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Items: 48

1.

Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra.

Ji DX, Yamashiro LH, Chen KJ, Mukaida N, Kramnik I, Darwin KH, Vance RE.

Nat Microbiol. 2019 Oct 14. doi: 10.1038/s41564-019-0578-3. [Epub ahead of print]

PMID:
31611644
2.

Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma.

Carow B, Hauling T, Qian X, Kramnik I, Nilsson M, Rottenberg ME.

Nat Commun. 2019 Apr 23;10(1):1823. doi: 10.1038/s41467-019-09816-4.

3.

Protection of macrophages from intracellular pathogens by miR-182-5p mimic-a gene expression meta-analysis approach.

Gregory DJ, Kramnik I, Kobzik L.

FEBS J. 2018 Jan;285(2):244-260. doi: 10.1111/febs.14348. Epub 2017 Dec 26.

4.

Capacity of Pneumococci to Activate Macrophage Nuclear Factor κB: Influence on Necroptosis and Pneumonia Severity.

Coleman FT, Blahna MT, Kamata H, Yamamoto K, Zabinski MC, Kramnik I, Wilson AA, Kotton DN, Quinton LJ, Jones MR, Pelton SI, Mizgerd JP.

J Infect Dis. 2017 Aug 15;216(4):425-435. doi: 10.1093/infdis/jix159.

5.

New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles.

Coppola M, van Meijgaarden KE, Franken KL, Commandeur S, Dolganov G, Kramnik I, Schoolnik GK, Comas I, Lund O, Prins C, van den Eeden SJ, Korsvold GE, Oftung F, Geluk A, Ottenhoff TH.

Sci Rep. 2016 Nov 28;6:37793. doi: 10.1038/srep37793.

6.

SP110b Controls Host Immunity and Susceptibility to Tuberculosis.

Leu JS, Chen ML, Chang SY, Yu SL, Lin CW, Wang H, Chen WC, Chang CH, Wang JY, Lee LN, Yu CJ, Kramnik I, Yan BS.

Am J Respir Crit Care Med. 2017 Feb 1;195(3):369-382. doi: 10.1164/rccm.201601-0103OC.

7.

Fine-tuning of macrophage activation using synthetic rocaglate derivatives.

Bhattacharya B, Chatterjee S, Devine WG, Kobzik L, Beeler AB, Porco JA Jr, Kramnik I.

Sci Rep. 2016 Apr 18;6:24409. doi: 10.1038/srep24409.

8.

Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies.

Kramnik I, Beamer G.

Semin Immunopathol. 2016 Mar;38(2):221-37. doi: 10.1007/s00281-015-0538-9. Epub 2015 Nov 5. Review.

9.

Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice.

Niazi MK, Dhulekar N, Schmidt D, Major S, Cooper R, Abeijon C, Gatti DM, Kramnik I, Yener B, Gurcan M, Beamer G.

Dis Model Mech. 2015 Sep;8(9):1141-53. doi: 10.1242/dmm.020867. Epub 2015 Jul 23.

10.

Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas.

Irwin SM, Gruppo V, Brooks E, Gilliland J, Scherman M, Reichlen MJ, Leistikow R, Kramnik I, Nuermberger EL, Voskuil MI, Lenaerts AJ.

Antimicrob Agents Chemother. 2014 Jul;58(7):4026-34. doi: 10.1128/AAC.02565-14. Epub 2014 May 5.

11.

The sst1 resistance locus regulates evasion of type I interferon signaling by Chlamydia pneumoniae as a disease tolerance mechanism.

He X, Berland R, Mekasha S, Christensen TG, Alroy J, Kramnik I, Ingalls RR.

PLoS Pathog. 2013;9(8):e1003569. doi: 10.1371/journal.ppat.1003569. Epub 2013 Aug 29.

12.

An unbiased genome-wide Mycobacterium tuberculosis gene expression approach to discover antigens targeted by human T cells expressed during pulmonary infection.

Commandeur S, van Meijgaarden KE, Prins C, Pichugin AV, Dijkman K, van den Eeden SJ, Friggen AH, Franken KL, Dolganov G, Kramnik I, Schoolnik GK, Oftung F, Korsvold GE, Geluk A, Ottenhoff TH.

J Immunol. 2013 Feb 15;190(4):1659-71. doi: 10.4049/jimmunol.1201593. Epub 2013 Jan 14.

13.

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.

Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N.

Nat Immunol. 2013 Feb;14(2):179-85. doi: 10.1038/ni.2509. Epub 2012 Dec 23.

14.

Genetic dissection of pulmonary tuberculosis: implications for drug and vaccine development.

Kramnik I.

Nihon Hansenbyo Gakkai Zasshi. 2012 Apr;81(1-2):13. No abstract available.

PMID:
22586941
15.

Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis.

Driver ER, Ryan GJ, Hoff DR, Irwin SM, Basaraba RJ, Kramnik I, Lenaerts AJ.

Antimicrob Agents Chemother. 2012 Jun;56(6):3181-95. doi: 10.1128/AAC.00217-12. Epub 2012 Apr 2.

16.

The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity.

Yang CS, Rodgers M, Min CK, Lee JS, Kingeter L, Lee JY, Jong A, Kramnik I, Lin X, Jung JU.

Cell Host Microbe. 2012 Mar 15;11(3):277-89. doi: 10.1016/j.chom.2012.01.019.

17.

Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.

Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh B, Zandi E, Yue Z, Kramnik I, Liang C, Jung JU.

Cell Host Microbe. 2012 Mar 15;11(3):264-76. doi: 10.1016/j.chom.2012.01.018.

18.

Genome-wide RNAi screen in IFN-γ-treated human macrophages identifies genes mediating resistance to the intracellular pathogen Francisella tularensis.

Zhou H, DeLoid G, Browning E, Gregory DJ, Tan F, Bedugnis AS, Imrich A, Koziel H, Kramnik I, Lu Q, Kobzik L.

PLoS One. 2012;7(2):e31752. doi: 10.1371/journal.pone.0031752. Epub 2012 Feb 16.

19.

Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions.

Harper J, Skerry C, Davis SL, Tasneen R, Weir M, Kramnik I, Bishai WR, Pomper MG, Nuermberger EL, Jain SK.

J Infect Dis. 2012 Feb 15;205(4):595-602. doi: 10.1093/infdis/jir786. Epub 2011 Dec 23.

20.

MYBBP1A: a new Ipr1's binding protein in mice.

Cai L, Pan H, Trzciński K, Thompson CM, Wu Q, Kramnik I.

Mol Biol Rep. 2010 Dec;37(8):3863-8. doi: 10.1007/s11033-010-0042-1. Epub 2010 Mar 11.

21.

An improved empirical bayes approach to estimating differential gene expression in microarray time-course data: BETR (Bayesian Estimation of Temporal Regulation).

Aryee MJ, Gutiérrez-Pabello JA, Kramnik I, Maiti T, Quackenbush J.

BMC Bioinformatics. 2009 Dec 10;10:409. doi: 10.1186/1471-2105-10-409.

22.

Dominant role of the sst1 locus in pathogenesis of necrotizing lung granulomas during chronic tuberculosis infection and reactivation in genetically resistant hosts.

Pichugin AV, Yan BS, Sloutsky A, Kobzik L, Kramnik I.

Am J Pathol. 2009 Jun;174(6):2190-201. doi: 10.2353/ajpath.2009.081075. Epub 2009 May 14.

23.

Man and mouse TB: contradictions and solutions.

Apt A, Kramnik I.

Tuberculosis (Edinb). 2009 May;89(3):195-8. doi: 10.1016/j.tube.2009.02.002. Epub 2009 Apr 2. No abstract available.

24.

Lung carcinogenesis induced by chronic tuberculosis infection: the experimental model and genetic control.

Nalbandian A, Yan BS, Pichugin A, Bronson RT, Kramnik I.

Oncogene. 2009 Apr 30;28(17):1928-38. doi: 10.1038/onc.2009.32. Epub 2009 Mar 30.

PMID:
19330024
25.

Multigenic control of tuberculosis resistance: analysis of a QTL on mouse chromosome 7 and its synergism with sst1.

Sissons J, Yan BS, Pichugin AV, Kirby A, Daly MJ, Kramnik I.

Genes Immun. 2009 Jan;10(1):37-46. doi: 10.1038/gene.2008.68. Epub 2008 Sep 11.

26.
27.

Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon.

Kumar A, Deshane JS, Crossman DK, Bolisetty S, Yan BS, Kramnik I, Agarwal A, Steyn AJ.

J Biol Chem. 2008 Jun 27;283(26):18032-9. doi: 10.1074/jbc.M802274200. Epub 2008 Apr 9.

28.

Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guérin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity.

Yan BS, Pichugin AV, Jobe O, Helming L, Eruslanov EB, Gutiérrez-Pabello JA, Rojas M, Shebzukhov YV, Kobzik L, Kramnik I.

J Immunol. 2007 Nov 15;179(10):6919-32.

29.

Dual-promoter lentiviral system allows inducible expression of noxious proteins in macrophages.

Pan H, Mostoslavsky G, Eruslanov E, Kotton DN, Kramnik I.

J Immunol Methods. 2008 Jan 1;329(1-2):31-44. Epub 2007 Oct 18.

30.

Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa.

Tosh K, Campbell SJ, Fielding K, Sillah J, Bah B, Gustafson P, Manneh K, Lisse I, Sirugo G, Bennett S, Aaby P, McAdam KPWJ, Bah-Sow O, Lienhardt C, Kramnik I, Hill AVS.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10364-10368. doi: 10.1073/pnas.0603340103. Epub 2006 Jun 27.

31.

Genetic architecture of tuberculosis resistance in a mouse model of infection.

Yan BS, Kirby A, Shebzukhov YV, Daly MJ, Kramnik I.

Genes Immun. 2006 Apr;7(3):201-10.

PMID:
16452998
32.

Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production.

Sullivan BM, Jobe O, Lazarevic V, Vasquez K, Bronson R, Glimcher LH, Kramnik I.

J Immunol. 2005 Oct 1;175(7):4593-602.

33.

Ipr1 gene mediates innate immunity to tuberculosis.

Pan H, Yan BS, Rojas M, Shebzukhov YV, Zhou H, Kobzik L, Higgins DE, Daly MJ, Bloom BR, Kramnik I.

Nature. 2005 Apr 7;434(7034):767-72.

34.

The host resistance locus sst1 controls innate immunity to Listeria monocytogenes infection in immunodeficient mice.

Boyartchuk V, Rojas M, Yan BS, Jobe O, Hurt N, Dorfman DM, Higgins DE, Dietrich WF, Kramnik I.

J Immunol. 2004 Oct 15;173(8):5112-20.

35.

Immunity to intracellular pathogens as a complex genetic trait.

Kramnik I, Boyartchuk V.

Curr Opin Microbiol. 2002 Feb;5(1):111-7. Review.

PMID:
11834379
36.

Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis.

Kramnik I, Dietrich WF, Demant P, Bloom BR.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8560-5.

37.

Susceptibility to tuberculosis as a complex genetic trait: analysis using recombinant congenic strains of mice.

Kramnik I, Demant P, Bloom BB.

Novartis Found Symp. 1998;217:120-31; discussion 132-7.

PMID:
9949805
38.

Identification of differentially expressed mRNA in prokaryotic organisms by customized amplification libraries (DECAL): the effect of isoniazid on gene expression in Mycobacterium tuberculosis.

Alland D, Kramnik I, Weisbrod TR, Otsubo L, Cerny R, Miller LP, Jacobs WR Jr, Bloom BR.

Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13227-32.

39.

I-A beta gene expression regulation in macrophages derived from mice susceptible or resistant to infection with M. bovis BCG.

Barrera LF, Kramnik I, Skamene E, Radzioch D.

Mol Immunol. 1997 Mar;34(4):343-55.

PMID:
9244347
40.

Molecular mechanisms of natural resistance to mycobacterial infections.

Radzioch D, Kramnik I, Skamene E.

Circ Shock. 1994 Nov;44(3):115-20.

PMID:
7600634
42.
43.

Distinct H-2 complex control of mortality, and immune responses to tuberculosis infection in virgin and BCG-vaccinated mice.

Apt AS, Avdienko VG, Nikonenko BV, Kramnik IB, Moroz AM, Skamene E.

Clin Exp Immunol. 1993 Nov;94(2):322-9.

44.

Assessment of lymphokine profiles in activated lymphocytes by semiquantitative PCR.

Kramnik I, Skamene E, Radzioch D.

J Immunol Methods. 1993 Jun 18;162(2):143-53.

PMID:
7686197
45.

[The isolation and testing of syngeneic anti-idiotypic antibodies against antimycobacterial monoclonal antibodies].

Avdienko VG, Kramnik IB, Apt AS, Litvinov VI.

Probl Tuberk. 1993;(1):47-50. Russian.

PMID:
7687055
46.

Regulation of T-cell proliferative responses by cells from solid lung tissue of M. tuberculosis-infected mice.

Apt AS, Kramnik IB, Moroz AM.

Immunology. 1991 Jun;73(2):173-9. Erratum in: Immunology 1991 Sep;74(1):174.

47.

[Cellular mechanisms of suppression of T-lymphocyte proliferation by lung cells in experimental tuberculosis].

Kramnik IG, Moroz AM, Apt AS.

Biull Eksp Biol Med. 1990 Aug;110(8):172-6. Russian.

PMID:
1705456
48.

[Suppression of immune response by lung cells in experimental tuberculosis].

Kramnik IB, Apt AS, Moroz AM.

Biull Eksp Biol Med. 1990 Jul;110(7):77-80. Russian.

PMID:
2145988

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