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Items: 10

1.

Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma.

Yi Z, Prinzing BL, Cao F, Gottschalk S, Krenciute G.

Mol Ther Methods Clin Dev. 2018 Feb 2;9:70-80. doi: 10.1016/j.omtm.2018.01.009. eCollection 2018 Jun 15.

2.

CAR T-cell therapy for glioblastoma: ready for the next round of clinical testing?

Prinzing BL, Gottschalk SM, Krenciute G.

Expert Rev Anticancer Ther. 2018 May;18(5):451-461. doi: 10.1080/14737140.2018.1451749. Epub 2018 Mar 16.

PMID:
29533108
3.

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma.

Pituch KC, Miska J, Krenciute G, Panek WK, Li G, Rodriguez-Cruz T, Wu M, Han Y, Lesniak MS, Gottschalk S, Balyasnikova IV.

Mol Ther. 2018 Apr 4;26(4):986-995. doi: 10.1016/j.ymthe.2018.02.001. Epub 2018 Feb 8.

PMID:
29503195
4.

Reversible Transgene Expression Reduces Fratricide and Permits 4-1BB Costimulation of CAR T Cells Directed to T-cell Malignancies.

Mamonkin M, Mukherjee M, Srinivasan M, Sharma S, Gomes-Silva D, Mo F, Krenciute G, Orange JS, Brenner MK.

Cancer Immunol Res. 2018 Jan;6(1):47-58. doi: 10.1158/2326-6066.CIR-17-0126. Epub 2017 Oct 27.

5.

Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent.

Gomes-Silva D, Mukherjee M, Srinivasan M, Krenciute G, Dakhova O, Zheng Y, Cabral JMS, Rooney CM, Orange JS, Brenner MK, Mamonkin M.

Cell Rep. 2017 Oct 3;21(1):17-26. doi: 10.1016/j.celrep.2017.09.015.

6.

Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models.

Mata M, Gerken C, Nguyen P, Krenciute G, Spencer DM, Gottschalk S.

Cancer Discov. 2017 Nov;7(11):1306-1319. doi: 10.1158/2159-8290.CD-17-0263. Epub 2017 Aug 11.

PMID:
28801306
7.

Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants.

Krenciute G, Prinzing BL, Yi Z, Wu MF, Liu H, Dotti G, Balyasnikova IV, Gottschalk S.

Cancer Immunol Res. 2017 Jul;5(7):571-581. doi: 10.1158/2326-6066.CIR-16-0376. Epub 2017 May 26.

8.

Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Rα2-positive Glioma.

Krenciute G, Krebs S, Torres D, Wu MF, Liu H, Dotti G, Li XN, Lesniak MS, Balyasnikova IV, Gottschalk S.

Mol Ther. 2016 Feb;24(2):354-363. doi: 10.1038/mt.2015.199. Epub 2015 Oct 30.

9.

Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage signaling and cell death.

Krenciute G, Liu S, Yucer N, Shi Y, Ortiz P, Liu Q, Kim BJ, Odejimi AO, Leng M, Qin J, Wang Y.

J Biol Chem. 2013 Jul 12;288(28):20547-57. doi: 10.1074/jbc.M112.443416. Epub 2013 May 30.

10.

Analysis of the human endogenous coregulator complexome.

Malovannaya A, Lanz RB, Jung SY, Bulynko Y, Le NT, Chan DW, Ding C, Shi Y, Yucer N, Krenciute G, Kim BJ, Li C, Chen R, Li W, Wang Y, O'Malley BW, Qin J.

Cell. 2011 May 27;145(5):787-99. doi: 10.1016/j.cell.2011.05.006.

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