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Items: 1 to 50 of 125

1.

The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance.

Cooke A, Schwarzl T, Huppertz I, Kramer G, Mantas P, Alleaume AM, Huber W, Krijgsveld J, Hentze MW.

Cell Rep. 2019 Jun 11;27(11):3097-3106.e5. doi: 10.1016/j.celrep.2019.05.039.

2.

EZHIP / CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma.

Hübner JM, Müller T, Papageorgiou DN, Mauermann M, Krijgsveld J, Russell RB, Ellison DW, Pfister SM, Pajtler KW, Kool M.

Neuro Oncol. 2019 Mar 29. pii: noz058. doi: 10.1093/neuonc/noz058. [Epub ahead of print]

PMID:
30923826
3.

Secretome profiling of heterotypic spheroids suggests a role of fibroblasts in HIF-1 pathway modulation and colorectal cancer photodynamic resistance.

Lamberti MJ, Rettel M, Krijgsveld J, Rivarola VA, Rumie Vittar NB.

Cell Oncol (Dordr). 2019 Apr;42(2):173-196. doi: 10.1007/s13402-018-00418-8. Epub 2019 Feb 12.

PMID:
30756254
4.

Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling.

Bossler F, Kuhn BJ, Günther T, Kraemer SJ, Khalkar P, Adrian S, Lohrey C, Holzer A, Shimobayashi M, Dürst M, Mayer A, Rösl F, Grundhoff A, Krijgsveld J, Hoppe-Seyler K, Hoppe-Seyler F.

MBio. 2019 Feb 12;10(1). pii: e02323-18. doi: 10.1128/mBio.02323-18.

5.

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring.

Cagnetta R, Wong HH, Frese CK, Mallucci GR, Krijgsveld J, Holt CE.

Mol Cell. 2019 Feb 7;73(3):474-489.e5. doi: 10.1016/j.molcel.2018.11.013. Epub 2018 Dec 27.

6.

The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest.

Trendel J, Schwarzl T, Horos R, Prakash A, Bateman A, Hentze MW, Krijgsveld J.

Cell. 2019 Jan 10;176(1-2):391-403.e19. doi: 10.1016/j.cell.2018.11.004. Epub 2018 Dec 6.

PMID:
30528433
7.

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments.

Hughes CS, Moggridge S, Müller T, Sorensen PH, Morin GB, Krijgsveld J.

Nat Protoc. 2019 Jan;14(1):68-85. doi: 10.1038/s41596-018-0082-x.

PMID:
30464214
8.

The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ.

Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, Aragona M, Giulitti S, Panciera T, Gandin A, Sigismondo G, Krijgsveld J, Fassan M, Brusatin G, Cordenonsi M, Piccolo S.

Nature. 2018 Nov;563(7730):265-269. doi: 10.1038/s41586-018-0658-1. Epub 2018 Oct 31.

PMID:
30401838
9.

Spatial Distribution of Endogenous Tissue Protease Activity in Gastric Carcinoma Mapped by MALDI Mass Spectrometry Imaging.

Erich K, Reinle K, Müller T, Munteanu B, Sammour DA, Hinsenkamp I, Gutting T, Burgermeister E, Findeisen P, Ebert MP, Krijgsveld J, Hopf C.

Mol Cell Proteomics. 2019 Jan;18(1):151-161. doi: 10.1074/mcp.RA118.000980. Epub 2018 Oct 7.

PMID:
30293968
10.

Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4.

Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, Quaranta E, Di Biagio D, Sigismondo G, Guzzardo V, Lejeune P, Haendler B, Krijgsveld J, Fassan M, Bicciato S, Cordenonsi M, Piccolo S.

Nat Med. 2018 Oct;24(10):1599-1610. doi: 10.1038/s41591-018-0158-8. Epub 2018 Sep 17.

11.

Comparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel Adipokines.

Ali Khan A, Hansson J, Weber P, Foehr S, Krijgsveld J, Herzig S, Scheideler M.

Mol Cell Proteomics. 2018 Dec;17(12):2358-2370. doi: 10.1074/mcp.RA118.000704. Epub 2018 Aug 22.

PMID:
30135203
12.

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.

Raffel S, Falcone M, Kneisel N, Hansson J, Wang W, Lutz C, Bullinger L, Poschet G, Nonnenmacher Y, Barnert A, Bahr C, Zeisberger P, Przybylla A, Sohn M, Tönjes M, Erez A, Adler L, Jensen P, Scholl C, Fröhling S, Cocciardi S, Wuchter P, Thiede C, Flörcken A, Westermann J, Ehninger G, Lichter P, Hiller K, Hell R, Herrmann C, Ho AD, Krijgsveld J, Radlwimmer B, Trumpp A.

Nature. 2018 Aug;560(7718):E28. doi: 10.1038/s41586-018-0403-9.

PMID:
30069041
13.

Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome.

Cagnetta R, Frese CK, Shigeoka T, Krijgsveld J, Holt CE.

Neuron. 2018 Jul 11;99(1):29-46.e4. doi: 10.1016/j.neuron.2018.06.004. Epub 2018 Jun 28.

14.

An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein.

Dewari PS, Southgate B, Mccarten K, Monogarov G, O'Duibhir E, Quinn N, Tyrer A, Leitner MC, Plumb C, Kalantzaki M, Blin C, Finch R, Bressan RB, Morrison G, Jacobi AM, Behlke MA, von Kriegsheim A, Tomlinson S, Krijgsveld J, Pollard SM.

Elife. 2018 Apr 11;7. pii: e35069. doi: 10.7554/eLife.35069.

15.

Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC).

Buczak K, Ori A, Kirkpatrick JM, Holzer K, Dauch D, Roessler S, Endris V, Lasitschka F, Parca L, Schmidt A, Zender L, Schirmacher P, Krijgsveld J, Singer S, Beck M.

Mol Cell Proteomics. 2018 Apr;17(4):810-825. doi: 10.1074/mcp.RA117.000189. Epub 2018 Jan 23.

16.

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.

Raffel S, Falcone M, Kneisel N, Hansson J, Wang W, Lutz C, Bullinger L, Poschet G, Nonnenmacher Y, Barnert A, Bahr C, Zeisberger P, Przybylla A, Sohn M, Tönjes M, Erez A, Adler L, Jensen P, Scholl C, Fröhling S, Cocciardi S, Wuchter P, Thiede C, Flörcken A, Westermann J, Ehninger G, Lichter P, Hiller K, Hell R, Herrmann C, Ho AD, Krijgsveld J, Radlwimmer B, Trumpp A.

Nature. 2017 Nov 16;551(7680):384-388. doi: 10.1038/nature24294. Epub 2017 Nov 8. Erratum in: Nature. 2018 Aug;560(7718):E28.

PMID:
29144447
17.

Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap.

Castello A, Frese CK, Fischer B, Järvelin AI, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW.

Nat Protoc. 2017 Dec;12(12):2447-2464. doi: 10.1038/nprot.2017.106. Epub 2017 Nov 2.

PMID:
29095441
18.

Advances in stem cell proteomics.

Abazova N, Krijgsveld J.

Curr Opin Genet Dev. 2017 Oct;46:149-155. doi: 10.1016/j.gde.2017.07.007. Epub 2017 Aug 11. Review.

PMID:
28806595
19.

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells.

Nötzold L, Frank L, Gandhi M, Polycarpou-Schwarz M, Groß M, Gunkel M, Beil N, Erfle H, Harder N, Rohr K, Trendel J, Krijgsveld J, Longerich T, Schirmacher P, Boutros M, Erhardt S, Diederichs S.

Sci Rep. 2017 May 23;7(1):2265. doi: 10.1038/s41598-017-02357-0.

20.

Specific RNP capture with antisense LNA/DNA mixmers.

Rogell B, Fischer B, Rettel M, Krijgsveld J, Castello A, Hentze MW.

RNA. 2017 Aug;23(8):1290-1302. doi: 10.1261/rna.060798.117. Epub 2017 May 5.

21.

Proteome and Secretome Characterization of Glioblastoma-Derived Neural Stem Cells.

Okawa S, Gagrica S, Blin C, Ender C, Pollard SM, Krijgsveld J.

Stem Cells. 2017 Apr;35(4):967-980. doi: 10.1002/stem.2542. Epub 2016 Dec 4.

22.

Turning Over Paradigms in Protein Decay.

Kramer G, Krijgsveld J.

Dev Cell. 2016 Nov 7;39(3):284-285. doi: 10.1016/j.devcel.2016.10.018.

23.

Expanding the Circuitry of Pluripotency by Selective Isolation of Chromatin-Associated Proteins.

Rafiee MR, Girardot C, Sigismondo G, Krijgsveld J.

Mol Cell. 2016 Nov 3;64(3):624-635. doi: 10.1016/j.molcel.2016.09.019. Epub 2016 Oct 20.

24.

Comprehensive Identification of RNA-Binding Domains in Human Cells.

Castello A, Fischer B, Frese CK, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW.

Mol Cell. 2016 Aug 18;63(4):696-710. doi: 10.1016/j.molcel.2016.06.029. Epub 2016 Jul 21.

25.

The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease.

Liao Y, Castello A, Fischer B, Leicht S, Föehr S, Frese CK, Ragan C, Kurscheid S, Pagler E, Yang H, Krijgsveld J, Hentze MW, Preiss T.

Cell Rep. 2016 Aug 2;16(5):1456-1469. doi: 10.1016/j.celrep.2016.06.084. Epub 2016 Jul 21.

26.

Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila.

Sysoev VO, Fischer B, Frese CK, Gupta I, Krijgsveld J, Hentze MW, Castello A, Ephrussi A.

Nat Commun. 2016 Jul 5;7:12128. doi: 10.1038/ncomms12128.

27.

Identification of RNA-binding Proteins in Macrophages by Interactome Capture.

Liepelt A, Naarmann-de Vries IS, Simons N, Eichelbaum K, Föhr S, Archer SK, Castello A, Usadel B, Krijgsveld J, Preiss T, Marx G, Hentze MW, Ostareck DH, Ostareck-Lederer A.

Mol Cell Proteomics. 2016 Aug;15(8):2699-714. doi: 10.1074/mcp.M115.056564. Epub 2016 Jun 8.

28.

Identification of Maturation-Specific Proteins by Single-Cell Proteomics of Human Oocytes.

Virant-Klun I, Leicht S, Hughes C, Krijgsveld J.

Mol Cell Proteomics. 2016 Aug;15(8):2616-27. doi: 10.1074/mcp.M115.056887. Epub 2016 May 23.

29.

Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.

Schäfer M, Oeing CU, Rohm M, Baysal-Temel E, Lehmann LH, Bauer R, Volz HC, Boutros M, Sohn D, Sticht C, Gretz N, Eichelbaum K, Werner T, Hirt MN, Eschenhagen T, Müller-Decker K, Strobel O, Hackert T, Krijgsveld J, Katus HA, Berriel Diaz M, Backs J, Herzig S.

Mol Metab. 2015 Nov 26;5(2):67-78. doi: 10.1016/j.molmet.2015.11.004. eCollection 2016 Feb.

30.

Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay.

Sieber J, Hauer C, Bhuvanagiri M, Leicht S, Krijgsveld J, Neu-Yilik G, Hentze MW, Kulozik AE.

Mol Cell Proteomics. 2016 May;15(5):1584-97. doi: 10.1074/mcp.M115.054056. Epub 2016 Feb 20.

31.

Activation of the TGFβ pathway impairs endothelial to haematopoietic transition.

Vargel Ö, Zhang Y, Kosim K, Ganter K, Foehr S, Mardenborough Y, Shvartsman M, Enright AJ, Krijgsveld J, Lancrin C.

Sci Rep. 2016 Feb 19;6:21518. doi: 10.1038/srep21518.

32.

Crystal Structure of the CTP1L Endolysin Reveals How Its Activity Is Regulated by a Secondary Translation Product.

Dunne M, Leicht S, Krichel B, Mertens HD, Thompson A, Krijgsveld J, Svergun DI, Gómez-Torres N, Garde S, Uetrecht C, Narbad A, Mayer MJ, Meijers R.

J Biol Chem. 2016 Mar 4;291(10):4882-93. doi: 10.1074/jbc.M115.671172. Epub 2015 Dec 18.

33.

The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs.

Beckmann BM, Horos R, Fischer B, Castello A, Eichelbaum K, Alleaume AM, Schwarzl T, Curk T, Foehr S, Huber W, Krijgsveld J, Hentze MW.

Nat Commun. 2015 Dec 3;6:10127. doi: 10.1038/ncomms10127.

34.

Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions.

Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C.

ACS Chem Biol. 2016 Jan 15;11(1):222-30. doi: 10.1021/acschembio.5b00810. Epub 2015 Nov 25.

PMID:
26555438
35.

Comprehensive Identification of RNA-Binding Proteins by RNA Interactome Capture.

Castello A, Horos R, Strein C, Fischer B, Eichelbaum K, Steinmetz LM, Krijgsveld J, Hentze MW.

Methods Mol Biol. 2016;1358:131-9. doi: 10.1007/978-1-4939-3067-8_8.

PMID:
26463381
36.

Transcription Factor 7 Limits Regulatory T Cell Generation in the Thymus.

Barra MM, Richards DM, Hansson J, Hofer AC, Delacher M, Hettinger J, Krijgsveld J, Feuerer M.

J Immunol. 2015 Oct 1;195(7):3058-70. doi: 10.4049/jimmunol.1500821. Epub 2015 Aug 31.

37.

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors.

Haas S, Hansson J, Klimmeck D, Loeffler D, Velten L, Uckelmann H, Wurzer S, Prendergast ÁM, Schnell A, Hexel K, Santarella-Mellwig R, Blaszkiewicz S, Kuck A, Geiger H, Milsom MD, Steinmetz LM, Schroeder T, Trumpp A, Krijgsveld J, Essers MA.

Cell Stem Cell. 2015 Oct 1;17(4):422-34. doi: 10.1016/j.stem.2015.07.007. Epub 2015 Aug 20.

38.

Transcriptome-wide profiling and posttranscriptional analysis of hematopoietic stem/progenitor cell differentiation toward myeloid commitment.

Klimmeck D, Cabezas-Wallscheid N, Reyes A, von Paleske L, Renders S, Hansson J, Krijgsveld J, Huber W, Trumpp A.

Stem Cell Reports. 2014 Nov 11;3(5):858-75. doi: 10.1016/j.stemcr.2014.08.012. Epub 2014 Sep 25.

39.

Ultrasensitive proteome analysis using paramagnetic bead technology.

Hughes CS, Foehr S, Garfield DA, Furlong EE, Steinmetz LM, Krijgsveld J.

Mol Syst Biol. 2014 Oct 30;10:757. doi: 10.15252/msb.20145625.

40.

Quantitative proteomics reveals the dynamics of protein changes during Drosophila oocyte maturation and the oocyte-to-embryo transition.

Kronja I, Whitfield ZJ, Yuan B, Dzeyk K, Kirkpatrick J, Krijgsveld J, Orr-Weaver TL.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16023-8. doi: 10.1073/pnas.1418657111. Epub 2014 Oct 27.

41.

5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.

Bhuvanagiri M, Lewis J, Putzker K, Becker JP, Leicht S, Krijgsveld J, Batra R, Turnwald B, Jovanovic B, Hauer C, Sieber J, Hentze MW, Kulozik AE.

EMBO Mol Med. 2014 Dec;6(12):1593-609. doi: 10.15252/emmm.201404461.

42.

Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.

Cabezas-Wallscheid N, Klimmeck D, Hansson J, Lipka DB, Reyes A, Wang Q, Weichenhan D, Lier A, von Paleske L, Renders S, Wünsche P, Zeisberger P, Brocks D, Gu L, Herrmann C, Haas S, Essers MAG, Brors B, Eils R, Huber W, Milsom MD, Plass C, Krijgsveld J, Trumpp A.

Cell Stem Cell. 2014 Oct 2;15(4):507-522. doi: 10.1016/j.stem.2014.07.005. Epub 2014 Aug 21.

43.

New advances in reproductive biomedicine.

Virant-Klun I, Krijgsveld J, Huntriss J, Rodgers RJ.

Biomed Res Int. 2014;2014:529170. doi: 10.1155/2014/529170. Epub 2014 Jun 19. No abstract available.

44.

Combining pulsed SILAC labeling and click-chemistry for quantitative secretome analysis.

Eichelbaum K, Krijgsveld J.

Methods Mol Biol. 2014;1174:101-14. doi: 10.1007/978-1-4939-0944-5_7.

PMID:
24947377
45.

Widespread changes in the posttranscriptional landscape at the Drosophila oocyte-to-embryo transition.

Kronja I, Yuan B, Eichhorn SW, Dzeyk K, Krijgsveld J, Bartel DP, Orr-Weaver TL.

Cell Rep. 2014 Jun 12;7(5):1495-1508. doi: 10.1016/j.celrep.2014.05.002. Epub 2014 May 29.

46.

Proteomes of animal oocytes: what can we learn for human oocytes in the in vitro fertilization programme?

Virant-Klun I, Krijgsveld J.

Biomed Res Int. 2014;2014:856907. doi: 10.1155/2014/856907. Epub 2014 Apr 3. Review.

47.

Suppression of Mediator is regulated by Cdk8-dependent Grr1 turnover of the Med3 coactivator.

Gonzalez D, Hamidi N, Del Sol R, Benschop JJ, Nancy T, Li C, Francis L, Tzouros M, Krijgsveld J, Holstege FC, Conlan RS.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2500-5. doi: 10.1073/pnas.1307525111. Epub 2014 Feb 3.

48.

Rapid temporal dynamics of transcription, protein synthesis, and secretion during macrophage activation.

Eichelbaum K, Krijgsveld J.

Mol Cell Proteomics. 2014 Mar;13(3):792-810. doi: 10.1074/mcp.M113.030916. Epub 2014 Jan 6.

49.

CHD4 is a RanGTP-dependent MAP that stabilizes microtubules and regulates bipolar spindle formation.

Yokoyama H, Nakos K, Santarella-Mellwig R, Rybina S, Krijgsveld J, Koffa MD, Mattaj IW.

Curr Biol. 2013 Dec 16;23(24):2443-51. doi: 10.1016/j.cub.2013.09.062. Epub 2013 Nov 21.

50.

Src kinase modulates the apoptotic p53 pathway by altering HIPK2 localization.

Polonio-Vallon T, Kirkpatrick J, Krijgsveld J, Hofmann TG.

Cell Cycle. 2014;13(1):115-25. doi: 10.4161/cc.26857. Epub 2013 Oct 25.

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