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Items: 1 to 50 of 99

1.

Meta- and pooled analysis of GSTT1 and lung cancer: a HuGE-GSEC review.

Raimondi S, Paracchini V, Autrup H, Barros-Dios JM, Benhamou S, Boffetta P, Cote ML, Dialyna IA, Dolzan V, Filiberti R, Garte S, Hirvonen A, Husgafvel-Pursiainen K, Imyanitov EN, Kalina I, Kang D, Kiyohara C, Kohno T, Kremers P, Lan Q, London S, Povey AC, Rannug A, Reszka E, Risch A, Romkes M, Schneider J, Seow A, Shields PG, Sobti RC, Sørensen M, Spinola M, Spitz MR, Strange RC, Stücker I, Sugimura H, To-Figueras J, Tokudome S, Yang P, Yuan JM, Warholm M, Taioli E.

Am J Epidemiol. 2006 Dec 1;164(11):1027-42. Epub 2006 Sep 25.

PMID:
17000715
2.

CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions.

Vineis P, Veglia F, Anttila S, Benhamou S, Clapper ML, Dolzan V, Ryberg D, Hirvonen A, Kremers P, Le Marchand L, Pastorelli R, Rannug A, Romkes M, Schoket B, Strange RC, Garte S, Taioli E.

Biomarkers. 2004 May-Jun;9(3):298-305.

PMID:
15764294
3.

Molecular approaches to the identification of biomarkers of exposure and effect--report of an expert meeting organized by COST Action B15. November 28, 2003.

Gundert-Remy U, Dahl SG, Boobis A, Kremers P, Kopp-Schneider A, Oberemm A, Renwick A, Pelkonen O.

Toxicol Lett. 2005 Apr 10;156(2):227-40. Epub 2005 Jan 8. Review.

PMID:
15737486
4.

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls.

Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Coutelle C, Daly AK, Muzi G, Dolzan V, Duzhak TG, Farker K, Golka K, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Katoh T, Kihara M, Ono-Kihara M, Kim H, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, London S, Manni JJ, Maugard CM, Morgan GJ, Morita S, Nazar-Stewart V, Kristensen VN, Oda Y, Parl FF, Peters WH, Rannug A, Rebbeck T, Pinto LF, Risch A, Romkes M, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnett D, Strange RC, Stucker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Zheng W, Pedotti P, Taioli E.

Int J Cancer. 2004 Jun 10;110(2):266-70.

5.

Can drug-drug interactions be predicted from in vitro studies?

Kremers P.

ScientificWorldJournal. 2002 Mar 19;2:751-66. Review.

6.

Structure and polymorphisms of human aryl hydrocarbon receptor repressor (AhRR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer.

Cauchi S, Stücker I, Cénée S, Kremers P, Beaune P, Massaad-Massade L.

Pharmacogenetics. 2003 Jun;13(6):339-47.

PMID:
12777964
7.

Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.

Taioli E, Gaspari L, Benhamou S, Boffetta P, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Dolzan V, Haugen A, Hirvonen A, Husgafvel-Pursiainen K, Kalina I, Kremers P, Le Marchand L, London S, Rannug A, Romkes M, Schoket B, Seidegard J, Strange RC, Stucker I, To-Figueras J, Garte S.

Int J Epidemiol. 2003 Feb;32(1):60-3.

PMID:
12690010
8.

CYP1A1 T3801 C polymorphism and lung cancer: a pooled analysis of 2451 cases and 3358 controls.

Vineis P, Veglia F, Benhamou S, Butkiewicz D, Cascorbi I, Clapper ML, Dolzan V, Haugen A, Hirvonen A, Ingelman-Sundberg M, Kihara M, Kiyohara C, Kremers P, Le Marchand L, Ohshima S, Pastorelli R, Rannug A, Romkes M, Schoket B, Shields P, Strange RC, Stucker I, Sugimura H, Garte S, Gaspari L, Taioli E.

Int J Cancer. 2003 May 1;104(5):650-7.

9.

In vitro tests for predicting drug-drug interactions: the need for validated procedures.

Kremers P.

Pharmacol Toxicol. 2002 Nov;91(5):209-17. Review.

PMID:
12570028
10.

In silico prediction of ADME and pharmacokinetics. Report of an expert meeting organised by COST B15.

Boobis A, Gundert-Remy U, Kremers P, Macheras P, Pelkonen O.

Eur J Pharm Sci. 2002 Dec;17(4-5):183-93.

PMID:
12453607
11.

Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk.

Benhamou S, Lee WJ, Alexandrie AK, Boffetta P, Bouchardy C, Butkiewicz D, Brockmöller J, Clapper ML, Daly A, Dolzan V, Ford J, Gaspari L, Haugen A, Hirvonen A, Husgafvel-Pursiainen K, Ingelman-Sundberg M, Kalina I, Kihara M, Kremers P, Le Marchand L, London SJ, Nazar-Stewart V, Onon-Kihara M, Rannug A, Romkes M, Ryberg D, Seidegard J, Shields P, Strange RC, Stücker I, To-Figueras J, Brennan P, Taioli E.

Carcinogenesis. 2002 Aug;23(8):1343-50. Erratum in: Carcinogenesis 2002 Oct;23(10):1771.

PMID:
12151353
12.

Metabolic gene polymorphism frequencies in control populations.

Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, Bouchardy C, Breskvar K, Brockmoller J, Cascorbi I, Clapper ML, Coutelle C, Daly A, Dell'Omo M, Dolzan V, Dresler CM, Fryer A, Haugen A, Hein DW, Hildesheim A, Hirvonen A, Hsieh LL, Ingelman-Sundberg M, Kalina I, Kang D, Kihara M, Kiyohara C, Kremers P, Lazarus P, Le Marchand L, Lechner MC, van Lieshout EM, London S, Manni JJ, Maugard CM, Morita S, Nazar-Stewart V, Noda K, Oda Y, Parl FF, Pastorelli R, Persson I, Peters WH, Rannug A, Rebbeck T, Risch A, Roelandt L, Romkes M, Ryberg D, Salagovic J, Schoket B, Seidegard J, Shields PG, Sim E, Sinnet D, Strange RC, Stücker I, Sugimura H, To-Figueras J, Vineis P, Yu MC, Taioli E.

Cancer Epidemiol Biomarkers Prev. 2001 Dec;10(12):1239-48.

13.

Polymorphisms of human aryl hydrocarbon receptor (AhR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer.

Cauchi S, Stücker I, Solas C, Laurent-Puig P, Cénée S, Hémon D, Jacquet M, Kremers P, Beaune P, Massaad-Massade L.

Carcinogenesis. 2001 Nov;22(11):1819-24.

PMID:
11698344
14.

Protection against nitrofurantoin-induced oxidative stress by coelenterazine analogues and their oxidation products in rat hepatocytes.

Dubuisson ML, De Wergifosse B, Kremers P, Marchand-Brynaert J, Trouet A, Rees JF.

Free Radic Res. 2001 Mar;34(3):285-96.

PMID:
11264902
15.

Relation between inducibility of CYP1A1, GSTM1 and lung cancer in a French population.

Stücker I, Jacquet M, de Waziers I, Cénée S, Beaune P, Kremers P, Hémon D.

Pharmacogenetics. 2000 Oct;10(7):617-27.

PMID:
11037803
16.

Regulation of CYP4A1 and peroxisome proliferator-activated receptor alpha expression by interleukin-1beta, interleukin-6, and dexamethasone in cultured fetal rat hepatocytes.

Parmentier JH, Schohn H, Bronner M, Ferrari L, Batt AM, Dauça M, Kremers P.

Biochem Pharmacol. 1997 Oct 15;54(8):889-98.

PMID:
9354589
17.

Mitogen-activated lymphocytes: a good model for characterising lung CYP1A1 inducibility.

Jacquet M, Lambert V, Todaro A, Kremers P.

Eur J Epidemiol. 1997 Feb;13(2):177-83.

PMID:
9085001
18.
19.

Correlation between P450 CYP1A1 inducibility, MspI genotype and lung cancer incidence.

Jacquet M, Lambert V, Baudoux E, Muller M, Kremers P, Gielen J.

Eur J Cancer. 1996 Sep;32A(10):1701-6.

PMID:
8983277
20.

Hierarchical cluster analysis of environmental pollutants through P450 induction in cultured hepatic cells.

Dubois M, Plaisance H, Thomé JP, Kremers P.

Ecotoxicol Environ Saf. 1996 Aug;34(3):205-15.

PMID:
8812189
21.

Selective induction of the CYP3A family by endosulfan and DNA-adduct formation in different hepatic and hepatoma cells.

Dubois M, Pfohl-Leszkowicz A, De Waziers I, Kremers P.

Environ Toxicol Pharmacol. 1996 Jul 15;1(4):249-56. doi: 10.1016/1382-6689(96)00018-X.

PMID:
21781690
22.

Influence of interleukin-2 regimens on circulating populations of lymphocytes after adoptive transfer of anti-CD3-stimulated T cells: results from a phase I trial in cancer patients.

Curti BD, Ochoa AC, Urba WJ, Alvord WG, Kopp WC, Powers G, Hawk C, Creekmore SP, Gause BL, Janik JE, Holmlund JT, Kremers P, Fenton RG, Miller L, Sznol M, Smith JW 2nd, Sharfman WH, Longo DL.

J Immunother Emphasis Tumor Immunol. 1996 Jul;19(4):296-308.

PMID:
8877723
23.

Ultrastructural modifications in cultured fetal quail hepatocytes exposed to pesticides and PCBs.

Hugla JL, Goffinet G, Kremers P, Dubois M, Lambert V, Stouvenakers N, Thome JP.

Ecotoxicol Environ Saf. 1996 Jul;34(2):145-55.

PMID:
8812180
24.

Effects on PCBs on liver ultrastructure and monooxygenase activities in Japanese quail.

Stouvenakers N, Hugla JL, Goffinet G, Kremers P, Thomé JP.

Bull Environ Contam Toxicol. 1996 May;56(5):839-46. No abstract available.

PMID:
8661870
25.

P450 induction by Aroclor 1254 and 3,3',4,4'-tetrachlorobiphenyl in cultured hepatocytes from rat, quail and man: interspecies comparison.

Dubois M, De Waziers I, Thome JP, Kremers P.

Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996 Jan;113(1):51-9.

PMID:
8665401
26.

DNA adducts and P450 induction in human, rat and avian liver cells after exposure to polychlorobiphenyls.

Dubois M, Pfohl-Leszkowicz A, Grosse Y, Kremers P.

Mutat Res. 1995 Dec;345(3-4):181-90.

PMID:
8552139
27.

Effect of inducers and PCBs on the cytochrome P450 enzymes in cultured quail hepatocytes.

Roelandt L, Dubois M, Todaro A, Thome JP, Kremers P.

Ecotoxicol Environ Saf. 1995 Jul;31(2):158-63.

PMID:
8521782
28.

Effects of PCBs (Aroclor 1254) on cytochrome-P450 expression and monooxygenase activities in cultured foetal rat hepatocytes.

Roelandt L, Todaro A, Thomé JP, Kremers P.

Toxicology. 1995 Apr 12;98(1-3):95-103.

PMID:
7740558
29.

Cytotoxic effects of Aroclor 1254 on ultrastructure and biochemical parameters in cultured foetal rat hepatocytes.

Thomé JP, Roelandt L, Goffinet G, Stouvenakers N, Kremers P.

Toxicology. 1995 Apr 12;98(1-3):83-94.

PMID:
7740557
30.

Expression and induction of drug-metabolizing enzymes in cultured fetal rat hepatocytes.

Kremers P, Roelandt L, Stouvenakers N, Goffinet G, Thome JP.

Cell Biol Toxicol. 1994 Apr;10(2):117-25.

PMID:
7953909
31.

Use of cultured hepatocytes as an alternative method to study the effects of PCBs on living organisms.

Kremers P, Roelandt L, Todaro A, Stouvenakers N, Louvet M, Goffinet G, Thome JP.

Toxicol In Vitro. 1993 Jul;7(4):433-7.

PMID:
20732229
32.

Repression of cytochrome P450 by cytokines: IL-1 beta counteracts clofibric acid induction of CYP4A in cultured fetal rat hepatocytes.

Parmentier JH, Kremers P, Ferrari L, Batt AM, Gielen JE, Siest G.

Cell Biol Toxicol. 1993 Jul-Sep;9(3):307-13.

PMID:
8299008
33.

Induction and characterization of cytochromes P450IA and -IIB in the newt, Pleurodeles waltl.

Marty J, Rivière JL, Guinaudy MJ, Kremers P, Lesca P.

Ecotoxicol Environ Saf. 1992 Oct;24(2):144-54.

PMID:
1280580
34.

Expression of drug-metabolizing enzymes and P-170 glycoprotein in colorectal carcinoma and normal mucosa.

Peters WH, Boon CE, Roelofs HM, Wobbes T, Nagengast FM, Kremers PG.

Gastroenterology. 1992 Aug;103(2):448-55.

PMID:
1353041
35.

The effect of age on inducibility of various types of rat liver cytochrome P-450.

Horbach GJ, Van Asten JG, Rietjens IM, Kremers P, Van Bezooijen CF.

Xenobiotica. 1992 May;22(5):515-22.

PMID:
1413866
36.

Differential effects of human recombinant interleukin-1 beta on cytochrome P-450-dependent activities in cultured fetal rat hepatocytes.

Ferrari L, Kremers P, Batt AM, Gielen JE, Siest G.

Drug Metab Dispos. 1992 May-Jun;20(3):407-12.

PMID:
1355716
37.

Biotransformation enzymes in human intestine: critical low levels in the colon?

Peters WH, Kock L, Nagengast FM, Kremers PG.

Gut. 1991 Apr;32(4):408-12.

38.
39.

Effects of age and gender on in vitro properties of human liver microsomal monooxygenases.

Schmucker DL, Woodhouse KW, Wang RK, Wynne H, James OF, McManus M, Kremers P.

Clin Pharmacol Ther. 1990 Oct;48(4):365-74.

PMID:
2121408
40.

Self-contained, coaxial delivery system for intraarterial infusion of thrombolytic agents.

Matsumoto AH, Barth KH, Teitelbaum GP, Kremers PW.

Radiology. 1990 Mar;174(3 Pt 2):1056-7.

PMID:
2305091
41.

Quantitative digital subtraction arteriography with a calibration catheter.

Barth KH, Kremers PW, Lindisch D, Wang P, Mertens MA.

Cardiovasc Intervent Radiol. 1989 Sep-Oct;12(5):281-5.

PMID:
2514991
42.

Induction of liver microsomal cytochrome P-450 isozymes by 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline carboxamide.

Totis M, Kremers P, Batt AM, Van Cantfort J, Siest G, Gielen J.

Xenobiotica. 1989 Aug;19(8):857-66.

PMID:
2815828
43.

Adrenal insufficiency and interleukin-2 therapy.

VanderMolen LA, Smith JW 2nd, Longo DL, Steis RG, Kremers P, Sznol M.

Ann Intern Med. 1989 Jul 15;111(2):185. No abstract available.

PMID:
2787137
44.

Cytochromes P-450 in the intestinal mucosa of man.

Peters WH, Kremers PG.

Biochem Pharmacol. 1989 May 1;38(9):1535-8.

PMID:
2719725
45.

Mixing problems of low flow hepatic artery infusion. Improvement with small caliber double lumen balloon catheters.

Barth KH, Lutz RJ, Kremers PW, Miller DL.

Invest Radiol. 1988 Jul;23(7):519-23.

PMID:
3170140
46.

Percutaneous balloon dilatation in treatment of infected pyelocaliceal diverticulum.

Kremers PW, Beckmann CF, Bihrle W 3rd.

Urology. 1988 Jul;32(1):29-32.

PMID:
3133865
47.

Ultrasound guided percutaneous cholecystocholangiography for early differentiation of cholestatic liver disease in infants.

Treem WR, Grant EE, Barth KH, Kremers PW.

J Pediatr Gastroenterol Nutr. 1988 May-Jun;7(3):347-52.

PMID:
3290418
48.

Long-term maintenance of monoxygenase activities in cultured fetal rat hepatocytes.

Bollinne A, Kremers P, Kolodzici C, Gielen JE.

Cell Differ. 1987 Sep;21(4):239-46.

PMID:
3497725
49.

Immunochemical evidence for multiple steroid-inducible hepatic cytochromes P-450 in the rat.

Hostetler KA, Wrighton SA, Kremers P, Guzelian PS.

Biochem J. 1987 Jul 1;245(1):27-33.

50.

Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver.

Molowa DT, Schuetz EG, Wrighton SA, Watkins PB, Kremers P, Mendez-Picon G, Parker GA, Guzelian PS.

Proc Natl Acad Sci U S A. 1986 Jul;83(14):5311-5.

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