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Dietary Patterns in New Zealand Women: Evaluating Differences in Body Composition and Metabolic Biomarkers.

Jayasinghe SN, Breier BH, McNaughton SA, Russell AP, Della Gatta PA, Mason S, Stonehouse W, Walsh DCI, Kruger R.

Nutrients. 2019 Jul 18;11(7). pii: E1643. doi: 10.3390/nu11071643.


Connecting environmental exposure and neurodegeneration using cheminformatics and high resolution mass spectrometry: potential and challenges.

Schymanski EL, Baker NC, Williams AJ, Singh RR, Trezzi JP, Wilmes P, Kolber PL, Kruger R, Paczia N, Linster CL, Balling R.

Environ Sci Process Impacts. 2019 Jul 15. doi: 10.1039/c9em00068b. [Epub ahead of print]


Mutations in RHOT1 disrupt ER-mitochondria contact sites interfering with calcium homeostasis and mitochondrial dynamics in Parkinson's disease.

Grossmann D, Berenguer-Escuder C, Bellet ME, Scheibner D, Bohler J, Massart F, Rapaport D, Skupin A, Fouquier d'Hérouël A, Sharma M, Ghelfi J, Rakovic A, Lichtner P, Antony P, Glaab E, May P, Dimmer KS, Fitzgerald JC, Gruenewald A, Krüger R.

Antioxid Redox Signal. 2019 Jul 15. doi: 10.1089/ars.2018.7718. [Epub ahead of print]


High-Intensity Interval Training Decreases Resting Urinary Hypoxanthine Concentration in Young Active Men-A Metabolomic Approach.

Kistner S, Rist MJ, Krüger R, Döring M, Schlechtweg S, Bub A.

Metabolites. 2019 Jul 10;9(7). pii: E137. doi: 10.3390/metabo9070137.


Phase I, Open-Label, Dose-Escalation Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of GSK2879552 in Relapsed/Refractory Small Cell Lung Cancer.

Bauer TM, Besse B, Martinez-Marti A, Trigo JM, Moreno V, Garrido P, Ferron-Brady G, Wu Y, Park J, Collingwood T, Kruger RG, Mohammad HP, Ballas MS, Dhar A, Govindan R.

J Thorac Oncol. 2019 Jun 28. pii: S1556-0864(19)30503-9. doi: 10.1016/j.jtho.2019.06.021. [Epub ahead of print]


Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss.

Fedoriw A, Rajapurkar SR, O'Brien S, Gerhart SV, Mitchell LH, Adams ND, Rioux N, Lingaraj T, Ribich SA, Pappalardi MB, Shah N, Laraio J, Liu Y, Butticello M, Carpenter CL, Creasy C, Korenchuk S, McCabe MT, McHugh CF, Nagarajan R, Wagner C, Zappacosta F, Annan R, Concha NO, Thomas RA, Hart TK, Smith JJ, Copeland RA, Moyer MP, Campbell J, Stickland K, Mills J, Jacques-O'Hagan S, Allain C, Johnston D, Raimondi A, Porter Scott M, Waters N, Swinger K, Boriack-Sjodin A, Riera T, Shapiro G, Chesworth R, Prinjha RK, Kruger RG, Barbash O, Mohammad HP.

Cancer Cell. 2019 Jul 8;36(1):100-114.e25. doi: 10.1016/j.ccell.2019.05.014. Epub 2019 Jun 27.


α-Synuclein in Parkinson's disease: causal or bystander?

Riederer P, Berg D, Casadei N, Cheng F, Classen J, Dresel C, Jost W, Krüger R, Müller T, Reichmann H, Rieß O, Storch A, Strobel S, van Eimeren T, Völker HU, Winkler J, Winklhofer KF, Wüllner U, Zunke F, Monoranu CM.

J Neural Transm (Vienna). 2019 Jul;126(7):815-840. doi: 10.1007/s00702-019-02025-9. Epub 2019 Jun 25. Review.


Mild hydrothermal pretreatment of sugarcane bagasse enhances the production of holocellulases by Aspergillus niger.

de Oliveira Gorgulho Silva C, de Castro Moreira Dos Santos Júnior A, Santana RH, Krüger RH, Fontes W, de Sousa MV, Ricart CAO, Filho EXF.

J Ind Microbiol Biotechnol. 2019 Jun 24. doi: 10.1007/s10295-019-02207-0. [Epub ahead of print]


Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.

Bell CC, Fennell KA, Chan YC, Rambow F, Yeung MM, Vassiliadis D, Lara L, Yeh P, Martelotto LG, Rogiers A, Kremer BE, Barbash O, Mohammad HP, Johanson TM, Burr ML, Dhar A, Karpinich N, Tian L, Tyler DS, MacPherson L, Shi J, Pinnawala N, Yew Fong C, Papenfuss AT, Grimmond SM, Dawson SJ, Allan RS, Kruger RG, Vakoc CR, Goode DL, Naik SH, Gilan O, Lam EYN, Marine JC, Prinjha RK, Dawson MA.

Nat Commun. 2019 Jun 20;10(1):2723. doi: 10.1038/s41467-019-10652-9.


Appreciating What's Unique about Every Stem Cell.

Kruger RP.

Cell. 2019 Jun 13;177(7):1663-1665. doi: 10.1016/j.cell.2019.05.037. No abstract available.


Molecular and serological surveys of canine distemper virus: A meta-analysis of cross-sectional studies.

Costa VGD, Saivish MV, Rodrigues RL, Lima Silva RF, Moreli ML, Krüger RH.

PLoS One. 2019 May 29;14(5):e0217594. doi: 10.1371/journal.pone.0217594. eCollection 2019.


Screening and treatment for tuberculosis in a cohort of unaccompanied minor refugees in Berlin, Germany.

Thee S, Krüger R, von Bernuth H, Meisel C, Kölsch U, Kirchberger V, Feiterna-Sperling C.

PLoS One. 2019 May 21;14(5):e0216234. doi: 10.1371/journal.pone.0216234. eCollection 2019.


Ethnic-specific suggestions for physical activity based on existing recreational physical activity preferences of New Zealand women.

O'Brien WJ, Shultz SP, Firestone RT, George L, Kruger R.

Aust N Z J Public Health. 2019 May 15. doi: 10.1111/1753-6405.12902. [Epub ahead of print]


Cycling Performed on an Innovative Ergometer at Different Intensities-Durations in Men: Neuromuscular Fatigue and Recovery Kinetics.

Krüger RL, Aboodarda SJ, Jaimes LM, Samozino P, Millet GY.

Appl Physiol Nutr Metab. 2019 May 13. doi: 10.1139/apnm-2018-0858. [Epub ahead of print]


Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.

Duy C, Teater M, Garrett-Bakelman FE, Lee TC, Meydan C, Glass JL, Li M, Hellmuth JC, Mohammad HP, Smitheman KN, Shih AH, Abdel-Wahab O, Tallman MS, Guzman ML, Muench D, Grimes HL, Roboz GJ, Kruger RG, Creasy CL, Paietta EM, Levine RL, Carroll M, Melnick AM.

Cancer Discov. 2019 Jul;9(7):872-889. doi: 10.1158/2159-8290.CD-19-0106. Epub 2019 May 10.


Environmental factors influence the Haloferax volcanii S-layer protein structure.

Rodrigues-Oliveira T, Souza AA, Kruger R, Schuster B, Maria de Freitas S, Kyaw CM.

PLoS One. 2019 May 10;14(5):e0216863. doi: 10.1371/journal.pone.0216863. eCollection 2019.


Phylogenetic diversity of aerobic spore-forming Bacillalles isolated from Brazilian soils.

Orem JC, Silva WMC, Raiol T, Magalhães MI, Martins PH, Cavalcante DA, Kruger RH, Brigido MM, De-Souza MT.

Int Microbiol. 2019 May 2. doi: 10.1007/s10123-019-00080-6. [Epub ahead of print]


Urinary Metabolites and Their Link with Premature Arterial Stiffness in Black Boys: The ASOS Study.

Erasmus D, Mels CMC, Louw R, Lindeque JZ, Kruger R.

Pulse (Basel). 2019 Apr;6(3-4):144-153. doi: 10.1159/000492155. Epub 2018 Aug 17.


May Measurement Month 2017: an analysis of blood pressure screening results in South Africa-Sub-Saharan Africa.

Woodiwiss AJ, Kruger R, Norton GR, Schutte AE, Vally M, Da Silva Fernandes D, Masiu M, Kolkenbeck-Ruh A, Gafane-Matemane LF, Ahiante BO, Phalane E, Crouch SH, Beaney T, Xia X, Poulter NR.

Eur Heart J Suppl. 2019 Apr;21(Suppl D):D104-D106. doi: 10.1093/eurheartj/suz069. Epub 2019 Apr 24.


May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension.

Beaney T, Burrell LM, Castillo RR, Charchar FJ, Cro S, Damasceno A, Kruger R, Nilsson PM, Prabhakaran D, Ramirez AJ, Schlaich MP, Schutte AE, Tomaszewski M, Touyz R, Wang JG, Weber MA, Poulter NR; MMM Investigators .

Eur Heart J. 2019 Jul 1;40(25):2006-2017. doi: 10.1093/eurheartj/ehz300.


Metagenomic Analysis of the Whole Gut Microbiota in Brazilian Termitidae Termites Cornitermes cumulans, Cyrilliotermes strictinasus, Syntermes dirus, Nasutitermes jaraguae, Nasutitermes aquilinus, Grigiotermes bequaerti, and Orthognathotermes mirim.

Grieco MB, Lopes FAC, Oliveira LS, Tschoeke DA, Popov CC, Thompson CC, Gonçalves LC, Constantino R, Martins OB, Kruger RH, de Souza W, Thompson FL.

Curr Microbiol. 2019 Jun;76(6):687-697. doi: 10.1007/s00284-019-01662-3. Epub 2019 Apr 5.


Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder.

Gerlach M, Sharma M, Romanos M, Lesch KP, Walitza S, Conzelmann HA, Krüger R, Renner TJ.

Atten Defic Hyperact Disord. 2019 Mar;11(1):107-111. doi: 10.1007/s12402-019-00286-8. Epub 2019 Mar 29.


Fatigue and recovery measured with dynamic properties versus isometric force: effects of exercise intensity.

Krüger RL, Aboodarda SJ, Jaimes LM, MacIntosh BR, Samozino P, Millet GY.

J Exp Biol. 2019 May 9;222(Pt 9). pii: jeb197483. doi: 10.1242/jeb.197483.


Adherence to daily dietary and activity goals set within a Māori and Pacific weight loss competition.

Glover M, Nolte M, Wagemakers A, McRobbie H, Kruger R, Breier BH, Stephen J, Funaki-Tahifote M, Shanthakumar M.

BMC Obes. 2019 Mar 4;6:6. doi: 10.1186/s40608-019-0228-6. eCollection 2019.


Long-Term Effects of Periodical Fires on Archaeal Communities from Brazilian Cerrado Soils.

Belmok A, Rodrigues-Oliveira T, Lopes FAC, Miranda HS, Krüger RH, Kyaw CM.

Archaea. 2019 Jan 27;2019:6957210. doi: 10.1155/2019/6957210. eCollection 2019.


7-Chloro-4-(Phenylselanyl) Quinoline with Memory Enhancer Action in Aging Rats: Modulation of Neuroplasticity, Acetylcholinesterase Activity, and Cholesterol Levels.

Barth A, Vogt AG, Dos Reis AS, Pinz MP, Krüger R, Domingues WB, Alves D, Campos VF, Pinton S, Paroul N, Wilhelm EA, Luchese C.

Mol Neurobiol. 2019 Feb 25. doi: 10.1007/s12035-019-1530-5. [Epub ahead of print]


Development of an Interprofessional Educational Electronic Health Record.

Rees G, Morrison J, Ahuja K, Anthony J, Blanes N, Borycki EM, Bower L, Isaak C, Kruger R, Kushniruk A, Min J, Moore C, Visosky P, Currie L.

Stud Health Technol Inform. 2019;257:364-369.


Anodal tDCS modulates cortical activity and synchronization in Parkinson's disease depending on motor processing.

Schoellmann A, Scholten M, Wasserka B, Govindan RB, Krüger R, Gharabaghi A, Plewnia C, Weiss D.

Neuroimage Clin. 2019;22:101689. doi: 10.1016/j.nicl.2019.101689. Epub 2019 Jan 23.


The African Prospective study on the Early Detection and Identification of Cardiovascular disease and Hypertension (African-PREDICT): Design, recruitment and initial examination.

Schutte AE, Gona PN, Delles C, Uys AS, Burger A, Mels CM, Kruger R, Smith W, Fourie CM, Botha S, Lammertyn L, van Rooyen JM, Gafane-Matemane LF, Mokwatsi GG, Breet Y, Kruger HS, Zyl TV, Pieters M, Zandberg L, Louw R, Moss SJ, Khumalo IP, Huisman HW.

Eur J Prev Cardiol. 2019 Mar;26(5):458-470. doi: 10.1177/2047487318822354. Epub 2019 Jan 6.


CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis.

Greenblatt SM, Man N, Hamard PJ, Asai T, Karl D, Martinez C, Bilbao D, Stathias V, Jermakowicz AM, Duffort S, Tadi M, Blumenthal E, Newman S, Vu L, Xu Y, Liu F, Schurer SC, McCabe MT, Kruger RG, Xu M, Yang FC, Tenen DG, Watts J, Vega F, Nimer SD.

Cancer Cell. 2019 Jan 14;35(1):156. doi: 10.1016/j.ccell.2018.12.008. No abstract available.


Assessing tobacco use in an African population: Serum and urine cotinine cut-offs from South Africa.

Ware LJ, Charlton K, Kruger R, Breet Y, van Rooyen J, Huisman H, Botha S, Uys AS, Rennie KL, Naidoo N, Kowal P, Schutte AE.

Drug Alcohol Depend. 2019 Feb 1;195:82-89. doi: 10.1016/j.drugalcdep.2018.11.022. Epub 2018 Dec 21.


Management of Parkinson's Disease 20 Years from Now: Towards Digital Health Pathways.

Klucken J, Krüger R, Schmidt P, Bloem BR.

J Parkinsons Dis. 2018;8(s1):S85-S94. doi: 10.3233/JPD-181519.


Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity.

Fehlmann T, Laufer T, Backes C, Kahramann M, Alles J, Fischer U, Minet M, Ludwig N, Kern F, Kehl T, Galata V, Düsterloh A, Schrörs H, Kohlhaas J, Bals R, Huwer H, Geffers L, Krüger R, Balling R, Lenhof HP, Meese E, Keller A.

RNA Biol. 2019 Jan;16(1):93-103. doi: 10.1080/15476286.2018.1559689. Epub 2018 Dec 26.


Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis.

Hatzi K, Geng H, Doane AS, Meydan C, LaRiviere R, Cardenas M, Duy C, Shen H, Vidal MNC, Baslan T, Mohammad HP, Kruger RG, Shaknovich R, Haberman AM, Inghirami G, Lowe SW, Melnick AM.

Nat Immunol. 2019 Jan;20(1):86-96. doi: 10.1038/s41590-018-0273-1. Epub 2018 Dec 10.


Left ventricular mass independently associates with 24-hour sodium excretion in young masked hypertensive adults: The African-PREDICT study.

van der Westhuizen B, Schutte AE, Gafane-Matemane LF, Kruger R.

Int J Cardiol. 2019 Feb 1;276:218-223. doi: 10.1016/j.ijcard.2018.11.116. Epub 2018 Nov 24.


Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes.

Smitheman KN, Severson TM, Rajapurkar SR, McCabe MT, Karpinich N, Foley J, Pappalardi MB, Hughes A, Halsey W, Thomas E, Traini C, Federowicz KE, Laraio J, Mobegi F, Ferron-Brady G, Prinjha RK, Carpenter CL, Kruger RG, Wessels L, Mohammad HP.

Haematologica. 2019 Jun;104(6):1156-1167. doi: 10.3324/haematol.2018.199190. Epub 2018 Dec 4.


Understanding the role of genetic variability in LRRK2 in Indian population.

Kishore A, Ashok Kumar Sreelatha A, Sturm M, von-Zweydorf F, Pihlstrøm L, Raimondi F, Russell R, Lichtner P, Banerjee M, Krishnan S, Rajan R, Puthenveedu DK, Chung SJ; International Parkinson's Disease Genomics Consortium (IPDGC); Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson's Disease (COURAGE-PD), Bauer P, Riess O, Gloeckner CJ, Kruger R, Gasser T, Sharma M.

Mov Disord. 2019 Apr;34(4):496-505. doi: 10.1002/mds.27558. Epub 2018 Nov 28.


Correction: Morning blood pressure surge in young black and white adults: The African-PREDICT Study.

Mokwatsi GG, Schutte AE, Mels CMC, Kruger R.

J Hum Hypertens. 2019 Feb;33(2):172. doi: 10.1038/s41371-018-0121-7.


From Cellular Diversity to the Roots of Variability.

Kruger RP.

Cell. 2018 Nov 15;175(5):1169-1171. doi: 10.1016/j.cell.2018.11.001. No abstract available.


An unusual pelvic mass: Contrast-enhanced sonographic diagnosis of pelvic splenosis.

Kruger R, Freeman S.

J Clin Ultrasound. 2019 Mar;47(3):172-174. doi: 10.1002/jcu.22671. Epub 2018 Nov 16.


CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis.

Greenblatt SM, Man N, Hamard PJ, Asai T, Karl D, Martinez C, Bilbao D, Stathias V, McGrew-Jermacowicz A, Duffort S, Tadi M, Blumenthal E, Newman S, Vu L, Xu Y, Liu F, Schurer SC, McCabe MT, Kruger RG, Xu M, Yang FC, Tenen D, Watts J, Vega F, Nimer SD.

Cancer Cell. 2018 Nov 12;34(5):868. doi: 10.1016/j.ccell.2018.10.009. No abstract available.


The Luxembourg Parkinson's Study: A Comprehensive Approach for Stratification and Early Diagnosis.

Hipp G, Vaillant M, Diederich NJ, Roomp K, Satagopam VP, Banda P, Sandt E, Mommaerts K, Schmitz SK, Longhino L, Schweicher A, Hanff AM, Nicolai B, Kolber P, Reiter D, Pavelka L, Binck S, Pauly C, Geffers L, Betsou F, Gantenbein M, Klucken J, Gasser T, Hu MT, Balling R, Krüger R.

Front Aging Neurosci. 2018 Oct 29;10:326. doi: 10.3389/fnagi.2018.00326. eCollection 2018.


Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3.

Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J.

Front Mol Neurosci. 2018 Oct 10;11:368. doi: 10.3389/fnmol.2018.00368. eCollection 2018.


Metagenomics of Coral Reefs Under Phase Shift and High Hydrodynamics.

Meirelles PM, Soares AC, Oliveira L, Leomil L, Appolinario LR, Francini-Filho RB, de Moura RL, de Barros Almeida RT, Salomon PS, Amado-Filho GM, Kruger R, Siegle E, Tschoeke DA, Kudo I, Mino S, Sawabe T, Thompson CC, Thompson FL.

Front Microbiol. 2018 Oct 4;9:2203. doi: 10.3389/fmicb.2018.02203. eCollection 2018.


Development and evaluation of a food frequency questionnaire to assess nutrient intakes of adult women in New Zealand.

Beck KL, Houston ZL, McNaughton SA, Kruger R.

Nutr Diet. 2018 Sep 14. doi: 10.1111/1747-0080.12472. [Epub ahead of print]


Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.

Sollberger G, Choidas A, Burn GL, Habenberger P, Di Lucrezia R, Kordes S, Menninger S, Eickhoff J, Nussbaumer P, Klebl B, Krüger R, Herzig A, Zychlinsky A.

Sci Immunol. 2018 Aug 24;3(26). pii: eaar6689. doi: 10.1126/sciimmunol.aar6689.


Morning Blood Pressure Surge Relates to Autonomic Neural Activity in Young Non-Dipping Adults: The African-PREDICT Study.

Mokwatsi GG, Schutte AE, Mels CMC, Kruger R.

Heart Lung Circ. 2019 Aug;28(8):1197-1205. doi: 10.1016/j.hlc.2018.07.003. Epub 2018 Jul 30.


Periorbital infections and conjunctivitis due to Panton-Valentine Leukocidin (PVL) positive Staphylococcus aureus in children.

Hoppe PA, Hanitsch LG, Leistner R, Niebank M, Bührer C, von Bernuth H, Krüger R.

BMC Infect Dis. 2018 Aug 6;18(1):371. doi: 10.1186/s12879-018-3281-8.


Correction to: Large artery stiffness is associated with salt intake in young healthy black but not white adults: the African-PREDICT study.

Strauss M, Smith W, Kruger R, van der Westhuizen B, Schutte AE.

Eur J Nutr. 2018 Oct;57(7):2657. doi: 10.1007/s00394-018-1800-4.


Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons.

Bolze A, Boisson B, Bosch B, Antipenko A, Bouaziz M, Sackstein P, Chaker-Margot M, Barlogis V, Briggs T, Colino E, Elmore AC, Fischer A, Genel F, Hewlett A, Jedidi M, Kelecic J, Krüger R, Ku CL, Kumararatne D, Lefevre-Utile A, Loughlin S, Mahlaoui N, Markus S, Garcia JM, Nizon M, Oleastro M, Pac M, Picard C, Pollard AJ, Rodriguez-Gallego C, Thomas C, Von Bernuth H, Worth A, Meyts I, Risolino M, Selleri L, Puel A, Klinge S, Abel L, Casanova JL.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8007-E8016. doi: 10.1073/pnas.1805437115. Epub 2018 Aug 2.

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