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Modular microfluidic systems cast from 3D-printed molds for imaging leukocyte adherence to differentially treated endothelial cultures.

Hernández Vera R, O'Callaghan P, Fatsis-Kavalopoulos N, Kreuger J.

Sci Rep. 2019 Aug 5;9(1):11321. doi: 10.1038/s41598-019-47475-z.


Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution.

Fatsis-Kavalopoulos N, O'Callaghan P, Xie B, Hernández Vera R, Idevall-Hagren O, Kreuger J.

Lab Chip. 2019 Mar 13;19(6):1071-1081. doi: 10.1039/c8lc01153b.


TIMFIE Sampler-A New Time-Integrating, Active, Low-Tech Sampling Device for Quantitative Monitoring of Pesticides in Whole Water.

Jonsson O, Paulsson E, Kreuger J.

Environ Sci Technol. 2019 Jan 2;53(1):279-286. doi: 10.1021/acs.est.8b02966. Epub 2018 Dec 20.


Modeling the structural implications of an alternatively spliced Exoc3l2, a paralog of the tunneling nanotube-forming M-Sec.

O'Callaghan P, Zarb Y, Noborn F, Kreuger J.

PLoS One. 2018 Aug 7;13(8):e0201557. doi: 10.1371/journal.pone.0201557. eCollection 2018.


Concentrations, fluxes and field calibration of passive water samplers for pesticides and hazard-based risk assessment.

Ahrens L, Daneshvar A, Lau AE, Kreuger J.

Sci Total Environ. 2018 Oct 1;637-638:835-843. doi: 10.1016/j.scitotenv.2018.05.039. Epub 2018 May 12.


FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation.

Heldin J, O'Callaghan P, Hernández Vera R, Fuchs PF, Gerwins P, Kreuger J.

Cell Signal. 2017 Dec;40:125-132. doi: 10.1016/j.cellsig.2017.09.009. Epub 2017 Sep 18.


Spatial and temporal patterns of pesticide concentrations in streamflow, drainage and runoff in a small Swedish agricultural catchment.

Sandin M, Piikki K, Jarvis N, Larsbo M, Bishop K, Kreuger J.

Sci Total Environ. 2018 Jan 1;610-611:623-634. doi: 10.1016/j.scitotenv.2017.08.068. Epub 2017 Aug 17.


Vascular sprouts induce local attraction of proangiogenic neutrophils.

Christoffersson G, Lomei J, O'Callaghan P, Kreuger J, Engblom S, Phillipson M.

J Leukoc Biol. 2017 Sep;102(3):741-751. doi: 10.1189/jlb.1MA0117-018R. Epub 2017 Jun 5.


Pesticides from wastewater treatment plant effluents affect invertebrate communities.

Münze R, Hannemann C, Orlinskiy P, Gunold R, Paschke A, Foit K, Becker J, Kaske O, Paulsson E, Peterson M, Jernstedt H, Kreuger J, Schüürmann G, Liess M.

Sci Total Environ. 2017 Dec 1;599-600:387-399. doi: 10.1016/j.scitotenv.2017.03.008. Epub 2017 May 5.


Pesticide mixtures in the Swedish streams: Environmental risks, contributions of individual compounds and consequences of single-substance oriented risk mitigation.

Gustavsson M, Kreuger J, Bundschuh M, Backhaus T.

Sci Total Environ. 2017 Nov 15;598:973-983. doi: 10.1016/j.scitotenv.2017.04.122. Epub 2017 Apr 29.


The atypical Rho GTPase RhoD is a regulator of actin cytoskeleton dynamics and directed cell migration.

Blom M, Reis K, Heldin J, Kreuger J, Aspenström P.

Exp Cell Res. 2017 Mar 15;352(2):255-264. doi: 10.1016/j.yexcr.2017.02.013. Epub 2017 Feb 11.


A Modular and Affordable Time-Lapse Imaging and Incubation System Based on 3D-Printed Parts, a Smartphone, and Off-The-Shelf Electronics.

Hernández Vera R, Schwan E, Fatsis-Kavalopoulos N, Kreuger J.

PLoS One. 2016 Dec 21;11(12):e0167583. doi: 10.1371/journal.pone.0167583. eCollection 2016.


Failure to Genotype: A Cautionary Note on an Elusive loxP Sequence.

Kreuger J, O'Callaghan P.

PLoS One. 2016 Oct 21;11(10):e0165012. doi: 10.1371/journal.pone.0165012. eCollection 2016.


Characterization and Application of Passive Samplers for Monitoring of Pesticides in Water.

Ahrens L, Daneshvar A, Lau AE, Kreuger J.

J Vis Exp. 2016 Aug 3;(114). doi: 10.3791/54053.


Environmental monitoring of pesticide exposure and effects on mangrove aquatic organisms of Mozambique.

Sturve J, Scarlet P, Halling M, Kreuger J, Macia A.

Mar Environ Res. 2016 Oct;121:9-19. doi: 10.1016/j.marenvres.2016.05.005. Epub 2016 Jun 23.


Surface Runoff of Pesticides from a Clay Loam Field in Sweden.

Larsbo M, Sandin M, Jarvis N, Etana A, Kreuger J.

J Environ Qual. 2016 Jul;45(4):1367-74. doi: 10.2134/jeq2015.10.0528.


Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicing.

Heindryckx F, Binet F, Ponticos M, Rombouts K, Lau J, Kreuger J, Gerwins P.

EMBO Mol Med. 2016 Jul 1;8(7):729-44. doi: 10.15252/emmm.201505925. Print 2016 Jul.


Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis.

Kreuger J, Phillipson M.

Nat Rev Drug Discov. 2016 Feb;15(2):125-42. doi: 10.1038/nrd.2015.2. Epub 2015 Nov 27. Review.


Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans.

Massena S, Christoffersson G, Vågesjö E, Seignez C, Gustafsson K, Binet F, Herrera Hidalgo C, Giraud A, Lomei J, Weström S, Shibuya M, Claesson-Welsh L, Gerwins P, Welsh M, Kreuger J, Phillipson M.

Blood. 2015 Oct 22;126(17):2016-26. doi: 10.1182/blood-2015-03-631572. Epub 2015 Aug 18.


The legacy of pesticide pollution: An overlooked factor in current risk assessments of freshwater systems.

Rasmussen JJ, Wiberg-Larsen P, Baattrup-Pedersen A, Cedergreen N, McKnight US, Kreuger J, Jacobsen D, Kristensen EA, Friberg N.

Water Res. 2015 Nov 1;84:25-32. doi: 10.1016/j.watres.2015.07.021. Epub 2015 Jul 15.


Characterization of five passive sampling devices for monitoring of pesticides in water.

Ahrens L, Daneshvar A, Lau AE, Kreuger J.

J Chromatogr A. 2015 Jul 31;1405:1-11. doi: 10.1016/j.chroma.2015.05.044. Epub 2015 May 29.


Direct and indirect effects of climate change on herbicide leaching--a regional scale assessment in Sweden.

Steffens K, Jarvis N, Lewan E, Lindström B, Kreuger J, Kjellström E, Moeys J.

Sci Total Environ. 2015 May 1;514:239-49. doi: 10.1016/j.scitotenv.2014.12.049. Epub 2015 Feb 7.


VEGF suppresses T-lymphocyte infiltration in the tumor microenvironment through inhibition of NF-κB-induced endothelial activation.

Huang H, Langenkamp E, Georganaki M, Loskog A, Fuchs PF, Dieterich LC, Kreuger J, Dimberg A.

FASEB J. 2015 Jan;29(1):227-38. doi: 10.1096/fj.14-250985. Epub 2014 Oct 31.


Evaluation of pesticide monitoring strategies in agricultural streams based on the toxic-unit concept--experiences from long-term measurements.

Bundschuh M, Goedkoop W, Kreuger J.

Sci Total Environ. 2014 Jun 15;484:84-91. doi: 10.1016/j.scitotenv.2014.03.015. Epub 2014 Mar 29.


MicroRNA-24 suppression of N-deacetylase/N-sulfotransferase-1 (NDST1) reduces endothelial cell responsiveness to vascular endothelial growth factor A (VEGFA).

Kasza Z, Fredlund Fuchs P, Tamm C, Eriksson AS, O'Callaghan P, Heindryckx F, Spillmann D, Larsson E, Le Jan S, Eriksson I, Gerwins P, Kjellén L, Kreuger J.

J Biol Chem. 2013 Sep 6;288(36):25956-63. doi: 10.1074/jbc.M113.484360. Epub 2013 Jul 24.


Childbirth freedom fighters.

Gordon W, Menzel A, McCulloch J, Roach JM, Booker C, Joseph J, Greenwood N, Wood LS, Robinson TG, Gerke N, Kennedy A, van Roojen M, Aurilio D, Kass E, Basile M, Phillips A, Casey B, Spicer G, Raum C, Novak M, Heffernan A, Linstad J, Corcoran D, Lawler RT, Corbeil E, Kali K, Moffat A, Hill M, Ebers B, Zaslow R, Kimball O, Cherney AM, Hannon G, Scar D, Folin A, Potter B, Vergo A, Lucido-Conate J, Hydeman T, Fontaine M, Kinne MH, Hirsch A, Haines K, Ceremy J, Davis S, Goldberger J, Herman D, Kamara M, Cockrill M, Carnesciali M, Hill T, Plaskett N, Fairman A, Darlin J, Morales N, Islam T, Effland K, Viehmann K, German E, Tenney E, Churness D, Myers S, Jones S, Burke B, McLaughlin EY, Pickard K, Cook SS, Kreuger J, Muza S, Hart L, Parsons M, Hodges S, Four R, Bey A, Clem L, Payne S, Phoenix A, Wilkes A, Reiner ES, Ryerson G, Tanner SL, Francis B, Palagi T, Whitley L, Chorley H, Porter M, Moore L, Sampson A, Seruntine L, Levine A, Everett L, Lawlor M, Simkins G, Cole ER, Lane E, Maisonville M, Pretlow A, Deggins N.

Midwifery Today Int Midwife. 2013 Summer;(106):62-3. No abstract available.


Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development.

Filipek-Górniok B, Holmborn K, Haitina T, Habicher J, Oliveira MB, Hellgren C, Eriksson I, Kjellén L, Kreuger J, Ledin J.

Dev Dyn. 2013 Aug;242(8):964-75. doi: 10.1002/dvdy.23981. Epub 2013 Jun 18.


Spatial variation in herbicide leaching from a marine clay soil via subsurface drains.

Ulén BM, Larsbo M, Kreuger JK, Svanbäck A.

Pest Manag Sci. 2014 Mar;70(3):405-14. doi: 10.1002/ps.3574. Epub 2013 Jun 13.


Toxicity of 15 veterinary pharmaceuticals in zebrafish (Danio rerio) embryos.

Carlsson G, Patring J, Kreuger J, Norrgren L, Oskarsson A.

Aquat Toxicol. 2013 Jan 15;126:30-41. doi: 10.1016/j.aquatox.2012.10.008. Epub 2012 Oct 22.


Heparan sulfate biosynthesis: regulation and variability.

Kreuger J, Kjellén L.

J Histochem Cytochem. 2012 Dec;60(12):898-907. doi: 10.1369/0022155412464972. Epub 2012 Oct 4. Review.


On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis.

Holmborn K, Habicher J, Kasza Z, Eriksson AS, Filipek-Gorniok B, Gopal S, Couchman JR, Ahlberg PE, Wiweger M, Spillmann D, Kreuger J, Ledin J.

J Biol Chem. 2012 Sep 28;287(40):33905-16. Epub 2012 Aug 6.


Functional overlap between chondroitin and heparan sulfate proteoglycans during VEGF-induced sprouting angiogenesis.

Le Jan S, Hayashi M, Kasza Z, Eriksson I, Bishop JR, Weibrecht I, Heldin J, Holmborn K, Jakobsson L, Söderberg O, Spillmann D, Esko JD, Claesson-Welsh L, Kjellén L, Kreuger J.

Arterioscler Thromb Vasc Biol. 2012 May;32(5):1255-63. doi: 10.1161/ATVBAHA.111.240622. Epub 2012 Feb 16.


Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells.

Barkefors I, Fuchs PF, Heldin J, Bergström T, Forsberg-Nilsson K, Kreuger J.

J Biol Chem. 2011 Jul 8;286(27):24189-99. doi: 10.1074/jbc.M110.212209. Epub 2011 May 12.


Spray drift as influenced by meteorological and technical factors.

Arvidsson T, Bergström L, Kreuger J.

Pest Manag Sci. 2011 May;67(5):586-98. doi: 10.1002/ps.2114. Epub 2011 Feb 28.


Comparison of collectors of airborne spray drift. Experiments in a wind tunnel and field measurements.

Arvidsson T, Bergström L, Kreuger J.

Pest Manag Sci. 2011 Jun;67(6):725-33. doi: 10.1002/ps.2115. Epub 2011 Mar 28.


VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts.

Nilsson I, Bahram F, Li X, Gualandi L, Koch S, Jarvius M, Söderberg O, Anisimov A, Kholová I, Pytowski B, Baldwin M, Ylä-Herttuala S, Alitalo K, Kreuger J, Claesson-Welsh L.

EMBO J. 2010 Apr 21;29(8):1377-88. doi: 10.1038/emboj.2010.30. Epub 2010 Mar 11.


Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1.

Larsson E, Fredlund Fuchs P, Heldin J, Barkefors I, Bondjers C, Genové G, Arrondel C, Gerwins P, Kurschat C, Schermer B, Benzing T, Harvey SJ, Kreuger J, Lindahl P.

Genome Med. 2009 Nov 16;1(11):108. doi: 10.1186/gm108.


A fluidic device to study directional angiogenesis in complex tissue and organ culture models.

Barkefors I, Thorslund S, Nikolajeff F, Kreuger J.

Lab Chip. 2009 Feb 21;9(4):529-35. doi: 10.1039/b814691h. Epub 2008 Dec 4.


Endothelial cell migration in stable gradients of vascular endothelial growth factor A and fibroblast growth factor 2: effects on chemotaxis and chemokinesis.

Barkefors I, Le Jan S, Jakobsson L, Hejll E, Carlson G, Johansson H, Jarvius J, Park JW, Li Jeon N, Kreuger J.

J Biol Chem. 2008 May 16;283(20):13905-12. doi: 10.1074/jbc.M704917200. Epub 2008 Mar 17.


Inflammation-related genes up-regulated in schizophrenia brains.

Saetre P, Emilsson L, Axelsson E, Kreuger J, Lindholm E, Jazin E.

BMC Psychiatry. 2007 Sep 6;7:46. Review.


Building blood vessels--stem cell models in vascular biology.

Jakobsson L, Kreuger J, Claesson-Welsh L.

J Cell Biol. 2007 Jun 4;177(5):751-5. Epub 2007 May 29. Review.


On the role of glypicans in the process of morphogen gradient formation.

Hufnagel L, Kreuger J, Cohen SM, Shraiman BI.

Dev Biol. 2006 Dec 15;300(2):512-22. Epub 2006 Sep 19.


Interactions between heparan sulfate and proteins: the concept of specificity.

Kreuger J, Spillmann D, Li JP, Lindahl U.

J Cell Biol. 2006 Jul 31;174(3):323-7. Review.


Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis.

Jakobsson L, Kreuger J, Holmborn K, Lundin L, Eriksson I, Kjellén L, Claesson-Welsh L.

Dev Cell. 2006 May;10(5):625-34.


VEGF receptor signalling - in control of vascular function.

Olsson AK, Dimberg A, Kreuger J, Claesson-Welsh L.

Nat Rev Mol Cell Biol. 2006 May;7(5):359-71. Review.


Early lymph vessel development from embryonic stem cells.

Kreuger J, Nilsson I, Kerjaschki D, Petrova T, Alitalo K, Claesson-Welsh L.

Arterioscler Thromb Vasc Biol. 2006 May;26(5):1073-8. Epub 2006 Mar 16.


Stochastic modeling of diffuse pesticide losses from a small agricultural catchment.

Lindahl AM, Kreuger J, Stenström J, Gärdenäs AI, Alavi G, Roulier S, Jarvis NJ.

J Environ Qual. 2005 Jun 7;34(4):1174-85. Print 2005 Jul-Aug.


Fibroblast growth factors share binding sites in heparan sulphate.

Kreuger J, Jemth P, Sanders-Lindberg E, Eliahu L, Ron D, Basilico C, Salmivirta M, Lindahl U.

Biochem J. 2005 Jul 1;389(Pt 1):145-50.


Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity.

Kreuger J, Perez L, Giraldez AJ, Cohen SM.

Dev Cell. 2004 Oct;7(4):503-12.

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