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Items: 13


Blimp-1 Rather Than Hobit Drives the Formation of Tissue-Resident Memory CD8+ T Cells in the Lungs.

Behr FM, Kragten NAM, Wesselink TH, Nota B, van Lier RAW, Amsen D, Stark R, Hombrink P, van Gisbergen KPJM.

Front Immunol. 2019 Mar 7;10:400. doi: 10.3389/fimmu.2019.00400. eCollection 2019.


T RM maintenance is regulated by tissue damage via P2RX7.

Stark R, Wesselink TH, Behr FM, Kragten NAM, Arens R, Koch-Nolte F, van Gisbergen KPJM, van Lier RAW.

Sci Immunol. 2018 Dec 14;3(30). pii: eaau1022. doi: 10.1126/sciimmunol.aau1022.


Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells.

Kragten NAM, Behr FM, Vieira Braga FA, Remmerswaal EBM, Wesselink TH, Oja AE, Hombrink P, Kallies A, van Lier RAW, Stark R, van Gisbergen KPJM.

Eur J Immunol. 2018 Oct;48(10):1644-1662. doi: 10.1002/eji.201847771. Epub 2018 Aug 16.


Memory CD8+ T cells support the maintenance of hematopoietic stem cells in the bone marrow.

Geerman S, Brasser G, Bhushal S, Salerno F, Kragten NA, Hoogenboezem M, de Haan G, Wolkers MC, Pascutti MF, Nolte MA.

Haematologica. 2018 Jun;103(6):e230-e233. doi: 10.3324/haematol.2017.169516. Epub 2018 Feb 22. No abstract available.


The Transcription Factor Hobit Identifies Human Cytotoxic CD4+ T Cells.

Oja AE, Vieira Braga FA, Remmerswaal EB, Kragten NA, Hertoghs KM, Zuo J, Moss PA, van Lier RA, van Gisbergen KP, Hombrink P.

Front Immunol. 2017 Mar 24;8:325. doi: 10.3389/fimmu.2017.00325. eCollection 2017.


The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells.

Chang GW, Hsiao CC, Peng YM, Vieira Braga FA, Kragten NA, Remmerswaal EB, van de Garde MD, Straussberg R, König GM, Kostenis E, Knäuper V, Meyaard L, van Lier RA, van Gisbergen KP, Lin HH, Hamann J.

Cell Rep. 2016 May 24;15(8):1757-70. doi: 10.1016/j.celrep.2016.04.053. Epub 2016 May 12.


Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.

Mackay LK, Minnich M, Kragten NA, Liao Y, Nota B, Seillet C, Zaid A, Man K, Preston S, Freestone D, Braun A, Wynne-Jones E, Behr FM, Stark R, Pellicci DG, Godfrey DI, Belz GT, Pellegrini M, Gebhardt T, Busslinger M, Shi W, Carbone FR, van Lier RA, Kallies A, van Gisbergen KP.

Science. 2016 Apr 22;352(6284):459-63. doi: 10.1126/science.aad2035.


Blimp-1 homolog Hobit identifies effector-type lymphocytes in humans.

Vieira Braga FA, Hertoghs KM, Kragten NA, Doody GM, Barnes NA, Remmerswaal EB, Hsiao CC, Moerland PD, Wouters D, Derks IA, van Stijn A, Demkes M, Hamann J, Eldering E, Nolte MA, Tooze RM, ten Berge IJ, van Gisbergen KP, van Lier RA.

Eur J Immunol. 2015 Oct;45(10):2945-58. doi: 10.1002/eji.201545650. Epub 2015 Sep 7.


Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation.

van Gisbergen KP, Kragten NA, Hertoghs KM, Wensveen FM, Jonjic S, Hamann J, Nolte MA, van Lier RA.

Nat Immunol. 2012 Sep;13(9):864-71. doi: 10.1038/ni.2393. Epub 2012 Aug 12.


Analysis of stem-cell-like properties of human CD161++IL-18Rα+ memory CD8+ T cells.

Havenith SH, Yong SL, Henson SM, Piet B, Idu MM, Koch SD, Jonkers RE, Kragten NA, Akbar AN, van Lier RA, ten Berge IJ.

Int Immunol. 2012 Oct;24(10):625-36. Epub 2012 Jul 26.


CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.

Wensveen FM, Unger PP, Kragten NA, Derks IA, ten Brinke A, Arens R, van Lier RA, Eldering E, van Gisbergen KP.

J Immunol. 2012 May 1;188(9):4256-67. doi: 10.4049/jimmunol.1102889. Epub 2012 Mar 26.


The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants.

van Gisbergen KP, Klarenbeek PL, Kragten NA, Unger PP, Nieuwenhuis MB, Wensveen FM, ten Brinke A, Tak PP, Eldering E, Nolte MA, van Lier RA.

Immunity. 2011 Jul 22;35(1):97-108. doi: 10.1016/j.immuni.2011.04.020. Epub 2011 Jul 14.


Chronic CD70-driven costimulation impairs IgG responses by instructing T cells to inhibit germinal center B cell formation through FasL-Fas interactions.

Beishuizen CR, Kragten NA, Boon L, Nolte MA, van Lier RA, van Gisbergen KP.

J Immunol. 2009 Nov 15;183(10):6442-51. doi: 10.4049/jimmunol.0901565. Epub 2009 Oct 28.

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