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Items: 1 to 50 of 57

1.

The Nebulin Family LIM and SH3 Proteins Regulate Postsynaptic Development and Function.

Myers KR, Yu K, Kremerskothen J, Butt E, Zheng JQ.

J Neurosci. 2020 Jan 15;40(3):526-541. doi: 10.1523/JNEUROSCI.0334-19.2019. Epub 2019 Nov 21.

PMID:
31754010
2.

Intrinsic disorder and amino acid specificity modulate binding of the WW2 domain in kidney and brain protein (KIBRA) to synaptopodin.

Kwok E, Rodriguez DJ, Kremerskothen J, Nyarko A.

J Biol Chem. 2019 Nov 15;294(46):17383-17394. doi: 10.1074/jbc.RA119.009589. Epub 2019 Oct 9.

PMID:
31597702
3.

FRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells.

Rong X, Han Q, Lin X, Kremerskothen J, Wang E.

Cancer Manag Res. 2019 Apr 18;11:3395-3410. doi: 10.2147/CMAR.S194512. eCollection 2019.

4.

Nuclear YAP localization as a key regulator of podocyte function.

Bonse J, Wennmann DO, Kremerskothen J, Weide T, Michgehl U, Pavenstädt H, Vollenbröker B.

Cell Death Dis. 2018 Aug 28;9(9):850. doi: 10.1038/s41419-018-0878-1.

5.

Getting a Notch closer to renal dysfunction: activated Notch suppresses expression of the adaptor protein Disabled-2 in tubular epithelial cells.

Schütte-Nütgen K, Edeling M, Mendl G, Krahn MP, Edemir B, Weide T, Kremerskothen J, Michgehl U, Pavenstädt H.

FASEB J. 2019 Jan;33(1):821-832. doi: 10.1096/fj.201800392RR. Epub 2018 Jul 27.

PMID:
30052485
6.

WWC3 inhibits epithelial-mesenchymal transition of lung cancer by activating Hippo-YAP signaling.

Han Q, Kremerskothen J, Lin X, Zhang X, Rong X, Zhang D, Wang E.

Onco Targets Ther. 2018 May 8;11:2581-2591. doi: 10.2147/OTT.S162387. eCollection 2018.

7.

Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.

Posner MG, Upadhyay A, Ishima R, Kalli AC, Harris G, Kremerskothen J, Sansom MSP, Crennell SJ, Bagby S.

J Biol Chem. 2018 Jun 15;293(24):9335-9344. doi: 10.1074/jbc.RA118.002279. Epub 2018 May 3.

8.

WW and C2 domain-containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway.

Hermann A, Wennmann DO, Gromnitza S, Edeling M, Van Marck V, Sudol M, Schaefer L, Duning K, Weide T, Pavenstädt H, Kremerskothen J.

Hepatology. 2018 Apr;67(4):1546-1559. doi: 10.1002/hep.29647. Epub 2018 Feb 18.

PMID:
29116649
9.

WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma.

Zhang Y, Yan S, Chen J, Gan C, Chen D, Li Y, Wen J, Kremerskothen J, Chen S, Zhang J, Cao Y.

J Cell Mol Med. 2017 Dec;21(12):3718-3729. doi: 10.1111/jcmm.13281. Epub 2017 Aug 16.

10.

KIBRA attains oncogenic activity by repressing RASSF1A.

Anuj, Arivazhagan L, Surabhi RP, Kanakarajan A, Sundaram S, Pitani RS, Mudduwa L, Kremerskothen J, Venkatraman G, Rayala SK.

Br J Cancer. 2017 Jun 29. doi: 10.1038/bjc.2017.192. [Epub ahead of print]

11.

WWC3 regulates the Wnt and Hippo pathways via Dishevelled proteins and large tumour suppressor 1, to suppress lung cancer invasion and metastasis.

Han Q, Lin X, Zhang X, Jiang G, Zhang Y, Miao Y, Rong X, Zheng X, Han Y, Han X, Wu J, Kremerskothen J, Wang E.

J Pathol. 2017 Aug;242(4):435-447. doi: 10.1002/path.4919. Epub 2017 Jun 29.

PMID:
28543074
12.

Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells.

Mavuluri J, Beesetti S, Surabhi R, Kremerskothen J, Venkatraman G, Rayala SK.

Mol Cell Biol. 2016 Apr 15;36(9):1354-65. doi: 10.1128/MCB.01004-15. Print 2016 May.

13.

The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes.

Wennmann DO, Vollenbröker B, Eckart AK, Bonse J, Erdmann F, Wolters DA, Schenk LK, Schulze U, Kremerskothen J, Weide T, Pavenstädt H.

Cell Death Dis. 2014 Nov 13;5:e1519. doi: 10.1038/cddis.2014.476.

14.

Evolutionary and molecular facts link the WWC protein family to Hippo signaling.

Wennmann DO, Schmitz J, Wehr MC, Krahn MP, Koschmal N, Gromnitza S, Schulze U, Weide T, Chekuri A, Skryabin BV, Gerke V, Pavenstädt H, Duning K, Kremerskothen J.

Mol Biol Evol. 2014 Jul;31(7):1710-23. doi: 10.1093/molbev/msu115. Epub 2014 Mar 27.

PMID:
24682284
15.

KIBRA: In the brain and beyond.

Zhang L, Yang S, Wennmann DO, Chen Y, Kremerskothen J, Dong J.

Cell Signal. 2014 Jul;26(7):1392-9. doi: 10.1016/j.cellsig.2014.02.023. Epub 2014 Mar 15.

16.

The Vac14-interaction network is linked to regulators of the endolysosomal and autophagic pathway.

Schulze U, Vollenbröker B, Braun DA, Van Le T, Granado D, Kremerskothen J, Fränzel B, Klosowski R, Barth J, Fufezan C, Wolters DA, Pavenstädt H, Weide T.

Mol Cell Proteomics. 2014 Jun;13(6):1397-411. doi: 10.1074/mcp.M113.034108. Epub 2014 Feb 27.

17.

Expression of synaptopodin in endothelial cells exposed to laminar shear stress and its role in endothelial wound healing.

Mun GI, Park S, Kremerskothen J, Boo YC.

FEBS Lett. 2014 Mar 18;588(6):1024-30. doi: 10.1016/j.febslet.2014.02.012. Epub 2014 Feb 20.

18.

Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration.

Yang S, Ji M, Zhang L, Chen Y, Wennmann DO, Kremerskothen J, Dong J.

Cell Signal. 2014 Feb;26(2):343-51. doi: 10.1016/j.cellsig.2013.11.012. Epub 2013 Nov 19.

19.

KIBRA (KIdney/BRAin protein) regulates learning and memory and stabilizes Protein kinase Mζ.

Vogt-Eisele A, Krüger C, Duning K, Weber D, Spoelgen R, Pitzer C, Plaas C, Eisenhardt G, Meyer A, Vogt G, Krieger M, Handwerker E, Wennmann DO, Weide T, Skryabin BV, Klugmann M, Pavenstädt H, Huentelmann MJ, Kremerskothen J, Schneider A.

J Neurochem. 2014 Mar;128(5):686-700. doi: 10.1111/jnc.12480. Epub 2013 Oct 28.

20.

Tissue-specific differences in the regulation of KIBRA gene expression involve transcription factor TCF7L2 and a complex alternative promoter system.

Guske K, Schmitz B, Schelleckes M, Duning K, Kremerskothen J, Pavenstädt HJ, Brand SM, Brand E.

J Mol Med (Berl). 2014 Feb;92(2):185-96. doi: 10.1007/s00109-013-1089-y. Epub 2013 Sep 27.

PMID:
24072042
21.

Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance.

Duning K, Wennmann DO, Bokemeyer A, Reissner C, Wersching H, Thomas C, Buschert J, Guske K, Franzke V, Flöel A, Lohmann H, Knecht S, Brand SM, Pöter M, Rescher U, Missler M, Seelheim P, Pröpper C, Boeckers TM, Makuch L, Huganir R, Weide T, Brand E, Pavenstädt H, Kremerskothen J.

Transl Psychiatry. 2013 Jun 18;3:e272. doi: 10.1038/tp.2013.49.

22.

Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions.

Mihlan S, Reiß C, Thalheimer P, Herterich S, Gaetzner S, Kremerskothen J, Pavenstädt HJ, Lewandrowski U, Sickmann A, Butt E.

Oncogene. 2013 Apr 18;32(16):2107-13. doi: 10.1038/onc.2012.216. Epub 2012 Jun 4.

PMID:
22665060
23.

Lasp-1 regulates podosome function.

Stölting M, Wiesner C, van Vliet V, Butt E, Pavenstädt H, Linder S, Kremerskothen J.

PLoS One. 2012;7(4):e35340. doi: 10.1371/journal.pone.0035340. Epub 2012 Apr 13.

24.

Topoisomerase IIβ associates with Ku70 and PARP-1 during double strand break repair of DNA in neurons.

Mandraju R, Chekuri A, Bhaskar C, Duning K, Kremerskothen J, Kondapi AK.

Arch Biochem Biophys. 2011 Dec 15;516(2):128-37. doi: 10.1016/j.abb.2011.09.017. Epub 2011 Oct 10.

PMID:
22019940
25.

Regulation of AMPA receptor function by the human memory-associated gene KIBRA.

Makuch L, Volk L, Anggono V, Johnson RC, Yu Y, Duning K, Kremerskothen J, Xia J, Takamiya K, Huganir RL.

Neuron. 2011 Sep 22;71(6):1022-9. doi: 10.1016/j.neuron.2011.08.017. Epub 2011 Sep 21.

26.

Conformational dynamics promote binding diversity of dynein light chain LC8.

Nyarko A, Hall J, Hall A, Hare M, Kremerskothen J, Barbar E.

Biophys Chem. 2011 Nov;159(1):41-7. doi: 10.1016/j.bpc.2011.05.001. Epub 2011 May 6.

PMID:
21621319
27.

Impact of common KIBRA allele on human cognitive functions.

Wersching H, Guske K, Hasenkamp S, Hagedorn C, Schiwek S, Jansen S, Witte V, Wellmann J, Lohmann H, Duning K, Kremerskothen J, Knecht S, Brand E, Floel A.

Neuropsychopharmacology. 2011 May;36(6):1296-304. doi: 10.1038/npp.2011.16. Epub 2011 Feb 23.

28.

Zona occludens proteins modulate podosome formation and function.

Kremerskothen J, Stölting M, Wiesner C, Korb-Pap A, van Vliet V, Linder S, Huber TB, Rottiers P, Reuzeau E, Genot E, Pavenstädt H.

FASEB J. 2011 Feb;25(2):505-14. doi: 10.1096/fj.10-155598. Epub 2010 Oct 7.

PMID:
20930113
29.

KIBRA: A New Gateway to Learning and Memory?

Schneider A, Huentelman MJ, Kremerskothen J, Duning K, Spoelgen R, Nikolich K.

Front Aging Neurosci. 2010 Feb 12;2:4. doi: 10.3389/neuro.24.004.2010. eCollection 2010.

30.

An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation.

Rosse C, Formstecher E, Boeckeler K, Zhao Y, Kremerskothen J, White MD, Camonis JH, Parker PJ.

PLoS Biol. 2009 Nov;7(11):e1000235. doi: 10.1371/journal.pbio.1000235. Epub 2009 Nov 3.

31.

Temporal-spatial expression and novel biochemical properties of the memory-related protein KIBRA.

Johannsen S, Duning K, Pavenstädt H, Kremerskothen J, Boeckers TM.

Neuroscience. 2008 Sep 9;155(4):1165-73. doi: 10.1016/j.neuroscience.2008.06.054. Epub 2008 Jul 3.

PMID:
18672031
32.

KIBRA modulates directional migration of podocytes.

Duning K, Schurek EM, Schlüter M, Bayer M, Reinhardt HC, Schwab A, Schaefer L, Benzing T, Schermer B, Saleem MA, Huber TB, Bachmann S, Kremerskothen J, Weide T, Pavenstädt H.

J Am Soc Nephrol. 2008 Oct;19(10):1891-903. doi: 10.1681/ASN.2007080916. Epub 2008 Jul 2.

33.

SYNCRIP, a component of dendritically localized mRNPs, binds to the translation regulator BC200 RNA.

Duning K, Buck F, Barnekow A, Kremerskothen J.

J Neurochem. 2008 Apr;105(2):351-9. Epub 2007 Nov 27.

34.

SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment.

Traer CJ, Rutherford AC, Palmer KJ, Wassmer T, Oakley J, Attar N, Carlton JG, Kremerskothen J, Stephens DJ, Cullen PJ.

Nat Cell Biol. 2007 Dec;9(12):1370-80. Epub 2007 Nov 11.

PMID:
17994011
35.

Characterization of KIAA0513, a novel signaling molecule that interacts with modulators of neuroplasticity, apoptosis, and the cytoskeleton.

Lauriat TL, Dracheva S, Kremerskothen J, Duning K, Haroutunian V, Buxbaum JD, Hyde TM, Kleinman JE, McInnes LA.

Brain Res. 2006 Nov 22;1121(1):1-11. Epub 2006 Sep 29.

PMID:
17010949
36.

Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cells.

Rayala SK, den Hollander P, Manavathi B, Talukder AH, Song C, Peng S, Barnekow A, Kremerskothen J, Kumar R.

J Biol Chem. 2006 Jul 14;281(28):19092-9. Epub 2006 May 9.

37.

Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring.

Kremerskothen J, Kindler S, Finger I, Veltel S, Barnekow A.

J Neurochem. 2006 Mar;96(6):1659-66. Epub 2006 Feb 8.

38.

Rab6 interacts with the mint3 adaptor protein.

Teber I, Nagano F, Kremerskothen J, Bilbilis K, Goud B, Barnekow A.

Biol Chem. 2005 Jul;386(7):671-7.

PMID:
16207088
39.

Identification and characterization of Iporin as a novel interaction partner for rab1.

Bayer M, Fischer J, Kremerskothen J, Ossendorf E, Matanis T, Konczal M, Weide T, Barnekow A.

BMC Cell Biol. 2005 Mar 29;6(1):15.

40.

Synaptopodin, a molecule involved in the formation of the dendritic spine apparatus, is a dual actin/alpha-actinin binding protein.

Kremerskothen J, Plaas C, Kindler S, Frotscher M, Barnekow A.

J Neurochem. 2005 Feb;92(3):597-606.

41.

Interaction of rat poly(A)-binding protein with poly(A)- and non-poly(A) sequences is preferentially mediated by RNA recognition motifs 3+4.

Mullin C, Duning K, Barnekow A, Richter D, Kremerskothen J, Mohr E.

FEBS Lett. 2004 Oct 22;576(3):437-41.

42.

KIBRA is a novel substrate for protein kinase Czeta.

Büther K, Plaas C, Barnekow A, Kremerskothen J.

Biochem Biophys Res Commun. 2004 May 7;317(3):703-7.

PMID:
15081397
43.

Muscarinic acetylcholine receptor stimulation induces expression of the activity-regulated cytoskeleton-associated gene (ARC).

Teber I, Köhling R, Speckmann EJ, Barnekow A, Kremerskothen J.

Brain Res Mol Brain Res. 2004 Feb 5;121(1-2):131-6.

PMID:
14969744
44.

Characterization of KIBRA, a novel WW domain-containing protein.

Kremerskothen J, Plaas C, Büther K, Finger I, Veltel S, Matanis T, Liedtke T, Barnekow A.

Biochem Biophys Res Commun. 2003 Jan 24;300(4):862-7.

PMID:
12559952
45.

Poly(A)-binding protein is associated with neuronal BC1 and BC200 ribonucleoprotein particles.

Muddashetty R, Khanam T, Kondrashov A, Bundman M, Iacoangeli A, Kremerskothen J, Duning K, Barnekow A, Hüttenhofer A, Tiedge H, Brosius J.

J Mol Biol. 2002 Aug 16;321(3):433-45.

PMID:
12162957
46.

Brain-specific splicing of alpha-actinin 1 (ACTN1) mRNA.

Kremerskothen J, Teber I, Wendholt D, Liedtke T, Böckers TM, Barnekow A.

Biochem Biophys Res Commun. 2002 Jul 19;295(3):678-81.

PMID:
12099693
48.

Birth of a gene: locus of neuronal BC200 snmRNA in three prosimians and human BC200 pseudogenes as archives of change in the Anthropoidea lineage.

Kuryshev VY, Skryabin BV, Kremerskothen J, Jurka J, Brosius J.

J Mol Biol. 2001 Jun 22;309(5):1049-66. Erratum in: J Mol Biol 2001 Jul 27;310(5):1177-8.

PMID:
11399078
49.

Human activity-regulated cytoskeleton-associated gene (ARC) maps to chromosome 8q24.

Kremerskothen J, Barnekow A.

Chromosome Res. 2000;8(7):655. No abstract available.

PMID:
11117363
50.

Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy.

Haug K, Kremerskothen J, Hallmann K, Sander T, Dullinger J, Rau B, Beyenburg S, Lentze MJ, Barnekow A, Elger CE, Propping P, Heils A.

Mol Cell Probes. 2000 Aug;14(4):255-60.

PMID:
10970730

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