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Items: 1 to 50 of 127

1.

Role of G protein-regulated inducer of neurite outgrowth 3 (GRIN3) in β-arrestin 2-Akt signaling and dopaminergic behaviors.

Mototani Y, Okamura T, Goto M, Shimizu Y, Yanobu-Takanashi R, Ito A, Kawamura N, Yagisawa Y, Umeki D, Nariyama M, Suita K, Ohnuki Y, Shiozawa K, Sahara Y, Kozasa T, Saeki Y, Okumura S.

Pflugers Arch. 2018 Jun;470(6):937-947. doi: 10.1007/s00424-018-2124-1. Epub 2018 Mar 2.

PMID:
29500670
2.

Visualization of ligand-induced Gi-protein activation in chemotaxing cells.

Masuda K, Kitakami JI, Kozasa T, Kodama T, Ihara S, Hamakubo T.

FASEB J. 2017 Mar;31(3):910-919. doi: 10.1096/fj.201601102R. Epub 2016 Nov 23.

PMID:
27881485
3.

Analysis of a pair of END+ and END- viruses derived from the same bovine viral diarrhea virus stock reveals the amino acid determinants in Npro responsible for inhibition of type I interferon production.

Kozasa T, Abe Y, Mitsuhashi K, Tamura T, Aoki H, Ishimaru M, Nakamura S, Okamatsu M, Kida H, Sakoda Y.

J Vet Med Sci. 2015 May;77(5):511-8. doi: 10.1292/jvms.14-0420. Epub 2014 Dec 28.

4.

Molecular, biological, and antigenic characterization of a Border disease virus isolated from a pig during classical swine fever surveillance in Japan.

Nagai M, Aoki H, Sakoda Y, Kozasa T, Tominaga-Teshima K, Mine J, Abe Y, Tamura T, Kobayashi T, Nishine K, Tateishi K, Suzuki Y, Fukuhara M, Ohmori K, Todaka R, Katayama K, Mizutani T, Nakamura S, Kida H, Shirai J.

J Vet Diagn Invest. 2014 Jul;26(4):547-552. doi: 10.1177/1040638714541837.

PMID:
25027496
5.

Gα13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration.

Patel M, Kawano T, Suzuki N, Hamakubo T, Karginov AV, Kozasa T.

Mol Pharmacol. 2014 Sep;86(3):252-62. doi: 10.1124/mol.114.093914. Epub 2014 Jun 23. Erratum in: Mol Pharmacol. 2015 Nov;88(5):880.

6.

Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation.

Gan X, Wang C, Patel M, Kreutz B, Zhou M, Kozasa T, Wu D.

J Biol Chem. 2013 Nov 22;288(47):33978-84. doi: 10.1074/jbc.M113.477406. Epub 2013 Oct 10.

7.

G protein-dependent basal and evoked endothelial cell vWF secretion.

Rusu L, Andreeva A, Visintine DJ, Kim K, Vogel SM, Stojanovic-Terpo A, Chernaya O, Liu G, Bakhshi FR, Haberichter SL, Iwanari H, Kusano-Arai O, Suzuki N, Hamakubo T, Kozasa T, Cho J, Du X, Minshall RD.

Blood. 2014 Jan 16;123(3):442-50. doi: 10.1182/blood-2013-03-489351. Epub 2013 Sep 30.

8.

A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels.

Mahajan R, Ha J, Zhang M, Kawano T, Kozasa T, Logothetis DE.

Sci Signal. 2013 Aug 13;6(288):ra69. doi: 10.1126/scisignal.2004075.

9.

Modification of p115RhoGEF Ser(330) regulates its RhoGEF activity.

Chow CR, Suzuki N, Kawamura T, Hamakubo T, Kozasa T.

Cell Signal. 2013 Nov;25(11):2085-92. doi: 10.1016/j.cellsig.2013.06.012. Epub 2013 Jun 29.

10.

Structural and functional analysis of the regulator of G protein signaling 2-gαq complex.

Nance MR, Kreutz B, Tesmer VM, Sterne-Marr R, Kozasa T, Tesmer JJ.

Structure. 2013 Mar 5;21(3):438-48. doi: 10.1016/j.str.2012.12.016. Epub 2013 Feb 21.

11.

Thermodynamic and structural properties of the specific binding between Ag⁺ ion and C:C mismatched base pair in duplex DNA to form C-Ag-C metal-mediated base pair.

Torigoe H, Okamoto I, Dairaku T, Tanaka Y, Ono A, Kozasa T.

Biochimie. 2012 Nov;94(11):2431-40. doi: 10.1016/j.biochi.2012.06.024. Epub 2012 Jul 3.

PMID:
22766014
12.

PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12.

Gan X, Wang J, Wang C, Sommer E, Kozasa T, Srinivasula S, Alessi D, Offermanns S, Simon MI, Wu D.

Nat Cell Biol. 2012 May 20;14(7):686-96. doi: 10.1038/ncb2507.

13.

Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13.

Kozasa T, Hajicek N, Chow CR, Suzuki N.

J Biochem. 2011 Oct;150(4):357-69. doi: 10.1093/jb/mvr105. Epub 2011 Aug 26. Review.

14.

Methods to select suitable fetal bovine serum for use in quality control assays for the detection of adventitious viruses from biological products.

Kozasa T, Aoki H, Nakajima N, Fukusho A, Ishimaru M, Nakamura S.

Biologicals. 2011 Jul;39(4):242-8. doi: 10.1016/j.biologicals.2011.06.001. Epub 2011 Jun 30.

PMID:
21719306
15.

Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex.

Hajicek N, Kukimoto-Niino M, Mishima-Tsumagari C, Chow CR, Shirouzu M, Terada T, Patel M, Yokoyama S, Kozasa T.

J Biol Chem. 2011 Jun 10;286(23):20625-36. doi: 10.1074/jbc.M110.201392. Epub 2011 Apr 20.

16.

Thermodynamic properties of the specific binding between Ag+ ions and C:C mismatched base pairs in duplex DNA.

Torigoe H, Miyakawa Y, Ono A, Kozasa T.

Nucleosides Nucleotides Nucleic Acids. 2011 Feb;30(2):149-67. doi: 10.1080/15257770.2011.553210.

PMID:
21360412
17.

Kinetic scaffolding mediated by a phospholipase C-beta and Gq signaling complex.

Waldo GL, Ricks TK, Hicks SN, Cheever ML, Kawano T, Tsuboi K, Wang X, Montell C, Kozasa T, Sondek J, Harden TK.

Science. 2010 Nov 12;330(6006):974-80. doi: 10.1126/science.1193438. Epub 2010 Oct 21.

18.

Hg(II) ion specifically binds with T:T mismatched base pair in duplex DNA.

Torigoe H, Ono A, Kozasa T.

Chemistry. 2010 Nov 22;16(44):13218-25. doi: 10.1002/chem.201001171.

PMID:
20886468
19.

Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity.

Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E.

Sci Signal. 2010 May 11;3(121):ra37. doi: 10.1126/scisignal.2000647.

20.

G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling.

Gong H, Shen B, Flevaris P, Chow C, Lam SC, Voyno-Yasenetskaya TA, Kozasa T, Du X.

Science. 2010 Jan 15;327(5963):340-3. doi: 10.1126/science.1174779.

21.

Interaction between tetraplex structure of yeast telomeric DNA and tetraplex-binding ligand.

Torigoe H, Horio E, Takehara T, Kaneda K, Kozasa T.

Nucleic Acids Symp Ser (Oxf). 2009;(53):243-4. doi: 10.1093/nass/nrp122.

PMID:
19749351
22.

Tetraplex structure of budding yeast telomeric DNA.

Torigoe H, Horio E, Takehara T, Kaneda K, Kozasa T.

Nucleic Acids Symp Ser (Oxf). 2009;(53):235-6. doi: 10.1093/nass/nrp118.

PMID:
19749347
23.

Development of a novel method to determine the concentration of heavy metal cations: application of the specific interaction between heavy metal cation and mismatch DNA base pair.

Kozasa T, Miyakawa Y, Fukushi M, Ono A, Torigoe H.

Nucleic Acids Symp Ser (Oxf). 2009;(53):179-80. doi: 10.1093/nass/nrp090.

PMID:
19749319
24.

Development of a novel device to trap heavy metal cations: application of the specific interaction between heavy metal cation and mismatch DNA base pair.

Torigoe H, Miyakawa Y, Fukushi M, Ono A, Kozasa T.

Nucleic Acids Symp Ser (Oxf). 2009;(53):23-4. doi: 10.1093/nass/nrp012.

PMID:
19749241
25.

Regulation and physiological functions of G12/13-mediated signaling pathways.

Suzuki N, Hajicek N, Kozasa T.

Neurosignals. 2009;17(1):55-70. doi: 10.1159/000186690. Epub 2009 Feb 12. Review.

26.

Origin of the voltage dependence of G-protein regulation of P/Q-type Ca2+ channels.

Zhang Y, Chen YH, Bangaru SD, He L, Abele K, Tanabe S, Kozasa T, Yang J.

J Neurosci. 2008 Dec 24;28(52):14176-88. doi: 10.1523/JNEUROSCI.1350-08.2008.

27.

Activation of leukemia-associated RhoGEF by Galpha13 with significant conformational rearrangements in the interface.

Suzuki N, Tsumoto K, Hajicek N, Daigo K, Tokita R, Minami S, Kodama T, Hamakubo T, Kozasa T.

J Biol Chem. 2009 Feb 20;284(8):5000-9. doi: 10.1074/jbc.M804073200. Epub 2008 Dec 12.

28.

Assembly of high order G alpha q-effector complexes with RGS proteins.

Shankaranarayanan A, Thal DM, Tesmer VM, Roman DL, Neubig RR, Kozasa T, Tesmer JJ.

J Biol Chem. 2008 Dec 12;283(50):34923-34. doi: 10.1074/jbc.M805860200. Epub 2008 Oct 20.

29.

A taxonomic study on erysipelothrix by DNA-DNA hybridization experiments with numerous strains isolated from extensive origins.

Takahashi T, Fujisawa T, Umeno A, Kozasa T, Yamamoto K, Sawada T.

Microbiol Immunol. 2008 Oct;52(10):469-78. doi: 10.1111/j.1348-0421.2008.00061.x.

30.

The specific interaction between metal cation and mismatch base pair in duplex RNA.

Kozasa T, Miyakawa Y, Ono A, Torigoe H.

Nucleic Acids Symp Ser (Oxf). 2008;(52):197-8. doi: 10.1093/nass/nrn100.

PMID:
18776321
31.
32.
33.

The specific interaction between two T:T mismatch base pairs and mercury (II) cation.

Torigoe H, Miyakawa Y, Kozasa T, Ono A.

Nucleic Acids Symp Ser (Oxf). 2007;(51):185-6.

PMID:
18029648
34.

The specific interaction between two C:C mismatch base pairs and silver (I) cation.

Torigoe H, Kozasa T, Ono A.

Nucleic Acids Symp Ser (Oxf). 2007;(51):183-4.

PMID:
18029647
35.

Genomic analyses of bovine viral diarrhea viruses isolated from cattle imported into Japan between 1991 and 2005.

Yamamoto T, Kozasa T, Aoki H, Sekiguchi H, Morino S, Nakamura S.

Vet Microbiol. 2008 Mar 18;127(3-4):386-91. Epub 2007 Aug 19.

PMID:
17881158
36.

Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain.

Rojas RJ, Yohe ME, Gershburg S, Kawano T, Kozasa T, Sondek J.

J Biol Chem. 2007 Oct 5;282(40):29201-10. Epub 2007 Jul 2.

37.

Distinct regions of Galpha13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs.

Kreutz B, Hajicek N, Yau DM, Nakamura S, Kozasa T.

Cell Signal. 2007 Aug;19(8):1681-9. Epub 2007 Mar 15.

PMID:
17449226
38.
39.

Interaction of Galphaq and Kir3, G protein-coupled inwardly rectifying potassium channels.

Kawano T, Zhao P, Floreani CV, Nakajima Y, Kozasa T, Nakajima S.

Mol Pharmacol. 2007 Apr;71(4):1179-84. Epub 2007 Feb 12.

PMID:
17296805
40.

Thermodynamic analyses of the specific interaction between two C:C mismatch base pairs and silver (I) cations.

Torigoe H, Miyakawa Y, Nagasawa N, Kozasa T, Ono A.

Nucleic Acids Symp Ser (Oxf). 2006;(50):225-6.

PMID:
17150899
43.
44.

Computational evaluation of the specific interaction between cation and mismatch base pair.

Sugiyama H, Adachi N, Kawauchi S, Kozasa T, Katayama T, Torigoe H, Ono A, Tamura Y.

Nucleic Acids Symp Ser (Oxf). 2005;(49):215-6.

PMID:
17150710
45.

Dominant negative effects of a Gbeta mutant on G-protein coupled inward rectifier K+ channel.

Zhao Q, Albsoul-Younes AM, Zhao P, Kozasa T, Nakajima Y, Nakajima S.

FEBS Lett. 2006 Jul 10;580(16):3879-82. Epub 2006 Jun 16.

46.

Activation state-dependent interaction between Galphai and p67phox.

Marty C, Kozasa T, Quinn MT, Ye RD.

Mol Cell Biol. 2006 Jul;26(13):5190-200.

47.

A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteins.

Kreutz B, Yau DM, Nance MR, Tanabe S, Tesmer JJ, Kozasa T.

Biochemistry. 2006 Jan 10;45(1):167-74.

48.

Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex.

Tesmer VM, Kawano T, Shankaranarayanan A, Kozasa T, Tesmer JJ.

Science. 2005 Dec 9;310(5754):1686-90.

50.

G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus.

Kino T, Tiulpakov A, Ichijo T, Chheng L, Kozasa T, Chrousos GP.

J Cell Biol. 2005 Jun 20;169(6):885-96. Epub 2005 Jun 13.

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