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Items: 1 to 50 of 90

1.

Wnt/β-catenin signalling is necessary for gut differentiation in a marine annelid, Platynereis dumerilii.

Žídek R, Machoň O, Kozmik Z.

Evodevo. 2018 Jun 11;9:14. doi: 10.1186/s13227-018-0100-7. eCollection 2018.

2.

Tcf7L2 is essential for neurogenesis in the developing mouse neocortex.

Chodelkova O, Masek J, Korinek V, Kozmik Z, Machon O.

Neural Dev. 2018 May 11;13(1):8. doi: 10.1186/s13064-018-0107-8.

3.

Asymmetric pitx2 expression in medaka epithalamus is regulated by nodal signaling through an intronic enhancer.

Soukup V, Mrstakova S, Kozmik Z.

Dev Genes Evol. 2018 Mar;228(2):131-139. doi: 10.1007/s00427-018-0611-1. Epub 2018 Apr 16.

PMID:
29663064
4.

The role of transposable elements in functional evolution of amphioxus genome: the case of opsin gene family.

Pantzartzi CN, Pergner J, Kozmik Z.

Sci Rep. 2018 Feb 6;8(1):2506. doi: 10.1038/s41598-018-20683-9.

5.

Novel polyclonal antibodies as a useful tool for expression studies in amphioxus embryos.

Bozzo M, Pergner J, Kozmik Z, Kozmikova I.

Int J Dev Biol. 2017;61(10-11-12):793-800. doi: 10.1387/ijdb.170259ik.

6.

The opsin repertoire of the European lancelet: a window into light detection in a basal chordate.

Pantzartzi CN, Pergner J, Kozmikova I, Kozmik Z.

Int J Dev Biol. 2017;61(10-11-12):763-772. doi: 10.1387/ijdb.170139zk.

7.

Amphioxus photoreceptors - insights into the evolution of vertebrate opsins, vision and circadian rhythmicity.

Pergner J, Kozmik Z.

Int J Dev Biol. 2017;61(10-11-12):665-681. doi: 10.1387/ijdb.170230zk.

8.

The Amphioxus Model System.

Kozmik Z.

Int J Dev Biol. 2017;61(10-11-12):571-574. doi: 10.1387/ijdb.170332zk.

9.

The Bmp signaling pathway regulates development of left-right asymmetry in amphioxus.

Soukup V, Kozmik Z.

Dev Biol. 2018 Feb 1;434(1):164-174. doi: 10.1016/j.ydbio.2017.12.004. Epub 2017 Dec 7.

PMID:
29224891
10.

Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation.

Fujimura N, Kuzelova A, Ebert A, Strnad H, Lachova J, Machon O, Busslinger M, Kozmik Z.

Dev Biol. 2018 Jan 1;433(1):47-60. doi: 10.1016/j.ydbio.2017.11.004. Epub 2017 Nov 12.

PMID:
29137925
11.

The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6.

Antosova B, Smolikova J, Klimova L, Lachova J, Bendova M, Kozmikova I, Machon O, Kozmik Z.

PLoS Genet. 2016 Dec 5;12(12):e1006441. doi: 10.1371/journal.pgen.1006441. eCollection 2016 Dec.

12.

Manipulating Wnt signaling at different subcellular levels affects the fate of neonatal neural stem/progenitor cells.

Kriska J, Honsa P, Dzamba D, Butenko O, Kolenicova D, Janeckova L, Nahacka Z, Andera L, Kozmik Z, Taketo MM, Korinek V, Anderova M.

Brain Res. 2016 Nov 15;1651:73-87. doi: 10.1016/j.brainres.2016.09.026. Epub 2016 Sep 19.

PMID:
27659965
13.

Conserved Noncoding Elements in the Most Distant Genera of Cephalochordates: The Goldilocks Principle.

Yue JX, Kozmikova I, Ono H, Nossa CW, Kozmik Z, Putnam NH, Yu JK, Holland LZ.

Genome Biol Evol. 2016 Aug 25;8(8):2387-405. doi: 10.1093/gbe/evw158.

14.

Tcf7l1 protects the anterior neural fold from adopting the neural crest fate.

Mašek J, Machoň O, Kořínek V, Taketo MM, Kozmik Z.

Development. 2016 Jun 15;143(12):2206-16. doi: 10.1242/dev.132357.

15.

Zoology: A New Mouth for Amphioxus.

Soukup V, Kozmik Z.

Curr Biol. 2016 May 9;26(9):R367-8. doi: 10.1016/j.cub.2016.03.016.

16.

vox homeobox gene: a novel regulator of midbrain-hindbrain boundary development in medaka fish?

Fabian P, Pantzartzi CN, Kozmikova I, Kozmik Z.

Dev Genes Evol. 2016 Mar;226(2):99-107. doi: 10.1007/s00427-016-0533-8. Epub 2016 Mar 10.

PMID:
26965282
17.

Non-essential role for cilia in coordinating precise alignment of lens fibres.

Sugiyama Y, Shelley EJ, Yoder BK, Kozmik Z, May-Simera HL, Beales PL, Lovicu FJ, McAvoy JW.

Mech Dev. 2016 Feb;139:10-7. doi: 10.1016/j.mod.2016.01.003. Epub 2016 Jan 26.

18.

Autosomal-Dominant Corneal Endothelial Dystrophies CHED1 and PPCD1 Are Allelic Disorders Caused by Non-coding Mutations in the Promoter of OVOL2.

Davidson AE, Liskova P, Evans CJ, Dudakova L, Nosková L, Pontikos N, Hartmannová H, Hodaňová K, Stránecký V, Kozmík Z, Levis HJ, Idigo N, Sasai N, Maher GJ, Bellingham J, Veli N, Ebenezer ND, Cheetham ME, Daniels JT, Thaung CM, Jirsova K, Plagnol V, Filipec M, Kmoch S, Tuft SJ, Hardcastle AJ.

Am J Hum Genet. 2016 Jan 7;98(1):75-89. doi: 10.1016/j.ajhg.2015.11.018. Epub 2015 Dec 31.

19.

Meis2 is essential for cranial and cardiac neural crest development.

Machon O, Masek J, Machonova O, Krauss S, Kozmik Z.

BMC Dev Biol. 2015 Nov 6;15:40. doi: 10.1186/s12861-015-0093-6.

20.

Corrigendum: Cubozoan genome illuminates functional diversification of opsins and photoreceptor evolution.

Liegertová M, Pergner J, Kozmiková I, Fabian P, Pombinho AR, Strnad H, Pačes J, Vlček Č, Bartůněk P, Kozmik Z.

Sci Rep. 2015 Sep 24;5:14396. doi: 10.1038/srep14396. No abstract available.

21.

Pax2/5/8 and Pax6 alternative splicing events in basal chordates and vertebrates: a focus on paired box domain.

Fabian P, Kozmikova I, Kozmik Z, Pantzartzi CN.

Front Genet. 2015 Jul 2;6:228. doi: 10.3389/fgene.2015.00228. eCollection 2015.

22.

Cubozoan genome illuminates functional diversification of opsins and photoreceptor evolution.

Liegertová M, Pergner J, Kozmiková I, Fabian P, Pombinho AR, Strnad H, Pačes J, Vlček Č, Bartůněk P, Kozmik Z.

Sci Rep. 2015 Jul 8;5:11885. doi: 10.1038/srep11885. Erratum in: Sci Rep. 2015;5:14396.

23.

Gene regulation in amphioxus: An insight from transgenic studies in amphioxus and vertebrates.

Kozmikova I, Kozmik Z.

Mar Genomics. 2015 Dec;24 Pt 2:159-66. doi: 10.1016/j.margen.2015.06.003. Epub 2015 Jun 18. Review.

PMID:
26094865
24.

The Nodal signaling pathway controls left-right asymmetric development in amphioxus.

Soukup V, Yong LW, Lu TM, Huang SW, Kozmik Z, Yu JK.

Evodevo. 2015 Feb 17;6:5. doi: 10.1186/2041-9139-6-5. eCollection 2015.

25.

Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.

Klimova L, Antosova B, Kuzelova A, Strnad H, Kozmik Z.

Dev Biol. 2015 Jun 1;402(1):48-60. doi: 10.1016/j.ydbio.2015.02.023. Epub 2015 Mar 18.

26.

Genetic interaction between Pax6 and β-catenin in the developing retinal pigment epithelium.

Fujimura N, Klimova L, Antosova B, Smolikova J, Machon O, Kozmik Z.

Dev Genes Evol. 2015 Apr;225(2):121-8. doi: 10.1007/s00427-015-0493-4. Epub 2015 Feb 18.

PMID:
25689933
27.

Stage-dependent requirement of neuroretinal Pax6 for lens and retina development.

Klimova L, Kozmik Z.

Development. 2014 Mar;141(6):1292-302. doi: 10.1242/dev.098822. Epub 2014 Feb 12.

28.

A novel N-terminal motif is responsible for the evolution of neural crest-specific gene-regulatory activity in vertebrate FoxD3.

Ono H, Kozmik Z, Yu JK, Wada H.

Dev Biol. 2014 Jan 15;385(2):396-404. doi: 10.1016/j.ydbio.2013.11.010. Epub 2013 Nov 16.

29.

Ectopic activation of Wnt/β-catenin signaling in lens fiber cells results in cataract formation and aberrant fiber cell differentiation.

Antosova B, Smolikova J, Borkovcova R, Strnad H, Lachova J, Machon O, Kozmik Z.

PLoS One. 2013 Oct 30;8(10):e78279. doi: 10.1371/journal.pone.0078279. eCollection 2013.

30.

Essential role of Bmp signaling and its positive feedback loop in the early cell fate evolution of chordates.

Kozmikova I, Candiani S, Fabian P, Gurska D, Kozmik Z.

Dev Biol. 2013 Oct 15;382(2):538-54. doi: 10.1016/j.ydbio.2013.07.021. Epub 2013 Aug 7.

31.

Generation of mRx-Cre transgenic mouse line for efficient conditional gene deletion in early retinal progenitors.

Klimova L, Lachova J, Machon O, Sedlacek R, Kozmik Z.

PLoS One. 2013 May 7;8(5):e63029. doi: 10.1371/journal.pone.0063029. Print 2013.

32.

Molecular analysis of the amphioxus frontal eye unravels the evolutionary origin of the retina and pigment cells of the vertebrate eye.

Vopalensky P, Pergner J, Liegertova M, Benito-Gutierrez E, Arendt D, Kozmik Z.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15383-8. Epub 2012 Sep 4.

33.

The function and developmental expression of alternatively spliced isoforms of amphioxus and Xenopus laevis Pax2/5/8 genes: revealing divergence at the invertebrate to vertebrate transition.

Short S, Kozmik Z, Holland LZ.

J Exp Zool B Mol Dev Evol. 2012 Nov;318(7):555-71. doi: 10.1002/jez.b.22460. Epub 2012 Jul 12.

PMID:
22791613
34.

Shh expression in a rudimentary tooth offers new insights into development of the mouse incisor.

Hovorakova M, Prochazka J, Lesot H, Smrckova L, Churava S, Boran T, Kozmik Z, Klein O, Peterkova R, Peterka M.

J Exp Zool B Mol Dev Evol. 2011 Jul 15;316(5):347-58. doi: 10.1002/jez.b.21408. Epub 2011 Mar 31.

PMID:
21455944
35.

Conservation and diversification of an ancestral chordate gene regulatory network for dorsoventral patterning.

Kozmikova I, Smolikova J, Vlcek C, Kozmik Z.

PLoS One. 2011 Feb 3;6(2):e14650. doi: 10.1371/journal.pone.0014650.

36.

A lens-specific co-injection marker for medaka transgenesis.

Vopalensky P, Ruzickova J, Pavlu B, Kozmik Z.

Biotechniques. 2010 Mar;48(3):235-6. doi: 10.2144/000113368.

37.

Lens morphogenesis is dependent on Pax6-mediated inhibition of the canonical Wnt/beta-catenin signaling in the lens surface ectoderm.

Machon O, Kreslova J, Ruzickova J, Vacik T, Klimova L, Fujimura N, Lachova J, Kozmik Z.

Genesis. 2010 Feb;48(2):86-95. doi: 10.1002/dvg.20583.

PMID:
20027618
38.

Eye evolution: common use and independent recruitment of genetic components.

Vopalensky P, Kozmik Z.

Philos Trans R Soc Lond B Biol Sci. 2009 Oct 12;364(1531):2819-32. doi: 10.1098/rstb.2009.0079. Review.

39.

Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium.

Fujimura N, Taketo MM, Mori M, Korinek V, Kozmik Z.

Dev Biol. 2009 Oct 1;334(1):31-45. doi: 10.1016/j.ydbio.2009.07.002. Epub 2009 Jul 9.

40.

Eye-specific expression of an ancestral jellyfish PaxB gene interferes with Pax6 function despite its conserved Pax6/Pax2 characteristics.

Ruzickova J, Piatigorsky J, Kozmik Z.

Int J Dev Biol. 2009;53(4):469-82. doi: 10.1387/ijdb.082793jr.

41.

Assembly of the cnidarian camera-type eye from vertebrate-like components.

Kozmik Z, Ruzickova J, Jonasova K, Matsumoto Y, Vopalensky P, Kozmikova I, Strnad H, Kawamura S, Piatigorsky J, Paces V, Vlcek C.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8989-93. doi: 10.1073/pnas.0800388105. Epub 2008 Jun 24.

42.

The amphioxus genome illuminates vertebrate origins and cephalochordate biology.

Holland LZ, Albalat R, Azumi K, Benito-Gutiérrez E, Blow MJ, Bronner-Fraser M, Brunet F, Butts T, Candiani S, Dishaw LJ, Ferrier DE, Garcia-Fernàndez J, Gibson-Brown JJ, Gissi C, Godzik A, Hallböök F, Hirose D, Hosomichi K, Ikuta T, Inoko H, Kasahara M, Kasamatsu J, Kawashima T, Kimura A, Kobayashi M, Kozmik Z, Kubokawa K, Laudet V, Litman GW, McHardy AC, Meulemans D, Nonaka M, Olinski RP, Pancer Z, Pennacchio LA, Pestarino M, Rast JP, Rigoutsos I, Robinson-Rechavi M, Roch G, Saiga H, Sasakura Y, Satake M, Satou Y, Schubert M, Sherwood N, Shiina T, Takatori N, Tello J, Vopalensky P, Wada S, Xu A, Ye Y, Yoshida K, Yoshizaki F, Yu JK, Zhang Q, Zmasek CM, de Jong PJ, Osoegawa K, Putnam NH, Rokhsar DS, Satoh N, Holland PW.

Genome Res. 2008 Jul;18(7):1100-11. doi: 10.1101/gr.073676.107. Epub 2008 Jun 18. Erratum in: Genome Res. 2008 Aug;18(8):1380.

43.

The role of Pax genes in eye evolution.

Kozmik Z.

Brain Res Bull. 2008 Mar 18;75(2-4):335-9. doi: 10.1016/j.brainresbull.2007.10.046. Epub 2007 Nov 20. Review.

PMID:
18331895
44.

Cubozoan crystallins: evidence for convergent evolution of pax regulatory sequences.

Kozmik Z, Swamynathan SK, Ruzickova J, Jonasova K, Paces V, Vlcek C, Piatigorsky J.

Evol Dev. 2008 Jan-Feb;10(1):52-61. doi: 10.1111/j.1525-142X.2007.00213.x.

PMID:
18184357
45.

Eye evolution: lens and cornea as an upgrade of animal visual system.

Jonasova K, Kozmik Z.

Semin Cell Dev Biol. 2008 Apr;19(2):71-81. Epub 2007 Oct 13. Review.

PMID:
18035562
46.

A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus.

Machon O, Backman M, Machonova O, Kozmik Z, Vacik T, Andersen L, Krauss S.

Dev Biol. 2007 Nov 1;311(1):223-37. Epub 2007 Aug 28.

47.

Pax-Six-Eya-Dach network during amphioxus development: conservation in vitro but context specificity in vivo.

Kozmik Z, Holland ND, Kreslova J, Oliveri D, Schubert M, Jonasova K, Holland LZ, Pestarino M, Benes V, Candiani S.

Dev Biol. 2007 Jun 1;306(1):143-59. Epub 2007 Mar 13.

48.

Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function.

Kreslova J, Machon O, Ruzickova J, Lachova J, Wawrousek EF, Kemler R, Krauss S, Piatigorsky J, Kozmik Z.

Genesis. 2007 Apr;45(4):157-68.

PMID:
17410548
49.

Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5.

Fujimura N, Vacik T, Machon O, Vlcek C, Scalabrin S, Speth M, Diep D, Krauss S, Kozmik Z.

J Biol Chem. 2007 Jan 12;282(2):1225-37. Epub 2006 Nov 6.

50.

The cellular fate of cortical progenitors is not maintained in neurosphere cultures.

Machon O, Backman M, Krauss S, Kozmik Z.

Mol Cell Neurosci. 2005 Nov;30(3):388-97. Epub 2005 Sep 8.

PMID:
16150605

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