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Items: 1 to 50 of 100

1.

Interaction with the host: the role of fibronectin and extracellular matrix proteins in the adhesion of Gram-negative bacteria.

Vaca DJ, Thibau A, Schütz M, Kraiczy P, Happonen L, Malmström J, Kempf VAJ.

Med Microbiol Immunol. 2019 Nov 29. doi: 10.1007/s00430-019-00644-3. [Epub ahead of print] Review.

PMID:
31784893
2.

Author Correction: Immune evasion of Borrelia miyamotoi: CbiA, a novel outer surface protein exhibiting complement binding and inactivating properties.

Röttgerding F, Wagemakers A, Koetsveld J, Fingerle V, Kirschfink M, Hovius JW, Zipfel PF, Wallich R, Kraiczy P.

Sci Rep. 2019 May 2;9(1):7056. doi: 10.1038/s41598-019-42948-7.

3.

Further Insights Into the Interaction of Human and Animal Complement Regulator Factor H With Viable Lyme Disease Spirochetes.

Mühleip JJ, Lin YP, Kraiczy P.

Front Vet Sci. 2019 Jan 31;5:346. doi: 10.3389/fvets.2018.00346. eCollection 2018.

4.

Combination of microbiome analysis and serodiagnostics to assess the risk of pathogen transmission by ticks to humans and animals in central Germany.

Regier Y, Komma K, Weigel M, Kraiczy P, Laisi A, Pulliainen AT, Hain T, Kempf VAJ.

Parasit Vectors. 2019 Jan 7;12(1):11. doi: 10.1186/s13071-018-3240-7.

5.

Blood treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts.

Marcinkiewicz AL, Dupuis AP 2nd, Zamba-Campero M, Nowak N, Kraiczy P, Ram S, Kramer LD, Lin YP.

Cell Microbiol. 2019 Feb;21(2):e12998. doi: 10.1111/cmi.12998. Epub 2019 Jan 7.

PMID:
30571845
6.

Inter- and intraspecies-specific adhesion of Lyme borreliae to human keratinocytes.

Bigelmayr S, Koenigs A, Kraiczy P.

Ticks Tick Borne Dis. 2019 Jan;10(1):207-212. doi: 10.1016/j.ttbdis.2018.10.006. Epub 2018 Oct 28.

PMID:
30391124
7.

Crystal structure of the membrane attack complex assembly inhibitor BGA71 from the Lyme disease agent Borrelia bavariensis.

Brangulis K, Akopjana I, Petrovskis I, Kazaks A, Kraiczy P, Tars K.

Sci Rep. 2018 Jul 26;8(1):11286. doi: 10.1038/s41598-018-29651-9.

8.

Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission.

Hart T, Nguyen NTT, Nowak NA, Zhang F, Linhardt RJ, Diuk-Wasser M, Ram S, Kraiczy P, Lin YP.

PLoS Pathog. 2018 May 29;14(5):e1007106. doi: 10.1371/journal.ppat.1007106. eCollection 2018 May.

9.

Eliminating Factor H-Binding Activity of Borrelia burgdorferi CspZ Combined with Virus-Like Particle Conjugation Enhances Its Efficacy as a Lyme Disease Vaccine.

Marcinkiewicz AL, Lieknina I, Kotelovica S, Yang X, Kraiczy P, Pal U, Lin YP, Tars K.

Front Immunol. 2018 Feb 8;9:181. doi: 10.3389/fimmu.2018.00181. eCollection 2018.

10.

The Complement Binding and Inhibitory Protein CbiA of Borrelia miyamotoi Degrades Extracellular Matrix Components by Interacting with Plasmin(ogen).

Nguyen NTT, Röttgerding F, Devraj G, Lin YP, Koenigs A, Kraiczy P.

Front Cell Infect Microbiol. 2018 Feb 2;8:23. doi: 10.3389/fcimb.2018.00023. eCollection 2018.

11.

Identification and Characterization of Borrelia burgdorferi Complement-Binding Proteins.

Kraiczy P.

Methods Mol Biol. 2018;1690:95-103. doi: 10.1007/978-1-4939-7383-5_8.

PMID:
29032539
12.

Corrigendum: There is inadequate evidence to support the division of the genus Borrelia.

Margos G, Marosevic D, Cutler S, Derdakova M, Diuk-Wasser M, Emler S, Fish D, Gray J, Hunfeld KP, Jaulhac B, Kahl O, Kovalev S, Kraiczy P, Lane RS, Lienhard R, Lindgren PE, Ogden NH, Ornstein K, Rupprecht T, Schwartz I, Sing A, Straubinger RK, Strle F, Voordouw M, Rizzoli A, Stevenson B, Fingerle V.

Int J Syst Evol Microbiol. 2017 Jun;67(6):2073. doi: 10.1099/ijsem.0.002100. No abstract available.

PMID:
28665266
13.

Immune evasion of Borrelia miyamotoi: CbiA, a novel outer surface protein exhibiting complement binding and inactivating properties.

Röttgerding F, Wagemakers A, Koetsveld J, Fingerle V, Kirschfink M, Hovius JW, Zipfel PF, Wallich R, Kraiczy P.

Sci Rep. 2017 Mar 22;7(1):303. doi: 10.1038/s41598-017-00412-4. Erratum in: Sci Rep. 2019 May 2;9(1):7056.

14.

There Is a Method to the Madness: Strategies to Study Host Complement Evasion by Lyme Disease and Relapsing Fever Spirochetes.

Marcinkiewicz AL, Kraiczy P, Lin YP.

Front Microbiol. 2017 Mar 2;8:328. doi: 10.3389/fmicb.2017.00328. eCollection 2017. Review.

15.

There is inadequate evidence to support the division of the genus Borrelia.

Margos G, Marosevic D, Cutler S, Derdakova M, Diuk-Wasser M, Emler S, Fish D, Gray J, Hunfeldt KP, Jaulhac B, Kahl O, Kovalev S, Kraiczy P, Lane RS, Lienhard R, Lindgren PE, Ogden N, Ornstein K, Rupprecht T, Schwartz I, Sing A, Straubinger RK, Strle F, Voordouw M, Rizzoli A, Stevenson B, Fingerle V.

Int J Syst Evol Microbiol. 2017 Apr;67(4):1081-1084. doi: 10.1099/ijsem.0.001717. Epub 2017 May 5. No abstract available. Erratum in: Int J Syst Evol Microbiol. 2017 Jun;67(6):2073.

PMID:
27930271
16.

Hide and Seek: How Lyme Disease Spirochetes Overcome Complement Attack.

Kraiczy P.

Front Immunol. 2016 Sep 26;7:385. eCollection 2016. Review.

17.

Travelling between Two Worlds: Complement as a Gatekeeper for an Expanded Host Range of Lyme Disease Spirochetes.

Kraiczy P.

Vet Sci. 2016 Jun 14;3(2). pii: E12. doi: 10.3390/vetsci3020012. Review.

18.

Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Diverse Origin Target the Human Terminal Complement Inhibitor Vitronectin via a Single Common Motif.

Hallström T, Singh B, Kraiczy P, Hammerschmidt S, Skerka C, Zipfel PF, Riesbeck K.

PLoS One. 2016 Jan 25;11(1):e0147709. doi: 10.1371/journal.pone.0147709. eCollection 2016.

19.

CipA of Acinetobacter baumannii Is a Novel Plasminogen Binding and Complement Inhibitory Protein.

Koenigs A, Stahl J, Averhoff B, Göttig S, Wichelhaus TA, Wallich R, Zipfel PF, Kraiczy P.

J Infect Dis. 2016 May 1;213(9):1388-99. doi: 10.1093/infdis/jiv601. Epub 2015 Dec 17.

PMID:
26681776
20.

Occurrence of Borrelia burgdorferi s.l. in different genera of mosquitoes (Culicidae) in Central Europe.

Melaun C, Zotzmann S, Santaella VG, Werblow A, Zumkowski-Xylander H, Kraiczy P, Klimpel S.

Ticks Tick Borne Dis. 2016 Mar;7(2):256-63. doi: 10.1016/j.ttbdis.2015.10.018. Epub 2015 Nov 12.

PMID:
26631488
21.

BGA66 and BGA71 facilitate complement resistance of Borrelia bavariensis by inhibiting assembly of the membrane attack complex.

Hammerschmidt C, Klevenhaus Y, Koenigs A, Hallström T, Fingerle V, Skerka C, Pos KM, Zipfel PF, Wallich R, Kraiczy P.

Mol Microbiol. 2016 Jan;99(2):407-24. doi: 10.1111/mmi.13239. Epub 2015 Oct 27.

22.

Correction: Translation Elongation Factor Tuf of Acinetobacter baumannii Is a Plasminogen-Binding Protein.

Koenigs A, Zipfel PF, Kraiczy P.

PLoS One. 2015 Sep 14;10(9):e0138398. doi: 10.1371/journal.pone.0138398. eCollection 2015. No abstract available.

23.

Translation Elongation Factor Tuf of Acinetobacter baumannii Is a Plasminogen-Binding Protein.

Koenigs A, Zipfel PF, Kraiczy P.

PLoS One. 2015 Jul 31;10(7):e0134418. doi: 10.1371/journal.pone.0134418. eCollection 2015. Erratum in: PLoS One. 2015;10(9):e0138398.

24.

Interferon-α curbs production of interleukin-22 by human peripheral blood mononuclear cells exposed to live Borrelia burgdorferi.

Berner A, Bachmann M, Pfeilschifter J, Kraiczy P, Mühl H.

J Cell Mol Med. 2015 Oct;19(10):2507-11. doi: 10.1111/jcmm.12634. Epub 2015 Jul 8.

25.

A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity.

Hammer C, Wanitchakool P, Sirianant L, Papiol S, Monnheimer M, Faria D, Ousingsawat J, Schramek N, Schmitt C, Margos G, Michel A, Kraiczy P, Pawlita M, Schreiber R, Schulz TF, Fingerle V, Tumani H, Ehrenreich H, Kunzelmann K.

Mol Med. 2015 Feb 23;21:26-37. doi: 10.2119/molmed.2014.00219.

26.

The relapsing fever spirochete Borrelia miyamotoi resists complement-mediated killing by human serum.

Teegler A, Herzberger P, Margos G, Fingerle V, Kraiczy P.

Ticks Tick Borne Dis. 2014 Oct;5(6):898-901. doi: 10.1016/j.ttbdis.2014.07.011. Epub 2014 Jul 22.

PMID:
25104575
27.

Versatile roles of CspA orthologs in complement inactivation of serum-resistant Lyme disease spirochetes.

Hammerschmidt C, Koenigs A, Siegel C, Hallström T, Skerka C, Wallich R, Zipfel PF, Kraiczy P.

Infect Immun. 2014 Jan;82(1):380-92. doi: 10.1128/IAI.01094-13. Epub 2013 Nov 4.

28.

CspA from Borrelia burgdorferi inhibits the terminal complement pathway.

Hallström T, Siegel C, Mörgelin M, Kraiczy P, Skerka C, Zipfel PF.

MBio. 2013 Aug 13;4(4). pii: e00481-13. doi: 10.1128/mBio.00481-13.

29.

BBA70 of Borrelia burgdorferi is a novel plasminogen-binding protein.

Koenigs A, Hammerschmidt C, Jutras BL, Pogoryelov D, Barthel D, Skerka C, Kugelstadt D, Wallich R, Stevenson B, Zipfel PF, Kraiczy P.

J Biol Chem. 2013 Aug 30;288(35):25229-43. doi: 10.1074/jbc.M112.413872. Epub 2013 Jul 16.

30.

Further structural insights into the binding of complement factor H by complement regulator-acquiring surface protein 1 (CspA) of Borrelia burgdorferi.

Caesar JJ, Wallich R, Kraiczy P, Zipfel PF, Lea SM.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):629-33. doi: 10.1107/S1744309113012748. Epub 2013 May 23.

31.

ErpC, a member of the complement regulator-acquiring family of surface proteins from Borrelia burgdorferi, possesses an architecture previously unseen in this protein family.

Caesar JJ, Johnson S, Kraiczy P, Lea SM.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):624-8. doi: 10.1107/S1744309113013249. Epub 2013 May 23.

32.

Prevalences of tick-borne encephalitis virus and Borrelia burgdorferi sensu lato in Ixodes ricinus populations of the Rhine-Main region, Germany.

Bingsohn L, Beckert A, Zehner R, Kuch U, Oehme R, Kraiczy P, Amendt J.

Ticks Tick Borne Dis. 2013 Apr;4(3):207-13. doi: 10.1016/j.ttbdis.2012.11.012. Epub 2013 Feb 14.

PMID:
23415373
33.

Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components.

Schwab J, Hammerschmidt C, Richter D, Skerka C, Matuschka FR, Wallich R, Zipfel PF, Kraiczy P.

PLoS One. 2013;8(1):e53659. doi: 10.1371/journal.pone.0053659. Epub 2013 Jan 8.

34.

Complement regulator-acquiring surface proteins of Borrelia burgdorferi: Structure, function and regulation of gene expression.

Kraiczy P, Stevenson B.

Ticks Tick Borne Dis. 2013 Feb;4(1-2):26-34. doi: 10.1016/j.ttbdis.2012.10.039. Epub 2012 Nov 10. Review.

35.

Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b.

Koch TK, Reuter M, Barthel D, Böhm S, van den Elsen J, Kraiczy P, Zipfel PF, Skerka C.

PLoS One. 2012;7(10):e47638. doi: 10.1371/journal.pone.0047638. Epub 2012 Oct 11.

36.

Contribution of the infection-associated complement regulator-acquiring surface protein 4 (ErpC) to complement resistance of Borrelia burgdorferi.

Hammerschmidt C, Hallström T, Skerka C, Wallich R, Stevenson B, Zipfel PF, Kraiczy P.

Clin Dev Immunol. 2012;2012:349657. doi: 10.1155/2012/349657. Epub 2012 Jan 30.

37.

Whole-genome sequences of Borrelia bissettii, Borrelia valaisiana, and Borrelia spielmanii.

Schutzer SE, Fraser-Liggett CM, Qiu WG, Kraiczy P, Mongodin EF, Dunn JJ, Luft BJ, Casjens SR.

J Bacteriol. 2012 Jan;194(2):545-6. doi: 10.1128/JB.06263-11.

38.

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1.

Bachmann M, Horn K, Rudloff I, Goren I, Holdener M, Christen U, Darsow N, Hunfeld KP, Koehl U, Kind P, Pfeilschifter J, Kraiczy P, Mühl H.

PLoS Pathog. 2010 Oct 14;6(10):e1001144. doi: 10.1371/journal.ppat.1001144.

39.

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi.

Siegel C, Hallström T, Skerka C, Eberhardt H, Uzonyi B, Beckhaus T, Karas M, Wallich R, Stevenson B, Zipfel PF, Kraiczy P.

PLoS One. 2010 Oct 20;5(10):e13519. doi: 10.1371/journal.pone.0013519.

40.

Inadequate binding of immune regulator factor H is associated with sensitivity of Borrelia lusitaniae to human complement.

Dieterich R, Hammerschmidt C, Richter D, Skerka C, Wallich R, Matuschka FR, Zipfel PF, Kraiczy P.

Infect Immun. 2010 Nov;78(11):4467-76. doi: 10.1128/IAI.00138-10. Epub 2010 Sep 7.

41.

Complement regulator-acquiring surface protein 1 of Borrelia burgdorferi binds to human bone morphogenic protein 2, several extracellular matrix proteins, and plasminogen.

Hallström T, Haupt K, Kraiczy P, Hortschansky P, Wallich R, Skerka C, Zipfel PF.

J Infect Dis. 2010 Aug 15;202(3):490-8. doi: 10.1086/653825.

PMID:
20565259
42.

Molecular characterization of the interaction of Borrelia parkeri and Borrelia turicatae with human complement regulators.

Schott M, Grosskinsky S, Brenner C, Kraiczy P, Wallich R.

Infect Immun. 2010 May;78(5):2199-208. doi: 10.1128/IAI.00089-10. Epub 2010 Mar 15.

43.

Comparison of in vitro activities of tigecycline, doxycycline, and tetracycline against the spirochete Borrelia burgdorferi.

Ates L, Hanssen-Hübner C, Norris DE, Richter D, Kraiczy P, Hunfeld KP.

Ticks Tick Borne Dis. 2010 Mar;1(1):30-4. doi: 10.1016/j.ttbdis.2009.11.004. Epub 2010 Jan 7.

PMID:
21771509
44.

Identification and functional characterisation of Complement Regulator Acquiring Surface Protein-1 of serum resistant Borrelia garinii OspA serotype 4.

van Burgel ND, Kraiczy P, Schuijt TJ, Zipfel PF, van Dam AP.

BMC Microbiol. 2010 Feb 10;10:43. doi: 10.1186/1471-2180-10-43.

45.

The borrelial fibronectin-binding protein RevA is an early antigen of human Lyme disease.

Brissette CA, Rossmann E, Bowman A, Cooley AE, Riley SP, Hunfeld KP, Bechtel M, Kraiczy P, Stevenson B.

Clin Vaccine Immunol. 2010 Feb;17(2):274-80. doi: 10.1128/CVI.00437-09. Epub 2009 Dec 23.

46.

Functional characterization of Borrelia spielmanii outer surface proteins that interact with distinct members of the human factor H protein family and with plasminogen.

Seling A, Siegel C, Fingerle V, Jutras BL, Brissette CA, Skerka C, Wallich R, Zipfel PF, Stevenson B, Kraiczy P.

Infect Immun. 2010 Jan;78(1):39-48. doi: 10.1128/IAI.00691-09. Epub 2009 Oct 26.

47.

CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi.

Kenedy MR, Vuppala SR, Siegel C, Kraiczy P, Akins DR.

Infect Immun. 2009 Jul;77(7):2773-82. doi: 10.1128/IAI.00318-09. Epub 2009 May 18.

48.

When is the best time to order a Western blot and how should it be interpreted?

Hunfeld KP, Kraiczy P.

Curr Probl Dermatol. 2009;37:167-177. doi: 10.1159/000213074. Epub 2009 Apr 8.

PMID:
19367101
49.

Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity.

Grosskinsky S, Schott M, Brenner C, Cutler SJ, Kraiczy P, Zipfel PF, Simon MM, Wallich R.

PLoS One. 2009;4(3):e4858. doi: 10.1371/journal.pone.0004858. Epub 2009 Mar 24.

50.

Mutational analyses of the BbCRASP-1 protein of Borrelia burgdorferi identify residues relevant for the architecture and binding of host complement regulators FHL-1 and factor H.

Kraiczy P, Hanssen-Hübner C, Kitiratschky V, Brenner C, Besier S, Brade V, Simon MM, Skerka C, Roversi P, Lea SM, Stevenson B, Wallich R, Zipfel PF.

Int J Med Microbiol. 2009 Apr;299(4):255-68. doi: 10.1016/j.ijmm.2008.09.002. Epub 2009 Jan 9.

PMID:
19138559

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