prabhu AS, Naik NS, Shashibhushan KK, Janarthanan K.

J Indian Soc Pedod Prev Dent. 2019 Apr-Jun;37(2):146-150. doi: 10.4103/JISPPD.JISPPD_309_18.


Decision Fusion-Based Fetal Ultrasound Image Plane Classification Using Convolutional Neural Networks.

Sridar P, Kumar A, Quinton A, Nanan R, Kim J, Krishnakumar R.

Ultrasound Med Biol. 2019 May;45(5):1259-1273. doi: 10.1016/j.ultrasmedbio.2018.11.016. Epub 2019 Feb 27.


Extraction and biomolecular analysis of dermal interstitial fluid collected with hollow microneedles.

Miller PR, Taylor RM, Tran BQ, Boyd G, Glaros T, Chavez VH, Krishnakumar R, Sinha A, Poorey K, Williams KP, Branda SS, Baca JT, Polsky R.

Commun Biol. 2018 Oct 22;1:173. doi: 10.1038/s42003-018-0170-z. eCollection 2018.


Isomorphous diethyl 1-(4-chloro-benz-yl)-4-(4-chloro-phen-yl)-2,2-dioxo-3,4,6,7,8,8a-hexa-hydro-1H-pyrrolo-[2,1-c][1,4]thia-zine-1,3-di-carboxyl-ate and its 1-(4-methyl-benz-yl)-4-(4-methyl-phen-yl)-substituted analogue obeying the chloro-methyl exchange rule.

Sribala R, Srinivasan N, Indumathi S, Krishnakumar RV.

Acta Crystallogr E Crystallogr Commun. 2018 Aug 16;74(Pt 9):1267-1271. doi: 10.1107/S2056989018011416. eCollection 2018 Sep 1.


Pregnancy through Assisted Reproductive Technology in a Patient with Thoracic Endometriosis Syndrome.

Krishnakumar S, Krishnakumar R, Hiwale S.

J Hum Reprod Sci. 2018 Apr-Jun;11(2):198-201. doi: 10.4103/jhrs.JHRS_133_17.


FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity.

Krishnakumar R, Chen AF, Pantovich MG, Danial M, Parchem RJ, Labosky PA, Blelloch R.

Cell Stem Cell. 2018 Aug 2;23(2):306-307. doi: 10.1016/j.stem.2018.07.015. No abstract available.


GRHL2-Dependent Enhancer Switching Maintains a Pluripotent Stem Cell Transcriptional Subnetwork after Exit from Naive Pluripotency.

Chen AF, Liu AJ, Krishnakumar R, Freimer JW, DeVeale B, Blelloch R.

Cell Stem Cell. 2018 Aug 2;23(2):226-238.e4. doi: 10.1016/j.stem.2018.06.005. Epub 2018 Jul 12.


Multidrug resistant pathogens respond differently to the presence of co-pathogen, commensal, probiotic and host cells.

Chan AP, Choi Y, Brinkac LM, Krishnakumar R, DePew J, Kim M, Hinkle MK, Lesho EP, Fouts DE.

Sci Rep. 2018 Jun 5;8(1):8656. doi: 10.1038/s41598-018-26738-1.


An unusual cause of combined cauda equina and conus medullaris syndrome.

Sajeev S, Krishnakumar R.

Neurol India. 2018 May-Jun;66(3):886-888. doi: 10.4103/0028-3886.232280. No abstract available.


Over-expression of 3-hydroxy-3- methylglutaryl-coenzyme A reductase 1 (hmgr1) gene under super-promoter for enhanced latex biosynthesis in rubber tree (Hevea brasiliensis Muell. Arg.).

Jayashree R, Nazeem PA, Rekha K, Sreelatha S, Thulaseedharan A, Krishnakumar R, Kala RG, Vineetha M, Leda P, Jinu U, Venkatachalam P.

Plant Physiol Biochem. 2018 Jun;127:414-424. doi: 10.1016/j.plaphy.2018.04.011. Epub 2018 Apr 13.


Systematic and stochastic influences on the performance of the MinION nanopore sequencer across a range of nucleotide bias.

Krishnakumar R, Sinha A, Bird SW, Jayamohan H, Edwards HS, Schoeniger JS, Patel KD, Branda SS, Bartsch MS.

Sci Rep. 2018 Feb 16;8(1):3159. doi: 10.1038/s41598-018-21484-w.


Expression of Alternative Ago2 Isoform Associated with Loss of microRNA-Driven Translational Repression in Mouse Oocytes.

Freimer JW, Krishnakumar R, Cook MS, Blelloch R.

Curr Biol. 2018 Jan 22;28(2):296-302.e3. doi: 10.1016/j.cub.2017.11.067. Epub 2018 Jan 4.


Effect of Enamel Deproteinization in Primary Teeth.

Christopher A, Krishnakumar R, Reddy NV, Rohini G.

J Clin Pediatr Dent. 2018;42(1):45-49. doi: 10.17796/1053-4628-42.1.8. Epub 2017 Sep 22.


A Comparative Evaluation of the Influence of Command Set Methods on Microleakage of Glass Ionomer Cement: An In Vitro Study.

Punnathara S, Krishnakumar R, Govindarajan M, Kanaran M, Philip ST, Nair AS, Peter J.

J Clin Diagn Res. 2017 Jun;11(6):ZC12-ZC15. doi: 10.7860/JCDR/2017/25830.9993. Epub 2017 Jun 1.


Visual functions of workers exposed to organic solvents in petrochemical industries.

Indhushree R, Monica R, Coral K, Angayarkanni N, Punitham R, Subburathinam BM, Krishnakumar R, Santanam PP.

Indian J Occup Environ Med. 2016 Sep-Dec;20(3):133-137. doi: 10.4103/0019-5278.203138.


Bell Correlations in Spin-Squeezed States of 500 000 Atoms.

Engelsen NJ, Krishnakumar R, Hosten O, Kasevich MA.

Phys Rev Lett. 2017 Apr 7;118(14):140401. doi: 10.1103/PhysRevLett.118.140401. Epub 2017 Apr 3.


Crystal structure of the cis and trans polymorphs of bis-[μ-2-(1,3-benzo-thia-zol-2-yl)phenolato]-κ3N,O:O3O:N,O-bis-[fac-tri-carbonyl-rhenium(I)].

Priyatharsini M, Shankar B, Sathiyendiran M, Srinivasan N, Krishnakumar RV.

Acta Crystallogr E Crystallogr Commun. 2017 Jan 31;73(Pt 2):310-313. doi: 10.1107/S2056989017001347. eCollection 2017 Feb 1.


Radiological and Histopathological Outcome of Giant Cell Tumor of Femur with Denosumab Treatment: A Case Report.

Menon PD, Krishnakumar R, Jojo A.

J Clin Diagn Res. 2016 Dec;10(12):RD01-RD03. doi: 10.7860/JCDR/2016/22172.9070. Epub 2016 Dec 1.


Multimodal intraoperative neuromonitoring in scoliosis surgery: A two-year prospective analysis in a single centre.

Krishnakumar R, Srivatsa N.

Neurol India. 2017 Jan-Feb;65(1):75-79. doi: 10.4103/0028-3886.198189.


Tunable Azacrown-Embedded Graphene Nanomeshes for Ion Sensing and Separation.

Krishnakumar R, Swathi RS.

ACS Appl Mater Interfaces. 2017 Jan 11;9(1):999-1010. doi: 10.1021/acsami.6b10528. Epub 2016 Dec 20.


Spinal compression fractures due to pregnancy-associated osteoporosis.

Krishnakumar R, Kumar AT, Kuzhimattam MJ.

J Craniovertebr Junction Spine. 2016 Oct-Dec;7(4):224-227.


Quantum phase magnification.

Hosten O, Krishnakumar R, Engelsen NJ, Kasevich MA.

Science. 2016 Jun 24;352(6293):1552-5. doi: 10.1126/science.aaf3397.


Measurement noise 100 times lower than the quantum-projection limit using entangled atoms.

Hosten O, Engelsen NJ, Krishnakumar R, Kasevich MA.

Nature. 2016 Jan 28;529(7587):505-8. doi: 10.1038/nature16176. Epub 2016 Jan 11.


FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity.

Krishnakumar R, Chen AF, Pantovich MG, Danial M, Parchem RJ, Labosky PA, Blelloch R.

Cell Stem Cell. 2016 Jan 7;18(1):104-17. doi: 10.1016/j.stem.2015.10.003. Erratum in: Cell Stem Cell. 2018 Aug 02;23(2):306-307.


Ogilvie's syndrome following posterior spinal instrumentation in thoraco lumbar trauma.

Krishnakumar R, Kuzhimattam MJ, Kumar G.

J Craniovertebr Junction Spine. 2015 Oct-Dec;6(4):179-82. doi: 10.4103/0974-8237.167866.


Crystal structure of 2-hy-droxy-2-(2-oxo-cyclo-hept-yl)-2,3-di-hydro-1H-indene-1,3-dione.

Ahamed PK, Srinivasan N, Ranjith Kumar R, Krishnakumar RV.

Acta Crystallogr E Crystallogr Commun. 2015 Sep 12;71(Pt 10):o715-6. doi: 10.1107/S2056989015016126. eCollection 2015 Oct 1.


Redetermined crystal structure of N-(β-carb-oxy-eth-yl)-α-isoleucine.

Chandrarekha M, Srinivasan N, Krishnakumar RV.

Acta Crystallogr E Crystallogr Commun. 2015 Aug 22;71(Pt 9):o665-6. doi: 10.1107/S2056989015014498. eCollection 2015 Sep 1.


Crystal structure of 5-benzoyl-2,4-di-phenyl-4,5-di-hydro-furan-3-carbo-nitrile.

Rajni Swamy V, Krishnakumar RV, Sivakumar S, Srinivasan N, Ranjith Kumar R.

Acta Crystallogr E Crystallogr Commun. 2015 Aug 15;71(Pt 9):o663-4. doi: 10.1107/S2056989015014887. eCollection 2015 Sep 1.


Effect of the Raga Ananda Bhairavi in Post Operative Pain Relief Management.

Kumar TS, Muthuraman M, Krishnakumar R.

Indian J Surg. 2014 Oct;76(5):363-70. doi: 10.1007/s12262-012-0705-3. Epub 2012 Aug 1.


Naked facet sign in a case of traumatic injury to the thoracic vertebra.

Kuzhimattam MJ, Krishnakumar R.

Spine J. 2016 Feb;16(2):e37-8. doi: 10.1016/j.spinee.2015.09.023. Epub 2015 Sep 24. No abstract available.


A novel method of consensus pan-chromosome assembly and large-scale comparative analysis reveal the highly flexible pan-genome of Acinetobacter baumannii.

Chan AP, Sutton G, DePew J, Krishnakumar R, Choi Y, Huang XZ, Beck E, Harkins DM, Kim M, Lesho EP, Nikolich MP, Fouts DE.

Genome Biol. 2015 Jul 21;16:143. doi: 10.1186/s13059-015-0701-6.


Isolated bilateral mandibular angle fractures: an extensive literature review of the rare clinical phenomenon with presentation of a classical clinical model.

Elavenil P, Mohanavalli S, Sasikala B, Prasanna RA, Krishnakumar RV.

Craniomaxillofac Trauma Reconstr. 2015 Jun;8(2):153-8. doi: 10.1055/s-0034-1393738. Epub 2014 Nov 24.


Incontinentia pigmenti: a rare genodermatosis in a male child.

Swamy DK, Arunagirinathan A, Krishnakumar R, Sangili S.

J Clin Diagn Res. 2015 Feb;9(2):SD06-8. doi: 10.7860/JCDR/2015/12171.5561. Epub 2015 Feb 1.


Phase II study of interim PET-CT-guided response-adapted therapy in advanced Hodgkin's lymphoma.

Ganesan P, Rajendranath R, Kannan K, Radhakrishnan V, Ganesan TS, Udupa K, Lakshmipathy KM, Mahajan V, Sundersingh S, Rajaraman S, Krishnakumar R, Sagar TG.

Ann Oncol. 2015 Jun;26(6):1170-4. doi: 10.1093/annonc/mdv077. Epub 2015 Feb 20.


Crystal structure of 4-sulfamoylanilinium di-hydrogen phosphate.

Muthuselvi C, Mala N, Srinivasan N, Pandiarajan S, Krishnakumar RV.

Acta Crystallogr Sect E Struct Rep Online. 2014 Aug 13;70(Pt 9):o997-8. doi: 10.1107/S1600536814017462. eCollection 2014 Sep 1.


Crystal structure of [4-(2-meth-oxy-phen-yl)-3-methyl-1-phenyl-6-tri-fluoro-methyl-1H-pyrazolo-[3,4-b]pyridin-5-yl](thio-phen-2-yl)methanone.

Rajni Swamy V, Gunasekaran P, Krishnakumar RV, Srinivasan N, Müller P.

Acta Crystallogr Sect E Struct Rep Online. 2014 Aug 6;70(Pt 9):o974-5. doi: 10.1107/S1600536814017437. eCollection 2014 Sep 1.


HIV/AIDS knowledge and its implications on dentists.

Prabhu A, Rao AP, Reddy V, Krishnakumar R, Thayumanavan S, Swathi SS.

J Nat Sci Biol Med. 2014 Jul;5(2):303-7. doi: 10.4103/0976-9668.136171.


Answer to the topic "management of pyogenic discitis".

Devkota P, Krishnakumar R, Renjith Kumar J.

Asian Spine J. 2014 Jun;8(3):392. doi: 10.4184/asj.2014.8.3.392. Epub 2014 Jun 9. No abstract available.


Simultaneous non-contiguous deletions using large synthetic DNA and site-specific recombinases.

Krishnakumar R, Grose C, Haft DH, Zaveri J, Alperovich N, Gibson DG, Merryman C, Glass JI.

Nucleic Acids Res. 2014 Aug;42(14):e111. doi: 10.1093/nar/gku509. Epub 2014 Jun 9.


Surgical management of pyogenic discitis of lumbar region.

Devkota P, Krishnakumar R, Renjith Kumar J.

Asian Spine J. 2014 Apr;8(2):177-82. doi: 10.4184/asj.2014.8.2.177. Epub 2014 Apr 8.


Two miRNA clusters reveal alternative paths in late-stage reprogramming.

Parchem RJ, Ye J, Judson RL, LaRussa MF, Krishnakumar R, Blelloch A, Oldham MC, Blelloch R.

Cell Stem Cell. 2014 May 1;14(5):617-31. doi: 10.1016/j.stem.2014.01.021. Epub 2014 Mar 13.

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