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Items: 1 to 50 of 166

1.

Reply to Ruprecht and Mayer: Unearthing genomic fossils in the pathogenesis of multiple sclerosis.

Kremer D, Perron H, Küry P.

Proc Natl Acad Sci U S A. 2019 Aug 27. pii: 201912315. doi: 10.1073/pnas.1912315116. [Epub ahead of print] No abstract available.

PMID:
31455745
2.

The Molecular Basis for Remyelination Failure in Multiple Sclerosis.

Gruchot J, Weyers V, Göttle P, Förster M, Hartung HP, Küry P, Kremer D.

Cells. 2019 Aug 3;8(8). pii: E825. doi: 10.3390/cells8080825. Review.

3.

Neural Cell Responses Upon Exposure to Human Endogenous Retroviruses.

Gruchot J, Kremer D, Küry P.

Front Genet. 2019 Jul 11;10:655. doi: 10.3389/fgene.2019.00655. eCollection 2019. Review.

4.

Drug Treatment of Clinically Isolated Syndrome.

Förster M, Graf J, Mares J, Aktas O, Hartung HP, Kremer D.

CNS Drugs. 2019 Jul;33(7):659-676. doi: 10.1007/s40263-019-00647-x. Review.

PMID:
31290079
5.

A large-scale analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics.

Lee HJ, Kremer DM, Sajjakulnukit P, Zhang L, Lyssiotis CA.

Metabolomics. 2019 Jul 9;15(7):103. doi: 10.1007/s11306-019-1564-8.

6.

pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis.

Kremer D, Gruchot J, Weyers V, Oldemeier L, Göttle P, Healy L, Ho Jang J, Kang T Xu Y, Volsko C, Dutta R, Trapp BD, Perron H, Hartung HP, Küry P.

Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15216-15225. doi: 10.1073/pnas.1901283116. Epub 2019 Jun 18.

PMID:
31213545
7.

Inhibition of Satellite RNA Associated Cucumber Mosaic Virus Infection by Essential Oil of Micromeria croatica (Pers.) Schott.

Vuko E, Rusak G, Dunkić V, Kremer D, Kosalec I, Rađa B, Bezić N.

Molecules. 2019 Apr 5;24(7). pii: E1342. doi: 10.3390/molecules24071342.

8.

Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma.

Xu J, Reznik E, Lee HJ, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra J, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka Z, Casuscelli J, Stirdivant S, Tang J, Schultz N, Jeng P, Dong Y, Su W, Cheng EH, Russo P, Coleman JA, Papaemmanuil E, Chen YB, Reuter VE, Sander C, Kennedy SR, Hsieh JJ, Lyssiotis CA, Tickoo SK, Hakimi AA.

Elife. 2019 Apr 1;8. pii: e38986. doi: 10.7554/eLife.38986.

9.

Remyelination in multiple sclerosis: from concept to clinical trials.

Kremer D, Göttle P, Flores-Rivera J, Hartung HP, Küry P.

Curr Opin Neurol. 2019 Jun;32(3):378-384. doi: 10.1097/WCO.0000000000000692.

PMID:
30865009
10.

Bio-adrenomedullin as a marker of congestion in patients with new-onset and worsening heart failure.

Ter Maaten JM, Kremer D, Demissei BG, Struck J, Bergmann A, Anker SD, Ng LL, Dickstein K, Metra M, Samani NJ, Romaine SPR, Cleland J, Girerd N, Lang CC, van Veldhuisen DJ, Voors AA.

Eur J Heart Fail. 2019 Jun;21(6):732-743. doi: 10.1002/ejhf.1437. Epub 2019 Mar 6.

PMID:
30843353
11.

Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.

Halbrook CJ, Pontious C, Kovalenko I, Lapienyte L, Dreyer S, Lee HJ, Thurston G, Zhang Y, Lazarus J, Sajjakulnukit P, Hong HS, Kremer DM, Nelson BS, Kemp S, Zhang L, Chang D, Biankin A, Shi J, Frankel TL, Crawford HC, Morton JP, Pasca di Magliano M, Lyssiotis CA.

Cell Metab. 2019 Jun 4;29(6):1390-1399.e6. doi: 10.1016/j.cmet.2019.02.001. Epub 2019 Feb 28.

PMID:
30827862
12.

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.

Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaaq1427. doi: 10.1126/scitranslmed.aaq1427.

13.

Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC-MS/MS.

Yuan M, Kremer DM, Huang H, Breitkopf SB, Ben-Sahra I, Manning BD, Lyssiotis CA, Asara JM.

Nat Protoc. 2019 Feb;14(2):313-330. doi: 10.1038/s41596-018-0102-x.

PMID:
30683937
14.

Long-term follow-up of multiple sclerosis studies and outcomes from early treatment of clinically isolated syndrome in the BENEFIT 11 study.

Hartung HP, Graf J, Kremer D.

J Neurol. 2019 Jan 4. doi: 10.1007/s00415-018-09169-w. [Epub ahead of print] Review.

PMID:
30610426
15.

Managing Risks with Immune Therapies in Multiple Sclerosis.

Förster M, Küry P, Aktas O, Warnke C, Havla J, Hohlfeld R, Mares J, Hartung HP, Kremer D.

Drug Saf. 2019 May;42(5):633-647. doi: 10.1007/s40264-018-0782-8. Review.

PMID:
30607830
16.

Adrenomedullin in heart failure: pathophysiology and therapeutic application.

Voors AA, Kremer D, Geven C, Ter Maaten JM, Struck J, Bergmann A, Pickkers P, Metra M, Mebazaa A, Düngen HD, Butler J.

Eur J Heart Fail. 2019 Feb;21(2):163-171. doi: 10.1002/ejhf.1366. Epub 2018 Dec 28. Review.

17.

Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination.

Göttle P, Förster M, Gruchot J, Kremer D, Hartung HP, Perron H, Küry P.

Glia. 2019 Jan;67(1):160-170. doi: 10.1002/glia.23535. Epub 2018 Nov 14.

PMID:
30430656
18.

Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.

Holt MC, Assar Z, Beheshti Zavareh R, Lin L, Anglin J, Mashadova O, Haldar D, Mullarky E, Kremer DM, Cantley LC, Kimmelman AC, Stein AJ, Lairson LL, Lyssiotis CA.

Biochemistry. 2018 Nov 27;57(47):6604-6614. doi: 10.1021/acs.biochem.8b00914. Epub 2018 Nov 12.

PMID:
30365304
19.

New tricks for an old drug.

Nelson BS, Kremer DM, Lyssiotis CA.

Nat Chem Biol. 2018 Nov;14(11):990-991. doi: 10.1038/s41589-018-0137-x. No abstract available.

PMID:
30297874
20.

Current advancements in promoting remyelination in multiple sclerosis.

Kremer D, Akkermann R, Küry P, Dutta R.

Mult Scler. 2019 Jan;25(1):7-14. doi: 10.1177/1352458518800827. Epub 2018 Oct 1.

PMID:
30270725
21.

Drug repurposing for neuroregeneration in multiple sclerosis.

Küry P, Kremer D, Göttle P.

Neural Regen Res. 2018 Aug;13(8):1366-1367. doi: 10.4103/1673-5374.235242. No abstract available.

22.

Bio-adrenomedullin as a potential quick, reliable, and objective marker of congestion in heart failure.

Kremer D, Ter Maaten JM, Voors AA.

Eur J Heart Fail. 2018 Sep;20(9):1363-1365. doi: 10.1002/ejhf.1245. Epub 2018 Jun 22. No abstract available.

23.

Menin regulates the serine biosynthetic pathway in Ewing sarcoma.

Svoboda LK, Teh SSK, Sud S, Kerk S, Zebolsky A, Treichel S, Thomas D, Halbrook CJ, Lee HJ, Kremer D, Zhang L, Klossowski S, Bankhead AR, Magnuson B, Ljungman M, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER.

J Pathol. 2018 Jul;245(3):324-336. doi: 10.1002/path.5085. Epub 2018 May 28.

24.

ECTRIMS/ACTRIMS 2017: Closing in on neurorepair in progressive multiple sclerosis.

Kremer D, Küry P, Hartung HP.

Mult Scler. 2018 May;24(6):696-700. doi: 10.1177/1352458518768770. Epub 2018 Apr 9. Review.

PMID:
29629605
25.

Teriflunomide promotes oligodendroglial differentiation and myelination.

Göttle P, Manousi A, Kremer D, Reiche L, Hartung HP, Küry P.

J Neuroinflammation. 2018 Mar 13;15(1):76. doi: 10.1186/s12974-018-1110-z.

26.

Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.

Schofield HK, Zeller J, Espinoza C, Halbrook CJ, Del Vecchio A, Magnuson B, Fabo T, Daylan AEC, Kovalenko I, Lee HJ, Yan W, Feng Y, Karim SA, Kremer DM, Kumar-Sinha C, Lyssiotis CA, Ljungman M, Morton JP, Galbán S, Fearon ER, Pasca di Magliano M.

JCI Insight. 2018 Jan 25;3(2). pii: 97422. doi: 10.1172/jci.insight.97422. eCollection 2018 Jan 25.

27.

Response to 'Classification of cerebral palsy and potential role of video recording'.

Eggink H, Kremer D, Tijssen MAJ.

Eur J Paediatr Neurol. 2018 Jan;22(1):211-212. doi: 10.1016/j.ejpn.2017.10.002. Epub 2017 Oct 9. No abstract available.

PMID:
29046250
28.

Prehistoric enemies within: The contribution of human endogenous retroviruses to neurological diseases. Meeting report: "Second International Workshop on Human Endogenous Retroviruses and Disease", Washington DC, March 13th and 14th 2017.

Kremer D, Glanzman R, Traboulsee A, Nath A, Groc L, Horwitz M, Göttle P, Perron H, Gold J, Hartung HP, Küry P.

Mult Scler Relat Disord. 2017 Jul;15:18-23. doi: 10.1016/j.msard.2017.05.001. Epub 2017 May 1.

PMID:
28641767
29.

Spasticity, dyskinesia and ataxia in cerebral palsy: Are we sure we can differentiate them?

Eggink H, Kremer D, Brouwer OF, Contarino MF, van Egmond ME, Elema A, Folmer K, van Hoorn JF, van de Pol LA, Roelfsema V, Tijssen MAJ.

Eur J Paediatr Neurol. 2017 Sep;21(5):703-706. doi: 10.1016/j.ejpn.2017.04.1333. Epub 2017 May 9.

PMID:
28549726
30.

Assessment of Drying Characteristics and Texture in 
Relation with Micromorphological Traits of Carob 
(Ceratonia silliqua L.) Pods and Seeds.

Benković M, Srečec S, Bauman I, Ježek D, Karlović S, Kremer D, Karlović K, Erhatić R.

Food Technol Biotechnol. 2016 Dec;54(4):432-440. doi: 10.17113/ftb.54.04.16.4475.

31.

Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC.

Nature. 2016 Dec 1;540(7631):150. doi: 10.1038/nature19851. Epub 2016 Oct 5. No abstract available.

PMID:
27706144
32.

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC.

Nature. 2016 Aug 25;536(7617):479-83. doi: 10.1038/nature19084. Epub 2016 Aug 10. Erratum in: Nature. 2016 Dec 1;540(7631):150.

33.

Pushing Forward: Remyelination as the New Frontier in CNS Diseases.

Kremer D, Göttle P, Hartung HP, Küry P.

Trends Neurosci. 2016 Apr;39(4):246-263. doi: 10.1016/j.tins.2016.02.004. Epub 2016 Mar 7. Review.

PMID:
26964504
34.

CXCR7 Is Involved in Human Oligodendroglial Precursor Cell Maturation.

Kremer D, Cui QL, Göttle P, Kuhlmann T, Hartung HP, Antel J, Küry P.

PLoS One. 2016 Jan 7;11(1):e0146503. doi: 10.1371/journal.pone.0146503. eCollection 2016.

35.

Quantitative analysis of arbutin and hydroquinone in strawberry tree (Arbutus unedo L., Ericaceae) leaves by gas chromatography-mass spectrometry.

Jurica K, Karačonji IB, Šegan S, Opsenica DM, Kremer D.

Arh Hig Rada Toksikol. 2015 Sep 1;66(3):197-202. doi: 10.1515/aiht-2015-66-2696.

PMID:
26444340
36.

Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER.

Suchiman HE, Slieker RC, Kremer D, Slagboom PE, Heijmans BT, Tobi EW.

Front Genet. 2015 Sep 17;6:287. doi: 10.3389/fgene.2015.00287. eCollection 2015.

37.

Targeting semaphorins in MS as a treatment strategy to promote remyelination: A tale of mice, rats and men.

Kremer D, Hartung HP, Küry P.

Mult Scler. 2015 Nov;21(13):1616-7. doi: 10.1177/1352458515608693. Epub 2015 Oct 2. No abstract available.

PMID:
26432852
38.

Toxicity and antioxidant capacity of Frangula alnus Mill. bark and its active component emodin.

Brkanac SR, Gerić M, Gajski G, Vujčić V, Garaj-Vrhovac V, Kremer D, Domijan AM.

Regul Toxicol Pharmacol. 2015 Dec;73(3):923-9. doi: 10.1016/j.yrtph.2015.09.025. Epub 2015 Sep 21.

PMID:
26399165
39.

[New therapeutic strategies for remyelination in multiple sclerosis].

Kremer D, Hartung HP, Stangel M, Küry P.

Nervenarzt. 2015 Aug;86(8):934-46. doi: 10.1007/s00115-014-4249-6. German.

PMID:
26122637
40.

Antioxidant and Antimicrobial Properties of Veronica spicata L. (Plantaginaceae).

Dunkić V, Kosalec I, Kosir IJ, Potocnik T, Cerenak A, Koncic MZ, Vitali D, Muller ID, Kopricanec M, Bezic N, Srecec S, Kremer D.

Curr Drug Targets. 2015;16(14):1660-70.

PMID:
26028041
41.

Genetic and phytochemical variability of six Teucrium arduini L. populations and their antioxidant/prooxidant behaviour examined by biochemical, macromolecule- and cell-based approaches.

Šamec D, Durgo K, Grúz J, Kremer D, Kosalec I, Piljac-Žegarac J, Salopek-Sondi B.

Food Chem. 2015 Nov 1;186:298-305. doi: 10.1016/j.foodchem.2014.07.135. Epub 2014 Aug 8.

PMID:
25976825
42.

Morphological, genetic and phytochemical variation of the endemic Teucrium arduini L. (Lamiaceae).

Kremer D, Bolarić S, Ballian D, Bogunić F, Stešević D, Karlović K, Kosalec I, Vokurka A, Vuković Rodríguez J, Randić M, Bezić N, Dunkić V.

Phytochemistry. 2015 Aug;116:111-119. doi: 10.1016/j.phytochem.2015.04.003. Epub 2015 Apr 27.

PMID:
25931417
43.

More light on the 2(ν5) Raman overtone of SF6: can a weak anisotropic spectrum be due to a strong transition anisotropy?

Kremer D, Rachet F, Chrysos M.

J Chem Phys. 2014 Jan 21;140(3):034308. doi: 10.1063/1.4861047.

PMID:
25669380
44.

Antimicrobial and Antioxidant Properties of Satureja Montana L. and S. Subspicata Vis. (Lamiaceae).

Kremer D, Košir IJ, Končić MZ, Čerenak A, Potočnik T, Srečec S, Randić M, Kosalec I.

Curr Drug Targets. 2015;16(14):1623-33.

PMID:
25642718
45.

Promoting remyelination in multiple sclerosis: current drugs and future prospects.

Kremer D, Küry P, Dutta R.

Mult Scler. 2015 Apr;21(5):541-9. doi: 10.1177/1352458514566419. Epub 2015 Jan 26. Review.

PMID:
25623245
46.

Oligodendroglial maturation is dependent on intracellular protein shuttling.

Göttle P, Sabo JK, Heinen A, Venables G, Torres K, Tzekova N, Parras CM, Kremer D, Hartung HP, Cate HS, Küry P.

J Neurosci. 2015 Jan 21;35(3):906-19. doi: 10.1523/JNEUROSCI.1423-14.2015.

47.

Molecular and cellular approach in the study of antioxidant/pro-oxidant properties of Micromeria croatica (Pers.) Schott.

Šamec D, Gruz J, Durgo K, Kremer D, Kosalec I, Žulj LV, Martinez S, Salopek-Sondi B, Piljac-Žegarac J.

Nat Prod Res. 2015;29(18):1770-4. doi: 10.1080/14786419.2014.999334. Epub 2015 Jan 19.

PMID:
25597227
48.

The neutralizing antibody GNbAC1 abrogates HERV-W envelope protein-mediated oligodendroglial maturation blockade.

Kremer D, Förster M, Schichel T, Göttle P, Hartung HP, Perron H, Küry P.

Mult Scler. 2015 Aug;21(9):1200-3. doi: 10.1177/1352458514560926. Epub 2014 Dec 5.

PMID:
25480862
49.

The 2ν(3) Raman overtone of sulfur hexafluoride: absolute spectra, pressure effects, and polarizability properties.

Chrysos M, Rachet F, Kremer D.

J Chem Phys. 2014 Mar 28;140(12):124308. doi: 10.1063/1.4869097.

PMID:
24697442
50.

Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancers.

Spaans VM, Trietsch MD, Crobach S, Stelloo E, Kremer D, Osse EM, Haar NT, van Eijk R, Muller S, van Wezel T, Trimbos JB, Bosse T, Smit VT, Fleuren GJ.

PLoS One. 2014 Mar 26;9(3):e93451. doi: 10.1371/journal.pone.0093451. eCollection 2014.

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