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Items: 1 to 50 of 254

1.

Splenic volume differentiates complicated and non-complicated celiac disease.

van Gils T, Nijeboer P, van Waesberghe JHT, Coupé VM, Janssen K, Zegers JA, Nurmohamed SA, Kraal G, Jiskoot SC, Bouma G, Mulder CJ.

United European Gastroenterol J. 2017 Apr;5(3):374-379. doi: 10.1177/2050640616663571. Epub 2016 Aug 17.

2.

Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency.

Szilagyi K, Gazendam RP, van Hamme JL, Tool AT, van Houdt M, Vos WA, Verkuijlen P, Janssen H, Belot A, Juillard L, Förster-Waldl E, Boztug K, Kraal G, de Winther MP, Kuijpers TW, van den Berg TK.

J Allergy Clin Immunol. 2015 Nov;136(5):1404-7.e1-10. doi: 10.1016/j.jaci.2015.06.016. Epub 2015 Jul 30. No abstract available.

PMID:
26233929
3.

Intestinal epithelial cell transported TLR2 ligand stimulates Ly6C⁺ monocyte differentiation in a G-CSF dependent manner.

Hiemstra IH, Vrijland K, Hogenboom MM, Bouma G, Kraal G, den Haan JM.

Immunobiology. 2015 Nov;220(11):1255-65. doi: 10.1016/j.imbio.2015.06.015. Epub 2015 Jun 26.

PMID:
26143228
4.

Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells.

Klaver EJ, van der Pouw Kraan TC, Laan LC, Kringel H, Cummings RD, Bouma G, Kraal G, van Die I.

Genes Immun. 2015 Sep;16(6):378-87. doi: 10.1038/gene.2015.18. Epub 2015 May 21.

PMID:
25996526
5.

Moh Daha, the organizer.

Kraal G.

Mol Immunol. 2015 Nov;68(1):49. doi: 10.1016/j.molimm.2015.04.020. Epub 2015 May 14. No abstract available.

PMID:
25982930
6.

Dectin-1 deficiency does not affect atherosclerosis development in mice.

Szilagyi K, Gijbels MJ, van der Velden S, Heinsbroek SE, Kraal G, de Winther MP, van den Berg TK.

Atherosclerosis. 2015 Apr;239(2):318-21. doi: 10.1016/j.atherosclerosis.2015.02.005. Epub 2015 Feb 7.

7.

HLA-DRB1*03:01 and HLA-DRB1*04:01 modify the presentation and outcome in autoimmune hepatitis type-1.

van Gerven NM, de Boer YS, Zwiers A, Verwer BJ, Drenth JP, van Hoek B, van Erpecum KJ, Beuers U, van Buuren HR, den Ouden JW, Verdonk RC, Koek GH, Brouwer JT, Guichelaar MM, Vrolijk JM, Coenraad MJ, Kraal G, Mulder CJ, van Nieuwkerk CM, Bloemena E, Verspaget HW, Kumar V, Zhernakova A, Wijmenga C, Franke L, Bouma G; Dutch Autoimmune Hepatitis Study Group.

Genes Immun. 2015 Jun;16(4):247-52. doi: 10.1038/gene.2014.82. Epub 2015 Jan 22.

PMID:
25611558
8.

Antigen targeting reveals splenic CD169+ macrophages as promoters of germinal center B-cell responses.

Veninga H, Borg EG, Vreeman K, Taylor PR, Kalay H, van Kooyk Y, Kraal G, Martinez-Pomares L, den Haan JM.

Eur J Immunol. 2015 Mar;45(3):747-57. doi: 10.1002/eji.201444983. Epub 2015 Jan 14. Erratum in: Eur J Immunol. 2016 Feb;46(2):493.

9.

PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages.

Szilagyi K, Meijer AB, Neele AE, Verkuijlen P, Leitges M, Dabernat S, Förster-Waldl E, Boztug K, Belot A, Kuijpers TW, Kraal G, de Winther MP, van den Berg TK.

Cardiovasc Res. 2014 Dec 1;104(3):467-76. doi: 10.1093/cvr/cvu213. Epub 2014 Sep 24.

PMID:
25253077
10.

Human buccal epithelium acquires microbial hyporesponsiveness at birth, a role for secretory leukocyte protease inhibitor.

Menckeberg CL, Hol J, Simons-Oosterhuis Y, Raatgeep HR, de Ruiter LF, Lindenbergh-Kortleve DJ, Korteland-van Male AM, El Aidy S, van Lierop PP, Kleerebezem M, Groeneweg M, Kraal G, Elink-Schuurman BE, de Jongste JC, Nieuwenhuis EE, Samsom JN.

Gut. 2015 Jun;64(6):884-93. doi: 10.1136/gutjnl-2013-306149. Epub 2014 Jul 23.

PMID:
25056659
11.

The identification and developmental requirements of colonic CD169⁺ macrophages.

Hiemstra IH, Beijer MR, Veninga H, Vrijland K, Borg EG, Olivier BJ, Mebius RE, Kraal G, den Haan JM.

Immunology. 2014 Jun;142(2):269-78. doi: 10.1111/imm.12251.

12.

Vitamin A and dendritic cell differentiation.

Beijer MR, Kraal G, den Haan JM.

Immunology. 2014 May;142(1):39-45. doi: 10.1111/imm.12228. Review.

13.

Genome-wide association study identifies variants associated with autoimmune hepatitis type 1.

de Boer YS, van Gerven NM, Zwiers A, Verwer BJ, van Hoek B, van Erpecum KJ, Beuers U, van Buuren HR, Drenth JP, den Ouden JW, Verdonk RC, Koek GH, Brouwer JT, Guichelaar MM, Vrolijk JM, Kraal G, Mulder CJ, van Nieuwkerk CM, Fischer J, Berg T, Stickel F, Sarrazin C, Schramm C, Lohse AW, Weiler-Normann C, Lerch MM, Nauck M, Völzke H, Homuth G, Bloemena E, Verspaget HW, Kumar V, Zhernakova A, Wijmenga C, Franke L, Bouma G; Dutch Autoimmune Hepatitis Study Group; LifeLines Cohort Study; Study of Health in Pomerania.

Gastroenterology. 2014 Aug;147(2):443-52.e5. doi: 10.1053/j.gastro.2014.04.022. Epub 2014 Apr 23.

PMID:
24768677
14.

Excreted/secreted Trichuris suis products reduce barrier function and suppress inflammatory cytokine production of intestinal epithelial cells.

Hiemstra IH, Klaver EJ, Vrijland K, Kringel H, Andreasen A, Bouma G, Kraal G, van Die I, den Haan JM.

Mol Immunol. 2014 Jul;60(1):1-7. doi: 10.1016/j.molimm.2014.03.003. Epub 2014 Apr 2.

PMID:
24705296
15.

Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis.

Wolfs IM, Stöger JL, Goossens P, Pöttgens C, Gijbels MJ, Wijnands E, van der Vorst EP, van Gorp P, Beckers L, Engel D, Biessen EA, Kraal G, van Die I, Donners MM, de Winther MP.

FASEB J. 2014 Jan;28(1):288-99. doi: 10.1096/fj.13-235911. Epub 2013 Sep 16.

PMID:
24043262
16.

Cytotoxic T lymphocyte antigen-4 +49A/G polymorphism does not affect susceptibility to autoimmune hepatitis.

van Gerven NM, de Boer YS, Zwiers A, van Hoek B, van Erpecum KJ, Beuers U, van Buuren HR, Drenth JP, den Ouden JW, Verdonk RC, Koek GH, Brouwer JT, Guichelaar MM, Vrolijk JM, Kraal G, Mulder CJ, van Nieuwkerk CM, Bouma G; Dutch Autoimmune Hepatitis Study group.

Liver Int. 2013 Aug;33(7):1039-43. doi: 10.1111/liv.12157. Epub 2013 Mar 31.

PMID:
23551963
17.

A crucial role for retinoic acid in the development of Notch-dependent murine splenic CD8- CD4- and CD4+ dendritic cells.

Beijer MR, Molenaar R, Goverse G, Mebius RE, Kraal G, den Haan JM.

Eur J Immunol. 2013 Jun;43(6):1608-16. doi: 10.1002/eji.201343325. Epub 2013 Apr 27.

18.

Thiopurine treatment in patients with Crohn's disease leads to a selective reduction of an effector cytotoxic gene expression signature revealed by whole-genome expression profiling.

Bouma G, Baggen JM, van Bodegraven AA, Mulder CJ, Kraal G, Zwiers A, Horrevoets AJ, van der Pouw Kraan CT.

Mol Immunol. 2013 Jul;54(3-4):472-81. doi: 10.1016/j.molimm.2013.01.015. Epub 2013 Feb 27.

PMID:
23454163
19.

Trichuris suis-induced modulation of human dendritic cell function is glycan-mediated.

Klaver EJ, Kuijk LM, Laan LC, Kringel H, van Vliet SJ, Bouma G, Cummings RD, Kraal G, van Die I.

Int J Parasitol. 2013 Mar;43(3-4):191-200. doi: 10.1016/j.ijpara.2012.10.021. Epub 2012 Dec 7.

PMID:
23220043
20.

SIRPα controls the activity of the phagocyte NADPH oxidase by restricting the expression of gp91(phox).

van Beek EM, Zarate JA, van Bruggen R, Schornagel K, Tool AT, Matozaki T, Kraal G, Roos D, van den Berg TK.

Cell Rep. 2012 Oct 25;2(4):748-55. doi: 10.1016/j.celrep.2012.08.027. Epub 2012 Sep 27.

21.

Genetic variations in interleukin-12 related genes in immune-mediated diseases.

van Wanrooij RL, Zwiers A, Kraal G, Bouma G.

J Autoimmun. 2012 Dec;39(4):359-68. doi: 10.1016/j.jaut.2012.06.002. Epub 2012 Jul 18. Review.

PMID:
22819329
22.

Stromal cells of the mouse spleen.

den Haan JM, Mebius RE, Kraal G.

Front Immunol. 2012 Jul 12;3:201. doi: 10.3389/fimmu.2012.00201. eCollection 2012.

23.

Nod2 improves barrier function of intestinal epithelial cells via enhancement of TLR responses.

Hiemstra IH, Bouma G, Geerts D, Kraal G, den Haan JM.

Mol Immunol. 2012 Oct;52(3-4):264-72. doi: 10.1016/j.molimm.2012.06.007. Epub 2012 Jun 27.

PMID:
22750073
24.

Defective IL-1A expression in patients with Crohn's disease is related to attenuated MAP3K4 signaling.

van der Pouw Kraan CT, Baggen JM, van Bodegraven AA, Mulder CJ, Zwiers A, Geerts D, Kraal G, Horrevoets AJ, Bouma G.

Hum Immunol. 2012 Sep;73(9):912-9. doi: 10.1016/j.humimm.2012.06.004. Epub 2012 Jun 22.

PMID:
22732089
25.

Soluble helminth products suppress clinical signs in murine experimental autoimmune encephalomyelitis and differentially modulate human dendritic cell activation.

Kuijk LM, Klaver EJ, Kooij G, van der Pol SM, Heijnen P, Bruijns SC, Kringel H, Pinelli E, Kraal G, de Vries HE, Dijkstra CD, Bouma G, van Die I.

Mol Immunol. 2012 Jun;51(2):210-8. doi: 10.1016/j.molimm.2012.03.020. Epub 2012 Apr 5.

PMID:
22482518
26.

Innate immune functions of macrophage subpopulations in the spleen.

den Haan JM, Kraal G.

J Innate Immun. 2012;4(5-6):437-45. doi: 10.1159/000335216. Epub 2012 Feb 7. Review.

27.

Cutting edge: a variant of the IL-23R gene associated with inflammatory bowel disease induces loss of microRNA regulation and enhanced protein production.

Zwiers A, Kraal L, van de Pouw Kraan TC, Wurdinger T, Bouma G, Kraal G.

J Immunol. 2012 Feb 15;188(4):1573-7. doi: 10.4049/jimmunol.1101494. Epub 2012 Jan 18.

28.

CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction.

Zhao XW, van Beek EM, Schornagel K, Van der Maaden H, Van Houdt M, Otten MA, Finetti P, Van Egmond M, Matozaki T, Kraal G, Birnbaum D, van Elsas A, Kuijpers TW, Bertucci F, van den Berg TK.

Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18342-7. doi: 10.1073/pnas.1106550108. Epub 2011 Oct 31.

29.

Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis.

Schwandt T, Schumak B, Gielen GH, Jüngerkes F, Schmidbauer P, Klocke K, Staratschek-Jox A, van Rooijen N, Kraal G, Ludwig-Portugall I, Franken L, Wehner S, Kalff JC, Weber O, Kirschning C, Coch C, Kalinke U, Wenzel J, Kurts C, Zawatzky R, Holzmann B, Layland L, Schultze JL, Burgdorf S, den Haan JM, Knolle PA, Limmer A.

EMBO J. 2012 Jan 4;31(1):201-13. doi: 10.1038/emboj.2011.380. Epub 2011 Oct 28.

30.

CD62L(neg)CD38⁺ expression on circulating CD4⁺ T cells identifies mucosally differentiated cells in protein fed mice and in human celiac disease patients and controls.

du Pré MF, van Berkel LA, Ráki M, van Leeuwen MA, de Ruiter LF, Broere F, Ter Borg MN, Lund FE, Escher JC, Lundin KE, Sollid LM, Kraal G, Nieuwenhuis EE, Samsom JN.

Am J Gastroenterol. 2011 Jun;106(6):1147-59. doi: 10.1038/ajg.2011.24. Epub 2011 Mar 8.

31.

A polymorphism in the coding region of Il12b promotes IL-12p70 and IL-23 heterodimer formation.

Zwiers A, Fuss IJ, Seegers D, Konijn T, Garcia-Vallejo JJ, Samsom JN, Strober W, Kraal G, Bouma G.

J Immunol. 2011 Mar 15;186(6):3572-80. doi: 10.4049/jimmunol.1001330. Epub 2011 Feb 14.

32.

The production of secretory leukocyte protease inhibitor by dendritic cells.

Vroling AB, Konijn T, Samsom JN, Kraal G.

Mol Immunol. 2011 Jan;48(4):630-6. doi: 10.1016/j.molimm.2010.11.002. Epub 2010 Nov 27.

PMID:
21112636
33.

Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells.

Backer R, Schwandt T, Greuter M, Oosting M, Jüngerkes F, Tüting T, Boon L, O'Toole T, Kraal G, Limmer A, den Haan JM.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):216-21. doi: 10.1073/pnas.0909541107. Epub 2009 Dec 14.

34.

Lymph node stromal cells support dendritic cell-induced gut-homing of T cells.

Molenaar R, Greuter M, van der Marel AP, Roozendaal R, Martin SF, Edele F, Huehn J, Förster R, O'Toole T, Jansen W, Eestermans IL, Kraal G, Mebius RE.

J Immunol. 2009 Nov 15;183(10):6395-402. doi: 10.4049/jimmunol.0900311. Epub 2009 Oct 19.

35.

Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.

van Beek EM, de Vries TJ, Mulder L, Schoenmaker T, Hoeben KA, Matozaki T, Langenbach GE, Kraal G, Everts V, van den Berg TK.

FASEB J. 2009 Dec;23(12):4081-90. doi: 10.1096/fj.09-131557. Epub 2009 Aug 10.

PMID:
19667119
36.

Immunoglobulin A: Fc(alpha)RI interactions induce neutrophil migration through release of leukotriene B4.

van der Steen L, Tuk CW, Bakema JE, Kooij G, Reijerkerk A, Vidarsson G, Bouma G, Kraal G, de Vries HE, Beelen RH, van Egmond M.

Gastroenterology. 2009 Dec;137(6):2018-29.e1-3. doi: 10.1053/j.gastro.2009.06.047. Epub 2009 Jun 23.

PMID:
19555692
37.

LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.

Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE.

J Immunol. 2009 May 1;182(9):5439-45. doi: 10.4049/jimmunol.0801165.

38.

Different mechanisms regulate CD4(+) T cell independent induction of oral and nasal tolerance of CD8(+) T cells.

van den Berg H, Greuter M, Kraal G, den Haan JM.

Immunobiology. 2010;215(2):163-71. doi: 10.1016/j.imbio.2009.01.012. Epub 2009 Mar 10.

PMID:
19278748
39.

Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4.

Broere F, du Pré MF, van Berkel LA, Garssen J, Schmidt-Weber CB, Lambrecht BN, Hendriks RW, Nieuwenhuis EE, Kraal G, Samsom JN.

Mucosal Immunol. 2009 May;2(3):254-64. doi: 10.1038/mi.2009.2. Epub 2009 Mar 4.

PMID:
19262503
40.

Acute experimental colitis and human chronic inflammatory diseases share expression of inflammation-related genes with conserved Ets2 binding sites.

van der Pouw Kraan TC, Zwiers A, Mulder CJ, Kraal G, Bouma G.

Inflamm Bowel Dis. 2009 Feb;15(2):224-35. doi: 10.1002/ibd.20747.

PMID:
18942749
41.

Increased expression of the tight junction molecule claudin-18 A1 in both experimental colitis and ulcerative colitis.

Zwiers A, Fuss IJ, Leijen S, Mulder CJ, Kraal G, Bouma G.

Inflamm Bowel Dis. 2008 Dec;14(12):1652-9. doi: 10.1002/ibd.20695.

PMID:
18831034
42.

The conduit system of the lymph node.

Roozendaal R, Mebius RE, Kraal G.

Int Immunol. 2008 Dec;20(12):1483-7. doi: 10.1093/intimm/dxn110. Epub 2008 Sep 29. Review.

PMID:
18824503
43.

Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner.

Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R.

J Leukoc Biol. 2008 Jul;84(1):152-61. doi: 10.1189/jlb.0907659. Epub 2008 Apr 10.

PMID:
18403646
44.

The effect of NOD2 activation on TLR2-mediated cytokine responses is dependent on activation dose and NOD2 genotype.

Borm ME, van Bodegraven AA, Mulder CJ, Kraal G, Bouma G.

Genes Immun. 2008 Apr;9(3):274-8. doi: 10.1038/gene.2008.9. Epub 2008 Mar 13.

PMID:
18340358
45.

CD8- dendritic cells preferentially cross-present Saccharomyces cerevisiae antigens.

Backer R, van Leeuwen F, Kraal G, den Haan JM.

Eur J Immunol. 2008 Feb;38(2):370-80. doi: 10.1002/eji.200737647.

46.

Antigens take the shuttle.

Kraal G.

Nat Immunol. 2008 Jan;9(1):11-2. No abstract available.

PMID:
18087249
47.

Secretory leukoprotease inhibitor in mucosal lymph node dendritic cells regulates the threshold for mucosal tolerance.

Samsom JN, van der Marel AP, van Berkel LA, van Helvoort JM, Simons-Oosterhuis Y, Jansen W, Greuter M, Nelissen RL, Meeuwisse CM, Nieuwenhuis EE, Mebius RE, Kraal G.

J Immunol. 2007 Nov 15;179(10):6588-95.

48.

Lymphoid organogenesis in brief.

Vondenhoff MF, Kraal G, Mebius RE.

Eur J Immunol. 2007 Nov;37 Suppl 1:S46-52. Review.

49.

Blockade of IDO inhibits nasal tolerance induction.

van der Marel AP, Samsom JN, Greuter M, van Berkel LA, O'Toole T, Kraal G, Mebius RE.

J Immunol. 2007 Jul 15;179(2):894-900.

50.

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