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Items: 5

1.

Pharmacological Characterization of a Novel 5-Hydroxybenzothiazolone-Derived β 2-Adrenoceptor Agonist with Functional Selectivity for Anabolic Effects on Skeletal Muscle Resulting in a Wider Cardiovascular Safety Window in Preclinical Studies.

Koziczak-Holbro M, Rigel DF, Dumotier B, Sykes DA, Tsao J, Nguyen NH, Bösch J, Jourdain M, Flotte L, Adachi Y, Kiffe M, Azria M, Fairhurst RA, Charlton SJ, Richardson BP, Lach-Trifilieff E, Glass DJ, Ullrich T, Hatakeyama S.

J Pharmacol Exp Ther. 2019 May;369(2):188-199. doi: 10.1124/jpet.118.255307. Epub 2019 Feb 28.

PMID:
30819762
2.

The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation.

Koziczak-Holbro M, Littlewood-Evans A, Pöllinger B, Kovarik J, Dawson J, Zenke G, Burkhart C, Müller M, Gram H.

Arthritis Rheum. 2009 Jun;60(6):1661-71. doi: 10.1002/art.24552.

3.

Solving the IRAK-4 enigma: application of kinase-dead knock-in mice.

Koziczak-Holbro M, Joyce C, Glück A, Kinzel B, Müller M, Gram H.

Ernst Schering Found Symp Proc. 2007;(3):63-82.

PMID:
18510099
4.

IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes.

Koziczak-Holbro M, Glück A, Tschopp C, Mathison JC, Gram H.

Eur J Immunol. 2008 Mar;38(3):788-96. doi: 10.1002/eji.200737886.

5.

IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression.

Koziczak-Holbro M, Joyce C, Glück A, Kinzel B, Müller M, Tschopp C, Mathison JC, Davis CN, Gram H.

J Biol Chem. 2007 May 4;282(18):13552-60. Epub 2007 Mar 2.

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