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Items: 1 to 50 of 181

1.

Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons.

Bayó-Puxan N, Terrasso AP, Creyssels S, Simão D, Begon-Pescia C, Lavigne M, Salinas S, Bernex F, Bosch A, Kalatzis V, Levade T, Cuervo AM, Lory P, Consiglio A, Brito C, Kremer EJ.

Sci Rep. 2018 Nov 9;8(1):16644. doi: 10.1038/s41598-018-34523-3.

2.

Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis.

Jawaid A, Woldemichael BT, Kremer EA, Laferriere F, Gaur N, Afroz T, Polymenidou M, Mansuy IM.

Mol Neurobiol. 2018 Aug 20. doi: 10.1007/s12035-018-1314-3. [Epub ahead of print]

PMID:
30128653
3.

Humoral immune response to adenovirus induce tolerogenic bystander dendritic cells that promote generation of regulatory T cells.

Tran TTP, Eichholz K, Amelio P, Moyer C, Nemerow GR, Perreau M, Mennechet FJD, Kremer EJ.

PLoS Pathog. 2018 Aug 20;14(8):e1007127. doi: 10.1371/journal.ppat.1007127. eCollection 2018 Aug.

4.

Exogenous LRRK2G2019S induces parkinsonian-like pathology in a nonhuman primate.

Mestre-Francés N, Serratrice N, Gennetier A, Devau G, Cobo S, Trouche SG, Fontès P, Zussy C, De Deurwaerdere P, Salinas S, Mennechet FJ, Dusonchet J, Schneider BL, Saggio I, Kalatzis V, Luquin-Piudo MR, Verdier JM, Kremer EJ.

JCI Insight. 2018 Jul 25;3(14). pii: 98202. doi: 10.1172/jci.insight.98202. [Epub ahead of print]

5.

Identification of peptides with tolerogenic potential in a hydrolysed whey-based infant formula.

Gouw JW, Jo J, Meulenbroek LAPM, Heijjer TS, Kremer E, Sandalova E, Knulst AC, Jeurink PV, Garssen J, Rijnierse A, Knippels LMJ.

Clin Exp Allergy. 2018 Oct;48(10):1345-1353. doi: 10.1111/cea.13223. Epub 2018 Aug 14.

PMID:
29974988
6.

Subregion-Specific Proteomic Signature in the Hippocampus for Recognition Processes in Adult Mice.

von Ziegler LM, Selevsek N, Tweedie-Cullen RY, Kremer E, Mansuy IM.

Cell Rep. 2018 Mar 20;22(12):3362-3374. doi: 10.1016/j.celrep.2018.02.079.

7.

Thalamocortical and corticothalamic pathways differentially contribute to goal-directed behaviors in the rat.

Alcaraz F, Fresno V, Marchand AR, Kremer EJ, Coutureau E, Wolff M.

Elife. 2018 Feb 6;7. pii: e32517. doi: 10.7554/eLife.32517.

8.

Interplay between TETs and microRNAs in the adult brain for memory formation.

Kremer EA, Gaur N, Lee MA, Engmann O, Bohacek J, Mansuy IM.

Sci Rep. 2018 Jan 26;8(1):1678. doi: 10.1038/s41598-018-19806-z.

9.
10.

[Anti-adenovirus humoral immunity: impact on dendritic cell activation].

Mennechet FJD, Eichholz K, Tran TTP, Kremer EJ.

Med Sci (Paris). 2017 Jun-Jul;33(6-7):582-585. doi: 10.1051/medsci/20173306008. Epub 2017 Jul 19. French. No abstract available.

11.

Modular organization of the brainstem noradrenaline system coordinates opposing learning states.

Uematsu A, Tan BZ, Ycu EA, Cuevas JS, Koivumaa J, Junyent F, Kremer EJ, Witten IB, Deisseroth K, Johansen JP.

Nat Neurosci. 2017 Nov;20(11):1602-1611. doi: 10.1038/nn.4642. Epub 2017 Sep 18.

PMID:
28920933
12.

What is CAR doing in the middle of the adult neurogenic road?

Salinas S, Junyent F, Coré N, Cremer H, Kremer EJ.

Neurogenesis (Austin). 2017 Apr 27;4(1):e1304790. doi: 10.1080/23262133.2017.1304790. eCollection 2017.

13.

[The coxsackievirus and adenovirus receptor is involved in cognitive processes].

Zussy C, Loustalot F, Junyent F, Kremer EJ, Salinas S.

Med Sci (Paris). 2017 Jan;33(1):89-92. doi: 10.1051/medsci/20173301016. Epub 2017 Jan 25. French. No abstract available.

14.

Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells.

Eichholz K, Bru T, Tran TT, Fernandes P, Welles H, Mennechet FJ, Manel N, Alves P, Perreau M, Kremer EJ.

PLoS Pathog. 2016 Sep 16;12(9):e1005871. doi: 10.1371/journal.ppat.1005871. eCollection 2016 Sep.

15.

Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity.

Zussy C, Loustalot F, Junyent F, Gardoni F, Bories C, Valero J, Desarménien MG, Bernex F, Henaff D, Bayo-Puxan N, Chen JW, Lonjon N, de Koninck Y, Malva JO, Bergelson JM, di Luca M, Schiavo G, Salinas S, Kremer EJ.

J Neurosci. 2016 Sep 14;36(37):9558-71. doi: 10.1523/JNEUROSCI.0132-16.2016.

16.

The microRNA cluster miR-183/96/182 contributes to long-term memory in a protein phosphatase 1-dependent manner.

Woldemichael BT, Jawaid A, Kremer EA, Gaur N, Krol J, Marchais A, Mansuy IM.

Nat Commun. 2016 Aug 25;7:12594. doi: 10.1038/ncomms12594.

17.

Membrane Dynamics and Signaling of the Coxsackievirus and Adenovirus Receptor.

Loustalot F, Kremer EJ, Salinas S.

Int Rev Cell Mol Biol. 2016;322:331-62. doi: 10.1016/bs.ircmb.2015.10.006. Epub 2015 Dec 23.

PMID:
26940522
18.

Retrograde optogenetic characterization of the pontospinal module of the locus coeruleus with a canine adenoviral vector.

Li Y, Hickey L, Perrins R, Werlen E, Patel AA, Hirschberg S, Jones MW, Salinas S, Kremer EJ, Pickering AE.

Brain Res. 2016 Jun 15;1641(Pt B):274-90. doi: 10.1016/j.brainres.2016.02.023. Epub 2016 Feb 19.

19.

[Is there a risk of zoonotic disease due to adenoviruses?].

Loustalot F, Creyssels S, Salinas S, Benkõ M, Harrach B, Mennechet FJ, Kremer EJ.

Med Sci (Paris). 2015 Dec;31(12):1102-8. doi: 10.1051/medsci/20153112013. Epub 2015 Dec 16. Review. French.

20.

Ebola virus vaccine: benefit and risks of adenovirus-based vectors.

Mennechet FJ, Tran TT, Eichholz K, van de Perre P, Kremer EJ.

Expert Rev Vaccines. 2015;14(11):1471-8. doi: 10.1586/14760584.2015.1083429. Epub 2015 Aug 31. Review.

PMID:
26325242
21.

CAV-2--why a canine virus is a neurobiologist's best friend.

Junyent F, Kremer EJ.

Curr Opin Pharmacol. 2015 Oct;24:86-93. doi: 10.1016/j.coph.2015.08.004. Epub 2015 Aug 25. Review.

PMID:
26298516
22.

Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping.

Beier KT, Steinberg EE, DeLoach KE, Xie S, Miyamichi K, Schwarz L, Gao XJ, Kremer EJ, Malenka RC, Luo L.

Cell. 2015 Jul 30;162(3):622-34. doi: 10.1016/j.cell.2015.07.015.

23.

Transcriptional Response of Human Neurospheres to Helper-Dependent CAV-2 Vectors Involves the Modulation of DNA Damage Response, Microtubule and Centromere Gene Groups.

Piersanti S, Burla R, Licursi V, Brito C, La Torre M, Alves PM, Simao D, Mottini C, Salinas S, Negri R, Tagliafico E, Kremer EJ, Saggio I.

PLoS One. 2015 Jul 24;10(7):e0133607. doi: 10.1371/journal.pone.0133607. eCollection 2015.

24.

Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model.

Simão D, Pinto C, Fernandes P, Peddie CJ, Piersanti S, Collinson LM, Salinas S, Saggio I, Schiavo G, Kremer EJ, Brito C, Alves PM.

Gene Ther. 2016 Jan;23(1):86-94. doi: 10.1038/gt.2015.75. Epub 2015 Aug 20.

25.

The Intracellular Domain of the Coxsackievirus and Adenovirus Receptor Differentially Influences Adenovirus Entry.

Loustalot F, Kremer EJ, Salinas S.

J Virol. 2015 Sep;89(18):9417-26. doi: 10.1128/JVI.01488-15. Epub 2015 Jul 1.

26.

Viral-genetic tracing of the input-output organization of a central noradrenaline circuit.

Schwarz LA, Miyamichi K, Gao XJ, Beier KT, Weissbourd B, DeLoach KE, Ren J, Ibanes S, Malenka RC, Kremer EJ, Luo L.

Nature. 2015 Aug 6;524(7563):88-92. doi: 10.1038/nature14600. Epub 2015 Jul 1.

27.

Adenovirus tales: from the cell surface to the nuclear pore complex.

Kremer EJ, Nemerow GR.

PLoS Pathog. 2015 Jun 4;11(6):e1004821. doi: 10.1371/journal.ppat.1004821. eCollection 2015 Jun. Review. No abstract available.

28.

Canine helper-dependent vectors production: implications of Cre activity and co-infection on adenovirus propagation.

Fernandes P, Almeida AI, Kremer EJ, Alves PM, Coroadinha AS.

Sci Rep. 2015 Mar 16;5:9135. doi: 10.1038/srep09135.

29.

Ebola vaccines based on adenovirus vectors and risk of HIV.

Kremer EJ, Van de Perre P.

BMJ. 2015 Mar 10;350:h1307. doi: 10.1136/bmj.h1307. No abstract available.

PMID:
25757599
30.

Improvement of age-related memory impairment with infusion of young plasma: a role for the peripheral amyloid sink?

Jawaid A, Kremer EA, Piatek A, Schulz PE.

J Am Geriatr Soc. 2015 Feb;63(2):419-20. doi: 10.1111/jgs.13262. No abstract available.

PMID:
25688632
31.

Human coagulation factor X-adenovirus type 5 complexes poorly stimulate an innate immune response in human mononuclear phagocytes.

Eichholz K, Mennechet FJ, Kremer EJ.

J Virol. 2015 Mar;89(5):2884-91. doi: 10.1128/JVI.03576-14. Epub 2014 Dec 24.

32.

Impact of adenovirus life cycle progression on the generation of canine helper-dependent vectors.

Fernandes P, Simão D, Guerreiro MR, Kremer EJ, Coroadinha AS, Alves PM.

Gene Ther. 2015 Jan;22(1):40-9. doi: 10.1038/gt.2014.92. Epub 2014 Oct 23.

PMID:
25338917
33.

Modeling human neural functionality in vitro: three-dimensional culture for dopaminergic differentiation.

Simão D, Pinto C, Piersanti S, Weston A, Peddie CJ, Bastos AE, Licursi V, Schwarz SC, Collinson LM, Salinas S, Serra M, Teixeira AP, Saggio I, Lima PA, Kremer EJ, Schiavo G, Brito C, Alves PM.

Tissue Eng Part A. 2015 Feb;21(3-4):654-68. doi: 10.1089/ten.TEA.2014.0079. Epub 2014 Nov 11.

PMID:
25257211
34.

Synthesis, structural characterization and cytotoxic activity of ternary copper(II)-dipeptide-phenanthroline complexes. A step towards the development of new copper compounds for the treatment of cancer.

Iglesias S, Alvarez N, Torre MH, Kremer E, Ellena J, Ribeiro RR, Barroso RP, Costa-Filho AJ, Kramer MG, Facchin G.

J Inorg Biochem. 2014 Oct;139:117-23. doi: 10.1016/j.jinorgbio.2014.06.007. Epub 2014 Jun 17.

PMID:
25033418
35.

Do nonhuman primate or bat adenoviruses pose a risk for human health?

Benkő M, Harrach B, Kremer EJ.

Future Microbiol. 2014;9(3):269-72. doi: 10.2217/fmb.13.170. No abstract available.

PMID:
24762301
36.

Corrective GUSB transfer to the canine mucopolysaccharidosis VII cornea using a helper-dependent canine adenovirus vector.

Serratrice N, Cubizolle A, Ibanes S, Mestre-Francés N, Bayo-Puxan N, Creyssels S, Gennetier A, Bernex F, Verdier JM, Haskins ME, Couderc G, Malecaze F, Kalatzis V, Kremer EJ.

J Control Release. 2014 May 10;181:22-31. doi: 10.1016/j.jconrel.2014.02.022. Epub 2014 Mar 4.

37.

Corrective GUSB transfer to the canine mucopolysaccharidosis VII brain.

Cubizolle A, Serratrice N, Skander N, Colle MA, Ibanes S, Gennetier A, Bayo-Puxan N, Mazouni K, Mennechet F, Joussemet B, Cherel Y, Lajat Y, Vite C, Bernex F, Kalatzis V, Haskins ME, Kremer EJ.

Mol Ther. 2014 Apr;22(4):762-73. doi: 10.1038/mt.2013.283. Epub 2013 Dec 17.

38.

[Indices of matrix metalloproteinases (MMP-2, MMP-9, TIMP-1) with juvenile arthritis in children].

Kaĭlina AN, Ogorodova LM, Chasovskikh I, Kremer EE.

Vestn Ross Akad Med Nauk. 2013;(7):36-40. Russian.

PMID:
24340960
39.

Central nervous system delivery of helper-dependent canine adenovirus corrects neuropathology and behavior in mucopolysaccharidosis type VII mice.

Ariza L, Giménez-Llort L, Cubizolle A, Pagès G, García-Lareu B, Serratrice N, Cots D, Thwaite R, Chillón M, Kremer EJ, Bosch A.

Hum Gene Ther. 2014 Mar;25(3):199-211. doi: 10.1089/hum.2013.152. Epub 2014 Jan 23.

40.

Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting.

Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton PE, Parsons M, Schiavo G, Kremer EJ.

J Biol Chem. 2014 Jan 10;289(2):680-95. doi: 10.1074/jbc.M113.518365. Epub 2013 Nov 22.

41.

[Immunophenotypic characteristic of dendritic cells in bronchial asthma in conditions of extract opisthorchis felineus in vitro].

Kremer EÉ, Ogorodova LM, Kirillova NA, Khvorilova KV, Perevozchikova TV, Faĭt EA.

Vestn Ross Akad Med Nauk. 2013;(5):66-70. Russian.

PMID:
24000670
42.

Canine adenovirus type 2 vector generation via I-Sce1-mediated intracellular genome release.

Ibanes S, Kremer EJ.

PLoS One. 2013 Aug 1;8(8):e71032. doi: 10.1371/journal.pone.0071032. Print 2013.

43.

Differentiated neuroprogenitor cells incubated with human or canine adenovirus, or lentiviral vectors have distinct transcriptome profiles.

Piersanti S, Astrologo L, Licursi V, Costa R, Roncaglia E, Gennetier A, Ibanes S, Chillon M, Negri R, Tagliafico E, Kremer EJ, Saggio I.

PLoS One. 2013 Jul 26;8(7):e69808. doi: 10.1371/journal.pone.0069808. Print 2013.

44.

Combined antiapoptotic and antioxidant approach to acute neuroprotection for stroke in hypertensive rats.

Ord EN, Shirley R, McClure JD, McCabe C, Kremer EJ, Macrae IM, Work LM.

J Cereb Blood Flow Metab. 2013 Aug;33(8):1215-24. doi: 10.1038/jcbfm.2013.70. Epub 2013 May 1.

45.

Impact of E1 and Cre on adenovirus vector amplification: developing MDCK CAV-2-E1 and E1-Cre transcomplementing cell lines.

Fernandes P, Santiago VM, Rodrigues AF, Tomás H, Kremer EJ, Alves PM, Coroadinha AS.

PLoS One. 2013;8(4):e60342. doi: 10.1371/journal.pone.0060342. Epub 2013 Apr 2.

46.

Clinical and genetic findings in eight Israeli patients with transthyretin-associated familial amyloid polyneuropathy.

Leibou L, Frand J, Sadeh M, Lossos A, Kremer E, Livneh A, Yarnitsky D, Herman O, Dabby R.

Isr Med Assoc J. 2012 Nov;14(11):662-5.

47.

Adenoviruses - from pathogens to therapeutics: a report on the 10th International Adenovirus Meeting.

Greber UF, Arnberg N, Wadell G, Benkő M, Kremer EJ.

Cell Microbiol. 2013 Jan;15(1):16-23. doi: 10.1111/cmi.12031. Epub 2012 Oct 11. No abstract available.

PMID:
22985121
48.

Bioprocess development for canine adenovirus type 2 vectors.

Fernandes P, Peixoto C, Santiago VM, Kremer EJ, Coroadinha AS, Alves PM.

Gene Ther. 2013 Apr;20(4):353-60. doi: 10.1038/gt.2012.52. Epub 2012 Jul 5.

PMID:
22763405
49.

Corneal transduction by intra-stromal injection of AAV vectors in vivo in the mouse and ex vivo in human explants.

Hippert C, Ibanes S, Serratrice N, Court F, Malecaze F, Kremer EJ, Kalatzis V.

PLoS One. 2012;7(4):e35318. doi: 10.1371/journal.pone.0035318. Epub 2012 Apr 16.

50.

A Siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein.

Rademacher C, Bru T, McBride R, Robison E, Nycholat CM, Kremer EJ, Paulson JC.

Glycobiology. 2012 Aug;22(8):1086-91. doi: 10.1093/glycob/cws073. Epub 2012 Apr 21.

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