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Items: 1 to 50 of 84

1.

CGRP as the target of new migraine therapies - successful translation from bench to clinic.

Edvinsson L, Haanes KA, Warfvinge K, Krause DN.

Nat Rev Neurol. 2018 Jun;14(6):338-350. doi: 10.1038/s41582-018-0003-1. Review.

PMID:
29691490
2.

U0126 attenuates cerebral vasoconstriction and improves long-term neurologic outcome after stroke in female rats.

Ahnstedt H, Mostajeran M, Blixt FW, Warfvinge K, Ansar S, Krause DN, Edvinsson L.

J Cereb Blood Flow Metab. 2015 Mar;35(3):454-60. doi: 10.1038/jcbfm.2014.217. Epub 2014 Dec 10.

3.

Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection.

Kemper MF, Stirone C, Krause DN, Duckles SP, Procaccio V.

Eur J Pharmacol. 2014 Jan 15;723:322-9. doi: 10.1016/j.ejphar.2013.11.009. Epub 2013 Nov 22.

4.

Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries.

Ahnstedt H, Cao L, Krause DN, Warfvinge K, Säveland H, Nilsson OG, Edvinsson L.

PLoS One. 2013 Apr 29;8(4):e62698. doi: 10.1371/journal.pone.0062698. Print 2013.

5.

Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms.

Kemper MF, Zhao Y, Duckles SP, Krause DN.

J Cereb Blood Flow Metab. 2013 Jan;33(1):122-8. doi: 10.1038/jcbfm.2012.159. Epub 2012 Oct 24.

6.

17β-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen-glucose deprivation/reperfusion.

Guo J, Duckles SP, Weiss JH, Li X, Krause DN.

Free Radic Biol Med. 2012 Jun 1-15;52(11-12):2151-60. doi: 10.1016/j.freeradbiomed.2012.03.005. Epub 2012 Apr 19.

7.

Local oestrogenic/androgenic balance in the cerebral vasculature.

Krause DN, Duckles SP, Gonzales RJ.

Acta Physiol (Oxf). 2011 Sep;203(1):181-6. doi: 10.1111/j.1748-1716.2011.02323.x. Epub 2011 May 27. Review.

8.

[Mechanism of estrogen-mediated neuroprotection: regulation of mitochondrial function].

Guo JB, Tie L, Krause DN, Duckles SP, Li XJ.

Sheng Li Ke Xue Jin Zhan. 2010 Jun;41(3):165-70. Review. Chinese.

PMID:
21416974
9.

Mechanisms of cerebrovascular protection: oestrogen, inflammation and mitochondria.

Duckles SP, Krause DN.

Acta Physiol (Oxf). 2011 Sep;203(1):149-54. doi: 10.1111/j.1748-1716.2010.02184.x. Epub 2010 Oct 11. Review.

10.

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors.

Dubocovich ML, Delagrange P, Krause DN, Sugden D, Cardinali DP, Olcese J.

Pharmacol Rev. 2010 Sep;62(3):343-80. doi: 10.1124/pr.110.002832. Epub 2010 Jul 6.

11.

Estrogen-receptor-mediated protection of cerebral endothelial cell viability and mitochondrial function after ischemic insult in vitro.

Guo J, Krause DN, Horne J, Weiss JH, Li X, Duckles SP.

J Cereb Blood Flow Metab. 2010 Mar;30(3):545-54. doi: 10.1038/jcbfm.2009.226. Epub 2009 Oct 28.

12.

Dihydrotestosterone stimulates cerebrovascular inflammation through NFkappaB, modulating contractile function.

Gonzales RJ, Duckles SP, Krause DN.

J Cereb Blood Flow Metab. 2009 Feb;29(2):244-53. doi: 10.1038/jcbfm.2008.115. Epub 2008 Oct 22.

13.

Mitochondrial effects of estrogen are mediated by estrogen receptor alpha in brain endothelial cells.

Razmara A, Sunday L, Stirone C, Wang XB, Krause DN, Duckles SP, Procaccio V.

J Pharmacol Exp Ther. 2008 Jun;325(3):782-90. doi: 10.1124/jpet.107.134072. Epub 2008 Mar 19.

14.

Estrogen suppresses brain mitochondrial oxidative stress in female and male rats.

Razmara A, Duckles SP, Krause DN, Procaccio V.

Brain Res. 2007 Oct 24;1176:71-81. Epub 2007 Aug 24.

15.

Cerebrovascular effects of oestrogen: multiplicity of action.

Duckles SP, Krause DN.

Clin Exp Pharmacol Physiol. 2007 Aug;34(8):801-8. Review.

PMID:
17600562
16.

Androgenic/estrogenic balance in the male rat cerebral circulation: metabolic enzymes and sex steroid receptors.

Gonzales RJ, Ansar S, Duckles SP, Krause DN.

J Cereb Blood Flow Metab. 2007 Nov;27(11):1841-52. Epub 2007 Apr 4.

17.

Age alters cerebrovascular inflammation and effects of estrogen.

Sunday L, Osuna C, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2333-40. Epub 2007 Jan 5.

18.

Influence of sex steroid hormones on cerebrovascular function.

Krause DN, Duckles SP, Pelligrino DA.

J Appl Physiol (1985). 2006 Oct;101(4):1252-61. Epub 2006 Jun 22. Review.

19.

Estrogen and mitochondria: a new paradigm for vascular protection?

Duckles SP, Krause DN, Stirone C, Procaccio V.

Mol Interv. 2006 Feb;6(1):26-35. Review.

PMID:
16507748
20.

Estrogen and progestagens differentially modulate vascular proinflammatory factors.

Sunday L, Tran MM, Krause DN, Duckles SP.

Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E261-7. Epub 2006 Feb 21.

21.

Testosterone augments endotoxin-mediated cerebrovascular inflammation in male rats.

Razmara A, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2005 Nov;289(5):H1843-50. Epub 2005 Jul 8.

22.

Estrogen increases mitochondrial efficiency and reduces oxidative stress in cerebral blood vessels.

Stirone C, Duckles SP, Krause DN, Procaccio V.

Mol Pharmacol. 2005 Oct;68(4):959-65. Epub 2005 Jun 30.

23.

Testosterone treatment increases thromboxane function in rat cerebral arteries.

Gonzales RJ, Ghaffari AA, Duckles SP, Krause DN.

Am J Physiol Heart Circ Physiol. 2005 Aug;289(2):H578-85. Epub 2005 Mar 11. Erratum in: Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2754.

24.

Estrogen receptor activation of phosphoinositide-3 kinase, akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects.

Stirone C, Boroujerdi A, Duckles SP, Krause DN.

Mol Pharmacol. 2005 Jan;67(1):105-13. Epub 2004 Oct 20.

25.

Effect of estrogen on cerebrovascular prostaglandins is amplified in mice with dysfunctional NOS.

Li X, Geary GG, Gonzales RJ, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H588-94.

26.

Estrogen suppresses IL-1beta-mediated induction of COX-2 pathway in rat cerebral blood vessels.

Ospina JA, Brevig HN, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2004 May;286(5):H2010-9. Epub 2003 Dec 18.

27.
28.

Testosterone suppresses endothelium-dependent dilation of rat middle cerebral arteries.

Gonzales RJ, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H552-60. Epub 2003 Oct 9.

29.

17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation.

Ospina JA, Duckles SP, Krause DN.

Am J Physiol Heart Circ Physiol. 2003 Jul;285(1):H241-50. Epub 2003 Mar 13.

30.

Vascular neuroeffector mechanisms: the next 30 years.

Krause DN, Purdy RE, Pearce WJ, Duckles SP.

Trends Pharmacol Sci. 2002 Dec;23(12):541-2.

PMID:
12457765
31.

Regional differences in the effect of oestrogen on vascular tone in isolated rabbit arteries.

Saetrum Opgaard O, Duckles SP, Krause DN.

Pharmacol Toxicol. 2002 Aug;91(2):77-82.

PMID:
12420796
32.

Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen.

Stirone C, Duckles SP, Krause DN.

Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E184-92. Epub 2002 Sep 11.

33.

MT(2) melatonin receptors are present and functional in rat caudal artery.

Masana MI, Doolen S, Ersahin C, Al-Ghoul WM, Duckles SP, Dubocovich ML, Krause DN.

J Pharmacol Exp Ther. 2002 Sep;302(3):1295-302.

34.

Male-female differences in the relative contribution of endothelial vasodilators released by rat tail artery.

Pak KJ, Geary GG, Duckles SP, Krause DN.

Life Sci. 2002 Aug 23;71(14):1633-42.

PMID:
12137910
36.
37.

Selected contribution: cerebrovascular nos and cyclooxygenase are unaffected by estrogen in mice lacking estrogen receptor-alpha.

Geary GG, McNeill AM, Ospina JA, Krause DN, Korach KS, Duckles SP.

J Appl Physiol (1985). 2001 Nov;91(5):2391-9; discussion 2389-90.

38.

Human urotensin II mediates vasoconstriction via an increase in inositol phosphates.

Saetrum Opgaard O, Nothacker H, Ehlert FJ, Krause DN.

Eur J Pharmacol. 2000 Oct 13;406(2):265-71.

PMID:
11020490
39.

Gonadal hormones affect diameter of male rat cerebral arteries through endothelium-dependent mechanisms.

Geary GG, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2000 Aug;279(2):H610-8.

40.

Estrogen reduces mouse cerebral artery tone through endothelial NOS- and cyclooxygenase-dependent mechanisms.

Geary GG, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2000 Aug;279(2):H511-9.

41.

Melatonin and cardiovascular function.

Krause DN, Geary GG, Doolen S, Duckles SP.

Adv Exp Med Biol. 1999;460:299-310. Review. No abstract available.

PMID:
10810525
42.

Chronic estrogen treatment increases levels of endothelial nitric oxide synthase protein in rat cerebral microvessels.

McNeill AM, Kim N, Duckles SP, Krause DN, Kontos HA.

Stroke. 1999 Oct;30(10):2186-90.

PMID:
10512927
43.

Postjunctional alpha2-adrenoceptors in the rat tail artery: effect of sex and castration.

Chen DC, Duckles SP, Krause DN.

Eur J Pharmacol. 1999 May 21;372(3):247-52.

PMID:
10395019
44.

Estradiol modulates vascular response to melatonin in rat caudal artery.

Doolen S, Krause DN, Duckles SP.

Am J Physiol. 1999 Apr;276(4 Pt 2):H1281-8.

PMID:
10199853
45.

Gender difference in levels of alpha2-adrenoceptor mRNA in the rat tail artery.

McNeill AM, Leslie FM, Krause DN, Duckles SP.

Eur J Pharmacol. 1999 Feb 5;366(2-3):233-6.

PMID:
10082204
46.

Simulated microgravity increases myogenic tone in rat cerebral arteries.

Geary GG, Krause DN, Purdy RE, Duckles SP.

J Appl Physiol (1985). 1998 Nov;85(5):1615-21.

47.

Effect of simulated microgravity on vascular contractility.

Purdy RE, Duckles SP, Krause DN, Rubera KM, Sara D.

J Appl Physiol (1985). 1998 Oct;85(4):1307-15.

48.

Estrogen reduces myogenic tone through a nitric oxide-dependent mechanism in rat cerebral arteries.

Geary GG, Krause DN, Duckles SP.

Am J Physiol. 1998 Jul;275(1 Pt 2):H292-300.

PMID:
9688926
49.

Effect of melatonin in the rat tail artery: role of K+ channels and endothelial factors.

Geary GG, Duckles SP, Krause DN.

Br J Pharmacol. 1998 Apr;123(8):1533-40.

50.

Melatonin mediates two distinct responses in vascular smooth muscle.

Doolen S, Krause DN, Dubocovich ML, Duckles SP.

Eur J Pharmacol. 1998 Mar 12;345(1):67-9.

PMID:
9593596

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