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Items: 1 to 50 of 73

1.

T2 Mapping as a New Method for Quantitative Assessment of Cartilage Damage in RA.

Renner N, Kleyer A, Krönke G, Simon D, Söllner S, Rech J, Uder M, Janka R, Schett G, Welsch GH, Pachowsky ML.

J Rheumatol. 2019 Aug 15. pii: jrheum.180728. doi: 10.3899/jrheum.180728. [Epub ahead of print]

PMID:
31416926
2.

Locally renewing resident synovial macrophages provide a protective barrier for the joint.

Culemann S, Grüneboom A, Nicolás-Ávila JÁ, Weidner D, Lämmle KF, Rothe T, Quintana JA, Kirchner P, Krljanac B, Eberhardt M, Ferrazzi F, Kretzschmar E, Schicht M, Fischer K, Gelse K, Faas M, Pfeifle R, Ackermann JA, Pachowsky M, Renner N, Simon D, Haseloff RF, Ekici AB, Bäuerle T, Blasig IE, Vera J, Voehringer D, Kleyer A, Paulsen F, Schett G, Hidalgo A, Krönke G.

Nature. 2019 Aug;572(7771):670-675. doi: 10.1038/s41586-019-1471-1. Epub 2019 Aug 7.

PMID:
31391580
3.

RELMα-expressing macrophages protect against fatal lung damage and reduce parasite burden during helminth infection.

Krljanac B, Schubart C, Naumann R, Wirtz S, Culemann S, Krönke G, Voehringer D.

Sci Immunol. 2019 May 24;4(35). pii: eaau3814. doi: 10.1126/sciimmunol.aau3814.

PMID:
31126996
4.

Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity.

Allen-Redpath K, Aldrovandi M, Lauder SN, Gketsopoulou A, Tyrrell VJ, Slatter DA, Andrews R, Watkins WJ, Atkinson G, McNeill E, Gilfedder A, Protty M, Burston J, Johnson SRC, Rodrigues PRS, Jones DO, Lee R, Handa A, Channon K, Obaji S, Alvarez-Jarreta J, Krönke G, Ackermann J, Jenkins PV, Collins PW, O'Donnell VB.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):8038-8047. doi: 10.1073/pnas.1814409116. Epub 2019 Apr 3.

5.

Enzymatically oxidized phospholipids assume center stage as essential regulators of innate immunity and cell death.

O'Donnell VB, Aldrovandi M, Murphy RC, Krönke G.

Sci Signal. 2019 Mar 26;12(574). pii: eaau2293. doi: 10.1126/scisignal.aau2293. Review.

PMID:
30914483
6.

Modular Lattice Constructs for Biological Joint Resurfacing.

Gelse K, Biggemann J, Stumpf M, Halmheu M, Grüneboom A, Kleyer A, Scholtysek C, Pachowsky ML, Hueber A, Krönke G, Fey T.

Tissue Eng Part A. 2019 Jul;25(13-14):1053-1062. doi: 10.1089/ten.TEA.2018.0231. Epub 2019 Mar 18.

PMID:
30638150
7.

Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis.

Koenen M, Culemann S, Vettorazzi S, Caratti G, Frappart L, Baum W, Krönke G, Baschant U, Tuckermann JP.

Ann Rheum Dis. 2018 Nov;77(11):1610-1618. doi: 10.1136/annrheumdis-2017-212762. Epub 2018 Jul 11.

8.

The involvement of Toll-like receptor 9 in the pathogenesis of erosive autoimmune arthritis.

Fischer A, Abdollahi-Roodsaz S, Böhm C, Niederreiter B, Meyer B, Yau ACY, Lönnblom E, Joosten LAB, Koenders M, Lehmann CHK, Dudziak D, Krönke G, Holmdahl R, Steiner G.

J Cell Mol Med. 2018 Sep;22(9):4399-4409. doi: 10.1111/jcmm.13735. Epub 2018 Jul 11.

9.

Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice.

Omata Y, Frech M, Primbs T, Lucas S, Andreev D, Scholtysek C, Sarter K, Kindermann M, Yeremenko N, Baeten DL, Andreas N, Kamradt T, Bozec A, Ramming A, Krönke G, Wirtz S, Schett G, Zaiss MM.

Cell Rep. 2018 Jul 3;24(1):169-180. doi: 10.1016/j.celrep.2018.06.005.

10.

NR4A1 Regulates Motility of Osteoclast Precursors and Serves as Target for the Modulation of Systemic Bone Turnover.

Scholtysek C, Ipseiz N, Böhm C, Krishnacoumar B, Stenzel M, Czerwinski T, Palumbo-Zerr K, Rothe T, Weidner D, Klej A, Stoll C, Distler J, Tuckermann J, Herrmann M, Fabry B, Goldmann WH, Schett G, Krönke G.

J Bone Miner Res. 2018 Nov;33(11):2035-2047. doi: 10.1002/jbmr.3533. Epub 2018 Jul 24.

PMID:
29949664
11.

Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus.

Biermann MHC, Boeltz S, Pieterse E, Knopf J, Rech J, Bilyy R, van der Vlag J, Tincani A, Distler JHW, Krönke G, Schett GA, Herrmann M, Muñoz LE.

Front Immunol. 2018 May 7;9:989. doi: 10.3389/fimmu.2018.00989. eCollection 2018.

12.

Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women.

Engdahl C, Bondt A, Harre U, Raufer J, Pfeifle R, Camponeschi A, Wuhrer M, Seeling M, Mårtensson IL, Nimmerjahn F, Krönke G, Scherer HU, Forsblad-d'Elia H, Schett G.

Arthritis Res Ther. 2018 May 2;20(1):84. doi: 10.1186/s13075-018-1586-z.

13.

[Osteoimmunology-IMMUNOBONE : Regulation of bone by inflammation].

Rauner M, Buttgereit F, Distler J, Garbe AI, Herrmann M, Hofbauer L, Hoffmann M, Jessberger R, Kornak U, Krönke G, Mundlos S, Spies C, Tuckermann J, Zwerina J.

Z Rheumatol. 2018 May;77(Suppl 1):12-15. doi: 10.1007/s00393-018-0455-0. Review. German. No abstract available.

PMID:
29691689
14.

[Mutual influence of immune system and bones].

Kamradt T, Amling M, Dankbar B, Dudeck A, Gunzer M, Ignatius A, Krönke G, Kubatzky K, Pap T, Prinz I, Schett G, Schinke T, Tuckermann J, Waisman A.

Z Rheumatol. 2018 May;77(Suppl 1):8-11. doi: 10.1007/s00393-018-0454-1. Review. German. No abstract available.

PMID:
29675686
15.

Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

Uderhardt S, Ackermann JA, Fillep T, Hammond VJ, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner KR, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz-Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins PW, Schabbauer G, Mackman N, Voehringer D, Nadler JL, Lee JJ, Massberg S, Rauh M, Kiechl S, Schett G, O'Donnell VB, Krönke G.

J Exp Med. 2018 Mar 5;215(3):1003. doi: 10.1084/jem.2016107002142018c. Epub 2018 Feb 20. No abstract available.

16.

Eosinophils are not essential for maintenance of murine plasma cells in the bone marrow.

Haberland K, Ackermann JA, Ipseiz N, Culemann S, Pracht K, Englbrecht M, Jäck HM, Schett G, Schuh W, Krönke G.

Eur J Immunol. 2018 May;48(5):822-828. doi: 10.1002/eji.201747227. Epub 2018 Mar 5.

17.

The B cell response to citrullinated antigens in the development of rheumatoid arthritis.

Scherer HU, Huizinga TWJ, Krönke G, Schett G, Toes REM.

Nat Rev Rheumatol. 2018 Mar;14(3):157-169. doi: 10.1038/nrrheum.2018.10. Epub 2018 Feb 8. Review.

PMID:
29416134
18.

Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss.

Lucas S, Omata Y, Hofmann J, Böttcher M, Iljazovic A, Sarter K, Albrecht O, Schulz O, Krishnacoumar B, Krönke G, Herrmann M, Mougiakakos D, Strowig T, Schett G, Zaiss MM.

Nat Commun. 2018 Jan 4;9(1):55. doi: 10.1038/s41467-017-02490-4.

19.

Runx2 mediated Induction of Novel Targets ST2 and Runx3 Leads to Cooperative Regulation of Hypertrophic Differentiation in ATDC5 Chondrocytes.

Bonyadi Rad E, Musumeci G, Pichler K, Heidary M, Szychlinska MA, Castrogiovanni P, Marth E, Böhm C, Srinivasaiah S, Krönke G, Weinberg A, Schäfer U.

Sci Rep. 2017 Dec 20;7(1):17947. doi: 10.1038/s41598-017-18044-z.

20.

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

Lauder SN, Allen-Redpath K, Slatter DA, Aldrovandi M, O'Connor A, Farewell D, Percy CL, Molhoek JE, Rannikko S, Tyrrell VJ, Ferla S, Milne GL, Poole AW, Thomas CP, Obaji S, Taylor PR, Jones SA, de Groot PG, Urbanus RT, Hörkkö S, Uderhardt S, Ackermann J, Vince Jenkins P, Brancale A, Krönke G, Collins PW, O'Donnell VB.

Sci Signal. 2017 Nov 28;10(507). pii: eaan2787. doi: 10.1126/scisignal.aan2787.

21.

Full Length Interleukin 33 Aggravates Radiation-Induced Skin Reaction.

Kurow O, Frey B, Schuster L, Schmitt V, Adam S, Hahn M, Gilchrist D, McInnes IB, Wirtz S, Gaipl US, Krönke G, Schett G, Frey S, Hueber AJ.

Front Immunol. 2017 Jun 28;8:722. doi: 10.3389/fimmu.2017.00722. eCollection 2017.

22.

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

Uderhardt S, Ackermann JA, Fillep T, Hammond VJ, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner KR, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz-Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins PW, Schabbauer G, Mackman N, Voehringer D, Nadler JL, Lee JJ, Massberg S, Rauh M, Kiechl S, Schett G, O'Donnell VB, Krönke G.

J Exp Med. 2017 Jul 3;214(7):2121-2138. doi: 10.1084/jem.20161070. Epub 2017 May 31. Erratum in: J Exp Med. 2018 Feb 20;:.

23.

The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation.

Rothe T, Ipseiz N, Faas M, Lang S, Perez-Branguli F, Metzger D, Ichinose H, Winner B, Schett G, Krönke G.

J Immunol. 2017 May 15;198(10):3878-3885. doi: 10.4049/jimmunol.1600638. Epub 2017 Apr 14.

24.

Development of three-dimensional prints of arthritic joints for supporting patients' awareness to structural damage.

Kleyer A, Beyer L, Simon C, Stemmler F, Englbrecht M, Beyer C, Rech J, Manger B, Krönke G, Schett G, Hueber AJ.

Arthritis Res Ther. 2017 Feb 10;19(1):34. doi: 10.1186/s13075-017-1234-z.

25.

PPARβ/δ: A master regulator of mesenchymal stem cell functions.

Djouad F, Ipseiz N, Luz-Crawford P, Scholtysek C, Krönke G, Jorgensen C.

Biochimie. 2017 May;136:55-58. doi: 10.1016/j.biochi.2016.11.011. Epub 2016 Nov 30. Review.

PMID:
27914902
26.

Corrigendum to "Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis" [Osteoarthritis Cartilage 23 (2015) 1221-1225].

Stock M, Distler A, Distler J, Beyer C, Ruiz-Heiland G, Ipseiz N, Seeling M, Krönke G, Nimmerjahn F, Schett G.

Osteoarthritis Cartilage. 2017 Jun;25(6):995. doi: 10.1016/j.joca.2016.11.003. Epub 2016 Nov 17. No abstract available.

27.

Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.

Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G.

Nat Immunol. 2017 Jan;18(1):104-113. doi: 10.1038/ni.3579. Epub 2016 Nov 7.

28.

The double-edged role of 12/15-lipoxygenase during inflammation and immunity.

Ackermann JA, Hofheinz K, Zaiss MM, Krönke G.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Apr;1862(4):371-381. doi: 10.1016/j.bbalip.2016.07.014. Epub 2016 Jul 30. Review.

PMID:
27480217
29.

PPARβ/δ directs the therapeutic potential of mesenchymal stem cells in arthritis.

Luz-Crawford P, Ipseiz N, Espinosa-Carrasco G, Caicedo A, Tejedor G, Toupet K, Loriau J, Scholtysek C, Stoll C, Khoury M, Noël D, Jorgensen C, Krönke G, Djouad F.

Ann Rheum Dis. 2016 Dec;75(12):2166-2174. doi: 10.1136/annrheumdis-2015-208696. Epub 2016 Mar 8.

PMID:
26964143
30.

Microbiota from Obese Mice Regulate Hematopoietic Stem Cell Differentiation by Altering the Bone Niche.

Luo Y, Chen GL, Hannemann N, Ipseiz N, Krönke G, Bäuerle T, Munos L, Wirtz S, Schett G, Bozec A.

Cell Metab. 2015 Nov 3;22(5):886-94. doi: 10.1016/j.cmet.2015.08.020. Epub 2015 Sep 17.

31.

A role for 12/15-lipoxygenase-derived proresolving mediators in postoperative ileus: protectin DX-regulated neutrophil extravasation.

Stein K, Stoffels M, Lysson M, Schneiker B, Dewald O, Krönke G, Kalff JC, Wehner S.

J Leukoc Biol. 2016 Feb;99(2):231-9. doi: 10.1189/jlb.3HI0515-189R. Epub 2015 Aug 20.

PMID:
26292977
32.

Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis.

Sahin E, Brunner JS, Kral JB, Kuttke M, Hanzl L, Datler H, Paar H, Neuwinger N, Saferding V, Zinser E, Halfmann A, Soukup K, Hainzl E, Lohmeyer T, Niederreiter B, Haider T, Dohnal AM, Krönke G, Blüml S, Schabbauer G.

J Immunol. 2015 Sep 15;195(6):2560-70. doi: 10.4049/jimmunol.1402511. Epub 2015 Aug 5.

33.

12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function.

Rothe T, Gruber F, Uderhardt S, Ipseiz N, Rössner S, Oskolkova O, Blüml S, Leitinger N, Bicker W, Bochkov VN, Yamamoto M, Steinkasserer A, Schett G, Zinser E, Krönke G.

J Clin Invest. 2015 May;125(5):1944-54. doi: 10.1172/JCI78490. Epub 2015 Apr 6.

34.

Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss.

Harre U, Lang SC, Pfeifle R, Rombouts Y, Frühbeißer S, Amara K, Bang H, Lux A, Koeleman CA, Baum W, Dietel K, Gröhn F, Malmström V, Klareskog L, Krönke G, Kocijan R, Nimmerjahn F, Toes RE, Herrmann M, Scherer HU, Schett G.

Nat Commun. 2015 Mar 31;6:6651. doi: 10.1038/ncomms7651.

35.

Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis.

Stock M, Distler A, Distler J, Beyer C, Ruiz-Heiland G, Ipseiz N, Seeling M, Krönke G, Nimmerjahn F, Schett G.

Osteoarthritis Cartilage. 2015 Jul;23(7):1221-5. doi: 10.1016/j.joca.2015.02.019. Epub 2015 Mar 4. Erratum in: Osteoarthritis Cartilage. 2017 Jun;25(6):995.

36.

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis.

Palumbo-Zerr K, Zerr P, Distler A, Fliehr J, Mancuso R, Huang J, Mielenz D, Tomcik M, Fürnrohr BG, Scholtysek C, Dees C, Beyer C, Krönke G, Metzger D, Distler O, Schett G, Distler JH.

Nat Med. 2015 Feb;21(2):150-8. doi: 10.1038/nm.3777. Epub 2015 Jan 12.

PMID:
25581517
37.

Adopted orphans as regulators of inflammation, immunity and skeletal homeostasis.

Ipseiz N, Scholtysek C, Culemann S, Krönke G.

Swiss Med Wkly. 2014 Dec 4;144:w14055. doi: 10.4414/smw.2014.14055. eCollection 2014. Review.

38.

Anti–citrullinated protein antibody positivity correlates with cartilage damage and proteoglycan levels in patients with rheumatoid arthritis in the hand joints.

Renner N, Krönke G, Rech J, Uder M, Janka R, Lauer L, Paul D, Herz B, Schlechtweg P, Hennig FF, Schett G, Welsch G.

Arthritis Rheumatol. 2014 Dec;66(12):3283-8.

39.

Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.

Kelkka T, Kienhöfer D, Hoffmann M, Linja M, Wing K, Sareila O, Hultqvist M, Laajala E, Chen Z, Vasconcelos J, Neves E, Guedes M, Marques L, Krönke G, Helminen M, Kainulainen L, Olofsson P, Jalkanen S, Lahesmaa R, Souto-Carneiro MM, Holmdahl R.

Antioxid Redox Signal. 2014 Dec 1;21(16):2231-45. doi: 10.1089/ars.2013.5828. Epub 2014 Jul 29.

40.

The nuclear receptor Nr4a1 mediates anti-inflammatory effects of apoptotic cells.

Ipseiz N, Uderhardt S, Scholtysek C, Steffen M, Schabbauer G, Bozec A, Schett G, Krönke G.

J Immunol. 2014 May 15;192(10):4852-8. doi: 10.4049/jimmunol.1303377. Epub 2014 Apr 16.

41.

Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages.

Beyer C, Huang J, Beer J, Zhang Y, Palumbo-Zerr K, Zerr P, Distler A, Dees C, Maier C, Munoz L, Krönke G, Uderhardt S, Distler O, Jones S, Rose-John S, Oravecz T, Schett G, Distler JH.

Ann Rheum Dis. 2015 Jun;74(6):1317-24. doi: 10.1136/annrheumdis-2013-204401. Epub 2014 Mar 11.

PMID:
24618263
42.

Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids.

Lauber K, Keppeler H, Munoz LE, Koppe U, Schröder K, Yamaguchi H, Krönke G, Uderhardt S, Wesselborg S, Belka C, Nagata S, Herrmann M.

Cell Death Differ. 2013 Sep;20(9):1230-40. doi: 10.1038/cdd.2013.82. Epub 2013 Jul 5.

43.

PPARβ/δ governs Wnt signaling and bone turnover.

Scholtysek C, Katzenbeisser J, Fu H, Uderhardt S, Ipseiz N, Stoll C, Zaiss MM, Stock M, Donhauser L, Böhm C, Kleyer A, Hess A, Engelke K, David JP, Djouad F, Tuckermann JP, Desvergne B, Schett G, Krönke G.

Nat Med. 2013 May;19(5):608-13. doi: 10.1038/nm.3146. Epub 2013 Mar 31.

PMID:
23542786
44.

12/15-lipoxygenase during the regulation of inflammation, immunity, and self-tolerance.

Uderhardt S, Krönke G.

J Mol Med (Berl). 2012 Nov;90(11):1247-56. doi: 10.1007/s00109-012-0954-4. Epub 2012 Sep 15. Review.

PMID:
22983484
45.

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.

Lin NY, Beyer C, Giessl A, Kireva T, Scholtysek C, Uderhardt S, Munoz LE, Dees C, Distler A, Wirtz S, Krönke G, Spencer B, Distler O, Schett G, Distler JH.

Ann Rheum Dis. 2013 May;72(5):761-8. doi: 10.1136/annrheumdis-2012-201671. Epub 2012 Sep 12.

PMID:
22975756
46.

Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss.

Kleyer A, Scholtysek C, Bottesch E, Hillienhof U, Beyer C, Distler JH, Tuckermann JP, Schett G, Krönke G.

J Bone Miner Res. 2012 Dec;27(12):2442-51. doi: 10.1002/jbmr.1702.

47.

Development of myeloproliferative disease in 12/15-lipoxygenase deficiency.

Taylor PR, Heydeck D, Jones GW, Krönke G, Funk CD, Knapper S, Adams D, Kühn H, O'Donnell VB.

Blood. 2012 Jun 21;119(25):6173-4; author reply 6174-5. doi: 10.1182/blood-2012-02-410928. No abstract available.

48.

12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance.

Uderhardt S, Herrmann M, Oskolkova OV, Aschermann S, Bicker W, Ipseiz N, Sarter K, Frey B, Rothe T, Voll R, Nimmerjahn F, Bochkov VN, Schett G, Krönke G.

Immunity. 2012 May 25;36(5):834-46. doi: 10.1016/j.immuni.2012.03.010. Epub 2012 Apr 12.

49.

Inflammation-associated changes in bone homeostasis.

Scholtysek C, Krönke G, Schett G.

Inflamm Allergy Drug Targets. 2012 Jun;11(3):188-95. Review.

PMID:
22280240
50.

IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1.

Schwab I, Biburger M, Krönke G, Schett G, Nimmerjahn F.

Eur J Immunol. 2012 Apr;42(4):826-30. doi: 10.1002/eji.201142260.

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