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Items: 1 to 50 of 53

1.

PKR-like endoplasmic reticulum kinase (PERK) activation following brain ischemia is independent of unfolded nascent proteins.

Sanderson TH, Deogracias MP, Nangia KK, Wang J, Krause GS, Kumar R.

Neuroscience. 2010 Sep 1;169(3):1307-14. doi: 10.1016/j.neuroscience.2010.05.076. Epub 2010 Jun 9.

PMID:
20538047
2.

Insulin activates the PI3K-Akt survival pathway in vulnerable neurons following global brain ischemia.

Sanderson TH, Kumar R, Murariu-Dobrin AC, Page AB, Krause GS, Sullivan JM.

Neurol Res. 2009 Nov;31(9):947-58. doi: 10.1179/174313209X382449. Epub 2009 Feb 6.

PMID:
19203442
3.

Insulin blocks cytochrome c release in the reperfused brain through PI3-K signaling and by promoting Bax/Bcl-XL binding.

Sanderson TH, Kumar R, Sullivan JM, Krause GS.

J Neurochem. 2008 Aug;106(3):1248-58. doi: 10.1111/j.1471-4159.2008.05473.x. Epub 2008 Jun 2.

4.

Gene expression analysis of the development of congenital hydrocephalus in the H-Tx rat.

Miller JM, Kumar R, McAllister JP 2nd, Krause GS.

Brain Res. 2006 Feb 23;1075(1):36-47. Epub 2006 Feb 15.

PMID:
16469303
5.

PERK is responsible for the increased phosphorylation of eIF2alpha and the severe inhibition of protein synthesis after transient global brain ischemia.

Owen CR, Kumar R, Zhang P, McGrath BC, Cavener DR, Krause GS.

J Neurochem. 2005 Sep;94(5):1235-42. Epub 2005 Jul 5.

6.

Status report: Development of emergency medicine research since the Macy Report.

Pollack CV Jr, Hollander JE, O'Neil BJ, Neumar RW, Summers R, Camargo CA Jr, Younger JG, Callaway CW, Gallagher EJ, Kellermann AL, Krause GS, Schafermeyer RW, Sloan E, Stern S; ACEP Research Committee.

Ann Emerg Med. 2003 Jul;42(1):66-80. Review.

PMID:
12827125
7.

Persistent eIF2alpha(P) is colocalized with cytoplasmic cytochrome c in vulnerable hippocampal neurons after 4 hours of reperfusion following 10-minute complete brain ischemia.

Page AB, Owen CR, Kumar R, Miller JM, Rafols JA, White BC, DeGracia DJ, Krause GS.

Acta Neuropathol. 2003 Jul;106(1):8-16. Epub 2003 Apr 9.

PMID:
12687390
8.

Dysfunction of the unfolded protein response during global brain ischemia and reperfusion.

Kumar R, Krause GS, Yoshida H, Mori K, DeGracia DJ.

J Cereb Blood Flow Metab. 2003 Apr;23(4):462-71.

PMID:
12679723
9.

Re: Henderson, Academic productivity in emergency medicine, The Journal of Emergency Medicine, July 2001.

Krause GS.

J Emerg Med. 2002 Apr;22(3):301; author reply 301-2. No abstract available.

PMID:
11932101
10.

Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death.

DeGracia DJ, Kumar R, Owen CR, Krause GS, White BC.

J Cereb Blood Flow Metab. 2002 Feb;22(2):127-41. Review.

PMID:
11823711
11.

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

Kumar R, Azam S, Sullivan JM, Owen C, Cavener DR, Zhang P, Ron D, Harding HP, Chen JJ, Han A, White BC, Krause GS, DeGracia DJ.

J Neurochem. 2001 Jun;77(5):1418-21.

12.

Brain ischemia and reperfusion: molecular mechanisms of neuronal injury.

White BC, Sullivan JM, DeGracia DJ, O'Neil BJ, Neumar RW, Grossman LI, Rafols JA, Krause GS.

J Neurol Sci. 2000 Oct 1;179(S 1-2):1-33. Review.

PMID:
11054482
13.

Insulin induces dephosphorylation of eukaryotic initiation factor 2alpha and restores protein synthesis in vulnerable hippocampal neurons after transient brain ischemia.

Sullivan JM, Alousi SS, Hikade KR, Bahu NJ, Rafols JA, Krause GS, White BC.

J Cereb Blood Flow Metab. 1999 Sep;19(9):1010-9.

PMID:
10478653
14.

Eukaryotic initiation factor 2alpha kinase and phosphatase activity during postischemic brain reperfusion.

DeGracia DJ, Adamczyk S, Folbe AJ, Konkoly LL, Pittman JE, Neumar RW, Sullivan JM, Scheuner D, Kaufman RJ, White BC, Krause GS.

Exp Neurol. 1999 Feb;155(2):221-7.

PMID:
10072297
15.

Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation.

Frerichs KU, Smith CB, Brenner M, DeGracia DJ, Krause GS, Marrone L, Dever TE, Hallenbeck JM.

Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14511-6.

16.

Calpain mediates eukaryotic initiation factor 4G degradation during global brain ischemia.

Neumar RW, DeGracia DJ, Konkoly LL, Khoury JI, White BC, Krause GS.

J Cereb Blood Flow Metab. 1998 Aug;18(8):876-81.

PMID:
9701348
17.

Effect of brain ischemia and reperfusion on the localization of phosphorylated eukaryotic initiation factor 2 alpha.

DeGracia DJ, Sullivan JM, Neumar RW, Alousi SS, Hikade KR, Pittman JE, White BC, Rafols JA, Krause GS.

J Cereb Blood Flow Metab. 1997 Dec;17(12):1291-302.

PMID:
9397028
18.
19.

Global brain ischemia and reperfusion.

White BC, Grossman LI, O'Neil BJ, DeGracia DJ, Neumar RW, Rafols JA, Krause GS.

Ann Emerg Med. 1996 May;27(5):588-94. Review.

PMID:
8629779
20.

Brain mu-calpain autolysis during global cerebral ischemia.

Neumar RW, Hagle SM, DeGracia DJ, Krause GS, White BC.

J Neurochem. 1996 Jan;66(1):421-4.

PMID:
8522983
21.

Eukaryotic initiation factor 4E degradation during brain ischemia.

Neumar RW, DeGracia DJ, White BC, McDermott PJ, Evans DR, Krause GS.

J Neurochem. 1995 Sep;65(3):1391-4.

PMID:
7643117
22.

Nuclear-envelope nucleoside triphosphatase kinetics and mRNA transport following brain ischemia and reperfusion.

Tiffany BR, White BC, Krause GS.

Ann Emerg Med. 1995 Jun;25(6):809-17. Review.

PMID:
7755206
23.

Global brain ischemia and reperfusion: Golgi apparatus ultrastructure in neurons selectively vulnerable to death.

Rafols JA, Daya AM, O'Neil BJ, Krause GS, Neumar RW, White BC.

Acta Neuropathol. 1995;90(1):17-30.

PMID:
7572075
24.

Insulin induces tyrosine phosphorylation of a 90-kDa protein during postischemic brain reperfusion.

DeGracia DJ, O'Neil BJ, White BC, Tiffany BR, Krause GS, Grossman LI, Grunberger G.

Exp Neurol. 1993 Dec;124(2):351-6.

PMID:
7507063
25.

Brain injury by global ischemia and reperfusion: a theoretical perspective on membrane damage and repair.

White BC, Grossman LI, Krause GS.

Neurology. 1993 Sep;43(9):1656-65. Review. No abstract available.

PMID:
8414008
26.

Potential role of growth factors in global brain ischemia and reperfusion. Observation of insulin-driven tyrosine phosphorylation of a 90-kDa protein during reperfusion.

White BC, Krause GS, O'Neil BJ, DeGracia DJ, Tiffany BR, Grossman LI, Grunberger G.

Ann N Y Acad Sci. 1993 Aug 27;692:281-3. No abstract available.

PMID:
7692794
27.

Brain injury and repair mechanisms: the potential for pharmacologic therapy in closed-head trauma.

White BC, Krause GS.

Ann Emerg Med. 1993 Jun;22(6):970-9. Review.

PMID:
8503535
28.

Suppression of protein synthesis in the reperfused brain.

Krause GS, Tiffany BR.

Stroke. 1993 May;24(5):747-55; discussion 755-6. Review.

PMID:
8488532
29.

Studies of the protein synthesis system in the brain cortex during global ischemia and reperfusion.

DeGracia DJ, O'Neil BJ, Frisch C, Krause GS, Skjaerlund JM, White BC, Grossman LI.

Resuscitation. 1993 Apr;25(2):161-70.

PMID:
8493403
30.

Fluorescent histochemical localization of lipid peroxidation during brain reperfusion following cardiac arrest.

White BC, Daya A, DeGracia DJ, O'Neil BJ, Skjaerlund JM, Trumble S, Krause GS, Rafols JA.

Acta Neuropathol. 1993;86(1):1-9.

PMID:
7690514
31.

Brain mitochondrial DNA is not damaged by prolonged cardiac arrest or reperfusion.

White BC, Tribhuwan RC, Vander Laan DJ, DeGracia DJ, Krause GS, Grossman LI.

J Neurochem. 1992 May;58(5):1716-22.

PMID:
1560228
32.

Assessment of free radical-induced damage in brain proteins after ischemia and reperfusion.

Krause GS, DeGracia DJ, Skjaerlund JM, O'Neil BJ.

Resuscitation. 1992 Feb;23(1):59-69.

PMID:
1315070
33.

The effect of EMHP on post-cardiac arrest survival of rats.

Skjaerlund JM, Krause GS, Feldman DM, O'Neil BJ, White BC.

Resuscitation. 1991 Oct;22(2):139-49.

PMID:
1661019
34.

Incidence of cocaine-associated rhabdomyolysis.

Welch RD, Todd K, Krause GS.

Ann Emerg Med. 1991 Feb;20(2):154-7.

PMID:
1996798
35.

Thymine glycols and pyrimidine dimers in brain DNA during post-ischemic reperfusion.

O'Neil BJ, Krause GS, White BC.

Resuscitation. 1991 Feb;21(1):41-55.

PMID:
1852064
36.

Brain nuclear DNA survives cardiac arrest and reperfusion.

White BC, DeGracia DJ, Krause GS, Skjaerlund JM, O'Neil BJ, Grossman LI.

Free Radic Biol Med. 1991;10(2):125-35.

PMID:
1849865
37.

A basic resource guide for emergency medicine research.

Whitley TW, Spivey WH, Abramson NS, Angelos MG, Barsan WG, Bradley K, Brown CG, Cordell WH, Dart RC, Krause GS, et al.

Ann Emerg Med. 1990 Nov;19(11):1306-9. No abstract available.

PMID:
2240728
38.

Effect on biochemical markers of brain injury of therapy with deferoxamine or superoxide dismutase following cardiac arrest.

White BC, Nayini NR, Krause GS, Aust SD, March GG, Bicknell JS 4th, Goosmann M.

Am J Emerg Med. 1988 Nov;6(6):569-76.

PMID:
3178948
39.

A quantitative morphological assessment of the effect of lidoflazine and deferoxamine therapy on global brain ischaemia.

Kumar K, White BC, Krause GS, Indrieri RJ, Evans AT, Hoehner TJ, Garritano AM, Koestner A.

Neurol Res. 1988 Sep;10(3):136-40.

PMID:
2905775
40.

Brain cell death following ischemia and reperfusion: a proposed biochemical sequence.

Krause GS, White BC, Aust SD, Nayini NR, Kumar K.

Crit Care Med. 1988 Jul;16(7):714-26. Review. No abstract available.

PMID:
3286122
41.

Natural course of iron delocalization and lipid peroxidation during the first eight hours following a 15-minute cardiac arrest in dogs.

Krause GS, Nayini NR, White BC, Hoenher TJ, Garritano AM, O'Neil BJ, Aust SD.

Ann Emerg Med. 1987 Nov;16(11):1200-5.

PMID:
3662177
42.

Brain cortex tissue Ca, Mg, Fe, Na, and K following resuscitation from cardiac arrest in dogs.

Hoehner TJ, Garritano AM, Dilorenzo RA, O'Neil BJ, Kumar K, Koehler J, Nayini NR, Huang RR, Krause GS, Aust SD, et al.

Am J Emerg Med. 1987 Jan;5(1):19-23.

PMID:
3814277
43.

Ultrastructural and ionic studies in global ischemic dog brain.

Kumar K, Goosmann M, Krause GS, Nayini NR, Estrada R, Hoehner TJ, White BC, Koestner A.

Acta Neuropathol. 1987;73(4):393-9.

PMID:
3618131
44.

Myocardial tissue iron delocalization and evidence for lipid peroxidation after two hours of ischemia.

Holt S, Gunderson M, Joyce K, Nayini NR, Eyster GF, Garitano AM, Zonia C, Krause GS, Aust SD, White BC.

Ann Emerg Med. 1986 Oct;15(10):1155-9.

PMID:
3752645
45.

Brain iron delocalization and lipid peroxidation following cardiac arrest.

Komara JS, Nayini NR, Bialick HA, Indrieri RJ, Evans AT, Garritano AM, Hoehner TJ, Jacobs WA, Huang RR, Krause GS, et al.

Ann Emerg Med. 1986 Apr;15(4):384-9.

PMID:
3954169
46.

Ischemia, resuscitation, and reperfusion: mechanisms of tissue injury and prospects for protection.

Krause GS, Kumar K, White BC, Aust SD, Wiegenstein JG.

Am Heart J. 1986 Apr;111(4):768-80. Review.

PMID:
3513507
47.

Cardiac arrest and resuscitation: brain iron delocalization during reperfusion.

Krause GS, Joyce KM, Nayini NR, Zonia CL, Garritano AM, Hoehner TJ, Evans AT, Indreri RJ, Huang RR, Aust SD, et al.

Ann Emerg Med. 1985 Nov;14(11):1037-43.

PMID:
4051267
48.

Postischemic tissue injury by iron-mediated free radical lipid peroxidation.

White BC, Krause GS, Aust SD, Eyster GE.

Ann Emerg Med. 1985 Aug;14(8):804-9.

PMID:
4025973
49.

Cerebral cortical perfusion during and following resuscitation from cardiac arrest in dogs.

White BC, Winegar CD, Jackson RE, Joyce KM, Vigor DN, Hoehner TJ, Krause GS, Wilson RF.

Am J Emerg Med. 1983 Sep;1(2):128-38.

PMID:
6680612
50.

Calcium blockers in cerebral resuscitation.

White BC, Winegar CD, Wilson RF, Krause GS.

J Trauma. 1983 Sep;23(9):788-94.

PMID:
6620432

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