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The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro.

Verhees F, Legemaate D, Demers I, Jacobs R, Haakma WE, Rousch M, Kremer B, Speel EJ.

Cancers (Basel). 2019 Jun 30;11(7). pii: E919. doi: 10.3390/cancers11070919.


Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.

Bell CC, Fennell KA, Chan YC, Rambow F, Yeung MM, Vassiliadis D, Lara L, Yeh P, Martelotto LG, Rogiers A, Kremer BE, Barbash O, Mohammad HP, Johanson TM, Burr ML, Dhar A, Karpinich N, Tian L, Tyler DS, MacPherson L, Shi J, Pinnawala N, Yew Fong C, Papenfuss AT, Grimmond SM, Dawson SJ, Allan RS, Kruger RG, Vakoc CR, Goode DL, Naik SH, Gilan O, Lam EYN, Marine JC, Prinjha RK, Dawson MA.

Nat Commun. 2019 Jun 20;10(1):2723. doi: 10.1038/s41467-019-10652-9.


Detecting recurrent head and neck cancer using electronic nose technology: A feasibility study.

van de Goor RMGE, Hardy JCA, van Hooren MRA, Kremer B, Kross KW.

Head Neck. 2019 Sep;41(9):2983-2990. doi: 10.1002/hed.25787. Epub 2019 Apr 23.


Association Between Pharyngeal Pooling and Aspiration Using Fiberoptic Endoscopic Evaluation of Swallowing in Head and Neck Cancer Patients with Dysphagia.

Simon SR, Florie M, Pilz W, Winkens B, Winter N, Kremer B, Baijens LWJ.

Dysphagia. 2019 Mar 13. doi: 10.1007/s00455-019-09992-x. [Epub ahead of print]


"Ears of the Lynx" MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia.

Pascual B, de Bot ST, Daniels MR, França MC Jr, Toro C, Riverol M, Hedera P, Bassi MT, Bresolin N, van de Warrenburg BP, Kremer B, Nicolai J, Charles P, Xu J, Singh S, Patronas NJ, Fung SH, Gregory MD, Masdeu JC.

AJNR Am J Neuroradiol. 2019 Jan;40(1):199-203. doi: 10.3174/ajnr.A5935. Epub 2019 Jan 3.


Effects of dietary chromium propionate on growth performance, metabolism, and immune biomarkers in heat-stressed finishing pigs1.

Mayorga EJ, Kvidera SK, Seibert JT, Horst EA, Abuajamieh M, Al-Qaisi M, Lei S, Ross JW, Johnson CD, Kremer B, Ochoa L, Rhoads RP, Baumgard LH.

J Anim Sci. 2019 Mar 1;97(3):1185-1197. doi: 10.1093/jas/sky484.


Diagnosis and treatment of oropharyngeal dysphagia after total laryngectomy with or without pharyngoesophageal reconstruction: Systematic review.

Terlingen LT, Pilz W, Kuijer M, Kremer B, Baijens LW.

Head Neck. 2018 Dec;40(12):2733-2748. doi: 10.1002/hed.25508. Epub 2018 Nov 26. Review.


Upregulation of AKR1C1 and AKR1C3 expression in OPSCC with integrated HPV16 and HPV-negative tumors is an indicator of poor prognosis.

Huebbers CU, Verhees F, Poluschkin L, Olthof NC, Kolligs J, Siefer OG, Henfling M, Ramaekers FCS, Preuss SF, Beutner D, Seehawer J, Drebber U, Korkmaz Y, Lam WL, Vucic EA, Kremer B, Klussmann JP, Speel EM.

Int J Cancer. 2019 May 15;144(10):2465-2477. doi: 10.1002/ijc.31954. Epub 2019 Jan 30.


Eosinophilia and reduced STAT3 signaling affect neutrophil cell death in autosomal-dominant Hyper-IgE syndrome.

Farmand S, Kremer B, Häffner M, Pütsep K, Bergman P, Sundin M, Ritterbusch H, Seidl M, Follo M, Henneke P, Henriques-Normark B.

Eur J Immunol. 2018 Dec;48(12):1975-1988. doi: 10.1002/eji.201847650. Epub 2018 Oct 29.


DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A.

Cell. 2018 Aug 23;174(5):1325-1326. doi: 10.1016/j.cell.2018.08.015. No abstract available.


Medically Unexplained Oropharyngeal Dysphagia at the University Hospital ENT Outpatient Clinic for Dysphagia: A Cross-Sectional Cohort Study.

Verdonschot RJCG, Baijens LWJ, Vanbelle S, Florie M, Dijkman R, Leeters IPM, Kremer B, Leue C.

Dysphagia. 2019 Feb;34(1):43-51. doi: 10.1007/s00455-018-9912-9. Epub 2018 Jun 5.


The prevalence and severity of disease-related disabilities and their impact on quality of life in neuromuscular diseases.

Bos I, Wynia K, Almansa J, Drost G, Kremer B, Kuks J.

Disabil Rehabil. 2019 Jul;41(14):1676-1681. doi: 10.1080/09638288.2018.1446188. Epub 2018 Mar 8.


Training and Validating a Portable Electronic Nose for Lung Cancer Screening.

van de Goor R, van Hooren M, Dingemans AM, Kremer B, Kross K.

J Thorac Oncol. 2018 May;13(5):676-681. doi: 10.1016/j.jtho.2018.01.024. Epub 2018 Feb 6.


Decisional needs assessment of patients with complex care needs in primary care: a participatory systematic mixed studies review protocol.

Bujold M, Pluye P, Légaré F, Haggerty J, Gore GC, Sherif RE, Poitras ME, Beaulieu MC, Beaulieu MD, Bush PL, Couturier Y, Débarges B, Gagnon J, Giguère A, Grad R, Granikov V, Goulet S, Hudon C, Kremer B, Kröger E, Kudrina I, Lebouché B, Loignon C, Lussier MT, Martello C, Nguyen Q, Pratt R, Rihoux B, Rosenberg E, Samson I, Senn N, Li Tang D, Tsujimoto M, Vedel I, Ventelou B, Wensing M; Participatory Review Team.

BMJ Open. 2017 Nov 12;7(11):e016400. doi: 10.1136/bmjopen-2017-016400.


Observer Agreement for Measurements in Videolaryngostroboscopy.

Brunings JW, Vanbelle S, Akkermans A, Heemskerk NMM, Kremer B, Stokroos RJ, Baijens LWJ.

J Voice. 2018 Nov;32(6):756-762. doi: 10.1016/j.jvoice.2017.09.005. Epub 2017 Nov 6.


Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia.

Nibbeling EAR, Duarri A, Verschuuren-Bemelmans CC, Fokkens MR, Karjalainen JM, Smeets CJLM, de Boer-Bergsma JJ, van der Vries G, Dooijes D, Bampi GB, van Diemen C, Brunt E, Ippel E, Kremer B, Vlak M, Adir N, Wijmenga C, van de Warrenburg BPC, Franke L, Sinke RJ, Verbeek DS.

Brain. 2017 Nov 1;140(11):2860-2878. doi: 10.1093/brain/awx251.


Xenon Reduces Neuronal Hippocampal Damage and Alters the Pattern of Microglial Activation after Experimental Subarachnoid Hemorrhage: A Randomized Controlled Animal Trial.

Veldeman M, Coburn M, Rossaint R, Clusmann H, Nolte K, Kremer B, Höllig A.

Front Neurol. 2017 Sep 27;8:511. doi: 10.3389/fneur.2017.00511. eCollection 2017.


Argon attenuates the emergence of secondary injury after traumatic brain injury within a 2-hour incubation period compared to desflurane: an in vitro study.

Grüßer L, Blaumeiser-Debarry R, Krings M, Kremer B, Höllig A, Rossaint R, Coburn M.

Med Gas Res. 2017 Jun 30;7(2):93-100. doi: 10.4103/2045-9912.208512. eCollection 2017 Apr-Jun. Erratum in: Med Gas Res. 2017 Oct 17;7(3):155.


Corrigendum to "Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging" [Radiother Oncol 113 (2014) 324-30].

Velazquez ER, Hoebers F, Aerts HJWL, Rietbergen MM, Brakenhoff RH, Leemans RC, Speel EJ, Straetmans J, Kremer B, Lambin P.

Radiother Oncol. 2017 Aug;124(2):337-338. doi: 10.1016/j.radonc.2017.06.017. Epub 2017 Jul 11. No abstract available.


Spontaneous remission of acute myeloid leukemia after discontinuation of lenalidomide.

Kremer B, Tsai DE, Debonera F, Cohen PL, Schuster SJ.

Leuk Lymphoma. 2018 Mar;59(3):743-745. doi: 10.1080/10428194.2017.1347652. Epub 2017 Jul 11. No abstract available.


Methadone versus Fentanyl in Patients with Radiation-Induced Nociceptive Pain with Head and Neck Cancer: A Randomized Controlled Noninferiority Trial.

Haumann J, van Kuijk SMJ, Geurts JW, Hoebers FJP, Kremer B, Joosten EA, van den Beuken-van Everdingen MHJ.

Pain Pract. 2018 Mar;18(3):331-340. doi: 10.1111/papr.12609. Epub 2017 Aug 28.


[Delayed diagnosis of Huntington's disease in a psychiatric setting].

Tak LM, Sizoo B, de Stegge BMA, Adema S, van Duijn E, Kremer B.

Tijdschr Psychiatr. 2017;59(6):372-375. Dutch.


Affective symptoms in patients with oropharyngeal dysphagia: A systematic review.

Verdonschot RJCG, Baijens LWJ, Vanbelle S, van de Kolk I, Kremer B, Leue C.

J Psychosom Res. 2017 Jun;97:102-110. doi: 10.1016/j.jpsychores.2017.04.006. Epub 2017 Apr 20. Review.


Intake of meat and fish and risk of head-neck cancer subtypes in the Netherlands Cohort Study.

Perloy A, Maasland DHE, van den Brandt PA, Kremer B, Schouten LJ.

Cancer Causes Control. 2017 Jun;28(6):647-656. doi: 10.1007/s10552-017-0892-0. Epub 2017 Apr 5.


Diffusion tensor imaging and tractography of the white matter in normal aging: The rate-of-change differs between segments within tracts.

Mårtensson J, Lätt J, Åhs F, Fredrikson M, Söderlund H, Schiöth HB, Kok J, Kremer B, van Westen D, Larsson EM, Nilsson M.

Magn Reson Imaging. 2018 Jan;45:113-119. doi: 10.1016/j.mri.2017.03.007. Epub 2017 Mar 27.


Chromosome instability in tumor resection margins of primary OSCC is a predictor of local recurrence.

Pierssens DDCG, Borgemeester MC, van der Heijden SJH, Peutz-Kootstra CJ, Ruland AM, Haesevoets AM, Kessler PAWH, Kremer B, Speel EM.

Oral Oncol. 2017 Mar;66:14-21. doi: 10.1016/j.oraloncology.2016.12.029. Epub 2017 Jan 6.


The impact of micronutrient status on health: correlation network analysis to understand the role of micronutrients in metabolic-inflammatory processes regulating homeostasis and phenotypic flexibility.

van den Broek TJ, Kremer BHA, Marcondes Rezende M, Hoevenaars FPM, Weber P, Hoeller U, van Ommen B, Wopereis S.

Genes Nutr. 2017 Feb 8;12:5. doi: 10.1186/s12263-017-0553-7. eCollection 2017.


Experiences and preferences of patients visiting a head and neck oncology outpatient clinic: a qualitative study.

Bisschop JAS, Kloosterman FR, van Leijen-Zeelenberg JE, Huismans GW, Kremer B, Kross KW.

Eur Arch Otorhinolaryngol. 2017 May;274(5):2245-2252. doi: 10.1007/s00405-017-4453-7. Epub 2017 Jan 28.


DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.

Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A.

Cell. 2016 Nov 17;167(5):1264-1280.e18. doi: 10.1016/j.cell.2016.09.054. Epub 2016 Oct 27. Erratum in: Cell. 2018 Aug 23;174(5):1325-1326.


Item Response Theory Applied to Factors Affecting the Patient Journey Towards Hearing Rehabilitation.

Chenault M, Berger M, Kremer B, Anteunis L.

Audiol Res. 2016 Nov 30;6(2):159. doi: 10.4081/audiores.2016.159. eCollection 2016 Aug 23.


Letter response: Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.

Haumann J, Geurts JW, van Kuijk SM, Kremer B, Joosten EA, van den Beuken-van Everdingen MH.

Eur J Cancer. 2016 Nov;68:201-202. doi: 10.1016/j.ejca.2016.09.014. Epub 2016 Oct 19. No abstract available.


Feasibility of electronic nose technology for discriminating between head and neck, bladder, and colon carcinomas.

van de Goor RM, Leunis N, van Hooren MR, Francisca E, Masclee A, Kremer B, Kross KW.

Eur Arch Otorhinolaryngol. 2017 Feb;274(2):1053-1060. doi: 10.1007/s00405-016-4320-y. Epub 2016 Oct 11.


Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.

Haumann J, Geurts JW, van Kuijk SM, Kremer B, Joosten EA, van den Beuken-van Everdingen MH.

Eur J Cancer. 2016 Sep;65:121-9. doi: 10.1016/j.ejca.2016.06.025. Epub 2016 Aug 3.


Quantifiable risk-benefit assessment of micronutrients: From theory to practice.

Krul L, Kremer BHA, Luijckx NBL, Leeman WR.

Crit Rev Food Sci Nutr. 2017 Nov 22;57(17):3729-3746. doi: 10.1080/10408398.2016.1162765. Review.


The Raman-Derived Carbonization Continuum: A Tool to Select the Best Preserved Molecular Structures in Archean Kerogens.

Delarue F, Rouzaud JN, Derenne S, Bourbin M, Westall F, Kremer B, Sugitani K, Deldicque D, Robert F.

Astrobiology. 2016 Jun;16(6):407-17. doi: 10.1089/ast.2015.1392. Epub 2016 May 17.


Differentiating head and neck carcinoma from lung carcinoma with an electronic nose: a proof of concept study.

van Hooren MR, Leunis N, Brandsma DS, Dingemans AC, Kremer B, Kross KW.

Eur Arch Otorhinolaryngol. 2016 Nov;273(11):3897-3903. Epub 2016 Apr 16.


Toenail selenium status and risk of subtypes of head-neck cancer: The Netherlands Cohort Study.

Maasland DH, Schouten LJ, Kremer B, van den Brandt PA.

Eur J Cancer. 2016 Jun;60:83-92. doi: 10.1016/j.ejca.2016.03.003. Epub 2016 Apr 13.


Spectroscopic Studies on Organic Matter from Triassic Reptile Bones, Upper Silesia, Poland.

Surmik D, Boczarowski A, Balin K, Dulski M, Szade J, Kremer B, Pawlicki R.

PLoS One. 2016 Mar 15;11(3):e0151143. doi: 10.1371/journal.pone.0151143. eCollection 2016.


Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a multicentre cohort study.

O'Sullivan B, Huang SH, Su J, Garden AS, Sturgis EM, Dahlstrom K, Lee N, Riaz N, Pei X, Koyfman SA, Adelstein D, Burkey BB, Friborg J, Kristensen CA, Gothelf AB, Hoebers F, Kremer B, Speel EJ, Bowles DW, Raben D, Karam SD, Yu E, Xu W.

Lancet Oncol. 2016 Apr;17(4):440-451. doi: 10.1016/S1470-2045(15)00560-4. Epub 2016 Feb 27.


Fungal Ferromanganese Mineralisation in Cretaceous Dinosaur Bones from the Gobi Desert, Mongolia.

Owocki K, Kremer B, Wrzosek B, Królikowska A, Kaźmierczak J.

PLoS One. 2016 Feb 10;11(2):e0146293. doi: 10.1371/journal.pone.0146293. eCollection 2016.


Observers' Agreement on Measurements in Fiberoptic Endoscopic Evaluation of Swallowing.

Pilz W, Vanbelle S, Kremer B, van Hooren MR, van Becelaere T, Roodenburg N, Baijens LW.

Dysphagia. 2016 Apr;31(2):180-7. doi: 10.1007/s00455-015-9673-7. Epub 2016 Jan 23.


The impact of redesigning care processes on quality of care: a systematic review.

van Leijen-Zeelenberg JE, Elissen AMJ, Grube K, van Raak AJA, Vrijhoef HJM, Kremer B, Ruwaard D.

BMC Health Serv Res. 2016 Jan 19;16:19. doi: 10.1186/s12913-016-1266-0. Review.


Intrauterine Lipopolysaccharide-Induced Chorioamnionitis in a Sheep: Does It Affect the Auditory System?

Smit AL, Lambermont VA, Stokroos RJ, Anteunis LJ, Chenault MN, Schaefer SM, Schoenmakers LW, Kremer B, Kramer BW.

Reprod Sci. 2016 Feb;23(2):257-63. doi: 10.1177/1933719115602759. Epub 2015 Dec 23.


Relationship between swallow-specific quality of life and fiber-optic endoscopic evaluation of swallowing findings in patients with head and neck cancer.

Florie M, Baijens L, Kremer B, Kross K, Lacko M, Verhees F, Winkens B.

Head Neck. 2016 Apr;38 Suppl 1:E1848-56. doi: 10.1002/hed.24333. Epub 2015 Dec 23.


Body mass index and risk of subtypes of head-neck cancer: the Netherlands Cohort Study.

Maasland DH, van den Brandt PA, Kremer B, Schouten LJ.

Sci Rep. 2015 Dec 4;5:17744. doi: 10.1038/srep17744.


Using Lean Thinking at an otorhinolaryngology outpatient clinic to improve quality of care.

van Leijen-Zeelenberg JE, Brunings JW, Houkes I, van Raak AJ, Ruwaard D, Vrijhoef HJ, Kremer B.

Laryngoscope. 2016 Apr;126(4):839-46. doi: 10.1002/lary.25741. Epub 2015 Nov 3.


The relationship between fiberoptic endoscopic evaluation of swallowing outcome and symptoms of anxiety and depression in dysphagic patients.

Verdonschot RJ, Baijens L, Vanbelle S, Florie M, Kremer B, Leue C.

Laryngoscope. 2016 May;126(5):E199-207. doi: 10.1002/lary.25698. Epub 2015 Oct 9.


Blood-brain barrier disruption during spontaneous canine visceral leishmaniasis.

Melo GD, Grano FG, Silva JE, Kremer BE, Lima VM, Machado GF.

Parasite Immunol. 2015 Dec;37(12):635-45. doi: 10.1111/pim.12285.


Low-grade inflammation, diet composition and health: current research evidence and its translation.

Minihane AM, Vinoy S, Russell WR, Baka A, Roche HM, Tuohy KM, Teeling JL, Blaak EE, Fenech M, Vauzour D, McArdle HJ, Kremer BH, Sterkman L, Vafeiadou K, Benedetti MM, Williams CM, Calder PC.

Br J Nutr. 2015 Oct 14;114(7):999-1012. doi: 10.1017/S0007114515002093. Epub 2015 Jul 31. Review.


Identifying Patterns of FEES-Derived Swallowing Trajectories Using Group-Based Trajectory Model.

Baijens LW, Pilz W, Kremer B, Passos VL.

Dysphagia. 2015 Oct;30(5):529-39. doi: 10.1007/s00455-015-9632-3. Epub 2015 Jul 25.

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