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Items: 39

1.

Copper-mediated thiol potentiation and mutagenesis-guided modeling suggest a highly conserved copper-binding motif in human OR2M3.

Haag F, Ahmed L, Reiss K, Block E, Batista VS, Krautwurst D.

Cell Mol Life Sci. 2019 Aug 21. doi: 10.1007/s00018-019-03279-y. [Epub ahead of print]

PMID:
31435697
2.

Beyond the Flavour: The Potential Druggability of Chemosensory G Protein-Coupled Receptors.

Di Pizio A, Behrens M, Krautwurst D.

Int J Mol Sci. 2019 Mar 20;20(6). pii: E1402. doi: 10.3390/ijms20061402. Review.

3.

Food sources and biomolecular targets of tyramine.

Andersen G, Marcinek P, Sulzinger N, Schieberle P, Krautwurst D.

Nutr Rev. 2019 Feb 1;77(2):107-115. doi: 10.1093/nutrit/nuy036.

PMID:
30165672
4.

Current Status and Future Perspectives in Flavor Research: Highlights of the 11th Wartburg Symposium on Flavor Chemistry & Biology.

Hofmann T, Krautwurst D, Schieberle P.

J Agric Food Chem. 2018 Mar 14;66(10):2197-2203. doi: 10.1021/acs.jafc.7b06144.

PMID:
29298062
5.

A bi-functional IL-6-HaloTag® as a tool to measure the cell-surface expression of recombinant odorant receptors and to facilitate their activity quantification.

Noe F, Geithe C, Fiedler J, Krautwurst D.

J Biol Methods. 2017 Dec 15;4(4):e82. doi: 10.14440/jbm.2017.207. eCollection 2017.

6.

IL-6-HaloTag® enables live-cell plasma membrane staining, flow cytometry, functional expression, and de-orphaning of recombinant odorant receptors.

Noe F, Frey T, Fiedler J, Geithe C, Nowak B, Krautwurst D.

J Biol Methods. 2017 Nov 3;4(4):e81. doi: 10.14440/jbm.2017.206. eCollection 2017.

7.

Structural determinants of a conserved enantiomer-selective carvone binding pocket in the human odorant receptor OR1A1.

Geithe C, Protze J, Kreuchwig F, Krause G, Krautwurst D.

Cell Mol Life Sci. 2017 Nov;74(22):4209-4229. doi: 10.1007/s00018-017-2576-z. Epub 2017 Jun 27.

PMID:
28656349
8.

OR2M3: A Highly Specific and Narrowly Tuned Human Odorant Receptor for the Sensitive Detection of Onion Key Food Odorant 3-Mercapto-2-methylpentan-1-ol.

Noe F, Polster J, Geithe C, Kotthoff M, Schieberle P, Krautwurst D.

Chem Senses. 2017 Mar 1;42(3):195-210. doi: 10.1093/chemse/bjw118.

PMID:
27916748
9.

The Broadly Tuned Odorant Receptor OR1A1 is Highly Selective for 3-Methyl-2,4-nonanedione, a Key Food Odorant in Aged Wines, Tea, and Other Foods.

Geithe C, Noe F, Kreissl J, Krautwurst D.

Chem Senses. 2017 Mar 1;42(3):181-193. doi: 10.1093/chemse/bjw117.

PMID:
27916747
10.

TRPC6 G757D Loss-of-Function Mutation Associates with FSGS.

Riehle M, Büscher AK, Gohlke BO, Kaßmann M, Kolatsi-Joannou M, Bräsen JH, Nagel M, Becker JU, Winyard P, Hoyer PF, Preissner R, Krautwurst D, Gollasch M, Weber S, Harteneck C.

J Am Soc Nephrol. 2016 Sep;27(9):2771-83. doi: 10.1681/ASN.2015030318. Epub 2016 Feb 18.

11.

A Review of Michael Stoddart.

Krautwurst D, Krautwurst T.

Chem Senses. 2016 Jun;41(5):473-4. doi: 10.1093/chemse/bjw004. Epub 2016 Feb 1. Review. No abstract available.

PMID:
26839358
12.

A Butter Aroma Recombinate Activates Human Class-I Odorant Receptors.

Geithe C, Andersen G, Malki A, Krautwurst D.

J Agric Food Chem. 2015 Nov 4;63(43):9410-20. doi: 10.1021/acs.jafc.5b01884. Epub 2015 Oct 15.

PMID:
26451762
13.

Class I odorant receptors, TAS1R and TAS2R taste receptors, are markers for subpopulations of circulating leukocytes.

Malki A, Fiedler J, Fricke K, Ballweg I, Pfaffl MW, Krautwurst D.

J Leukoc Biol. 2015 Mar;97(3):533-45. doi: 10.1189/jlb.2A0714-331RR. Epub 2015 Jan 26.

14.

Nature's chemical signatures in human olfaction: a foodborne perspective for future biotechnology.

Dunkel A, Steinhaus M, Kotthoff M, Nowak B, Krautwurst D, Schieberle P, Hofmann T.

Angew Chem Int Ed Engl. 2014 Jul 7;53(28):7124-43. doi: 10.1002/anie.201309508. Epub 2014 Jun 18. Review.

PMID:
24939725
15.

A hit map-based statistical method to predict best ligands for orphan olfactory receptors: natural key odorants versus "lock picks".

Krautwurst D, Kotthoff M.

Methods Mol Biol. 2013;1003:85-97. doi: 10.1007/978-1-62703-377-0_6.

PMID:
23585035
16.

Biogenic amines activate blood leukocytes via trace amine-associated receptors TAAR1 and TAAR2.

Babusyte A, Kotthoff M, Fiedler J, Krautwurst D.

J Leukoc Biol. 2013 Mar;93(3):387-94. doi: 10.1189/jlb.0912433. Epub 2013 Jan 11.

PMID:
23315425
17.

Synthetic modulators of TRP channel activity.

Harteneck C, Klose C, Krautwurst D.

Adv Exp Med Biol. 2011;704:87-106. doi: 10.1007/978-94-007-0265-3_4. Review.

PMID:
21290290
18.

Fenamates as TRP channel blockers: mefenamic acid selectively blocks TRPM3.

Klose C, Straub I, Riehle M, Ranta F, Krautwurst D, Ullrich S, Meyerhof W, Harteneck C.

Br J Pharmacol. 2011 Apr;162(8):1757-69. doi: 10.1111/j.1476-5381.2010.01186.x.

19.

Human olfactory receptor families and their odorants.

Krautwurst D.

Chem Biodivers. 2008 Jun;5(6):842-52. doi: 10.1002/cbdv.200890099.

PMID:
18618407
20.

The human vomeronasal type-1 receptor family--detection of volatiles and cAMP signaling in HeLa/Olf cells.

Shirokova E, Raguse JD, Meyerhof W, Krautwurst D.

FASEB J. 2008 May;22(5):1416-25. Epub 2007 Dec 20.

PMID:
18096815
21.

Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2.

Schmiedeberg K, Shirokova E, Weber HP, Schilling B, Meyerhof W, Krautwurst D.

J Struct Biol. 2007 Sep;159(3):400-12. Epub 2007 May 25.

PMID:
17601748
22.

Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels.

Huber TB, Schermer B, Müller RU, Höhne M, Bartram M, Calixto A, Hagmann H, Reinhardt C, Koos F, Kunzelmann K, Shirokova E, Krautwurst D, Harteneck C, Simons M, Pavenstädt H, Kerjaschki D, Thiele C, Walz G, Chalfie M, Benzing T.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17079-86. Epub 2006 Nov 1.

23.

Receptor-induced activation of Drosophila TRP gamma by polyunsaturated fatty acids.

Jörs S, Kazanski V, Foik A, Krautwurst D, Harteneck C.

J Biol Chem. 2006 Oct 6;281(40):29693-702. Epub 2006 Aug 10.

24.

Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants.

Shirokova E, Schmiedeberg K, Bedner P, Niessen H, Willecke K, Raguse JD, Meyerhof W, Krautwurst D.

J Biol Chem. 2005 Mar 25;280(12):11807-15. Epub 2004 Dec 14.

25.

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.

Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W.

Nat Genet. 2002 Nov;32(3):397-401. Epub 2002 Oct 15.

PMID:
12379855
26.
27.
28.

Imidazoline binding sites and signal transduction pathways.

Musgrave IF, Krautwurst D, Schultz G.

Clin Exp Pharmacol Physiol. 1996 Oct-Nov;23(10-11):990-4. Review.

PMID:
8911748
29.
31.

Clonidine and cirazoline inhibit activation of nicotinic channels in PC-12 cells.

Musgrave IF, Krautwurst D, Hescheler J, Schultz G.

Ann N Y Acad Sci. 1995 Jul 12;763:272-82.

PMID:
7545885
32.

The isoquinoline derivative LOE 908 selectively blocks vasopressin-activated nonselective cation currents in A7r5 aortic smooth muscle cells.

Krautwurst D, Degtiar VE, Schultz G, Hescheler J.

Naunyn Schmiedebergs Arch Pharmacol. 1994 Mar;349(3):301-7.

PMID:
7516040
33.
34.

Novel potent inhibitor of receptor-activated nonselective cation currents in HL-60 cells.

Krautwurst D, Hescheler J, Arndts D, Lösel W, Hammer R, Schultz G.

Mol Pharmacol. 1993 May;43(5):655-9.

PMID:
7684814
35.

Major role of dihydropyridine-sensitive Ca2+ channels in Ca(2+)-induced calcitonin secretion.

Scherübl H, Kleppisch T, Zink A, Raue F, Krautwurst D, Hescheler J.

Am J Physiol. 1993 Mar;264(3 Pt 1):E354-60.

PMID:
8384790
36.

Dihydropyridine binding and Ca(2+)-channel characterization in clonal calcitonin-secreting cells.

Krautwurst D, Scherübl H, Kleppisch T, Hescheler J, Schultz G.

Biochem J. 1993 Feb 1;289 ( Pt 3):659-65.

38.

Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart.

Hescheler J, Meyer R, Plant S, Krautwurst D, Rosenthal W, Schultz G.

Circ Res. 1991 Dec;69(6):1476-86.

PMID:
1683272
39.

Calcium currents of neuroblastoma x glioma hybrid cells after cultivation with dibutyryl cyclic AMP and nickel.

Eckert R, Hescheler J, Krautwurst D, Schultz G, Trautwein W.

Pflugers Arch. 1990 Nov;417(3):329-35.

PMID:
2177186

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