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Items: 1 to 50 of 333

1.

Aerosolization Performance of Jet Nebulizers and Biopharmaceutical Aspects.

Adorni G, Seifert G, Buttini F, Colombo G, Stecanella LA, Krämer I, Rossi A.

Pharmaceutics. 2019 Aug 11;11(8). pii: E406. doi: 10.3390/pharmaceutics11080406.

2.

Basal and Postprandial Myofibrillar Protein Synthesis Rates Do Not Differ between Lean and Obese Middle-Aged Men.

Kouw IWK, van Dijk JW, Horstman AMH, Kramer IF, Goessens JPB, van Dielen FMH, Verdijk LB, van Loon LJC.

J Nutr. 2019 Sep 1;149(9):1533-1542. doi: 10.1093/jn/nxz104.

3.

Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men.

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig WKWH, Verdijk LB, de Groot LCPGM, van Loon LJC.

Am J Physiol Endocrinol Metab. 2019 Sep 1;317(3):E473-E482. doi: 10.1152/ajpendo.00073.2019. Epub 2019 May 21.

PMID:
31112406
4.

Systemic sclerostin antibody treatment increases osseointegration and biomechanical competence of zoledronic-acid-coated dental implants in a rat osteoporosis model.

Korn P, Kramer I, Schlottig F, Tödtman N, Eckelt U, Bürki A, Ferguson SJ, Kautz A, Schnabelrauch M, Range U, Kneissel M, Stadlinger B.

Eur Cell Mater. 2019 May 17;37:333-346. doi: 10.22203/eCM.v037a20.

5.

Dose-Dependent Increases in Whole-Body Net Protein Balance and Dietary Protein-Derived Amino Acid Incorporation into Myofibrillar Protein During Recovery from Resistance Exercise in Older Men.

Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig WKWH, Verdijk LB, van Loon LJC.

J Nutr. 2019 Feb 1;149(2):221-230. doi: 10.1093/jn/nxy263.

6.

The influence of adjuvant systemic regimens on contralateral breast cancer risk and receptor subtype.

Kramer I, Schaapveld M, Oldenburg HSA, Sonke GS, McCool D, van Leeuwen FE, Van de Vijver KK, Russell NS, Linn SC, Siesling S, Menke-van der Houven van Oordt CW, Schmidt MK.

J Natl Cancer Inst. 2019 Jan 30. doi: 10.1093/jnci/djz010. [Epub ahead of print]

PMID:
30698719
7.

CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE.

Wlodarczyk A, Benmamar-Badel A, Cédile O, Jensen KN, Kramer I, Elsborg NB, Owens T.

Front Cell Neurosci. 2019 Jan 10;12:523. doi: 10.3389/fncel.2018.00523. eCollection 2018.

8.

Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients.

Kramer IF, Blokhuis TJ, Verdijk LB, van Loon LJC, Poeze M.

Nutr Rev. 2019 Apr 1;77(4):254-266. doi: 10.1093/nutrit/nuy055.

PMID:
30624706
9.

[Variations on the theme of podosomes, context matters].

Alonso F, Spuul P, Kramer I, Génot E.

Med Sci (Paris). 2018 Dec;34(12):1063-1070. doi: 10.1051/medsci/2018296. Epub 2019 Jan 9. Review. French.

PMID:
30623771
10.

Variations on the theme of podosomes: A matter of context.

Alonso F, Spuul P, Daubon T, Kramer I, Génot E.

Biochim Biophys Acta Mol Cell Res. 2019 Apr;1866(4):545-553. doi: 10.1016/j.bbamcr.2018.12.009. Epub 2018 Dec 27. Review.

PMID:
30594495
11.

[Drug Output and Aerosol Characteristics of Different Jet Nebulisers for Adults While Simulating the Nebulisation of Salbutamol].

Walz-Jung H, Krämer I, Kamin W.

Pneumologie. 2018 Dec;72(12):820-831. doi: 10.1055/a-0749-5520. Epub 2018 Nov 19. German.

PMID:
30453377
12.

Interleukin-17A Inhibition Diminishes Inflammation and New Bone Formation in Experimental Spondyloarthritis.

van Tok MN, van Duivenvoorde LM, Kramer I, Ingold P, Pfister S, Roth L, Blijdorp IC, van de Sande MGH, Taurog JD, Kolbinger F, Baeten DL.

Arthritis Rheumatol. 2019 Apr;71(4):612-625. doi: 10.1002/art.40770. Epub 2019 Feb 18.

PMID:
30390386
13.

Virulence-associated protein A from Rhodococcus equi is an intercompartmental pH-neutralising virulence factor.

von Bargen K, Scraba M, Krämer I, Ketterer M, Nehls C, Krokowski S, Repnik U, Wittlich M, Maaser A, Zapka P, Bunge M, Schlesinger M, Huth G, Klees A, Hansen P, Jeschke A, Bendas G, Utermöhlen O, Griffiths G, Gutsmann T, Wohlmann J, Haas A.

Cell Microbiol. 2019 Jan;21(1):e12958. doi: 10.1111/cmi.12958. Epub 2018 Nov 9.

PMID:
30251327
14.

Efficacy of four cleaning solutions for the decontamination of selected cytotoxic drugs on the different surfaces of an automated compounding system.

Federici M, Raffaelli J, Paolucci D, Schierl R, Krämer I.

J Occup Environ Hyg. 2019 Jan;16(1):6-15. doi: 10.1080/15459624.2018.1526384. Epub 2019 Jan 18.

PMID:
30230976
15.

One Week of Hospitalization Following Elective Hip Surgery Induces Substantial Muscle Atrophy in Older Patients.

Kouw IWK, Groen BBL, Smeets JSJ, Kramer IF, van Kranenburg JMX, Nilwik R, Geurts JAP, Ten Broeke RHM, Poeze M, van Loon LJC, Verdijk LB.

J Am Med Dir Assoc. 2019 Jan;20(1):35-42. doi: 10.1016/j.jamda.2018.06.018. Epub 2018 Aug 11.

PMID:
30108034
16.

Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume.

Morse A, Cheng TL, Schindeler A, McDonald MM, Mohanty ST, Kneissel M, Kramer I, Little DG.

Calcif Tissue Int. 2018 Sep;103(3):298-310. doi: 10.1007/s00223-018-0420-6. Epub 2018 May 29.

PMID:
29845410
17.

Sost deficiency leads to reduced mechanical strains at the tibia midshaft in strain-matched in vivo loading experiments in mice.

Albiol L, Cilla M, Pflanz D, Kramer I, Kneissel M, Duda GN, Willie BM, Checa S.

J R Soc Interface. 2018 Apr;15(141). pii: 20180012. doi: 10.1098/rsif.2018.0012.

18.

Developmentally inspired programming of adult human mesenchymal stromal cells toward stable chondrogenesis.

Occhetta P, Pigeot S, Rasponi M, Dasen B, Mehrkens A, Ullrich T, Kramer I, Guth-Gundel S, Barbero A, Martin I.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4625-4630. doi: 10.1073/pnas.1720658115. Epub 2018 Apr 16.

19.

Economic evaluation of an experience sampling method intervention in depression compared with treatment as usual using data from a randomized controlled trial.

Simons CJP, Drukker M, Evers S, van Mastrigt GAPG, Höhn P, Kramer I, Peeters F, Delespaul P, Menne-Lothmann C, Hartmann JA, van Os J, Wichers M.

BMC Psychiatry. 2017 Dec 29;17(1):415. doi: 10.1186/s12888-017-1577-7.

20.

Sclerostin deficiency modifies the development of CKD-MBD in mice.

Kaesler N, Verhulst A, De Maré A, Deck A, Behets GJ, Hyusein A, Evenepoel P, Floege J, Marx N, Babler A, Kramer I, Kneissel M, Kramann R, Weis D, D'Haese PC, Brandenburg VM.

Bone. 2018 Feb;107:115-123. doi: 10.1016/j.bone.2017.11.015. Epub 2017 Nov 21.

PMID:
29175269
21.

Handling the phosphorus paradox in agriculture and natural ecosystems: Scarcity, necessity, and burden of P.

Leinweber P, Bathmann U, Buczko U, Douhaire C, Eichler-Löbermann B, Frossard E, Ekardt F, Jarvie H, Krämer I, Kabbe C, Lennartz B, Mellander PE, Nausch G, Ohtake H, Tränckner J.

Ambio. 2018 Jan;47(Suppl 1):3-19. doi: 10.1007/s13280-017-0968-9. Review.

22.

Sclerostin Antibody Augments the Anabolic Bone Formation Response in a Mouse Model of Mechanical Tibial Loading.

Morse A, Schindeler A, McDonald MM, Kneissel M, Kramer I, Little DG.

J Bone Miner Res. 2018 Mar;33(3):486-498. doi: 10.1002/jbmr.3330. Epub 2017 Nov 29.

23.

Physicochemical stability of carfilzomib (Kyprolis®) containing solutions in glass vials, ready-to-administer plastic syringes and infusion bags over a 28-day storage period.

Kim SH, Krämer I.

J Oncol Pharm Pract. 2017 Jan 1:1078155217735881. doi: 10.1177/1078155217735881. [Epub ahead of print]

PMID:
29059027
24.

Loading-Induced Reduction in Sclerostin as a Mechanism of Subchondral Bone Plate Sclerosis in Mouse Knee Joints During Late-Stage Osteoarthritis.

Jia H, Ma X, Wei Y, Tong W, Tower RJ, Chandra A, Wang L, Sun Z, Yang Z, Badar F, Zhang K, Tseng WJ, Kramer I, Kneissel M, Xia Y, Liu XS, Wang JHC, Han L, Enomoto-Iwamoto M, Qin L.

Arthritis Rheumatol. 2018 Feb;70(2):230-241. doi: 10.1002/art.40351. Epub 2017 Dec 29.

25.

A novel microglial subset plays a key role in myelinogenesis in developing brain.

Wlodarczyk A, Holtman IR, Krueger M, Yogev N, Bruttger J, Khorooshi R, Benmamar-Badel A, de Boer-Bergsma JJ, Martin NA, Karram K, Kramer I, Boddeke EW, Waisman A, Eggen BJ, Owens T.

EMBO J. 2017 Nov 15;36(22):3292-3308. doi: 10.15252/embj.201696056. Epub 2017 Sep 28.

26.

Neural stem cells induce the formation of their physical niche during organogenesis.

Seleit A, Krämer I, Riebesehl BF, Ambrosio EM, Stolper JS, Lischik CQ, Dross N, Centanin L.

Elife. 2017 Sep 27;6. pii: e29173. doi: 10.7554/eLife.29173.

27.

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial.

Kouw IW, Holwerda AM, Trommelen J, Kramer IF, Bastiaanse J, Halson SL, Wodzig WK, Verdijk LB, van Loon LJ.

J Nutr. 2017 Dec;147(12):2252-2261. doi: 10.3945/jn.117.254532. Epub 2017 Aug 30.

PMID:
28855419
28.

Sost deficiency led to a greater cortical bone formation response to mechanical loading and altered gene expression.

Pflanz D, Birkhold AI, Albiol L, Thiele T, Julien C, Seliger A, Thomson E, Kramer I, Kneissel M, Duda GN, Kornak U, Checa S, Willie BM.

Sci Rep. 2017 Aug 25;7(1):9435. doi: 10.1038/s41598-017-09653-9.

29.

Allogeneic hematopoietic cell transplantation for high-risk CLL: 10-year follow-up of the GCLLSG CLL3X trial.

Krämer I, Stilgenbauer S, Dietrich S, Böttcher S, Zeis M, Stadler M, Bittenbring J, Uharek L, Scheid C, Hegenbart U, Ho A, Hallek M, Kneba M, Schmitz N, Döhner H, Dreger P.

Blood. 2017 Sep 21;130(12):1477-1480. doi: 10.1182/blood-2017-04-775841. Epub 2017 Jul 17. No abstract available.

PMID:
28716861
30.

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma.

McDonald MM, Reagan MR, Youlten SE, Mohanty ST, Seckinger A, Terry RL, Pettitt JA, Simic MK, Cheng TL, Morse A, Le LMT, Abi-Hanna D, Kramer I, Falank C, Fairfield H, Ghobrial IM, Baldock PA, Little DG, Kneissel M, Vanderkerken K, Bassett JHD, Williams GR, Oyajobi BO, Hose D, Phan TG, Croucher PI.

Blood. 2017 Jun 29;129(26):3452-3464. doi: 10.1182/blood-2017-03-773341. Epub 2017 May 17.

31.

Combination sclerostin antibody and zoledronic acid treatment outperforms either treatment alone in a mouse model of osteogenesis imperfecta.

Little DG, Peacock L, Mikulec K, Kneissel M, Kramer I, Cheng TL, Schindeler A, Munns C.

Bone. 2017 Aug;101:96-103. doi: 10.1016/j.bone.2017.04.016. Epub 2017 Apr 29.

PMID:
28461254
32.

The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis.

Fairfield H, Falank C, Harris E, Demambro V, McDonald M, Pettitt JA, Mohanty ST, Croucher P, Kramer I, Kneissel M, Rosen CJ, Reagan MR.

J Cell Physiol. 2018 Feb;233(2):1156-1167. doi: 10.1002/jcp.25976. Epub 2017 Jun 6.

33.

Extensive Type II Muscle Fiber Atrophy in Elderly Female Hip Fracture Patients.

Kramer IF, Snijders T, Smeets JSJ, Leenders M, van Kranenburg J, den Hoed M, Verdijk LB, Poeze M, van Loon LJC.

J Gerontol A Biol Sci Med Sci. 2017 Oct 1;72(10):1369-1375. doi: 10.1093/gerona/glw253.

PMID:
28329045
34.

Analysis of prognostic factors in patients with newly diagnosed diffuse large B-cell lymphoma and skeletal involvement.

Lehners N, Krämer I, Saadati M, Benner A, Ho AD, Witzens-Harig M.

BMC Cancer. 2017 Feb 13;17(1):128. doi: 10.1186/s12885-017-3113-z.

35.

Molecular and clinical analysis of ALPL in a cohort of patients with suspicion of Hypophosphatasia.

Tenorio J, Álvarez I, Riancho-Zarrabeitia L, Martos-Moreno GÁ, Mandrile G, de la Flor Crespo M, Sukchev M, Sherif M, Kramer I, Darnaude-Ortiz MT, Arias P, Gordo G, Dapía I, Martinez-Villanueva J, Gómez R, Iturzaeta JM, Otaify G, García-Unzueta M, Rubinacci A, Riancho JA, Aglan M, Temtamy S, Hamid MA, Argente J, Ruiz-Pérez VL, Heath KE, Lapunzina P.

Am J Med Genet A. 2017 Mar;173(3):601-610. doi: 10.1002/ajmg.a.37991. Epub 2017 Jan 27.

PMID:
28127875
36.

Sequential organogenesis sets two parallel sensory lines in medaka.

Seleit A, Krämer I, Ambrosio E, Dross N, Engel U, Centanin L.

Development. 2017 Feb 15;144(4):687-697. doi: 10.1242/dev.142752. Epub 2017 Jan 13.

37.

Non-invasive imaging demonstrates clinical features of ankylosing spondylitis in a rat adjuvant model: a case study.

Accart N, Dawson J, Kolbinger F, Kramer I, Beckmann N.

Eur J Histochem. 2016 Nov 2;60(4):2667. doi: 10.4081/ejh.2016.2667.

38.

Robotic i.v. medication compounding: Recommendations from the international community of APOTECAchemo users.

Yaniv AW, Orsborn A, Bonkowski JJ, Chew L, Krämer I, Calabrese S, de la Paz Pacheco Ramos M, Palombi A, Lim SW, Tabbara O, Masini C, Schierl R, Bufarini C, Peaty N, Paolucci D.

Am J Health Syst Pharm. 2017 Jan 1;74(1):e40-e46. doi: 10.2146/ajhp151027. Epub 2016 Dec 22.

PMID:
28007720
39.

Compatibility of epirubicin-loaded DC bead™ with different non-ionic contrast media.

Sarakbi I, Krämer I.

J Oncol Pharm Pract. 2016 Dec;22(6):749-756. Epub 2015 Oct 1.

PMID:
26428284
40.

Suppression of Sclerostin Alleviates Radiation-Induced Bone Loss by Protecting Bone-Forming Cells and Their Progenitors Through Distinct Mechanisms.

Chandra A, Lin T, Young T, Tong W, Ma X, Tseng WJ, Kramer I, Kneissel M, Levine MA, Zhang Y, Cengel K, Liu XS, Qin L.

J Bone Miner Res. 2017 Feb;32(2):360-372. doi: 10.1002/jbmr.2996. Epub 2016 Oct 20.

41.

[Practical aspects in the use of biosimilar insulins].

Krämer I, Blüher M, Kuhlmann MK, Heinemann L.

Dtsch Med Wochenschr. 2016 Oct;141(21):1565-1568. Epub 2016 Oct 17. Review. German.

PMID:
27750344
42.

Both basal and post-prandial muscle protein synthesis rates, following the ingestion of a leucine-enriched whey protein supplement, are not impaired in sarcopenic older males.

Kramer IF, Verdijk LB, Hamer HM, Verlaan S, Luiking YC, Kouw IWK, Senden JM, van Kranenburg J, Gijsen AP, Bierau J, Poeze M, van Loon LJC.

Clin Nutr. 2017 Oct;36(5):1440-1449. doi: 10.1016/j.clnu.2016.09.023. Epub 2016 Sep 29.

PMID:
27743615
43.

VEGF-A/Notch-Induced Podosomes Proteolyse Basement Membrane Collagen-IV during Retinal Sprouting Angiogenesis.

Spuul P, Daubon T, Pitter B, Alonso F, Fremaux I, Kramer I, Montanez E, Génot E.

Cell Rep. 2016 Oct 4;17(2):484-500. doi: 10.1016/j.celrep.2016.09.016.

44.

Only minor differences in renal osteodystrophy features between wild-type and sclerostin knockout mice with chronic kidney disease.

Cejka D, Parada-Rodriguez D, Pichler S, Marculescu R, Kramer I, Kneissel M, Gross T, Reisinger A, Pahr D, Monier-Faugere MC, Haas M, Malluche HH.

Kidney Int. 2016 Oct;90(4):828-34. doi: 10.1016/j.kint.2016.06.019. Epub 2016 Aug 12.

45.

Lenalidomide enhances myeloma-specific T-cell responses in vivo and in vitro.

Krämer I, Engelhardt M, Fichtner S, Neuber B, Medenhoff S, Bertsch U, Hillengass J, Raab MS, Hose D, Ho AD, Goldschmidt H, Hundemer M.

Oncoimmunology. 2016 Feb 18;5(5):e1139662. doi: 10.1080/2162402X.2016.1139662. eCollection 2016 May.

46.

S100A6 Regulates Endothelial Cell Cycle Progression by Attenuating Antiproliferative Signal Transducers and Activators of Transcription 1 Signaling.

Lerchenmüller C, Heißenberg J, Damilano F, Bezzeridis VJ, Krämer I, Bochaton-Piallat ML, Hirschberg K, Busch M, Katus HA, Peppel K, Rosenzweig A, Busch H, Boerries M, Most P.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1854-67. doi: 10.1161/ATVBAHA.115.306415. Epub 2016 Jul 7.

47.

A single session of neuromuscular electrical stimulation does not augment postprandial muscle protein accretion.

Dirks ML, Wall BT, Kramer IF, Zorenc AH, Goessens JP, Gijsen AP, van Loon LJ.

Am J Physiol Endocrinol Metab. 2016 Jul 1;311(1):E278-85. doi: 10.1152/ajpendo.00085.2016. Epub 2016 Jun 7.

48.

Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible.

Biosse Duplan M, Komla-Ebri D, Heuzé Y, Estibals V, Gaudas E, Kaci N, Benoist-Lasselin C, Zerah M, Kramer I, Kneissel M, Porta DG, Di Rocco F, Legeai-Mallet L.

Hum Mol Genet. 2016 Jul 15;25(14):2997-3010. Epub 2016 Jun 3.

49.

A saturated SNP linkage map for the orange wheat blossom midge resistance gene Sm1.

Kassa MT, Haas S, Schliephake E, Lewis C, You FM, Pozniak CJ, Krämer I, Perovic D, Sharpe AG, Fobert PR, Koch M, Wise IL, Fenwick P, Berry S, Simmonds J, Hourcade D, Senellart P, Duchalais L, Robert O, Förster J, Thomas JB, Friedt W, Ordon F, Uauy C, McCartney CA.

Theor Appl Genet. 2016 Aug;129(8):1507-17. doi: 10.1007/s00122-016-2720-4. Epub 2016 May 9.

PMID:
27160855
50.

Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction.

Wehmeyer C, Frank S, Beckmann D, Böttcher M, Cromme C, König U, Fennen M, Held A, Paruzel P, Hartmann C, Stratis A, Korb-Pap A, Kamradt T, Kramer I, van den Berg W, Kneissel M, Pap T, Dankbar B.

Sci Transl Med. 2016 Mar 16;8(330):330ra35. doi: 10.1126/scitranslmed.aac4351. Epub 2016 Mar 16.

PMID:
27089204

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