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Items: 1 to 50 of 195

1.

Vaccination With Viral Vectors Expressing Chimeric Hemagglutinin, NP and M1 Antigens Protects Ferrets Against Influenza Virus Challenge.

McMahon M, Asthagiri Arunkumar G, Liu WC, Stadlbauer D, Albrecht RA, Pavot V, Aramouni M, Lambe T, Gilbert SC, Krammer F.

Front Immunol. 2019 Aug 21;10:2005. doi: 10.3389/fimmu.2019.02005. eCollection 2019.

2.

Monoclonal antibody responses after recombinant HA vaccine versus subunit inactivated influenza virus vaccine: a comparative study.

Henry C, Palm AE, Utset HA, Huang M, Ho IY, Zheng NY, Fitzgerald T, Neu KE, Chen YQ, Krammer F, Treanor JJ, Sant AJ, Topham DJ, Wilson PC.

J Virol. 2019 Aug 21. pii: JVI.01150-19. doi: 10.1128/JVI.01150-19. [Epub ahead of print]

PMID:
31434733
3.

Moving from Empirical to Rational Vaccine Design in the 'Omics' Era.

Sharma M, Krammer F, García-Sastre A, Tripathi S.

Vaccines (Basel). 2019 Aug 14;7(3). pii: E89. doi: 10.3390/vaccines7030089. Review.

4.

Comparative Immunogenicity of the 2014-2015 Northern Hemisphere Trivalent IIV and LAIV against Influenza A Viruses in Children.

Ang JC, Wang B, Wang JJF, Zeng PYF, Krammer F, Ward BJ, Russell ML, Loeb M, Miller MS.

Vaccines (Basel). 2019 Aug 12;7(3). pii: E87. doi: 10.3390/vaccines7030087.

5.

The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain.

Wan H, Gao J, Yang H, Yang S, Harvey R, Chen YQ, Zheng NY, Chang J, Carney PJ, Li X, Plant E, Jiang L, Couzens L, Wang C, Strohmeier S, Wu WW, Shen RF, Krammer F, Cipollo JF, Wilson PC, Stevens J, Wan XF, Eichelberger MC, Ye Z.

Nat Microbiol. 2019 Aug 12. doi: 10.1038/s41564-019-0522-6. [Epub ahead of print]

PMID:
31406333
6.

Vaccination with viral vectors expressing NP, M1 and chimeric hemagglutinin induces broad protection against influenza virus challenge in mice.

Asthagiri Arunkumar G, McMahon M, Pavot V, Aramouni M, Ioannou A, Lambe T, Gilbert S, Krammer F.

Vaccine. 2019 Sep 3;37(37):5567-5577. doi: 10.1016/j.vaccine.2019.07.095. Epub 2019 Aug 6.

7.

No evidence of antigenic seniority in hemagglutinin specific antibody responses after adjuvanted pandemic 2009 influenza vaccination.

Madsen A, Azimi L, Tete S, Zhou F, Krammer F, Cox RJ, Jul-Larsen Å.

Vaccine X. 2019 Jun 20;2:100029. doi: 10.1016/j.jvacx.2019.100029. eCollection 2019 Aug 9.

8.

Extending the Stalk Enhances Immunogenicity of the Influenza Virus Neuraminidase.

Broecker F, Zheng A, Suntronwong N, Sun W, Bailey MJ, Krammer F, Palese P.

J Virol. 2019 Aug 28;93(18). pii: e00840-19. doi: 10.1128/JVI.00840-19. Print 2019 Sep 15.

PMID:
31375573
9.

A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains.

Broecker F, Liu STH, Suntronwong N, Sun W, Bailey MJ, Nachbagauer R, Krammer F, Palese P.

NPJ Vaccines. 2019 Jul 19;4:31. doi: 10.1038/s41541-019-0126-4. eCollection 2019.

10.

Pre-existing anti-neuraminidase antibodies are associated with shortened duration of influenza A (H1N1)pdm virus shedding and illness in naturally infected adults.

Maier HE, Nachbagauer R, Kuan G, Ng S, Lopez R, Sanchez N, Stadlbauer D, Gresh L, Schiller A, Rajabhathor A, Ojeda S, Guglia AF, Amanat F, Balmaseda A, Krammer F, Gordon A.

Clin Infect Dis. 2019 Jul 12. pii: ciz639. doi: 10.1093/cid/ciz639. [Epub ahead of print]

PMID:
31300819
11.

Characterization of swine-origin H1N1 canine influenza viruses.

Wang G, Dos Anjos Borges LG, Stadlbauer D, Ramos I, Bermúdez González MC, He J, Ding Y, Wei Z, Ouyang K, Huang W, Simon V, Fernandez-Sesma A, Krammer F, Nelson MI, Chen Y, García-Sastre A.

Emerg Microbes Infect. 2019;8(1):1017-1026. doi: 10.1080/22221751.2019.1637284.

PMID:
31287780
12.

Functional immune response to influenza H1N1 in children and adults after live attenuated influenza virus vaccination.

Islam S, Zhou F, Lartey S, Mohn KGI, Krammer F, Cox RJ, Brokstad KA.

Scand J Immunol. 2019 Oct;90(4):e12801. doi: 10.1111/sji.12801. Epub 2019 Sep 2.

PMID:
31269273
13.

Novel correlates of protection against pandemic H1N1 influenza A virus infection.

Ng S, Nachbagauer R, Balmaseda A, Stadlbauer D, Ojeda S, Patel M, Rajabhathor A, Lopez R, Guglia AF, Sanchez N, Amanat F, Gresh L, Kuan G, Krammer F, Gordon A.

Nat Med. 2019 Jun;25(6):962-967. doi: 10.1038/s41591-019-0463-x. Epub 2019 Jun 3.

PMID:
31160818
14.

An HER2-Displaying Virus-Like Particle Vaccine Protects from Challenge with Mammary Carcinoma Cells in a Mouse Model.

Nika L, Cuadrado-Castano S, Asthagiri Arunkumar G, Grünwald-Gruber C, McMahon M, Koczka K, García-Sastre A, Krammer F, Grabherr R.

Vaccines (Basel). 2019 May 20;7(2). pii: E41. doi: 10.3390/vaccines7020041.

15.

Mucosal Immunity against Neuraminidase Prevents Influenza B Virus Transmission in Guinea Pigs.

McMahon M, Kirkpatrick E, Stadlbauer D, Strohmeier S, Bouvier NM, Krammer F.

MBio. 2019 May 21;10(3). pii: e00560-19. doi: 10.1128/mBio.00560-19.

16.

Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model.

Liu WC, Nachbagauer R, Stadlbauer D, Solórzano A, Berlanda-Scorza F, García-Sastre A, Palese P, Krammer F, Albrecht RA.

Front Immunol. 2019 Apr 10;10:756. doi: 10.3389/fimmu.2019.00756. eCollection 2019.

17.

Dengue and Zika: The Complexities of Being Related.

Krammer F, Lim JK.

Trends Immunol. 2019 Jun;40(6):467-469. doi: 10.1016/j.it.2019.04.008. Epub 2019 May 6.

PMID:
31072687
18.

Chimeric Hemagglutinin-Based Influenza Virus Vaccines Induce Protective Stalk-Specific Humoral Immunity and Cellular Responses in Mice.

Choi A, Bouzya B, Cortés Franco KD, Stadlbauer D, Rajabhathor A, Rouxel RN, Mainil R, Van der Wielen M, Palese P, García-Sastre A, Innis BL, Krammer F, Schotsaert M, Mallett CP, Nachbagauer R.

Immunohorizons. 2019 Apr 1;3(4):133-148. doi: 10.4049/immunohorizons.1900022.

19.

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.

Matsuda K, Huang J, Zhou T, Sheng Z, Kang BH, Ishida E, Griesman T, Stuccio S, Bolkhovitinov L, Wohlbold TJ, Chromikova V, Cagigi A, Leung K, Andrews S, Cheung CSF, Pullano AA, Plyler J, Soto C, Zhang B, Yang Y, Joyce MG, Tsybovsky Y, Wheatley A, Narpala SR, Guo Y, Darko S, Bailer RT, Poole A, Liang CJ, Smith J, Alexander J, Gurwith M, Migueles SA, Koup RA, Golding H, Khurana S, McDermott AB, Shapiro L, Krammer F, Kwong PD, Connors M.

Sci Immunol. 2019 Apr 19;4(34). pii: eaau2710. doi: 10.1126/sciimmunol.aau2710.

PMID:
31004012
20.

20th International Conference on Emerging Infectious Diseases in the Pacific Rim Organized by the United States-Japan Cooperative Medical Sciences Program (USJCMSP).

USJCMSP AIDS, ARI, Cancer, Hepatitis, Immunology and Viral Diseases Panels, Bernabe KG, Lu KT, Handley FG, Griffin DE, Kurane I, Iwamoto A, Gao GF, Krammer F.

Vaccines (Basel). 2019 Apr 2;7(2). pii: E35. doi: 10.3390/vaccines7020035.

21.

Development of Influenza B Universal Vaccine Candidates Using the "Mosaic" Hemagglutinin Approach.

Sun W, Kirkpatrick E, Ermler M, Nachbagauer R, Broecker F, Krammer F, Palese P.

J Virol. 2019 May 29;93(12). pii: e00333-19. doi: 10.1128/JVI.00333-19. Print 2019 Jun 15.

PMID:
30944178
22.

Antibodies Elicited by an NS1-Based Vaccine Protect Mice against Zika Virus.

Bailey MJ, Broecker F, Duehr J, Arumemi F, Krammer F, Palese P, Tan GS.

MBio. 2019 Apr 2;10(2). pii: e02861-18. doi: 10.1128/mBio.02861-18.

23.

Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model.

Amanat F, Meade P, Strohmeier S, Krammer F.

Emerg Microbes Infect. 2019;8(1):155-168. doi: 10.1080/22221751.2018.1564369.

24.

The human antibody response to influenza A virus infection and vaccination.

Krammer F.

Nat Rev Immunol. 2019 Jun;19(6):383-397. doi: 10.1038/s41577-019-0143-6. Review.

PMID:
30837674
25.

Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals.

Henry C, Zheng NY, Huang M, Cabanov A, Rojas KT, Kaur K, Andrews SF, Palm AE, Chen YQ, Li Y, Hoskova K, Utset HA, Vieira MC, Wrammert J, Ahmed R, Holden-Wiltse J, Topham DJ, Treanor JJ, Ertl HC, Schmader KE, Cobey S, Krammer F, Hensley SE, Greenberg H, He XS, Wilson PC.

Cell Host Microbe. 2019 Mar 13;25(3):357-366.e6. doi: 10.1016/j.chom.2019.01.002. Epub 2019 Feb 19.

PMID:
30795982
26.

MHC class II proteins mediate cross-species entry of bat influenza viruses.

Karakus U, Thamamongood T, Ciminski K, Ran W, Günther SC, Pohl MO, Eletto D, Jeney C, Hoffmann D, Reiche S, Schinköthe J, Ulrich R, Wiener J, Hayes MGB, Chang MW, Hunziker A, Yángüez E, Aydillo T, Krammer F, Oderbolz J, Meier M, Oxenius A, Halenius A, Zimmer G, Benner C, Hale BG, García-Sastre A, Beer M, Schwemmle M, Stertz S.

Nature. 2019 Mar;567(7746):109-112. doi: 10.1038/s41586-019-0955-3. Epub 2019 Feb 20.

PMID:
30787439
27.

Fighting influenza through hemagglutinin diversity.

Krammer F.

Nat Immunol. 2019 Mar;20(3):246-247. doi: 10.1038/s41590-019-0317-1. No abstract available.

PMID:
30742079
28.

Dengue Virus Immunity Increases Zika Virus-Induced Damage during Pregnancy.

Brown JA, Singh G, Acklin JA, Lee S, Duehr JE, Chokola AN, Frere JJ, Hoffman KW, Foster GA, Krysztof D, Cadagan R, Jacobs AR, Stramer SL, Krammer F, García-Sastre A, Lim JK.

Immunity. 2019 Mar 19;50(3):751-762.e5. doi: 10.1016/j.immuni.2019.01.005. Epub 2019 Feb 5.

PMID:
30737148
29.

Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus.

Tesini BL, Kanagaiah P, Wang J, Hahn M, Halliley JL, Chaves FA, Nguyen PQT, Nogales A, DeDiego ML, Anderson CS, Ellebedy AH, Strohmeier S, Krammer F, Yang H, Bandyopadhyay S, Ahmed R, Treanor JJ, Martinez-Sobrido L, Golding H, Khurana S, Zand MS, Topham DJ, Sangster MY.

J Virol. 2019 Apr 3;93(8). pii: e00169-19. doi: 10.1128/JVI.00169-19. Print 2019 Apr 15.

PMID:
30728266
30.

Universal Influenza Virus Vaccines That Target the Conserved Hemagglutinin Stalk and Conserved Sites in the Head Domain.

Krammer F, Palese P.

J Infect Dis. 2019 Apr 8;219(Supplement_1):S62-S67. doi: 10.1093/infdis/jiy711.

PMID:
30715353
31.

Broadly Cross-Reactive, Nonneutralizing Antibodies against Influenza B Virus Hemagglutinin Demonstrate Effector Function-Dependent Protection against Lethal Viral Challenge in Mice.

Asthagiri Arunkumar G, Ioannou A, Wohlbold TJ, Meade P, Aslam S, Amanat F, Ayllon J, García-Sastre A, Krammer F.

J Virol. 2019 Mar 5;93(6). pii: e01696-18. doi: 10.1128/JVI.01696-18. Print 2019 Mar 15.

32.

Protein Microarray Analysis of the Specificity and Cross-Reactivity of Influenza Virus Hemagglutinin-Specific Antibodies.

Nakajima R, Supnet M, Jasinskas A, Jain A, Taghavian O, Obiero J, Milton DK, Chen WH, Grantham M, Webby R, Krammer F, Carter D, Felgner PL, Davies DH.

mSphere. 2018 Dec 12;3(6). pii: e00592-18. doi: 10.1128/mSphere.00592-18.

33.

Erratum: Sunwoo, S.-Y. et al. A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies. Vaccines 2018, 6(3), 64.

Sunwoo SY, Schotsaert M, Morozov I, Davis AS, Li Y, Lee J, McDowell C, Meade P, Nachbagauer R, García-Sastre A, Ma W, Krammer F, Richt JA.

Vaccines (Basel). 2018 Nov 27;6(4). pii: E80. doi: 10.3390/vaccines6040080.

34.

Human antibodies targeting Zika virus NS1 provide protection against disease in a mouse model.

Bailey MJ, Duehr J, Dulin H, Broecker F, Brown JA, Arumemi FO, Bermúdez González MC, Leyva-Grado VH, Evans MJ, Simon V, Lim JK, Krammer F, Hai R, Palese P, Tan GS.

Nat Commun. 2018 Nov 1;9(1):4560. doi: 10.1038/s41467-018-07008-0.

35.

Antibody Responses toward the Major Antigenic Sites of Influenza B Virus Hemagglutinin in Mice, Ferrets, and Humans.

Sun W, Kang DS, Zheng A, Liu STH, Broecker F, Simon V, Krammer F, Palese P.

J Virol. 2019 Jan 4;93(2). pii: e01673-18. doi: 10.1128/JVI.01673-18. Print 2019 Jan 15.

36.

A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies.

Sunwoo SY, Schotsaert M, Morozov I, Davis AS, Li Y, Lee J, McDowell C, Meade P, Nachbagauer R, García-Sastre A, Ma W, Krammer F, Richt JA.

Vaccines (Basel). 2018 Sep 14;6(3). pii: E64. doi: 10.3390/vaccines6030064. Erratum in: Vaccines (Basel). 2018 Nov 27;6(4):.

37.

Editorial overview: Tough targets.

Krammer F, Wilson PC.

Curr Opin Immunol. 2018 Aug;53:iv-vi. doi: 10.1016/j.coi.2018.08.005. No abstract available.

PMID:
30220352
38.

Antigenic sites in influenza H1 hemagglutinin display species-specific immunodominance.

Liu STH, Behzadi MA, Sun W, Freyn AW, Liu WC, Broecker F, Albrecht RA, Bouvier NM, Simon V, Nachbagauer R, Krammer F, Palese P.

J Clin Invest. 2018 Nov 1;128(11):4992-4996. doi: 10.1172/JCI122895. Epub 2018 Oct 8.

39.

Assessment of Influenza Virus Hemagglutinin Stalk-Specific Antibody Responses.

Liu WC, Nachbagauer R, Krammer F, Albrecht RA.

Methods Mol Biol. 2018;1836:487-511. doi: 10.1007/978-1-4939-8678-1_23.

PMID:
30151588
40.

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies.

Pardi N, Parkhouse K, Kirkpatrick E, McMahon M, Zost SJ, Mui BL, Tam YK, Karikó K, Barbosa CJ, Madden TD, Hope MJ, Krammer F, Hensley SE, Weissman D.

Nat Commun. 2018 Aug 22;9(1):3361. doi: 10.1038/s41467-018-05482-0.

41.

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.

Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE Jr, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM; Viral Hemorrhagic Fever Immunotherapeutic Consortium.

Cell. 2018 Aug 9;174(4):938-952.e13. doi: 10.1016/j.cell.2018.07.033.

42.

Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice.

Broecker F, Liu STH, Sun W, Krammer F, Simon V, Palese P.

J Virol. 2018 Sep 26;92(20). pii: e01100-18. doi: 10.1128/JVI.01100-18. Print 2018 Oct 15.

43.
44.

The influenza virus hemagglutinin head evolves faster than the stalk domain.

Kirkpatrick E, Qiu X, Wilson PC, Bahl J, Krammer F.

Sci Rep. 2018 Jul 11;8(1):10432. doi: 10.1038/s41598-018-28706-1.

45.

Direct Visualization of the Conformational Dynamics of Single Influenza Hemagglutinin Trimers.

Das DK, Govindan R, Nikić-Spiegel I, Krammer F, Lemke EA, Munro JB.

Cell. 2018 Aug 9;174(4):926-937.e12. doi: 10.1016/j.cell.2018.05.050. Epub 2018 Jun 28.

46.

Influenza.

Krammer F, Smith GJD, Fouchier RAM, Peiris M, Kedzierska K, Doherty PC, Palese P, Shaw ML, Treanor J, Webster RG, García-Sastre A.

Nat Rev Dis Primers. 2018 Jun 28;4(1):3. doi: 10.1038/s41572-018-0002-y. Review. No abstract available.

PMID:
29955068
47.

Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model.

Stadlbauer D, Amanat F, Strohmeier S, Nachbagauer R, Krammer F.

Emerg Microbes Infect. 2018 Jun 20;7(1):110. doi: 10.1038/s41426-018-0115-0.

48.

Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge.

Nachbagauer R, Shore D, Yang H, Johnson SK, Gabbard JD, Tompkins SM, Wrammert J, Wilson PC, Stevens J, Ahmed R, Krammer F, Ellebedy AH.

J Virol. 2018 Jul 31;92(16). pii: e00949-18. doi: 10.1128/JVI.00949-18. Print 2018 Aug 15.

49.

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

Pardi N, Hogan MJ, Naradikian MS, Parkhouse K, Cain DW, Jones L, Moody MA, Verkerke HP, Myles A, Willis E, LaBranche CC, Montefiori DC, Lobby JL, Saunders KO, Liao HX, Korber BT, Sutherland LL, Scearce RM, Hraber PT, Tombácz I, Muramatsu H, Ni H, Balikov DA, Li C, Mui BL, Tam YK, Krammer F, Karikó K, Polacino P, Eisenlohr LC, Madden TD, Hope MJ, Lewis MG, Lee KK, Hu SL, Hensley SE, Cancro MP, Haynes BF, Weissman D.

J Exp Med. 2018 Jun 4;215(6):1571-1588. doi: 10.1084/jem.20171450. Epub 2018 May 8.

50.

Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses.

Amanat F, Duehr J, Oestereich L, Hastie KM, Ollmann Saphire E, Krammer F.

mSphere. 2018 May 2;3(3). pii: e00189-18. doi: 10.1128/mSphere.00189-18. eCollection 2018 May-Jun.

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