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Items: 1 to 50 of 282

1.

Serum amyloid A and Janus kinase 2 in a mouse model of diabetic kidney disease.

Dieter BP, Meek RL, Anderberg RJ, Cooney SK, Bergin JL, Zhang H, Nair V, Kretzler M, Brosius FC, Tuttle KR.

PLoS One. 2019 Feb 14;14(2):e0211555. doi: 10.1371/journal.pone.0211555. eCollection 2019.

2.

Correlation Between Baseline GFR and Subsequent Change in GFR in Norwegian Adults Without Diabetes and in Pima Indians.

Melsom T, Nair V, Schei J, Mariani L, Stefansson VTN, Harder JL, Jenssen TG, Solbu MD, Norvik JV, Looker H, Knowler WC, Kretzler M, Nelson RG, Eriksen BO.

Am J Kidney Dis. 2019 Jan 28. pii: S0272-6386(19)30001-0. doi: 10.1053/j.ajkd.2018.11.011. [Epub ahead of print]

PMID:
30704883
3.

Organoid single cell profiling identifies a transcriptional signature of glomerular disease.

Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, Spence JR, Bitzer M, Troyanskaya OG, Hodgin JB, Wiggins RC, Freedman BS, Kretzler M; European Renal cDNA Bank (ERCB); Nephrotic Syndrome Study Network (NEPTUNE).

JCI Insight. 2019 Jan 10;4(1). pii: 122697. doi: 10.1172/jci.insight.122697. [Epub ahead of print]

4.

Decoding the genetic determinants of gene regulation in the kidney.

Nair V, Kretzler M.

Kidney Int. 2019 Jan;95(1):16-18. doi: 10.1016/j.kint.2018.11.013. No abstract available.

PMID:
30606414
5.

Soluble ST2 and Galectin-3 and Progression of CKD.

Alam ML, Katz R, Bellovich KA, Bhat ZY, Brosius FC, de Boer IH, Gadegbeku CA, Gipson DS, Hawkins JJ, Himmelfarb J, Kestenbaum BR, Kretzler M, Robinson-Cohen C, Steigerwalt SP, Tuegel C, Bansal N.

Kidney Int Rep. 2018 Sep 21;4(1):103-111. doi: 10.1016/j.ekir.2018.09.013. eCollection 2019 Jan.

6.

Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study.

Selewski DT, Ambruzs JM, Appel GB, Bomback AS, Matar RB, Cai Y, Cattran DC, Chishti AS, D'Agati VD, D'Alessandri-Silva CJ, Gbadegesin RA, Hogan JJ, Iragorri S, Jennette JC, Julian BA, Khalid M, Lafayette RA, Liapis H, Lugani F, Mansfield SA, Mason S, Nachman PH, Nast CC, Nester CM, Noone DG, Novak J, O'Shaughnessy MM, Reich HN, Rheault MN, Rizk DV, Saha MK, Sanghani NS, Sperati CJ, Sreedharan R, Srivastava T, Swiatecka-Urban A, Twombley K, Vasylyeva TL, Weaver DJ, Yin H, Zee J, Falk RJ, Gharavi AG, Gillespie BW, Gipson DS, Greenbaum LA, Holzman LB, Kretzler M, Robinson BM, Smoyer WE, Flessner M, Guay-Woodford LM, Kiryluk K; CureGN Consortium.

Kidney Int Rep. 2018 Aug 3;3(6):1373-1384. doi: 10.1016/j.ekir.2018.07.021. eCollection 2018 Nov.

7.

Consent for Genetic Biobanking in a Diverse Multisite CKD Cohort.

Troost JP, Hawkins J, Jenkins DR, Gipson DS, Kretzler M, El Shamy O, Bellovich K, Perumal K, Bhat Z, Massengill S, Steigerwalt S, Pennathur S, Brosius FC, Gadegbeku CA; Michigan O’Brien Kidney Translational Research Center.

Kidney Int Rep. 2018 Jun 12;3(6):1267-1275. doi: 10.1016/j.ekir.2018.06.002. eCollection 2018 Nov.

8.

Tyro3 is a podocyte protective factor in glomerular disease.

Zhong F, Chen Z, Zhang L, Xie Y, Nair V, Ju W, Kretzler M, Nelson RG, Li Z, Chen H, Wang Y, Zhang A, Lee K, Liu Z, He JC.

JCI Insight. 2018 Nov 15;3(22). pii: 123482. doi: 10.1172/jci.insight.123482. [Epub ahead of print]

9.

CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease.

Mariani LH, Bomback AS, Canetta PA, Flessner MF, Helmuth M, Hladunewich MA, Hogan JJ, Kiryluk K, Nachman PH, Nast CC, Rheault MN, Rizk DV, Trachtman H, Wenderfer SE, Bowers C, Hill-Callahan P, Marasa M, Poulton CJ, Revell A, Vento S, Barisoni L, Cattran D, D'Agati V, Jennette JC, Klein JB, Laurin LP, Twombley K, Falk RJ, Gharavi AG, Gillespie BW, Gipson DS, Greenbaum LA, Holzman LB, Kretzler M, Robinson B, Smoyer WE, Guay-Woodford LM; CureGN Consortium.

Am J Kidney Dis. 2019 Feb;73(2):218-229. doi: 10.1053/j.ajkd.2018.07.020. Epub 2018 Nov 9.

PMID:
30420158
10.

Hydroxypropyl-β-cyclodextrin protects from kidney disease in experimental Alport syndrome and focal segmental glomerulosclerosis.

Mitrofanova A, Molina J, Varona Santos J, Guzman J, Morales XA, Ducasa GM, Bryn J, Sloan A, Volosenco I, Kim JJ, Ge M, Mallela SK, Kretzler M, Eddy S, Martini S, Wahl P, Pastori S, Mendez AJ, Burke GW, Merscher S, Fornoni A.

Kidney Int. 2018 Dec;94(6):1151-1159. doi: 10.1016/j.kint.2018.06.031. Epub 2018 Oct 6.

PMID:
30301568
11.

An integrative systems biology approach for precision medicine in diabetic kidney disease.

Mulder S, Hamidi H, Kretzler M, Ju W.

Diabetes Obes Metab. 2018 Oct;20 Suppl 3:6-13. doi: 10.1111/dom.13416. Review.

PMID:
30294956
12.

a-f BLAST: Non-Iterative Radial k-t BLAST Reconstruction for Real-Time Imaging.

Kretzler M, Hamilton J, Griswold M, Seiberlich N.

IEEE Trans Med Imaging. 2018 Sep 27. doi: 10.1109/TMI.2018.2872419. [Epub ahead of print]

PMID:
30273146
13.

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney.

Menon R, Otto EA, Kokoruda A, Zhou J, Zhang Z, Yoon E, Chen YC, Troyanskaya O, Spence JR, Kretzler M, Cebrián C.

Development. 2018 Aug 30;145(16). pii: dev164038. doi: 10.1242/dev.164038.

14.

JAK-STAT signaling is activated in the kidney and peripheral blood cells of patients with focal segmental glomerulosclerosis.

Tao J, Mariani L, Eddy S, Maecker H, Kambham N, Mehta K, Hartman J, Wang W, Kretzler M, Lafayette RA.

Kidney Int. 2018 Oct;94(4):795-808. doi: 10.1016/j.kint.2018.05.022. Epub 2018 Aug 6.

PMID:
30093081
15.

Systems biology approaches to identify disease mechanisms and facilitate targeted therapy in the management of glomerular disease.

Hamidi H, Kretzler M.

Curr Opin Nephrol Hypertens. 2018 Nov;27(6):433-439. doi: 10.1097/MNH.0000000000000446.

PMID:
30074515
16.

An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome.

Gillies CE, Putler R, Menon R, Otto E, Yasutake K, Nair V, Hoover P, Lieb D, Li S, Eddy S, Fermin D, McNulty MT; Nephrotic Syndrome Study Network (NEPTUNE), Hacohen N, Kiryluk K, Kretzler M, Wen X, Sampson MG.

Am J Hum Genet. 2018 Aug 2;103(2):232-244. doi: 10.1016/j.ajhg.2018.07.004. Epub 2018 Jul 26.

17.

Single-Cell Sequencing the Glomerulus, Unraveling the Molecular Programs of Glomerular Filtration, One Cell at a Time.

Kretzler M, Menon R.

J Am Soc Nephrol. 2018 Aug;29(8):2036-2038. doi: 10.1681/ASN.2018060626. Epub 2018 Jul 12. No abstract available.

PMID:
30002221
18.

Renal matrix Gla protein expression increases progressively with CKD and predicts renal outcome.

Miyata KN, Nast CC, Dai T, Dukkipati R, LaPage JA, Troost JP, Schurgers LJ, Kretzler M, Adler SG.

Exp Mol Pathol. 2018 Aug;105(1):120-129. doi: 10.1016/j.yexmp.2018.07.001. Epub 2018 Jul 6.

19.

Validation of Plasma Biomarker Candidates for the Prediction of eGFR Decline in Patients With Type 2 Diabetes.

Heinzel A, Kammer M, Mayer G, Reindl-Schwaighofer R, Hu K, Perco P, Eder S, Rosivall L, Mark PB, Ju W, Kretzler M, Gilmour P, Wilson JM, Duffin KL, Abdalla M, McCarthy MI, Heinze G, Heerspink HL, Wiecek A, Gomez MF, Oberbauer R; BEAt-DKD Consortium.

Diabetes Care. 2018 Sep;41(9):1947-1954. doi: 10.2337/dc18-0532. Epub 2018 Jul 6.

PMID:
29980527
20.

Urinary epidermal growth factor as a prognostic marker for the progression of Alport syndrome in children.

Li B, Zhang Y, Wang F, Nair V, Ding F, Xiao H, Yao Y, Kretzler M, Ju W, Ding J.

Pediatr Nephrol. 2018 Oct;33(10):1731-1739. doi: 10.1007/s00467-018-3988-1. Epub 2018 Jun 11.

21.

Transethnic, Genome-Wide Analysis Reveals Immune-Related Risk Alleles and Phenotypic Correlates in Pediatric Steroid-Sensitive Nephrotic Syndrome.

Debiec H, Dossier C, Letouzé E, Gillies CE, Vivarelli M, Putler RK, Ars E, Jacqz-Aigrain E, Elie V, Colucci M, Debette S, Amouyel P, Elalaoui SC, Sefiani A, Dubois V, Simon T, Kretzler M, Ballarin J, Emma F, Sampson MG, Deschênes G, Ronco P.

J Am Soc Nephrol. 2018 Jul;29(7):2000-2013. doi: 10.1681/ASN.2017111185. Epub 2018 Jun 14.

PMID:
29903748
22.

GDF-15, Galectin 3, Soluble ST2, and Risk of Mortality and Cardiovascular Events in CKD.

Tuegel C, Katz R, Alam M, Bhat Z, Bellovich K, de Boer I, Brosius F, Gadegbeku C, Gipson D, Hawkins J, Himmelfarb J, Ju W, Kestenbaum B, Kretzler M, Robinson-Cohen C, Steigerwalt S, Bansal N.

Am J Kidney Dis. 2018 Oct;72(4):519-528. doi: 10.1053/j.ajkd.2018.03.025. Epub 2018 Jun 14.

PMID:
29866459
23.

High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping.

Czerniecki SM, Cruz NM, Harder JL, Menon R, Annis J, Otto EA, Gulieva RE, Islas LV, Kim YK, Tran LM, Martins TJ, Pippin JW, Fu H, Kretzler M, Shankland SJ, Himmelfarb J, Moon RT, Paragas N, Freedman BS.

Cell Stem Cell. 2018 Jun 1;22(6):929-940.e4. doi: 10.1016/j.stem.2018.04.022. Epub 2018 May 17.

PMID:
29779890
24.

Renal Pre-Competitive Consortium (RPC2): discovering therapeutic targets together.

Tomilo M, Ascani H, Mirel B, Magnone MC, Quinn CM, Karihaloo A, Duffin K, Patel UD, Kretzler M.

Drug Discov Today. 2018 Oct;23(10):1695-1699. doi: 10.1016/j.drudis.2018.05.021. Epub 2018 May 18.

PMID:
29778696
25.

Metabolic pathways and immunometabolism in rare kidney diseases.

Grayson PC, Eddy S, Taroni JN, Lightfoot YL, Mariani L, Parikh H, Lindenmeyer MT, Ju W, Greene CS, Godfrey B, Cohen CD, Krischer J, Kretzler M, Merkel PA; Vasculitis Clinical Research Consortium, the European Renal cDNA Bank cohort, and the Nephrotic Syndrome Study Network.

Ann Rheum Dis. 2018 Aug;77(8):1226-1233. doi: 10.1136/annrheumdis-2017-212935. Epub 2018 May 3.

26.

Urinary epidermal growth factor predicts renal prognosis in antineutrophil cytoplasmic antibody-associated vasculitis.

Wu L, Li XQ, Goyal T, Eddy S, Kretzler M, Ju WJ, Chen M, Zhao MH.

Ann Rheum Dis. 2018 Sep;77(9):1339-1344. doi: 10.1136/annrheumdis-2017-212578. Epub 2018 May 3.

PMID:
29724728
27.

FAR2 is associated with kidney disease in mice and humans.

Backer G, Eddy S, Sheehan SM, Takemon Y, Reznichenko A, Savage HS, Kretzler M, Korstanje R.

Physiol Genomics. 2018 Aug 1;50(8):543-552. doi: 10.1152/physiolgenomics.00118.2017. Epub 2018 Apr 13.

PMID:
29652635
28.

JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trial.

Tuttle KR, Brosius FC 3rd, Adler SG, Kretzler M, Mehta RL, Tumlin JA, Tanaka Y, Haneda M, Liu J, Silk ME, Cardillo TE, Duffin KL, Haas JV, Macias WL, Nunes FP, Janes JM.

Nephrol Dial Transplant. 2018 Nov 1;33(11):1950-1959. doi: 10.1093/ndt/gfx377.

29.

Shared and distinct lipid-lipid interactions in plasma and affected tissues in a diabetic mouse model.

Sas KM, Lin J, Rajendiran TM, Soni T, Nair V, Hinder LM, Jagadish HV, Gardner TW, Abcouwer SF, Brosius FC 3rd, Feldman EL, Kretzler M, Michailidis G, Pennathur S.

J Lipid Res. 2018 Feb;59(2):173-183. doi: 10.1194/jlr.M077222. Epub 2017 Dec 13.

30.

ORAI channels are critical for receptor-mediated endocytosis of albumin.

Zeng B, Chen GL, Garcia-Vaz E, Bhandari S, Daskoulidou N, Berglund LM, Jiang H, Hallett T, Zhou LP, Huang L, Xu ZH, Nair V, Nelson RG, Ju W, Kretzler M, Atkin SL, Gomez MF, Xu SZ.

Nat Commun. 2017 Dec 4;8(1):1920. doi: 10.1038/s41467-017-02094-y.

31.

An Outcomes-Based Definition of Proteinuria Remission in Focal Segmental Glomerulosclerosis.

Troost JP, Trachtman H, Nachman PH, Kretzler M, Spino C, Komers R, Tuller S, Perumal K, Massengill SF, Kamil ES, Oh G, Selewski DT, Gipson P, Gipson DS.

Clin J Am Soc Nephrol. 2018 Mar 7;13(3):414-421. doi: 10.2215/CJN.04780517. Epub 2017 Nov 22.

PMID:
29167190
32.

Novel avenues for drug discovery in diabetic kidney disease.

Breyer MD, Kretzler M.

Expert Opin Drug Discov. 2018 Jan;13(1):65-74. doi: 10.1080/17460441.2018.1398731. Epub 2017 Nov 16. Review.

PMID:
29145743
33.

Metabolomics and Gene Expression Analysis Reveal Down-regulation of the Citric Acid (TCA) Cycle in Non-diabetic CKD Patients.

Hallan S, Afkarian M, Zelnick LR, Kestenbaum B, Sharma S, Saito R, Darshi M, Barding G, Raftery D, Ju W, Kretzler M, Sharma K, de Boer IH.

EBioMedicine. 2017 Dec;26:68-77. doi: 10.1016/j.ebiom.2017.10.027. Epub 2017 Oct 31.

34.

A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome.

Nair V, Komorowsky CV, Weil EJ, Yee B, Hodgin J, Harder JL, Godfrey B, Ju W, Boustany-Kari CM, Schwarz M, Lemley KV, Nelson PJ, Nelson RG, Kretzler M.

Kidney Int. 2018 Feb;93(2):439-449. doi: 10.1016/j.kint.2017.08.013. Epub 2017 Oct 18.

35.

Defining Renal Neoplastic Disease, One Cell at a Time: Mass Cytometry, a New Tool for the Study of Kidney Biology and Disease.

Nelson PJ, Kretzler M.

Am J Kidney Dis. 2017 Dec;70(6):758-761. doi: 10.1053/j.ajkd.2017.08.009. Epub 2017 Oct 12. No abstract available.

PMID:
29031857
36.

Strategies to improve monitoring disease progression, assessing cardiovascular risk, and defining prognostic biomarkers in chronic kidney disease.

Pena MJ, Stenvinkel P, Kretzler M, Adu D, Agarwal SK, Coresh J, Feldman HI, Fogo AB, Gansevoort RT, Harris DC, Jha V, Liu ZH, Luyckx VA, Massy ZA, Mehta R, Nelson RG, O'Donoghue DJ, Obrador GT, Roberts CJ, Sola L, Sumaili EK, Tatiyanupanwong S, Thomas B, Wiecek A, Parikh CR, Heerspink HJL.

Kidney Int Suppl (2011). 2017 Oct;7(2):107-113. doi: 10.1016/j.kisu.2017.07.005. Epub 2017 Sep 20. Review.

37.

Genetic and environmental risk factors for chronic kidney disease.

Obrador GT, Schultheiss UT, Kretzler M, Langham RG, Nangaku M, Pecoits-Filho R, Pollock C, Rossert J, Correa-Rotter R, Stenvinkel P, Walker R, Yang CW, Fox CS, Köttgen A.

Kidney Int Suppl (2011). 2017 Oct;7(2):88-106. doi: 10.1016/j.kisu.2017.07.004. Epub 2017 Sep 20. Review.

38.

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts.

Shved N, Warsow G, Eichinger F, Hoogewijs D, Brandt S, Wild P, Kretzler M, Cohen CD, Lindenmeyer MT.

Sci Rep. 2017 Aug 17;7(1):8576. doi: 10.1038/s41598-017-08492-y.

39.

FSGS as an Adaptive Response to Growth-Induced Podocyte Stress.

Nishizono R, Kikuchi M, Wang SQ, Chowdhury M, Nair V, Hartman J, Fukuda A, Wickman L, Hodgin JB, Bitzer M, Naik A, Wiggins J, Kretzler M, Wiggins RC.

J Am Soc Nephrol. 2017 Oct;28(10):2931-2945. doi: 10.1681/ASN.2017020174. Epub 2017 Jul 18.

40.

Myeloperoxidase Levels and Its Product 3-Chlorotyrosine Predict Chronic Kidney Disease Severity and Associated Coronary Artery Disease.

Afshinnia F, Zeng L, Byun J, Gadegbeku CA, Magnone MC, Whatling C, Valastro B, Kretzler M, Pennathur S; Michigan Kidney Translational Core CPROBE Investigator Group.

Am J Nephrol. 2017;46(1):73-81. doi: 10.1159/000477766. Epub 2017 Jul 1.

41.

Renal biopsy-driven molecular target identification in glomerular disease.

Lindenmeyer MT, Kretzler M.

Pflugers Arch. 2017 Aug;469(7-8):1021-1028. doi: 10.1007/s00424-017-2006-y. Epub 2017 Jun 29. Review.

PMID:
28664406
42.

Blood Pressure and Visit-to-Visit Blood Pressure Variability Among Individuals With Primary Proteinuric Glomerulopathies.

Sethna CB, Meyers KEC, Mariani LH, Psoter KJ, Gadegbeku CA, Gibson KL, Srivastava T, Kretzler M, Brady TM.

Hypertension. 2017 Aug;70(2):315-323. doi: 10.1161/HYPERTENSIONAHA.117.09475. Epub 2017 Jun 26.

43.

Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy.

Liu P, Lassén E, Nair V, Berthier CC, Suguro M, Sihlbom C, Kretzler M, Betsholtz C, Haraldsson B, Ju W, Ebefors K, Nyström J.

J Am Soc Nephrol. 2017 Oct;28(10):2961-2972. doi: 10.1681/ASN.2016101103. Epub 2017 Jun 23.

44.

Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology.

Barisoni L, Gimpel C, Kain R, Laurinavicius A, Bueno G, Zeng C, Liu Z, Schaefer F, Kretzler M, Holzman LB, Hewitt SM.

Clin Kidney J. 2017 Apr;10(2):176-187. doi: 10.1093/ckj/sfw129. Epub 2017 Feb 18.

45.

Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice.

Zhang H, Nair V, Saha J, Atkins KB, Hodgin JB, Saunders TL, Myers MG Jr, Werner T, Kretzler M, Brosius FC.

Kidney Int. 2017 Oct;92(4):909-921. doi: 10.1016/j.kint.2017.03.027. Epub 2017 May 26.

46.

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy.

Levin A, Tonelli M, Bonventre J, Coresh J, Donner JA, Fogo AB, Fox CS, Gansevoort RT, Heerspink HJL, Jardine M, Kasiske B, Köttgen A, Kretzler M, Levey AS, Luyckx VA, Mehta R, Moe O, Obrador G, Pannu N, Parikh CR, Perkovic V, Pollock C, Stenvinkel P, Tuttle KR, Wheeler DC, Eckardt KU; ISN Global Kidney Health Summit participants.

Lancet. 2017 Oct 21;390(10105):1888-1917. doi: 10.1016/S0140-6736(17)30788-2. Epub 2017 Apr 20. Review.

PMID:
28434650
47.

Erratum to: Evaluating Mendelian nephrotic syndrome genes for evidence for risk alleles or oligogenicity that explain heritability.

Crawford BD, Gillies CE, Robertson CC, Kretzler M, Otto EA, Vega-Warner V, Sampson MG.

Pediatr Nephrol. 2017 Jul;32(7):1285. doi: 10.1007/s00467-017-3653-0. No abstract available.

PMID:
28349212
48.

A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.

Skorecki KL, Lee JH, Langefeld CD, Rosset S, Tzur S, Wasser WG, Shemer R, Hawkins GA, Divers J, Parekh RS, Li M, Sampson MG, Kretzler M, Pollak MR, Shah S, Blackler D, Nichols B, Wilmot M, Alper SL, Freedman BI, Friedman DJ.

Nephrol Dial Transplant. 2018 Feb 1;33(2):323-330. doi: 10.1093/ndt/gfw451.

49.

Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies.

Mariani LH, Martini S, Barisoni L, Canetta PA, Troost JP, Hodgin JB, Palmer M, Rosenberg AZ, Lemley KV, Chien HP, Zee J, Smith A, Appel GB, Trachtman H, Hewitt SM, Kretzler M, Bagnasco SM.

Nephrol Dial Transplant. 2018 Feb 1;33(2):310-318. doi: 10.1093/ndt/gfw443.

50.

Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease.

Hinder LM, Park M, Rumora AE, Hur J, Eichinger F, Pennathur S, Kretzler M, Brosius FC 3rd, Feldman EL.

J Cell Mol Med. 2017 Sep;21(9):2140-2152. doi: 10.1111/jcmm.13136. Epub 2017 Mar 8.

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