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Splenic injury severity, not admission hemodynamics, predicts need for surgery in pediatric blunt splenic trauma.

Teuben M, Spijkerman R, Teuber H, Pfeifer R, Pape HC, Kramer W, Leenen L.

Patient Saf Surg. 2020 Jan 3;14:1. doi: 10.1186/s13037-019-0218-0. eCollection 2020. No abstract available.


Small-scale preparation of perfluorocarbon-nanoemulsions utilizing dual centrifugation.

Krämer W, Schubert R, Massing U.

Int J Pharm. 2019 Dec 15;572:118753. doi: 10.1016/j.ijpharm.2019.118753. Epub 2019 Oct 31.


Ultrasound markers predicting complex gastroschisis and adverse outcome: a longitudinal prospective nationwide cohort study.

Lap CCMM, Pistorius LR, Mulder EJH, Aliasi M, Kramer WLM, Bilardo CM, Cohen-Overbeek TE, Pajkrt E, Tibboel D, Wijnen RMH, Visser GHA, Manten GTR; FLAMINGO-study -workinggroup.

Ultrasound Obstet Gynecol. 2019 Oct 15. doi: 10.1002/uog.21888. [Epub ahead of print]


Using three-dimensional ultrasound in predicting complex gastroschisis: A longitudinal, prospective, multicenter cohort study.

Hijkoop A, Lap CCMM, Aliasi M, Mulder EJH, Kramer WLM, Brouwers HAA, van Baren R, Pajkrt E, van Kaam AH, Bilardo CM, Pistorius LR, Visser GHA, Wijnen RMH, Tibboel D, Manten GTR, Cohen-Overbeek TE.

Prenat Diagn. 2019 Dec;39(13):1204-1212. doi: 10.1002/pd.5568. Epub 2019 Oct 25.


Evaluation of a novel screening method for fetal aneuploidy using cell-free DNA in maternal plasma.

Porreco RP, Sekedat M, Bombard A, Garite TJ, Maurel K, Marusiak B, Adair D, Bleich A, Combs CA, Kramer W, Longo S, Nageotte M, Samuel A, Vanderhoeven J, Buis J, Jacobs KB, Stoerker J.

J Med Screen. 2019 Sep 11:969141319873682. doi: 10.1177/0969141319873682. [Epub ahead of print] No abstract available.


Ocular Distribution of Cyclosporine Following Topical Administration of OTX-101 in New Zealand White Rabbits.

Weiss SL, Kramer WG.

J Ocul Pharmacol Ther. 2019 Sep;35(7):395-402. doi: 10.1089/jop.2018.0106. Epub 2019 Aug 6.


Rational manufacturing of functionalized, long-term stable perfluorocarbon-nanoemulsions for site-specific 19F magnetic resonance imaging.

Krämer W, Grapentin C, Bouvain P, Temme S, Flögel U, Schubert R.

Eur J Pharm Biopharm. 2019 Sep;142:114-122. doi: 10.1016/j.ejpb.2019.06.014. Epub 2019 Jun 18.


Fostering improved human islet research: a European perspective.

Marchetti P, Schulte AM, Marselli L, Schoniger E, Bugliani M, Kramer W, Overbergh L, Ullrich S, Gloyn AL, Ibberson M, Rutter G, Froguel P, Groop L, McCarthy MI, Dotta F, Scharfmann R, Magnan C, Eizirik DL, Mathieu C, Cnop M, Thorens B, Solimena M.

Diabetologia. 2019 Aug;62(8):1514-1516. doi: 10.1007/s00125-019-4911-4. Epub 2019 Jun 13. No abstract available.


A phase 1, open-label, single-arm study evaluating the ocular safety of OTX-101 and systemic absorption of cyclosporine in healthy human volunteers.

Karpecki PM, Weiss SL, Kramer WG, O'Connor P, Evans D, Johnston J, Jasper AL, Justice A, Ogundele AB, Devries D.

Clin Ophthalmol. 2019 Apr 5;13:591-596. doi: 10.2147/OPTH.S187945. eCollection 2019.


Nonglucuronidated Ezetimibe Disrupts CD13- and CD64-Coassembly in Membrane Microdomains and Decreases Cellular Cholesterol Content in Human Monocytes/Macrophages.

Orsó E, Robenek H, Boettcher A, Wolf Z, Liebisch G, Kramer W, Schmitz G.

Cytometry A. 2019 Aug;95(8):869-884. doi: 10.1002/cyto.a.23772. Epub 2019 Apr 17.


Structure, Spectroscopy, and Electrochemistry of Manganese(I) and Rhenium(I) Quinoline Oximes.

Ngo DX, Kramer WW, McNicholas BJ, Gray HB, Brennan BJ.

Inorg Chem. 2019 Jan 7;58(1):737-746. doi: 10.1021/acs.inorgchem.8b02862. Epub 2018 Dec 21.


Primary signet-ring stromal tumour of the testis: case report with literature review.

Fichtner A, Fisseler-Eckhoff A, Kramer W, Radzun HJ, Ströbel P, Bremmer F.

APMIS. 2019 Jan;127(1):45-49. doi: 10.1111/apm.12907.


Insulin translates unfavourable lifestyle into obesity.

Kolb H, Stumvoll M, Kramer W, Kempf K, Martin S.

BMC Med. 2018 Dec 13;16(1):232. doi: 10.1186/s12916-018-1225-1. Review.


Dissociation of 19F and fluorescence signal upon cellular uptake of dual-contrast perfluorocarbon nanoemulsions.

Bouvain P, Flocke V, Krämer W, Schubert R, Schrader J, Flögel U, Temme S.

MAGMA. 2019 Feb;32(1):133-145. doi: 10.1007/s10334-018-0723-7. Epub 2018 Nov 29.


Synthetic Cargo Internalization Receptor System for Nanoparticle Tracking of Individual Cell Populations by Fluorine Magnetic Resonance Imaging.

Temme S, Baran P, Bouvain P, Grapentin C, Krämer W, Knebel B, Al-Hasani H, Moll JM, Floss D, Schrader J, Schubert R, Flögel U, Scheller J.

ACS Nano. 2018 Nov 27;12(11):11178-11192. doi: 10.1021/acsnano.8b05698. Epub 2018 Nov 5.


Effects of Doxorubicin on the Liquid-Liquid Phase Change Properties of Elastin-Like Polypeptides.

Zai-Rose V, West SJ, Kramer WH, Bishop GR, Lewis EA, Correia JJ.

Biophys J. 2018 Oct 16;115(8):1431-1444. doi: 10.1016/j.bpj.2018.09.006. Epub 2018 Sep 15.


A cohort study to evaluate infection prevention protocol in pediatric trauma patients with blunt splenic injury in a Dutch level 1 trauma center.

Spijkerman R, Teuben MP, Hietbrink F, Kramer WL, Leenen LP.

Patient Prefer Adherence. 2018 Aug 28;12:1607-1617. doi: 10.2147/PPA.S169072. eCollection 2018.


Orthopedic Injuries in Professional Surfers: A Retrospective Study at a Single Orthopedic Center.

Hohn E, Robinson S, Merriman J, Parrish R, Kramer W.

Clin J Sport Med. 2018 Mar 23. doi: 10.1097/JSM.0000000000000596. [Epub ahead of print]


Phase 1 trial of vamorolone, a first-in-class steroid, shows improvements in side effects via biomarkers bridged to clinical outcomes.

Hoffman EP, Riddle V, Siegler MA, Dickerson D, Backonja M, Kramer WG, Nagaraju K, Gordish-Dressman H, Damsker JM, McCall JM.

Steroids. 2018 Jun;134:43-52. doi: 10.1016/j.steroids.2018.02.010. Epub 2018 Mar 8.


Pharmacokinetics of Diclofenac and Hydroxypropyl-β-Cyclodextrin (HPβCD) Following Administration of Injectable HPβCD-Diclofenac in Subjects With Mild to Moderate Renal Insufficiency or Mild Hepatic Impairment.

Hamilton DA, Ernst CC, Kramer WG, Madden D, Lang E, Liao E, Lacouture PG, Ramaiya A, Carr DB.

Clin Pharmacol Drug Dev. 2018 Feb;7(2):110-122. doi: 10.1002/cpdd.417. Epub 2017 Dec 2.


Triphenylsulfonium topophotochemistry.

Despagnet-Ayoub E, Kramer WW, Sattler W, Sattler A, LaBeaume PJ, Thackeray JW, Cameron JF, Cardolaccia T, Rachford AA, Winkler JR, Gray HB.

Photochem Photobiol Sci. 2018 Jan 17;17(1):27-34. doi: 10.1039/c7pp00324b.


Pharmacokinetics, Pharmacodynamics, and Safety of a Long-Acting Human Growth Hormone (MOD-4023) in Healthy Japanese and Caucasian Adults.

Kramer WG, Jaron-Mendelson M, Koren R, Hershkovitz O, Hart G.

Clin Pharmacol Drug Dev. 2018 Jun;7(5):554-563. doi: 10.1002/cpdd.414. Epub 2017 Nov 14.


Saccharomyces cerevisiae Gle2/Rae1 is involved in septin organization, essential for cell cycle progression.

Zander G, Kramer W, Seel A, Krebber H.

Yeast. 2017 Nov;34(11):459-470. doi: 10.1002/yea.3249. Epub 2017 Sep 28.


Seasonal variation modulates coral sensibility to heat-stress and explains annual changes in coral productivity.

Scheufen T, Krämer WE, Iglesias-Prieto R, Enríquez S.

Sci Rep. 2017 Jul 10;7(1):4937. doi: 10.1038/s41598-017-04927-8.


Disclosure and donor-conceived children.

Crawshaw M, Adams D, Allan S, Blyth E, Bourne K, Brügge C, Chien A, Clissa A, Daniels K, Glazer E, Haase J, Hammarberg K, van Hooff H, Hunt J, Indekeu A, Johnson L, Kim Y, Kirkman M, Kramer W, Lalos A, Lister C, Lowinger P, Mindes E, Monach J, Montuschi O, Pike S, Powell V, Rodino I, Ruby A, Margriet Schrijvers A, Semba Y, Shidlo R, Thorn P, Tonkin L, Visser M, Woodward J, Wischmann T, Yee S, Zweifel JE.

Hum Reprod. 2017 Jul 1;32(7):1535-1536. doi: 10.1093/humrep/dex107. No abstract available.


Absorptance determinations on multicellular tissues.

Vásquez-Elizondo RM, Legaria-Moreno L, Pérez-Castro MÁ, Krämer WE, Scheufen T, Iglesias-Prieto R, Enríquez S.

Photosynth Res. 2017 Jun;132(3):311-324. doi: 10.1007/s11120-017-0395-6. Epub 2017 May 10.


Long-term breast cancer risk following ovarian stimulation in young egg donors: a call for follow-up, research and informed consent.

Schneider J, Lahl J, Kramer W.

Reprod Biomed Online. 2017 May;34(5):480-485. doi: 10.1016/j.rbmo.2017.02.003.


Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.

Wigger L, Cruciani-Guglielmacci C, Nicolas A, Denom J, Fernandez N, Fumeron F, Marques-Vidal P, Ktorza A, Kramer W, Schulte A, Le Stunff H, Liechti R, Xenarios I, Vollenweider P, Waeber G, Uphues I, Roussel R, Magnan C, Ibberson M, Thorens B.

Cell Rep. 2017 Feb 28;18(9):2269-2279. doi: 10.1016/j.celrep.2017.02.019.


Adolescents Conceived through Donor Insemination in Mother-Headed Families: A Qualitative Study of Motivations and Experiences of Contacting and Meeting Same-donor Offspring.

Persaud S, Freeman T, Jadva V, Slutsky J, Kramer W, Steele M, Steele H, Golombok S.

Child Soc. 2017 Jan;31(1):13-22. doi: 10.1111/chso.12158. Epub 2016 Apr 14.


A Phase I study evaluating the effect of age and weight on the pharmacokinetics of an injectable formulation of diclofenac solubilized with hydroxypropyl-β-cyclodextrin.

Goldwater R, Kramer WG, Hamilton DA, Lang E, Wang J, Madden DE, Lacouture PG, Ramaiya A, Carr DB.

Clin Pharmacol. 2016 Dec 15;8:203-212. doi: 10.2147/CPAA.S98437. eCollection 2016.


Outcome of isolated gastroschisis; an international study, systematic review and meta-analysis.

Lap CC, Brizot ML, Pistorius LR, Kramer WL, Teeuwen IB, Eijkemans MJ, Brouwers HA, Pajkrt E, van Kaam AH, van Scheltema PN, Eggink AJ, van Heijst AF, Haak MC, van Weissenbruch MM, Sleeboom C, Willekes C, van der Hoeven MA, van Heurn EL, Bilardo CM, Dijk PH, van Baren R, Francisco RP, Tannuri AC, Visser GH, Manten GT.

Early Hum Dev. 2016 Dec;103:209-218. doi: 10.1016/j.earlhumdev.2016.10.002. Epub 2016 Oct 27.


Bioavailability study of dronabinol oral solution versus dronabinol capsules in healthy volunteers.

Parikh N, Kramer WG, Khurana V, Cognata Smith C, Vetticaden S.

Clin Pharmacol. 2016 Oct 12;8:155-162. eCollection 2016.


Gamete donor anonymity and limits on numbers of offspring: the views of three stakeholders.

Nelson MK, Hertz R, Kramer W.

J Law Biosci. 2015 Oct 29;3(1):39-67. eCollection 2016 Apr.


Electrocatalysis of CO2 Reduction in Brush Polymer Ion Gels.

McNicholas BJ, Blakemore JD, Chang AB, Bates CM, Kramer WW, Grubbs RH, Gray HB.

J Am Chem Soc. 2016 Sep 7;138(35):11160-3. doi: 10.1021/jacs.6b08795. Epub 2016 Aug 29.


[Management of blunt renal trauma in paediatric patients].

Brouwers L, Bemelman M, Kramer WL, van der Heijden FH.

Ned Tijdschr Geneeskd. 2016;160:D284. Dutch.


Polymer coordination promotes selective CO2 reduction by cobalt phthalocyanine.

Kramer WW, McCrory CCL.

Chem Sci. 2016 Apr 21;7(4):2506-2515. doi: 10.1039/c5sc04015a. Epub 2016 Feb 2.


Identification of novel inhibitors of the steroid sulfate carrier 'sodium-dependent organic anion transporter' SOAT (SLC10A6) by pharmacophore modelling.

Grosser G, Baringhaus KH, Döring B, Kramer W, Petzinger E, Geyer J.

Mol Cell Endocrinol. 2016 Jun 15;428:133-41. doi: 10.1016/j.mce.2016.03.028. Epub 2016 Mar 23.


Integrating donor conception into identity development: adolescents in fatherless families.

Slutsky J, Jadva V, Freeman T, Persaud S, Steele M, Steele H, Kramer W, Golombok S.

Fertil Steril. 2016 Jul;106(1):202-208. doi: 10.1016/j.fertnstert.2016.02.033. Epub 2016 Mar 21.


Management of a Giant Omphalocele with Non-Cross-Linked Intact Porcine-Derived Acellular Dermal Matrix (Strattice) Combined with Vacuum Therapy.

Travassos DV, van Eerde AM, Kramer WL.

European J Pediatr Surg Rep. 2015 Dec;3(2):61-3. doi: 10.1055/s-0035-1549364. Epub 2015 Jun 26.


Optimization of the Coupled Cluster Implementation in NWChem on Petascale Parallel Architectures.

Anisimov VM, Bauer GH, Chadalavada K, Olson RM, Glenski JW, Kramer WT, Aprà E, Kowalski K.

J Chem Theory Comput. 2014 Oct 14;10(10):4307-16. doi: 10.1021/ct500404c.


Emerging models for facilitating contact between people genetically related through donor conception: a preliminary analysis and discussion.

Crawshaw M, Daniels K, Adams D, Bourne K, van Hooff JAP, Kramer W, Pasch L, Thorn P.

Reprod Biomed Soc Online. 2015 Nov 10;1(2):71-80. doi: 10.1016/j.rbms.2015.10.001. eCollection 2015 Dec.


Gendering gametes: The unequal contributions of sperm and egg donors.

Hertz R, Nelson MK, Kramer W.

Soc Sci Med. 2015 Dec;147:10-9. doi: 10.1016/j.socscimed.2015.10.049. Epub 2015 Oct 21.


Evaluation of a Scenario in Which Estimates of Bioequivalence Are Biased and a Proposed Solution: tlast (Common).

Fisher D, Kramer W, Burmeister Getz E.

J Clin Pharmacol. 2016 Jul;56(7):794-800. doi: 10.1002/jcph.663. Epub 2015 Dec 28.


A Robust and Versatile Method of Combinatorial Chemical Synthesis of Gene Libraries via Hierarchical Assembly of Partially Randomized Modules.

Popova B, Schubert S, Bulla I, Buchwald D, Kramer W.

PLoS One. 2015 Sep 10;10(9):e0136778. doi: 10.1371/journal.pone.0136778. eCollection 2015.


Antilipidemic Drug Therapy Today and in the Future.

Kramer W.

Handb Exp Pharmacol. 2016;233:373-435. doi: 10.1007/164_2015_15. Review.


Pancreatic β-cell imaging in humans: fiction or option?

Laurent D, Vinet L, Lamprianou S, Daval M, Filhoulaud G, Ktorza A, Wang H, Sewing S, Juretschke HP, Glombik H, Meda P, Boisgard R, Nguyen DL, Stasiuk GJ, Long NJ, Montet X, Hecht P, Kramer W, Rutter GA, Hecksher-Sørensen J.

Diabetes Obes Metab. 2016 Jan;18(1):6-15. doi: 10.1111/dom.12544. Epub 2015 Oct 5. Review.


Sperm donors describe the experience of contact with their donor-conceived offspring.

Hertz R, Nelson MK, Kramer W.

Facts Views Vis Obgyn. 2015;7(2):91-100.


[Malrotation with or without volvulus].

Heidsma CM, Hulsker CC, van der Zee D, Kramer WH.

Ned Tijdschr Geneeskd. 2015;159:A8859. Review. Dutch.


Clinical Prediction Models for Cardiovascular Disease: Tufts Predictive Analytics and Comparative Effectiveness Clinical Prediction Model Database.

Wessler BS, Lai Yh L, Kramer W, Cangelosi M, Raman G, Lutz JS, Kent DM.

Circ Cardiovasc Qual Outcomes. 2015 Jul;8(4):368-75. doi: 10.1161/CIRCOUTCOMES.115.001693. Epub 2015 Jul 7. Review.

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