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Items: 1 to 50 of 487

1.

A Drosophila cell-free system that senses DNA breaks and triggers phosphorylation signalling.

Harpprecht L, Baldi S, Schauer T, Schmidt A, Bange T, Robles MS, Kremmer E, Imhof A, Becker PB.

Nucleic Acids Res. 2019 May 31. pii: gkz473. doi: 10.1093/nar/gkz473. [Epub ahead of print]

PMID:
31147711
2.

Kaposi's sarcoma-associated herpesvirus vIRF2 protein utilizes an IFN-dependent pathway to regulate viral early gene expression.

Koch S, Damas M, Freise A, Hage E, Dhingra A, Rückert J, Gallo A, Kremmer E, Tegge W, Brönstrup M, Brune W, Schulz TF.

PLoS Pathog. 2019 May 6;15(5):e1007743. doi: 10.1371/journal.ppat.1007743. eCollection 2019 May.

3.

Pathological ASXL1 Mutations and Protein Variants Impair Neural Crest Development.

Matheus F, Rusha E, Rehimi R, Molitor L, Pertek A, Modic M, Feederle R, Flatley A, Kremmer E, Geerlof A, Rishko V, Rada-Iglesias A, Drukker M.

Stem Cell Reports. 2019 May 14;12(5):861-868. doi: 10.1016/j.stemcr.2019.03.006. Epub 2019 Apr 18.

4.

The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels.

Simons IM, Mohrlüder J, Feederle R, Kremmer E, Zobel T, Dobner J, Bleffert N, Hoffmann S, Willbold D.

Sci Rep. 2019 Jan 24;9(1):526. doi: 10.1038/s41598-018-36717-1.

5.

Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis.

Balta EA, Schäffner I, Wittmann MT, Sock E, von Zweydorf F, von Wittgenstein J, Steib K, Heim B, Kremmer E, Häberle BM, Ueffing M, Lie DC, Gloeckner CJ.

Sci Rep. 2018 Nov 1;8(1):16196. doi: 10.1038/s41598-018-34480-x.

6.

Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to the Transcriptional Outcome of Associated Genes.

Bouchard C, Sahu P, Meixner M, Nötzold RR, Rust MB, Kremmer E, Feederle R, Hart-Smith G, Finkernagel F, Bartkuhn M, Savai Pullamsetti S, Nist A, Stiewe T, Philipsen S, Bauer UM.

Cell Rep. 2018 Sep 18;24(12):3339-3352. doi: 10.1016/j.celrep.2018.08.052.

7.

Interaction of septin 7 and DOCK8 in equine lymphocytes reveals novel insights into signaling pathways associated with autoimmunity.

Schauer M, Kleinwort KJH, Degroote RL, Wiedemann C, Kremmer E, Hauck SM, Deeg CA.

Sci Rep. 2018 Aug 17;8(1):12332. doi: 10.1038/s41598-018-30753-7.

8.

The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy.

Moschovakis GL, Bubke A, Friedrichsen M, Ristenpart J, Back JW, Falk CS, Kremmer E, Förster R.

Cell Mol Immunol. 2018 Jul 4. doi: 10.1038/s41423-018-0056-5. [Epub ahead of print]

PMID:
29973648
9.

Tumor-associated macrophages in human breast cancer produce new monocyte attracting and pro-angiogenic factor YKL-39 indicative for increased metastasis after neoadjuvant chemotherapy.

Liu T, Larionova I, Litviakov N, Riabov V, Zavyalova M, Tsyganov M, Buldakov M, Song B, Moganti K, Kazantseva P, Slonimskaya E, Kremmer E, Flatley A, Klüter H, Cherdyntseva N, Kzhyshkowska J.

Oncoimmunology. 2018 Mar 13;7(6):e1436922. doi: 10.1080/2162402X.2018.1436922. eCollection 2018.

10.

Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy.

Wang C, Edilova MI, Wagar LE, Mujib S, Singer M, Bernard NF, Croughs T, Lederman MM, Sereti I, Fischl MA, Kremmer E, Ostrowski M, Routy JP, Watts TH.

J Immunol. 2018 Jan 15;200(2):558-564. doi: 10.4049/jimmunol.1601254. Epub 2017 Dec 8.

11.

IL-4 driven transcription factor FoxQ1 is expressed by monocytes in atopic dermatitis and stimulates monocyte migration.

Ovsiy I, Riabov V, Manousaridis I, Michel J, Moganti K, Yin S, Liu T, Sticht C, Kremmer E, Harmsen MC, Goerdt S, Gratchev A, Kzhyshkowska J.

Sci Rep. 2017 Dec 4;7(1):16847. doi: 10.1038/s41598-017-17307-z.

12.

Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.

von Ungern-Sternberg SNI, Vogel S, Walker-Allgaier B, Geue S, Maurer A, Wild AM, Münzer P, Chatterjee M, Heinzmann D, Kremmer E, Borst O, Loughran P, Zernecke A, Neal MD, Billiar TR, Gawaz M, Seizer P.

Thromb Haemost. 2017 Nov;117(11):2063-2078. doi: 10.1160/TH17-01-0067. Epub 2017 Nov 30.

13.

Biological function of Dictyocaulus viviparus asparaginyl peptidase legumain-1 and its suitability as a vaccine target.

Holzhausen J, Haake C, Schicht S, Hinse P, Jordan D, Kremmer E, Strube C.

Parasitology. 2018 Mar;145(3):378-392. doi: 10.1017/S0031182017001573. Epub 2017 Sep 25.

PMID:
28942744
14.

Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.

Ayoubian H, Fröhlich T, Pogodski D, Flatley A, Kremmer E, Schepers A, Feederle R, Arnold GJ, Grässer FA.

J Gen Virol. 2017 Aug;98(8):2128-2142. doi: 10.1099/jgv.0.000870. Epub 2017 Jul 28.

PMID:
28758620
15.

The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions.

Carrion MDP, Marsicano S, Daniele F, Marte A, Pischedda F, Di Cairano E, Piovesana E, von Zweydorf F, Kremmer E, Gloeckner CJ, Onofri F, Perego C, Piccoli G.

Sci Rep. 2017 Jul 14;7(1):5377. doi: 10.1038/s41598-017-05760-9.

16.

Development of Novel Monoclonal Antibodies for Evaluation of Transmembrane Prostate Androgen-Induced Protein 1 (TMEPAI) Expression Patterns in Gastric Cancer.

Karbyshev MS, Grigoryeva ES, Volkomorov VV, Kremmer E, Huber A, Mitrofanova IV, Kaigorodova EV, Zavyalova MV, Kzhyshkowska JG, Cherdyntseva NV, Choynzonov EL.

Pathol Oncol Res. 2018 Apr;24(2):427-438. doi: 10.1007/s12253-017-0247-x. Epub 2017 Jun 5.

PMID:
28584893
17.

Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition.

Wagner G, Singhal N, Nicetto D, Straub T, Kremmer E, Rupp RAW.

PLoS Genet. 2017 May 12;13(5):e1006757. doi: 10.1371/journal.pgen.1006757. eCollection 2017 May.

18.

Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD.

Lehmer C, Oeckl P, Weishaupt JH, Volk AE, Diehl-Schmid J, Schroeter ML, Lauer M, Kornhuber J, Levin J, Fassbender K, Landwehrmeyer B; German Consortium for Frontotemporal Lobar Degeneration, Schludi MH, Arzberger T, Kremmer E, Flatley A, Feederle R, Steinacker P, Weydt P, Ludolph AC, Edbauer D, Otto M.

EMBO Mol Med. 2017 Jul;9(7):859-868. doi: 10.15252/emmm.201607486.

19.

Multiepitope tissue analysis reveals SPPL3-mediated ADAM10 activation as a key step in the transformation of melanocytes.

Ostalecki C, Lee JH, Dindorf J, Collenburg L, Schierer S, Simon B, Schliep S, Kremmer E, Schuler G, Baur AS.

Sci Signal. 2017 Mar 14;10(470). pii: eaai8288. doi: 10.1126/scisignal.aai8288.

PMID:
28292959
20.

Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity.

Naschberger E, Geißdörfer W, Bogdan C, Tripal P, Kremmer E, Stürzl M, Britzen-Laurent N.

J Cell Mol Med. 2017 Sep;21(9):1954-1966. doi: 10.1111/jcmm.13116. Epub 2017 Mar 8.

21.

CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.

Weidemann M, Schuster-Gossler K, Stauber M, Wrede C, Hegermann J, Ott T, Boldt K, Beyer T, Serth K, Kremmer E, Blum M, Ueffing M, Gossler A.

Development. 2016 Dec 15;143(24):4736-4748.

22.

The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease.

Abdul-Sater AA, Edilova MI, Clouthier DL, Mbanwi A, Kremmer E, Watts TH.

Nat Immunol. 2017 Jan;18(1):26-35. doi: 10.1038/ni.3618. Epub 2016 Nov 28.

PMID:
27893701
23.

Generation of Pax1/PAX1-Specific Monoclonal Antibodies.

Feederle R, Gerber JK, Middleton A, Northrup E, Kist R, Kremmer E, Peters H.

Monoclon Antib Immunodiagn Immunother. 2016 Oct;35(5):259-262. Epub 2016 Oct 5.

PMID:
27705080
24.

Biochemical and cellular characterization of transcription factors binding to the hyperconserved core promoter-associated M4 motif.

Trung NT, Kremmer E, Mittler G.

BMC Genomics. 2016 Aug 30;17:693. doi: 10.1186/s12864-016-3033-3.

25.

Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells.

Ott CA, Linck L, Kremmer E, Meister G, Bosserhoff AK.

Oncotarget. 2016 Sep 20;7(38):62292-62304. doi: 10.18632/oncotarget.11410.

26.

Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies.

Höfling C, Morawski M, Zeitschel U, Zanier ER, Moschke K, Serdaroglu A, Canneva F, von Hörsten S, De Simoni MG, Forloni G, Jäger C, Kremmer E, Roßner S, Lichtenthaler SF, Kuhn PH.

Aging Cell. 2016 Oct;15(5):953-63. doi: 10.1111/acel.12508. Epub 2016 Jul 29.

27.

Expression and Distribution Pattern of Aquaporin 4, 5 and 11 in Retinas of 15 Different Species.

Amann B, Kleinwort KJ, Hirmer S, Sekundo W, Kremmer E, Hauck SM, Deeg CA.

Int J Mol Sci. 2016 Jul 16;17(7). pii: E1145. doi: 10.3390/ijms17071145.

28.

Methanobactin reverses acute liver failure in a rat model of Wilson disease.

Lichtmannegger J, Leitzinger C, Wimmer R, Schmitt S, Schulz S, Kabiri Y, Eberhagen C, Rieder T, Janik D, Neff F, Straub BK, Schirmacher P, DiSpirito AA, Bandow N, Baral BS, Flatley A, Kremmer E, Denk G, Reiter FP, Hohenester S, Eckardt-Schupp F, Dencher NA, Adamski J, Sauer V, Niemietz C, Schmidt HH, Merle U, Gotthardt DN, Kroemer G, Weiss KH, Zischka H.

J Clin Invest. 2016 Jul 1;126(7):2721-35. doi: 10.1172/JCI85226. Epub 2016 Jun 20.

29.

Specific threonine-4 phosphorylation and function of RNA polymerase II CTD during M phase progression.

Hintermair C, Voß K, Forné I, Heidemann M, Flatley A, Kremmer E, Imhof A, Eick D.

Sci Rep. 2016 Jun 6;6:27401. doi: 10.1038/srep27401.

30.

HIPK family kinases bind and regulate the function of the CCR4-NOT complex.

Rodriguez-Gil A, Ritter O, Hornung J, Stekman H, Krüger M, Braun T, Kremmer E, Kracht M, Schmitz ML.

Mol Biol Cell. 2016 Jun 15;27(12):1969-80. doi: 10.1091/mbc.E15-09-0629. Epub 2016 Apr 27.

31.

Aquaporin 11, a regulator of water efflux at retinal Müller glial cell surface decreases concomitant with immune-mediated gliosis.

Deeg CA, Amann B, Lutz K, Hirmer S, Lutterberg K, Kremmer E, Hauck SM.

J Neuroinflammation. 2016 Apr 23;13(1):89. doi: 10.1186/s12974-016-0554-2.

32.

Generation and deposition of Aβ43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.

Kretner B, Trambauer J, Fukumori A, Mielke J, Kuhn PH, Kremmer E, Giese A, Lichtenthaler SF, Haass C, Arzberger T, Steiner H.

EMBO Mol Med. 2016 May 2;8(5):458-65. doi: 10.15252/emmm.201505952. Print 2016 May.

33.

PARP activation promotes nuclear AID accumulation in lymphoma cells.

Tepper S, Jeschke J, Böttcher K, Schmidt A, Davari K, Müller P, Kremmer E, Hemmerich P, Pfeil I, Jungnickel B.

Oncotarget. 2016 Mar 15;7(11):13197-208. doi: 10.18632/oncotarget.7603.

34.

Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.

Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, Lickert H.

PLoS One. 2016 Feb 22;11(2):e0149477. doi: 10.1371/journal.pone.0149477. eCollection 2016.

35.

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.

Suárez-Calvet M, Neumann M, Arzberger T, Abou-Ajram C, Funk E, Hartmann H, Edbauer D, Kremmer E, Göbl C, Resch M, Bourgeois B, Madl T, Reber S, Jutzi D, Ruepp MD, Mackenzie IR, Ansorge O, Dormann D, Haass C.

Acta Neuropathol. 2016 Apr;131(4):587-604. doi: 10.1007/s00401-016-1544-2. Epub 2016 Feb 19.

PMID:
26895297
36.

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function.

Kuhn PH, Colombo AV, Schusser B, Dreymueller D, Wetzel S, Schepers U, Herber J, Ludwig A, Kremmer E, Montag D, Müller U, Schweizer M, Saftig P, Bräse S, Lichtenthaler SF.

Elife. 2016 Jan 23;5. pii: e12748. doi: 10.7554/eLife.12748.

37.

A TonB-Dependent Transporter Is Responsible for Methanobactin Uptake by Methylosinus trichosporium OB3b.

Gu W, Farhan Ul Haque M, Baral BS, Turpin EA, Bandow NL, Kremmer E, Flatley A, Zischka H, DiSpirito AA, Semrau JD.

Appl Environ Microbiol. 2016 Jan 15;82(6):1917-1923. doi: 10.1128/AEM.03884-15.

38.

The Establishment of a Hyperactive Structure Allows the Tumour Suppressor Protein p53 to Function through P-TEFb during Limited CDK9 Kinase Inhibition.

Albert TK, Antrecht C, Kremmer E, Meisterernst M.

PLoS One. 2016 Jan 8;11(1):e0146648. doi: 10.1371/journal.pone.0146648. eCollection 2016.

39.

Pillars Article: CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs. Cell. 1999. 99: 23-33.

Förster R, Schubel A, Breitfeld D, Kremmer E, Renner-Müller I, Wolf E, Lipp M.

J Immunol. 2016 Jan 1;196(1):5-15. No abstract available.

40.

A K(+)-selective CNG channel orchestrates Ca(2+) signalling in zebrafish sperm.

Fechner S, Alvarez L, Bönigk W, Müller A, Berger TK, Pascal R, Trötschel C, Poetsch A, Stölting G, Siegfried KR, Kremmer E, Seifert R, Kaupp UB.

Elife. 2015 Dec 9;4. pii: e07624. doi: 10.7554/eLife.07624.

41.

Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.

Fleck D, Voss M, Brankatschk B, Giudici C, Hampel H, Schwenk B, Edbauer D, Fukumori A, Steiner H, Kremmer E, Haug-Kröper M, Rossner MJ, Fluhrer R, Willem M, Haass C.

J Biol Chem. 2016 Jan 1;291(1):318-33. doi: 10.1074/jbc.M115.697995. Epub 2015 Nov 16.

42.

Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II.

Voss K, Forné I, Descostes N, Hintermair C, Schüller R, Maqbool MA, Heidemann M, Flatley A, Imhof A, Gut M, Gut I, Kremmer E, Andrau JC, Eick D.

Transcription. 2015;6(5):91-101. doi: 10.1080/21541264.2015.1114983.

43.

Vaccination of calves with yeast- and bacterial-expressed paramyosin from the bovine lungworm Dictyocaulus viviparus.

Joekel D, Hinse P, Raulf MK, Schicht S, Bäumer W, Werling D, Kremmer E, Strube C.

Parasite Immunol. 2015 Dec;37(12):614-23. doi: 10.1111/pim.12280.

44.

Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers.

Mackenzie IR, Frick P, Grässer FA, Gendron TF, Petrucelli L, Cashman NR, Edbauer D, Kremmer E, Prudlo J, Troost D, Neumann M.

Acta Neuropathol. 2015 Dec;130(6):845-61. doi: 10.1007/s00401-015-1476-2. Epub 2015 Sep 15.

PMID:
26374446
45.

η-Secretase processing of APP inhibits neuronal activity in the hippocampus.

Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, Müller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H, Haass C.

Nature. 2015 Oct 15;526(7573):443-7. doi: 10.1038/nature14864. Epub 2015 Aug 31.

46.

Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells.

Gramolelli S, Weidner-Glunde M, Abere B, Viejo-Borbolla A, Bala K, Rückert J, Kremmer E, Schulz TF.

PLoS Pathog. 2015 Aug 21;11(8):e1005105. doi: 10.1371/journal.ppat.1005105. eCollection 2015 Aug.

47.

Erratum to: Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.

Schludi MH, May S, Grässer FA, Rentzsch K, Kremmer E, Küpper C, Klopstock T; German Consortium for Frontotemporal Lobar Degeneration; Bavarian Brain Banking Alliance, Arzberger T, Edbauer D.

Acta Neuropathol. 2015 Oct;130(4):557-8. doi: 10.1007/s00401-015-1464-6.

48.

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation.

Lagouge M, Mourier A, Lee HJ, Spåhr H, Wai T, Kukat C, Silva Ramos E, Motori E, Busch JD, Siira S; German Mouse Clinic Consortium, Kremmer E, Filipovska A, Larsson NG.

PLoS Genet. 2015 Aug 6;11(8):e1005423. doi: 10.1371/journal.pgen.1005423. eCollection 2015 Aug.

49.

Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels.

Schraivogel D, Schindler SG, Danner J, Kremmer E, Pfaff J, Hannus S, Depping R, Meister G.

Nucleic Acids Res. 2015 Sep 3;43(15):7447-61. doi: 10.1093/nar/gkv705. Epub 2015 Jul 13.

50.

Interferon Gamma Counteracts the Angiogenic Switch and Induces Vascular Permeability in Dextran Sulfate Sodium Colitis in Mice.

Haep L, Britzen-Laurent N, Weber TG, Naschberger E, Schaefer A, Kremmer E, Foersch S, Vieth M, Scheuer W, Wirtz S, Waldner M, Stürzl M.

Inflamm Bowel Dis. 2015 Oct;21(10):2360-71. doi: 10.1097/MIB.0000000000000490.

PMID:
26164664

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