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Items: 1 to 50 of 60

1.

In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform.

Scholz EP, Alter M, Zitron E, Kiesecker C, Kathöfer S, Thomas D, Kreye VA, Kreuzer J, Becker R, Katus HA, Greten J, Karle CA.

Toxicol Lett. 2006 Aug 20;165(2):156-66. Epub 2006 Mar 27.

PMID:
16647228
2.

Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1.

Kiesecker C, Zitron E, Scherer D, Lueck S, Bloehs R, Scholz EP, Pirot M, Kathöfer S, Thomas D, Kreye VA, Kiehn J, Borst MM, Katus HA, Schoels W, Karle CA.

J Mol Med (Berl). 2006 Jan;84(1):46-56. Epub 2005 Oct 29.

PMID:
16258766
3.

Inhibition of cardiac HERG channels by grapefruit flavonoid naringenin: implications for the influence of dietary compounds on cardiac repolarisation.

Scholz EP, Zitron E, Kiesecker C, Lück S, Thomas D, Kathöfer S, Kreye VA, Katus HA, Kiehn J, Schoels W, Karle CA.

Naunyn Schmiedebergs Arch Pharmacol. 2005 Jun;371(6):516-25. Epub 2005 Jul 9.

PMID:
16007460
4.

QTc prolongation by grapefruit juice and its potential pharmacological basis: HERG channel blockade by flavonoids.

Zitron E, Scholz E, Owen RW, Lück S, Kiesecker C, Thomas D, Kathöfer S, Niroomand F, Kiehn J, Kreye VA, Katus HA, Schoels W, Karle CA.

Circulation. 2005 Feb 22;111(7):835-8. Epub 2005 Feb 14.

PMID:
15710766
5.

Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action.

Kiesecker C, Zitron E, Lück S, Bloehs R, Scholz EP, Kathöfer S, Thomas D, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Dec;370(6):423-35. Epub 2004 Oct 30.

PMID:
15599706
6.

Identification and characterisation of a novel KCNQ1 mutation in a family with Romano-Ward syndrome.

Zehelein J, Thomas D, Khalil M, Wimmer AB, Koenen M, Licka M, Wu K, Kiehn J, Brockmeier K, Kreye VA, Karle CA, Katus HA, Ulmer HE, Schoels W.

Biochim Biophys Acta. 2004 Nov 5;1690(3):185-92.

7.

Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors.

Thomas D, Wu K, Wimmer AB, Zitron E, Hammerling BC, Kathöfer S, Lueck S, Bloehs R, Kreye VA, Kiehn J, Katus HA, Schoels W, Karle CA.

J Mol Med (Berl). 2004 Dec;82(12):826-37. Epub 2004 Sep 8.

PMID:
15365637
8.

Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone.

Zitron E, Kiesecker C, Scholz E, Lück S, Bloehs R, Kathöfer S, Thomas D, Kiehn J, Kreye VA, Katus HA, Schoels W, Karle CA.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):146-56. Epub 2004 Jul 29.

PMID:
15322737
9.

Human cardiac inwardly rectifying current IKir2.2 is upregulated by activation of protein kinase A.

Zitron E, Kiesecker C, Lück S, Kathöfer S, Thomas D, Kreye VA, Kiehn J, Katus HA, Schoels W, Karle CA.

Cardiovasc Res. 2004 Aug 15;63(3):520-7.

PMID:
15276477
10.

Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action.

Thomas D, Hammerling BC, Wu K, Wimmer AB, Ficker EK, Kirsch GE, Kochan MC, Wible BA, Scholz EP, Zitron E, Kathöfer S, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J.

Br J Pharmacol. 2004 Jun;142(3):485-94. Epub 2004 May 17.

11.

Hypoxia-induced inhibition of whole cell membrane currents and ion transport of A549 cells.

Karle C, Gehrig T, Wodopia R, Höschele S, Kreye VA, Katus HA, Bärtsch P, Mairbäurl H.

Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6):L1154-60. Epub 2004 Jan 16. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2004 Oct;31(4):L890.

12.

Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.

Scholz EP, Zitron E, Kiesecker C, Lueck S, Kathöfer S, Thomas D, Weretka S, Peth S, Kreye VA, Schoels W, Katus HA, Kiehn J, Karle CA.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Nov;368(5):404-14. Epub 2003 Oct 14.

PMID:
14557918
13.

Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels.

Thomas D, Kathofer S, Zhang W, Wu K, Wimmer AB, Zitron E, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J.

Br J Pharmacol. 2003 Nov;140(5):996-1002. Epub 2003 Sep 29.

14.

Regulation of HERG potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein.

Thomas D, Zhang W, Wu K, Wimmer AB, Gut B, Wendt-Nordahl G, Kathöfer S, Kreye VA, Katus HA, Schoels W, Kiehn J, Karle CA.

Cardiovasc Res. 2003 Jul 1;59(1):14-26.

PMID:
12829172
15.

Protein kinase A-mediated phosphorylation of HERG potassium channels in a human cell line.

Wei Z, Thomas D, Karle CA, Kathöfer S, Schenkel J, Kreye VA, Ficker E, Wible BA, Kiehn J.

Chin Med J (Engl). 2002 May;115(5):668-76.

PMID:
12133532
16.

Vascular effects of class-III antiarrhythmic drugs: chromanol 293B, but not dofetilide blocks the smooth muscle delayed rectifier K+ channel.

Karle CA, Bauer A, Weretka S, Zitron E, Abushi A, Kreye VA, Schoels W.

Basic Res Cardiol. 2002 Jan;97(1):17-25.

PMID:
11998973
17.

Antiarrhythmic drug carvedilol inhibits HERG potassium channels.

Karle CA, Kreye VA, Thomas D, Röckl K, Kathöfer S, Zhang W, Kiehn J.

Cardiovasc Res. 2001 Feb 1;49(2):361-70.

PMID:
11164846
18.

A K+ single channel and whole-cell clamp study on the effects of levocromakalim in guinea pig portal vein cells.

Karle CA, Yao X, Kreye VA.

Naunyn Schmiedebergs Arch Pharmacol. 1998 Sep;358(3):374-81.

PMID:
9774226
19.

Intracellular ADP activates ATP-sensitive K+ channels in vascular smooth muscle cells of the guinea pig portal vein.

Pfründer D, Anghelescu I, Kreye VA.

Pflugers Arch. 1993 Apr;423(1-2):149-51.

PMID:
8488087
20.
22.

Pharmacological characterization of nicorandil by 86Rb efflux and isometric vasorelaxation studies in vascular smooth muscle.

Kreye VA, Lenz T, Pfründer D, Theiss U.

J Cardiovasc Pharmacol. 1992;20 Suppl 3:S8-12.

PMID:
1282181
25.
26.

Characterization of the K(+)-channel-coupled adenosine receptor in guinea pig atria.

Tawfik-Schlieper H, Klotz KN, Kreye VA, Schwabe U.

Naunyn Schmiedebergs Arch Pharmacol. 1989 Dec;340(6):684-8.

PMID:
2615858
27.
28.

A chloride-bicarbonate exchanging anion carrier in vascular smooth muscle of the rabbit.

Gerstheimer FP, Mühleisen M, Nehring D, Kreye VA.

Pflugers Arch. 1987 Jun;409(1-2):60-6.

PMID:
3615172
29.

Barium can replace calcium in calmodulin-dependent contractions of skinned renal arteries of the rabbit.

Kreye VA, Hofmann F, Mühleisen M.

Pflugers Arch. 1986 Mar;406(3):308-11.

PMID:
3960707
30.

Mode of action of nitrates at the cellular level.

Kreye VA, Hofmann F, Villhauer I.

Z Kardiol. 1986;75 Suppl 3:16-9. Review.

PMID:
3026102
31.

Lack of soluble carbonic anhydrase in aortic smooth muscle of the rabbit.

Mühleisen M, Kreye VA.

Pflugers Arch. 1985 Oct;405(3):234-6.

PMID:
3934642
32.

Inhibition of noradrenaline-stimulated 86Rb/K+-exchange in vascular smooth muscle by porcine vasorelaxant atrial peptide, cardiodilatin-88.

Kreye VA, Forssmann WG, Gerstheimer F.

Regul Pept Suppl. 1985;4:141-3. No abstract available.

PMID:
3864192
34.

Direct vasodilators with unknown modes of action: the nitro-compounds and hydralazine.

Kreye VA.

J Cardiovasc Pharmacol. 1984;6 Suppl 4:S646-55. Review.

PMID:
6083407
35.
36.

Differential effects of hydralazine on the biphasic responses of helical strips from rat tail arteries.

Khayyal M, Gross F, Kreye VA.

Gen Pharmacol. 1983;14(1):121-3. No abstract available.

PMID:
6826022
38.

Possible site of the in vivo disposition of sodium nitroprusside in the rat.

Kreye VA, Reske SN.

Naunyn Schmiedebergs Arch Pharmacol. 1982 Sep;320(3):260-5. No abstract available.

PMID:
7133156
39.

Diminished vascular response to noradrenaline in experimental chronic uremia.

Rascher W, Schömig A, Kreye VA, Ritz E.

Kidney Int. 1982 Jan;21(1):20-7. No abstract available.

40.

Vascular effects of parathyroid hormone (PTH).

Rambausek M, Ritz E, Rascher W, Kreusser W, Mann JF, Kreye VA, Mehls O.

Adv Exp Med Biol. 1982;151:619-32. Review.

PMID:
6758527
41.

Evidence for furosemide-sensitive active chloride transport in vascular smooth muscle.

Kreye VA, Bauer PK, Villhauer I.

Eur J Pharmacol. 1981 Jul 17;73(1):91-5.

PMID:
7318891
42.

Studies on the direct vasodilator effect of hydralazine in the isolated rabbit renal artery.

Khayyal M, Gross F, Kreye VA.

J Pharmacol Exp Ther. 1981 Feb;216(2):390-4.

PMID:
7463355
44.

Sodium nitroprusside: comparison of the antidotal effect of hydroxocobalamin and sodium thiosulfate in rabbits.

Pill J, Engeser P, Höbel M, Kreye VA.

Dev Toxicol Environ Sci. 1980;8:423-6. No abstract available.

PMID:
7308042
45.

Comparison of sodium nitroprusside and isoprenaline aerosols in histamine-induced bronchial asthma of the guinea pig.

Kreye VA, Marquard E.

Naunyn Schmiedebergs Arch Pharmacol. 1979 Apr;306(3):203-7.

PMID:
471074
46.

Relaxation of hormonally stimulated smooth muscular tissues by the 8-bromo derivative of cyclic GMP.

Schultz KD, Böhme E, Kreye VA, Schultz G.

Naunyn Schmiedebergs Arch Pharmacol. 1979 Jan;306(1):1-9. No abstract available.

PMID:
218117
48.

Organotoxic effects of excessive doses of sodium nitroprusside in the rabbit.

Höbel M, Kreye VA, Nemes Z, Pill J.

Klin Wochenschr. 1978;56 Suppl 1:153-9.

PMID:
32431
49.

[Vasodilating-acting antihypertensive agents: model substance sodium nitroprusside].

Kreye VA, Reske SN, Schultz KD.

Verh Dtsch Ges Kreislaufforsch. 1977;43:87-96. German. No abstract available.

PMID:
613683
50.

Proceedings: Verapamil-induced phasic contractions of the isolated rat vas deferens.

Kreye VA, Lüth JB.

Naunyn Schmiedebergs Arch Pharmacol. 1975;287 Suppl:R43. No abstract available.

PMID:
1143442

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