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Items: 37

1.

Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse.

Perea-Gomez A, Cases O, Lelièvre V, Pulina MV, Collignon J, Hadjantonakis AK, Kozyraki R.

Sci Rep. 2019 Jul 15;9(1):10168. doi: 10.1038/s41598-019-46559-0.

2.

CORRELATIONS BETWEEN EXPERIMENTAL MYOPIA MODELS AND HUMAN PATHOLOGIC MYOPIA.

Vutipongsatorn K, Nagaoka N, Yokoi T, Yoshida T, Kamoi K, Horie S, Uramoto K, Hirata A, Occelli LM, Petersen-Jones SM, Montiani-Ferreira F, Cases O, Kozyraki R, Jonas JB, Ohno-Matsui K.

Retina. 2019 Apr;39(4):621-635. doi: 10.1097/IAE.0000000000002426.

PMID:
30586351
3.

Cubilin, the intrinsic factor-vitamin B12 receptor in development and disease.

Kozyraki R, Cases O.

Curr Med Chem. 2018 Oct 8. doi: 10.2174/0929867325666181008143945. [Epub ahead of print]

PMID:
30295181
4.

Preliminary study of the safety and efficacy of medium-chain triglycerides for use as an intraocular tamponading agent in minipigs.

Soler VJ, Laurent C, Sakr F, Regnier A, Tricoire C, Cases O, Kozyraki R, Douet JY, Pagot-Mathis V.

Graefes Arch Clin Exp Ophthalmol. 2017 Aug;255(8):1593-1604. doi: 10.1007/s00417-017-3695-9. Epub 2017 May 25.

PMID:
28547316
5.

FAM20A Gene Mutation: Amelogenesis or Ectopic Mineralization?

Lignon G, Beres F, Quentric M, Rouzière S, Weil R, De La Dure-Molla M, Naveau A, Kozyraki R, Dessombz A, Berdal A.

Front Physiol. 2017 May 3;8:267. doi: 10.3389/fphys.2017.00267. eCollection 2017.

6.

Impaired vitreous composition and retinal pigment epithelium function in the FoxG1::LRP2 myopic mice.

Cases O, Obry A, Ben-Yacoub S, Augustin S, Joseph A, Toutirais G, Simonutti M, Christ A, Cosette P, Kozyraki R.

Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1242-1254. doi: 10.1016/j.bbadis.2017.03.022. Epub 2017 Mar 31.

7.

Tubular proteinuria in patients with HNF1α mutations: HNF1α drives endocytosis in the proximal tubule.

Terryn S, Tanaka K, Lengelé JP, Olinger E, Dubois-Laforgue D, Garbay S, Kozyraki R, Van Der Smissen P, Christensen EI, Courtoy PJ, Bellanné-Chantelot C, Timsit J, Pontoglio M, Devuyst O.

Kidney Int. 2016 May;89(5):1075-1089. doi: 10.1016/j.kint.2016.01.027. Epub 2016 Mar 29.

PMID:
27083284
8.

Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia.

Cases O, Joseph A, Obry A, Santin MD, Ben-Yacoub S, Pâques M, Amsellem-Levera S, Bribian A, Simonutti M, Augustin S, Debeir T, Sahel JA, Christ A, de Castro F, Lehéricy S, Cosette P, Kozyraki R.

PLoS One. 2015 Jun 24;10(6):e0129518. doi: 10.1371/journal.pone.0129518. eCollection 2015.

9.

Detailed investigations of proximal tubular function in Imerslund-Gräsbeck syndrome.

Storm T, Zeitz C, Cases O, Amsellem S, Verroust PJ, Madsen M, Benoist JF, Passemard S, Lebon S, Jønsson IM, Emma F, Koldsø H, Hertz JM, Nielsen R, Christensen EI, Kozyraki R.

BMC Med Genet. 2013 Oct 24;14:111. doi: 10.1186/1471-2350-14-111.

10.

Cubilin, a high affinity receptor for fibroblast growth factor 8, is required for cell survival in the developing vertebrate head.

Cases O, Perea-Gomez A, Aguiar DP, Nykjaer A, Amsellem S, Chandellier J, Umbhauer M, Cereghini S, Madsen M, Collignon J, Verroust P, Riou JF, Creuzet SE, Kozyraki R.

J Biol Chem. 2013 Jun 7;288(23):16655-70. doi: 10.1074/jbc.M113.451070. Epub 2013 Apr 16.

11.

Vitamin B12 absorption: mammalian physiology and acquired and inherited disorders.

Kozyraki R, Cases O.

Biochimie. 2013 May;95(5):1002-7. doi: 10.1016/j.biochi.2012.11.004. Epub 2012 Nov 20. Review.

PMID:
23178706
12.

How can cobalamin injections be spaced in long-term therapy for inborn errors of vitamin B(12) absorption?

Boina Abdallah A, Ogier de Baulny H, Kozyraki R, Passemard S, Fenneteau O, Lebon S, Rigal O, Mesples B, Yacouben K, Giraudier S, Benoist JF, Schiff M.

Mol Genet Metab. 2012 Sep;107(1-2):66-71. doi: 10.1016/j.ymgme.2012.07.007. Epub 2012 Jul 20.

PMID:
22854512
13.

Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development.

Ortega MC, Cases O, Merchán P, Kozyraki R, Clemente D, de Castro F.

Glia. 2012 May;60(6):851-66. doi: 10.1002/glia.22316. Epub 2012 Feb 21.

PMID:
22354480
14.

Mouse model of proximal tubule endocytic dysfunction.

Weyer K, Storm T, Shan J, Vainio S, Kozyraki R, Verroust PJ, Christensen EI, Nielsen R.

Nephrol Dial Transplant. 2011 Nov;26(11):3446-51. doi: 10.1093/ndt/gfr525. Epub 2011 Sep 16.

PMID:
21926402
15.

Cubilin is essential for albumin reabsorption in the renal proximal tubule.

Amsellem S, Gburek J, Hamard G, Nielsen R, Willnow TE, Devuyst O, Nexo E, Verroust PJ, Christensen EI, Kozyraki R.

J Am Soc Nephrol. 2010 Nov;21(11):1859-67. doi: 10.1681/ASN.2010050492. Epub 2010 Aug 26.

16.

Albumin endocytosis via megalin in astrocytes is caveola- and Dab-1 dependent and is required for the synthesis of the neurotrophic factor oleic acid.

Bento-Abreu A, Velasco A, Polo-Hernández E, Lillo C, Kozyraki R, Tabernero A, Medina JM.

J Neurochem. 2009 Oct;111(1):49-60. doi: 10.1111/j.1471-4159.2009.06304.x. Epub 2009 Jul 25.

17.

The particles of the embryonic cerebrospinal fluid: how could they influence brain development?

Bachy I, Kozyraki R, Wassef M.

Brain Res Bull. 2008 Mar 18;75(2-4):289-94. doi: 10.1016/j.brainresbull.2007.10.010. Epub 2007 Nov 20.

PMID:
18331886
18.

Multiligand endocytosis and congenital defects: roles of cubilin, megalin and amnionless.

Kozyraki R, Gofflot F.

Curr Pharm Des. 2007;13(29):3038-46. Review.

PMID:
17979745
19.

Overlapping expression patterns of the multiligand endocytic receptors cubilin and megalin in the CNS, sensory organs and developing epithelia of the rodent embryo.

Assémat E, Châtelet F, Chandellier J, Commo F, Cases O, Verroust P, Kozyraki R.

Gene Expr Patterns. 2005 Dec;6(1):69-78. Epub 2005 Jul 18.

PMID:
16027047
20.

Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex.

Coudroy G, Gburek J, Kozyraki R, Madsen M, Trugnan G, Moestrup SK, Verroust PJ, Maurice M.

J Am Soc Nephrol. 2005 Aug;16(8):2330-7. Epub 2005 Jun 23.

21.

Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo.

Assémat E, Vinot S, Gofflot F, Linsel-Nitschke P, Illien F, Châtelet F, Verroust P, Louvet-Vallée S, Rinninger F, Kozyraki R.

Biol Reprod. 2005 May;72(5):1079-86. Epub 2004 Dec 22.

PMID:
15616221
22.

Megalin mediates renal uptake of heavy metal metallothionein complexes.

Klassen RB, Crenshaw K, Kozyraki R, Verroust PJ, Tio L, Atrian S, Allen PL, Hammond TG.

Am J Physiol Renal Physiol. 2004 Sep;287(3):F393-403. Epub 2004 May 4.

23.

[Cubilin: physiopathologic role and relationship with megalin].

Verroust PJ, Kozyraki R.

Med Sci (Paris). 2003 Mar;19(3):337-43. Review. French.

24.

The tandem endocytic receptors megalin and cubilin are important proteins in renal pathology.

Verroust PJ, Birn H, Nielsen R, Kozyraki R, Christensen EI.

Kidney Int. 2002 Sep;62(3):745-56. Review.

25.

Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).

Nykjaer A, Fyfe JC, Kozyraki R, Leheste JR, Jacobsen C, Nielsen MS, Verroust PJ, Aminoff M, de la Chapelle A, Moestrup SK, Ray R, Gliemann J, Willnow TE, Christensen EI.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13895-900.

26.

Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia.

Kozyraki R, Fyfe J, Verroust PJ, Jacobsen C, Dautry-Varsat A, Gburek J, Willnow TE, Christensen EI, Moestrup SK.

Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12491-6. Epub 2001 Oct 16.

27.

Cubilin, a multifunctional epithelial receptor: an overview.

Kozyraki R.

J Mol Med (Berl). 2001 May;79(4):161-7. Review.

PMID:
11409706
28.
29.

Physiopathologic role of cubilin and megalin.

Verroust PJ, Kozyraki R, Hammond TG, Moestrup SK, Christensen EI.

Adv Nephrol Necker Hosp. 2000;30:127-45. Review. No abstract available.

PMID:
11068639
30.

Cubilin, a high-density lipoprotein receptor.

Moestrup SK, Kozyraki R.

Curr Opin Lipidol. 2000 Apr;11(2):133-40. Review.

PMID:
10787174
32.

Molecular dissection of the intrinsic factor-vitamin B12 receptor, cubilin, discloses regions important for membrane association and ligand binding.

Kristiansen M, Kozyraki R, Jacobsen C, Nexø E, Verroust PJ, Moestrup SK.

J Biol Chem. 1999 Jul 16;274(29):20540-4.

33.

The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.

Kozyraki R, Fyfe J, Kristiansen M, Gerdes C, Jacobsen C, Cui S, Christensen EI, Aminoff M, de la Chapelle A, Krahe R, Verroust PJ, Moestrup SK.

Nat Med. 1999 Jun;5(6):656-61.

PMID:
10371504
34.

The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region.

Kozyraki R, Kristiansen M, Silahtaroglu A, Hansen C, Jacobsen C, Tommerup N, Verroust PJ, Moestrup SK.

Blood. 1998 May 15;91(10):3593-600. Erratum in: Blood 1998 Oct 1;92(7):2608.

35.

The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins.

Moestrup SK, Kozyraki R, Kristiansen M, Kaysen JH, Rasmussen HH, Brault D, Pontillon F, Goda FO, Christensen EI, Hammond TG, Verroust PJ.

J Biol Chem. 1998 Feb 27;273(9):5235-42.

36.

Expression of cadherins and alpha-catenin in primary epithelial tumors of the liver.

Kozyraki R, Scoazec JY, Flejou JF, D'Errico A, Bedossa P, Terris B, Fiorentino M, Bringuier AF, Grigioni WF, Feldmann G.

Gastroenterology. 1996 Apr;110(4):1137-49.

PMID:
8613003
37.

Focal nodular hyperplasia of the liver: composition of the extracellular matrix and expression of cell-cell and cell-matrix adhesion molecules.

Scoazec JY, Flejou JF, D'Errico A, Couvelard A, Kozyraki R, Fiorentino M, Grigioni WF, Feldmann G.

Hum Pathol. 1995 Oct;26(10):1114-25.

PMID:
7557945

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