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Items: 1 to 50 of 138

1.

Branch site bulge conformations in domain 6 determine functional sugar puckers in group II intron splicing.

Plangger R, Juen MA, Hoernes TP, Nußbaumer F, Kremser J, Strebitzer E, Klingler D, Erharter K, Tollinger M, Erlacher MD, Kreutz C.

Nucleic Acids Res. 2019 Oct 29. pii: gkz965. doi: 10.1093/nar/gkz965. [Epub ahead of print]

PMID:
31665419
2.

Direct evidence for (G)O6···H2-N4(C)+ hydrogen bonding in transient G(syn)-C+ and G(syn)-m5C+ Hoogsteen base pairs in duplex DNA from cytosine amino nitrogen off-resonance R relaxation dispersion measurements.

Rangadurai A, Kremser J, Shi H, Kreutz C, Al-Hashimi HM.

J Magn Reson. 2019 Nov;308:106589. doi: 10.1016/j.jmr.2019.106589. Epub 2019 Sep 5.

PMID:
31539864
3.

Dynamic ensemble of HIV-1 RRE stem IIB reveals non-native conformations that disrupt the Rev-binding site.

Chu CC, Plangger R, Kreutz C, Al-Hashimi HM.

Nucleic Acids Res. 2019 Jul 26;47(13):7105-7117. doi: 10.1093/nar/gkz498.

4.

The Hydrogenobyric Acid Structure Reveals the Corrin Ligand as an Entatic State Module Empowering B12 Cofactors for Catalysis.

Kieninger C, Deery E, Lawrence AD, Podewitz M, Wurst K, Nemoto-Smith E, Widner FJ, Baker JA, Jockusch S, Kreutz CR, Liedl KR, Gruber K, Warren MJ, Kräutler B.

Angew Chem Int Ed Engl. 2019 Jul 29;58(31):10756-10760. doi: 10.1002/anie.201904713. Epub 2019 Jun 26.

5.

Access to 3-Deazaguanosine Building Blocks for RNA Solid-Phase Synthesis Involving Hartwig-Buchwald C-N Cross-Coupling.

Mairhofer E, Flemmich L, Kreutz C, Micura R.

Org Lett. 2019 Jun 7;21(11):3900-3903. doi: 10.1021/acs.orglett.9b00855. Epub 2019 May 13.

PMID:
31081638
6.

NMR resonance assignments for the GTP-binding RNA aptamer 9-12 in complex with GTP.

Wolter AC, Pianu A, Kremser J, Strebitzer E, Schnieders R, Fürtig B, Kreutz C, Duchardt-Ferner E, Wöhnert J.

Biomol NMR Assign. 2019 Oct;13(2):281-286. doi: 10.1007/s12104-019-09892-z. Epub 2019 Apr 27.

PMID:
31030336
7.

Effects of physical and mind-body exercise on sleep problems during and after breast cancer treatment: a systematic review and meta-analysis.

Kreutz C, Schmidt ME, Steindorf K.

Breast Cancer Res Treat. 2019 Jul;176(1):1-15. doi: 10.1007/s10549-019-05217-9. Epub 2019 Apr 6. Review.

PMID:
30955185
8.

Recipes for Analysis of Molecular Networks Using the Data2Dynamics Modeling Environment.

Steiert B, Kreutz C, Raue A, Timmer J.

Methods Mol Biol. 2019;1945:341-362. doi: 10.1007/978-1-4939-9102-0_16.

PMID:
30945255
9.

Eukaryotic Translation Elongation is Modulated by Single Natural Nucleotide Derivatives in the Coding Sequences of mRNAs.

Hoernes TP, Heimdörfer D, Köstner D, Faserl K, Nußbaumer F, Plangger R, Kreutz C, Lindner H, Erlacher MD.

Genes (Basel). 2019 Jan 25;10(2). pii: E84. doi: 10.3390/genes10020084.

10.

Benchmark problems for dynamic modeling of intracellular processes.

Hass H, Loos C, Raimúndez-Álvarez E, Timmer J, Hasenauer J, Kreutz C.

Bioinformatics. 2019 Sep 1;35(17):3073-3082. doi: 10.1093/bioinformatics/btz020.

11.

Functional Proteomics of Breast Cancer Metabolism Identifies GLUL as Responder during Hypoxic Adaptation.

Bernhardt S, Tönsing C, Mitra D, Erdem N, Müller-Decker K, Korf U, Kreutz C, Timmer J, Wiemann S.

J Proteome Res. 2019 Mar 1;18(3):1352-1362. doi: 10.1021/acs.jproteome.8b00944. Epub 2019 Jan 18.

PMID:
30609375
12.

The structure of the SAM/SAH-binding riboswitch.

Weickhmann AK, Keller H, Wurm JP, Strebitzer E, Juen MA, Kremser J, Weinberg Z, Kreutz C, Duchardt-Ferner E, Wöhnert J.

Nucleic Acids Res. 2019 Mar 18;47(5):2654-2665. doi: 10.1093/nar/gky1283.

13.

Quantifying post-transcriptional regulation in the development of Drosophila melanogaster.

Becker K, Bluhm A, Casas-Vila N, Dinges N, Dejung M, Sayols S, Kreutz C, Roignant JY, Butter F, Legewie S.

Nat Commun. 2018 Nov 26;9(1):4970. doi: 10.1038/s41467-018-07455-9.

14.

Translation of non-standard codon nucleotides reveals minimal requirements for codon-anticodon interactions.

Hoernes TP, Faserl K, Juen MA, Kremser J, Gasser C, Fuchs E, Shi X, Siewert A, Lindner H, Kreutz C, Micura R, Joseph S, Höbartner C, Westhof E, Hüttenhofer A, Erlacher MD.

Nat Commun. 2018 Nov 19;9(1):4865. doi: 10.1038/s41467-018-07321-8.

15.

5-Oxyacetic Acid Modification Destabilizes Double Helical Stem Structures and Favors Anionic Watson-Crick like cmo5 U-G Base Pairs.

Strebitzer E, Rangadurai A, Plangger R, Kremser J, Juen MA, Tollinger M, Al-Hashimi HM, Kreutz C.

Chemistry. 2018 Dec 17;24(71):18903-18906. doi: 10.1002/chem.201805077. Epub 2018 Nov 20.

16.

Chlorophyll Breakdown in a Fern-Discovery of Phyllobilin Isomers with a Rearranged Carbon Skeleton.

Erhart T, Vergeiner S, Kreutz C, Kräutler B, Müller T.

Angew Chem Int Ed Engl. 2018 Nov 5;57(45):14937-14941. doi: 10.1002/anie.201807818. Epub 2018 Oct 11.

17.

NMR resonance assignments for the SAM/SAH-binding riboswitch RNA bound to S-adenosylhomocysteine.

Weickhmann AK, Keller H, Duchardt-Ferner E, Strebitzer E, Juen MA, Kremser J, Wurm JP, Kreutz C, Wöhnert J.

Biomol NMR Assign. 2018 Oct;12(2):329-334. doi: 10.1007/s12104-018-9834-3. Epub 2018 Jul 26.

PMID:
30051308
18.

A potentially abundant junctional RNA motif stabilized by m6A and Mg2.

Liu B, Merriman DK, Choi SH, Schumacher MA, Plangger R, Kreutz C, Horner SM, Meyer KD, Al-Hashimi HM.

Nat Commun. 2018 Jul 17;9(1):2761. doi: 10.1038/s41467-018-05243-z.

19.

BRAF V600E Mutations in Nevi and Melanocytic Tumors of Uncertain Malignant Potential.

Seitz-Alghrouz R, Hidalgo JV, Kayser C, Kreutz C, Technau-Hafsi K, Diaz C, von Deimling A, Timmer J, Werner M, Malkovsky M, Fisch P.

J Invest Dermatol. 2018 Nov;138(11):2489-2491. doi: 10.1016/j.jid.2018.04.035. Epub 2018 Jul 12. No abstract available.

20.

Studying sparsely populated conformational states in RNA combining chemical synthesis and solution NMR spectroscopy.

Strebitzer E, Nußbaumer F, Kremser J, Tollinger M, Kreutz C.

Methods. 2018 Sep 15;148:39-47. doi: 10.1016/j.ymeth.2018.05.007. Epub 2018 May 31.

21.

Isotope labeling for studying RNA by solid-state NMR spectroscopy.

Marchanka A, Kreutz C, Carlomagno T.

J Biomol NMR. 2018 Jul;71(3):151-164. doi: 10.1007/s10858-018-0180-7. Epub 2018 Apr 12. Review.

PMID:
29651587
22.

CCR5 RNA Pseudoknots: Residue and Site-Specific Labeling correlate Internal Motions with microRNA Binding.

Chen B, Longhini AP, Nußbaumer F, Kreutz C, Dinman JD, Dayie TK.

Chemistry. 2018 Apr 11;24(21):5462-5468. doi: 10.1002/chem.201705948. Epub 2018 Mar 25.

PMID:
29412477
23.

An easy and efficient approach for testing identifiability.

Kreutz C.

Bioinformatics. 2018 Jun 1;34(11):1913-1921. doi: 10.1093/bioinformatics/bty035.

PMID:
29365095
24.

Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release.

Hoernes TP, Clementi N, Juen MA, Shi X, Faserl K, Willi J, Gasser C, Kreutz C, Joseph S, Lindner H, Hüttenhofer A, Erlacher MD.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E382-E389. doi: 10.1073/pnas.1714554115. Epub 2018 Jan 3.

25.

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression.

Lucarelli P, Schilling M, Kreutz C, Vlasov A, Boehm ME, Iwamoto N, Steiert B, Lattermann S, Wäsch M, Stepath M, Matter MS, Heikenwälder M, Hoffmann K, Deharde D, Damm G, Seehofer D, Muciek M, Gretz N, Lehmann WD, Timmer J, Klingmüller U.

Cell Syst. 2018 Jan 24;6(1):75-89.e11. doi: 10.1016/j.cels.2017.11.010. Epub 2017 Dec 13.

26.

Hepatocyte Ploidy Is a Diversity Factor for Liver Homeostasis.

Kreutz C, MacNelly S, Follo M, Wäldin A, Binninger-Lacour P, Timmer J, Bartolomé-Rodríguez MM.

Front Physiol. 2017 Oct 31;8:862. doi: 10.3389/fphys.2017.00862. eCollection 2017.

27.

Chemical synthesis and NMR spectroscopy of long stable isotope labelled RNA.

Kremser J, Strebitzer E, Plangger R, Juen MA, Nußbaumer F, Glasner H, Breuker K, Kreutz C.

Chem Commun (Camb). 2017 Nov 30;53(96):12938-12941. doi: 10.1039/c7cc06747j.

PMID:
29155431
28.

Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.

Tants JN, Fesser S, Kern T, Stehle R, Geerlof A, Wunderlich C, Juen M, Hartlmüller C, Böttcher R, Kunzelmann S, Lange O, Kreutz C, Förstemann K, Sattler M.

Nucleic Acids Res. 2017 Dec 1;45(21):12536-12550. doi: 10.1093/nar/gkx886.

29.

Synthesis and incorporation of 13C-labeled DNA building blocks to probe structural dynamics of DNA by NMR.

Nußbaumer F, Juen MA, Gasser C, Kremser J, Müller T, Tollinger M, Kreutz C.

Nucleic Acids Res. 2017 Sep 6;45(15):9178-9192. doi: 10.1093/nar/gkx592.

30.

Phenylbenzenesulfonates and -sulfonamides as 17β-hydroxysteroid dehydrogenase type 2 inhibitors: Synthesis and SAR-analysis.

Vuorinen A, Engeli RT, Leugger S, Kreutz CR, Schuster D, Odermatt A, Matuszczak B.

Bioorg Med Chem Lett. 2017 Jul 1;27(13):2982-2985. doi: 10.1016/j.bmcl.2017.05.005. Epub 2017 May 4.

PMID:
28506753
31.

Partial break in tolerance of NKG2A-/LIR-1- single KIR+ NK cells early in the course of HLA-matched, KIR-mismatched hematopoietic cell transplantation.

Rathmann S, Keck C, Kreutz C, Weit N, Müller M, Timmer J, Glatzel S, Follo M, Malkovsky M, Werner M, Handgretinger R, Finke J, Fisch P.

Bone Marrow Transplant. 2017 Aug;52(8):1144-1155. doi: 10.1038/bmt.2017.81. Epub 2017 May 8.

PMID:
28481352
32.

The synthesis of 15N(7)-Hoogsteen face-labeled adenosine phosphoramidite for solid-phase RNA synthesis.

Neuner S, Kreutz C, Micura R.

Monatsh Chem. 2017;148(1):149-155. doi: 10.1007/s00706-016-1882-8. Epub 2016 Dec 8.

33.

RNA binding and chaperone activity of the E. coli cold-shock protein CspA.

Rennella E, Sára T, Juen M, Wunderlich C, Imbert L, Solyom Z, Favier A, Ayala I, Weinhäupl K, Schanda P, Konrat R, Kreutz C, Brutscher B.

Nucleic Acids Res. 2017 Apr 20;45(7):4255-4268. doi: 10.1093/nar/gkx044.

34.

Profile likelihood-based analyses of infectious disease models.

Tönsing C, Timmer J, Kreutz C.

Stat Methods Med Res. 2018 Jul;27(7):1979-1998. doi: 10.1177/0962280217746444. Epub 2018 Mar 7.

PMID:
29512437
35.

Measurement of Ligand-Target Residence Times by 1H Relaxation Dispersion NMR Spectroscopy.

Moschen T, Grutsch S, Juen MA, Wunderlich CH, Kreutz C, Tollinger M.

J Med Chem. 2016 Dec 8;59(23):10788-10793. Epub 2016 Nov 29.

36.

A Stably Protonated Adenine Nucleotide with a Highly Shifted pKa Value Stabilizes the Tertiary Structure of a GTP-Binding RNA Aptamer.

Wolter AC, Weickhmann AK, Nasiri AH, Hantke K, Ohlenschläger O, Wunderlich CH, Kreutz C, Duchardt-Ferner E, Wöhnert J.

Angew Chem Int Ed Engl. 2017 Jan 2;56(1):401-404. doi: 10.1002/anie.201609184. Epub 2016 Nov 25.

PMID:
27885761
37.

NMR resonance assignments for the tetramethylrhodamine binding RNA aptamer 3 in complex with the ligand 5-carboxy-tetramethylrhodamine.

Duchardt-Ferner E, Juen M, Kreutz C, Wöhnert J.

Biomol NMR Assign. 2017 Apr;11(1):29-34. doi: 10.1007/s12104-016-9715-6. Epub 2016 Oct 11.

PMID:
27730489
38.

A Thymic Epithelial Stem Cell Pool Persists throughout Ontogeny and Is Modulated by TGF-β.

Ucar O, Li K, Dvornikov D, Kreutz C, Timmer J, Matt S, Brenner L, Smedley C, Travis MA, Hofmann TG, Klingmüller U, Kyewski B.

Cell Rep. 2016 Oct 4;17(2):448-457. doi: 10.1016/j.celrep.2016.09.027.

39.

Driving the Model to Its Limit: Profile Likelihood Based Model Reduction.

Maiwald T, Hass H, Steiert B, Vanlier J, Engesser R, Raue A, Kipkeew F, Bock HH, Kaschek D, Kreutz C, Timmer J.

PLoS One. 2016 Sep 2;11(9):e0162366. doi: 10.1371/journal.pone.0162366. eCollection 2016.

40.

L1 regularization facilitates detection of cell type-specific parameters in dynamical systems.

Steiert B, Timmer J, Kreutz C.

Bioinformatics. 2016 Sep 1;32(17):i718-i726. doi: 10.1093/bioinformatics/btw461.

41.

Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy.

Juen MA, Wunderlich CH, Nußbaumer F, Tollinger M, Kontaxis G, Konrat R, Hansen DF, Kreutz C.

Angew Chem Int Ed Engl. 2016 Sep 19;55(39):12008-12. doi: 10.1002/anie.201605870. Epub 2016 Aug 17.

42.

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells.

Merkle R, Steiert B, Salopiata F, Depner S, Raue A, Iwamoto N, Schelker M, Hass H, Wäsch M, Böhm ME, Mücke O, Lipka DB, Plass C, Lehmann WD, Kreutz C, Timmer J, Schilling M, Klingmüller U.

PLoS Comput Biol. 2016 Aug 5;12(8):e1005049. doi: 10.1371/journal.pcbi.1005049. eCollection 2016 Aug.

43.

m(1)A and m(1)G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs.

Zhou H, Kimsey IJ, Nikolova EN, Sathyamoorthy B, Grazioli G, McSally J, Bai T, Wunderlich CH, Kreutz C, Andricioaei I, Al-Hashimi HM.

Nat Struct Mol Biol. 2016 Sep;23(9):803-10. doi: 10.1038/nsmb.3270. Epub 2016 Aug 1.

44.

Dealing with prognostic signature instability: a strategy illustrated for cardiovascular events in patients with end-stage renal disease.

Binder H, Kurz T, Teschner S, Kreutz C, Geyer M, Donauer J, Kraemer-Guth A, Timmer J, Schumacher M, Walz G.

BMC Med Genomics. 2016 Jul 20;9(1):43. doi: 10.1186/s12920-016-0210-9.

45.

Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.

Ren A, Vušurović N, Gebetsberger J, Gao P, Juen M, Kreutz C, Micura R, Patel DJ.

Nat Chem Biol. 2016 Sep;12(9):702-8. doi: 10.1038/nchembio.2125. Epub 2016 Jul 11.

46.

Chlorophyll Catabolites in Fall Leaves of the Wych Elm Tree Present a Novel Glycosylation Motif.

Scherl M, Müller T, Kreutz CR, Huber RG, Zass E, Liedl KR, Kräutler B.

Chemistry. 2016 Jul 4;22(28):9498-503. doi: 10.1002/chem.201601739. Epub 2016 Jun 6.

47.

Fast integration-based prediction bands for ordinary differential equation models.

Hass H, Kreutz C, Timmer J, Kaschek D.

Bioinformatics. 2016 Apr 15;32(8):1204-10. doi: 10.1093/bioinformatics/btv743. Epub 2015 Dec 17.

PMID:
26685309
48.

Chemo-enzymatic synthesis of site-specific isotopically labeled nucleotides for use in NMR resonance assignment, dynamics and structural characterizations.

Longhini AP, LeBlanc RM, Becette O, Salguero C, Wunderlich CH, Johnson BA, D'Souza VM, Kreutz C, Dayie TK.

Nucleic Acids Res. 2016 Apr 7;44(6):e52. doi: 10.1093/nar/gkv1333. Epub 2015 Dec 10.

49.

Influence of urban area on the water quality of the Campo River basin, Paraná State, Brazil.

Carvalho KQ, Lima SB, Passig FH, Gusmão LK, Souza DC, Kreutz C, Belini AD, Arantes EJ.

Braz J Biol. 2015 Dec;75(4 Suppl 2):S96-106. doi: 10.1590/1519-6984.00413suppl. Epub 2015 Nov 27.

50.

Stable isotope-labeled RNA phosphoramidites to facilitate dynamics by NMR.

Wunderlich CH, Juen MA, LeBlanc RM, Longhini AP, Dayie TK, Kreutz C.

Methods Enzymol. 2015;565:461-94. doi: 10.1016/bs.mie.2015.06.013. Epub 2015 Jul 9.

PMID:
26577742

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