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Items: 1 to 50 of 163

1.

Discovery of Selective M4 Muscarinic Acetylcholine Receptor Agonists with Novel Carbamate Isosteres.

Yang Q, Lachapelle EA, Kablaoui NM, Webb D, Popiolek M, Grimwood S, Kozak R, O'Connor RE, Lazzaro JT, Butler CR, Zhang L.

ACS Med Chem Lett. 2019 May 28;10(6):941-948. doi: 10.1021/acsmedchemlett.9b00106. eCollection 2019 Jun 13.

PMID:
31223452
2.

Public trust and knowledge in the context of emerging climate-adaptive forestry policies.

Peterson St-Laurent G, Hagerman S, Findlater KM, Kozak R.

J Environ Manage. 2019 Jul 15;242:474-486. doi: 10.1016/j.jenvman.2019.04.065. Epub 2019 May 7.

PMID:
31075642
3.

A novel dopamine D1 receptor agonist excites delay-dependent working memory-related neuronal firing in primate dorsolateral prefrontal cortex.

Wang M, Datta D, Enwright J, Galvin V, Yang ST, Paspalas C, Kozak R, Gray DL, Lewis DA, Arnsten AFT.

Neuropharmacology. 2019 May 15;150:46-58. doi: 10.1016/j.neuropharm.2019.03.001. Epub 2019 Mar 8.

4.

Improved and semi-automated reductive β-elimination workflow for higher throughput protein O-glycosylation analysis.

Kotsias M, Kozak RP, Gardner RA, Wuhrer M, Spencer DIR.

PLoS One. 2019 Jan 17;14(1):e0210759. doi: 10.1371/journal.pone.0210759. eCollection 2019.

5.

Emerging antimicrobial resistance among Escherichia coli strains in bloodstream infections in Toronto, 2006-2016: a retrospective cohort study.

Mineau S, Kozak R, Kissoon M, Paterson A, Oppedisano A, Douri F, Gogan K, Willey BM, McGeer A, Poutanen SM.

CMAJ Open. 2018 Dec 3;6(4):E580-E586. doi: 10.9778/cmajo.20180039. Print 2018 Oct-Dec.

6.

Transcriptional activation of fucosyltransferase (FUT) genes using the CRISPR-dCas9-VPR technology reveals potent N-glycome alterations in colorectal cancer cells.

Blanas A, Cornelissen LAM, Kotsias M, van der Horst JC, van de Vrugt HJ, Kalay H, Spencer DIR, Kozak RP, van Vliet SJ.

Glycobiology. 2019 Feb 1;29(2):137-150. doi: 10.1093/glycob/cwy096.

7.

Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization.

Davoren JE, Nason D, Coe J, Dlugolenski K, Helal C, Harris AR, LaChapelle E, Liang S, Liu Y, O'Connor R, Orozco CC, Rai BK, Salafia M, Samas B, Xu W, Kozak R, Gray D.

J Med Chem. 2018 Dec 27;61(24):11384-11397. doi: 10.1021/acs.jmedchem.8b01622. Epub 2018 Dec 11.

PMID:
30431269
8.

Relating constructs of attention and working memory to social withdrawal in Alzheimer's disease and schizophrenia: issues regarding paradigm selection.

Gilmour G, Porcelli S, Bertaina-Anglade V, Arce E, Dukart J, Hayen A, Lobo A, Lopez-Anton R, Merlo Pich E, Pemberton DJ, Havenith MN, Glennon JC, Harel BT, Dawson G, Marston H, Kozak R, Serretti A.

Neurosci Biobehav Rev. 2019 Feb;97:47-69. doi: 10.1016/j.neubiorev.2018.09.025. Epub 2018 Nov 3. Review.

9.

In Vivo Modulation of Hippocampal Excitability by M4 Muscarinic Acetylcholine Receptor Activator: Implications for Treatment of Alzheimer's Disease and Schizophrenic Patients.

Popiolek M, Mandelblat-Cerf Y, Young D, Garst-Orozco J, Lotarski SM, Stark E, Kramer M, Butler CR, Kozak R.

ACS Chem Neurosci. 2019 Mar 20;10(3):1091-1098. doi: 10.1021/acschemneuro.8b00496. Epub 2018 Oct 26.

PMID:
30335349
10.

Injection of Saline Into the Biopsy Tract and Rapid Patient Rollover Decreases Pneumothorax Size Following Computed Tomography-Guided Transthoracic Needle Biopsy.

Khorochkov E, Garvin GJ, Potoczny S, Kozak RI.

Can Assoc Radiol J. 2018 Nov;69(4):489-492. doi: 10.1016/j.carj.2018.08.002. Epub 2018 Oct 8.

PMID:
30309700
11.

Meta-analysis of amantadine efficacy for improving preclinical research reliability.

Stanley P, Pioli EY, Kozak R, Popiolek M, Bezard E.

Mov Disord. 2018 Oct;33(10):1555-1557. doi: 10.1002/mds.27486. Epub 2018 Oct 4. No abstract available.

PMID:
30288778
12.

Social brain, social dysfunction and social withdrawal.

Porcelli S, Van Der Wee N, van der Werff S, Aghajani M, Glennon JC, van Heukelum S, Mogavero F, Lobo A, Olivera FJ, Lobo E, Posadas M, Dukart J, Kozak R, Arce E, Ikram A, Vorstman J, Bilderbeck A, Saris I, Kas MJ, Serretti A.

Neurosci Biobehav Rev. 2019 Feb;97:10-33. doi: 10.1016/j.neubiorev.2018.09.012. Epub 2018 Sep 20. Review.

13.

Nosocomial outbreak of vanD-carrying vancomycin-resistant Enterococcus faecium.

Lam PW, Kozak RA, Eshaghi A, Avaness M, Salt N, Patel SN, Simor AE, Leis JA.

Infect Control Hosp Epidemiol. 2018 Oct;39(10):1266-1268. doi: 10.1017/ice.2018.174. Epub 2018 Aug 16. No abstract available.

PMID:
30111383
14.

A comparative study of defect formation in GaAs nanocrystals selectively grown on nanopatterned and flat Si(001) substrates.

Kozak R, Prieto I, Arroyo Rojas Dasilva Y, Erni R, von Känel H, Bona GL, Rossell MD.

Micron. 2018 Oct;113:83-90. doi: 10.1016/j.micron.2018.06.018. Epub 2018 Jul 2.

PMID:
30007860
15.

Victimization and Violence: An Exploration of the Relationship Between Child Sexual Abuse, Violence, and Delinquency.

Kozak RS, Gushwa M, Cadet TJ.

J Child Sex Abus. 2018 Aug-Sep;27(6):699-717. doi: 10.1080/10538712.2018.1474412. Epub 2018 May 24.

PMID:
29792581
16.

Public perceptions about climate change mitigation in British Columbia's forest sector.

Peterson St-Laurent G, Hagerman S, Kozak R, Hoberg G.

PLoS One. 2018 Apr 23;13(4):e0195999. doi: 10.1371/journal.pone.0195999. eCollection 2018.

17.

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor.

Gray DL, Allen JA, Mente S, O'Connor RE, DeMarco GJ, Efremov I, Tierney P, Volfson D, Davoren J, Guilmette E, Salafia M, Kozak R, Ehlers MD.

Nat Commun. 2018 Feb 14;9(1):674. doi: 10.1038/s41467-017-02776-7.

18.

Aggregate Formation of Surface-Modified Nanoparticles in Solvents and Polymer Nanocomposites.

Musino D, Genix AC, Chaussée T, Guy L, Meissner N, Kozak R, Bizien T, Oberdisse J.

Langmuir. 2018 Mar 6;34(9):3010-3020. doi: 10.1021/acs.langmuir.7b03932. Epub 2018 Feb 20.

PMID:
29443532
19.

α5 nAChR modulation of the prefrontal cortex makes attention resilient.

Howe WM, Brooks JL, Tierney PL, Pang J, Rossi A, Young D, Dlugolenski K, Guillmette E, Roy M, Hales K, Kozak R.

Brain Struct Funct. 2018 Mar;223(2):1035-1047. doi: 10.1007/s00429-017-1601-1. Epub 2018 Jan 3.

PMID:
29299690
20.

MicroRNA and mRNA Dysregulation in Astrocytes Infected with Zika Virus.

Kozak RA, Majer A, Biondi MJ, Medina SJ, Goneau LW, Sajesh BV, Slota JA, Zubach V, Severini A, Safronetz D, Hiebert SL, Beniac DR, Booth TF, Booth SA, Kobinger GP.

Viruses. 2017 Oct 14;9(10). pii: E297. doi: 10.3390/v9100297.

21.

Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry.

Qiu S, Leung A, Bo Y, Kozak RA, Anand SP, Warkentin C, Salambanga FDR, Cui J, Kobinger G, Kobasa D, Côté M.

Virology. 2018 Jan 1;513:17-28. doi: 10.1016/j.virol.2017.09.028. Epub 2017 Oct 12.

22.

Kynurenine pathway in schizophrenia: Galantamine-memantine combination for cognitive impairments.

Koola MM, Sklar J, Davis W, Nikiforuk A, Meissen JK, Sawant-Basak A, Aaronson ST, Kozak R.

Schizophr Res. 2018 Mar;193:459-460. doi: 10.1016/j.schres.2017.07.005. Epub 2017 Jul 11. No abstract available.

PMID:
28705532
23.

Replication and Oncolytic Activity of an Avian Orthoreovirus in Human Hepatocellular Carcinoma Cells.

Kozak RA, Hattin L, Biondi MJ, Corredor JC, Walsh S, Xue-Zhong M, Manuel J, McGilvray ID, Morgenstern J, Lusty E, Cherepanov V, McBey BA, Leishman D, Feld JJ, Bridle B, Nagy É.

Viruses. 2017 Apr 24;9(4). pii: E90. doi: 10.3390/v9040090.

24.

Selective Nucleation of GaAs on Si Nanofacets.

Prieto I, Kozak R, Skibitzki O, Rossell MD, Schroeder T, Erni R, von Känel H.

Small. 2017 Jun;13(22). doi: 10.1002/smll.201603122. Epub 2017 Apr 24.

PMID:
28437030
25.

Bi-modal nanoheteroepitaxy of GaAs on Si by metal organic vapor phase epitaxy.

Prieto I, Kozak R, Skibitzki O, Rossell MD, Zaumseil P, Capellini G, Gini E, Kunze K, Rojas Dasilva YA, Erni R, Schroeder T, Känel HV.

Nanotechnology. 2017 Mar 1;28(13):135701. doi: 10.1088/1361-6528/aa5ec4. Epub 2017 Feb 27.

PMID:
28240990
26.

Structural and optical characterization of GaAs nano-crystals selectively grown on Si nano-tips by MOVPE.

Skibitzki O, Prieto I, Kozak R, Capellini G, Zaumseil P, Arroyo Rojas Dasilva Y, Rossell MD, Erni R, von Känel H, Schroeder T.

Nanotechnology. 2017 Mar 1;28(13):135301. doi: 10.1088/1361-6528/aa5ec1. Epub 2017 Feb 27.

PMID:
28240987
27.

Baby hamster kidney cell-derived recombinant factor VIII: a quarter century of learning and clinical experience.

Afonja O, Kozak R, Petraro P, Michaels LA, Mathew P, Lemm G, Kessler C.

Expert Rev Hematol. 2016 Dec;9(12):1151-1164. Epub 2016 Nov 28. Review.

PMID:
27841041
28.

Structural defects in cubic semiconductors characterized by aberration-corrected scanning transmission electron microscopy.

Arroyo Rojas Dasilva Y, Kozak R, Erni R, Rossell MD.

Ultramicroscopy. 2017 May;176:11-22. doi: 10.1016/j.ultramic.2016.09.015. Epub 2016 Sep 28.

PMID:
27838069
29.

Molecular characterization of pathogenic and nonpathogenic fowl aviadenovirus serotype 11 isolates.

Slaine PD, Ackford JG, Kropinski AM, Kozak RA, Krell PJ, Nagy É.

Can J Microbiol. 2016 Dec;62(12):993-1002. Epub 2016 Jul 12.

PMID:
27781484
30.

Uterine Artery Embolization (UAE) for Uterine Arteriovenous Malformation (AVM) in 5 Women Desiring Fertility: Pregnancy Outcomes.

Vilos AG, Vilos GA, Hollett-Caines J, Oraif A, Garvin G, Kozak R.

J Minim Invasive Gynecol. 2015 Nov-Dec;22(6S):S234. doi: 10.1016/j.jmig.2015.08.825. Epub 2015 Oct 15. No abstract available.

PMID:
27679139
31.

Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques.

Wong G, Qiu X, de La Vega MA, Fernando L, Wei H, Bello A, Fausther-Bovendo H, Audet J, Kroeker A, Kozak R, Tran K, He S, Tierney K, Soule G, Moffat E, Günther S, Gao GF, Strong J, Embury-Hyatt C, Kobinger G.

J Infect Dis. 2016 Oct 15;214(suppl 3):S281-S289. Epub 2016 Sep 19.

32.

Variation of Human Salivary O-Glycome.

Kozak RP, Urbanowicz PA, Punyadeera C, Reiding KR, Jansen BC, Royle L, Spencer DI, Fernandes DL, Wuhrer M.

PLoS One. 2016 Sep 9;11(9):e0162824. doi: 10.1371/journal.pone.0162824. eCollection 2016.

33.

Nicotinic receptor subtypes differentially modulate glutamate release in the dorsal medial striatum.

Howe WM, Young DA, Bekheet G, Kozak R.

Neurochem Int. 2016 Nov;100:30-34. doi: 10.1016/j.neuint.2016.08.009. Epub 2016 Aug 26.

PMID:
27568861
34.

Ferrets Infected with Bundibugyo Virus or Ebola Virus Recapitulate Important Aspects of Human Filovirus Disease.

Kozak R, He S, Kroeker A, de La Vega MA, Audet J, Wong G, Urfano C, Antonation K, Embury-Hyatt C, Kobinger GP, Qiu X.

J Virol. 2016 Sep 29;90(20):9209-23. doi: 10.1128/JVI.01033-16. Print 2016 Oct 15.

35.

Automated High-Throughput Permethylation for Glycosylation Analysis of Biologics Using MALDI-TOF-MS.

Shubhakar A, Kozak RP, Reiding KR, Royle L, Spencer DI, Fernandes DL, Wuhrer M.

Anal Chem. 2016 Sep 6;88(17):8562-9. doi: 10.1021/acs.analchem.6b01639. Epub 2016 Aug 15.

PMID:
27479043
36.

Longitudinal monitoring of immunoglobulin A glycosylation during pregnancy by simultaneous MALDI-FTICR-MS analysis of N- and O-glycopeptides.

Bondt A, Nicolardi S, Jansen BC, Stavenhagen K, Blank D, Kammeijer GS, Kozak RP, Fernandes DL, Hensbergen PJ, Hazes JM, van der Burgt YE, Dolhain RJ, Wuhrer M.

Sci Rep. 2016 Jun 15;6:27955. doi: 10.1038/srep27955.

37.

Prophylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection.

Qiu X, Kroeker A, He S, Kozak R, Audet J, Mbikay M, Chrétien M.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5182-8. doi: 10.1128/AAC.00307-16. Print 2016 Sep.

38.

Vaccines against 'the other' Ebolavirus species.

Kozak RA, Kobinger GP.

Expert Rev Vaccines. 2016 Sep;15(9):1093-100. doi: 10.1586/14760584.2016.1170597. Epub 2016 Apr 12. Review.

PMID:
27010528
39.

Ebola viral load at diagnosis associates with patient outcome and outbreak evolution.

de La Vega MA, Caleo G, Audet J, Qiu X, Kozak RA, Brooks JI, Kern S, Wolz A, Sprecher A, Greig J, Lokuge K, Kargbo DK, Kargbo B, Di Caro A, Grolla A, Kobasa D, Strong JE, Ippolito G, Van Herp M, Kobinger GP.

J Clin Invest. 2015 Dec;125(12):4421-8. doi: 10.1172/JCI83162. Epub 2015 Nov 9.

40.

Characterization of a sialate-O-acetylesterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid release by NanH, its cognate sialidase.

Phansopa C, Kozak RP, Liew LP, Frey AM, Farmilo T, Parker JL, Kelly DJ, Emery RJ, Thomson RI, Royle L, Gardner RA, Spencer DI, Stafford GP.

Biochem J. 2015 Dec 1;472(2):157-67. doi: 10.1042/BJ20150388. Epub 2015 Sep 16.

41.

Characterization of a novel adenovirus isolated from a skunk.

Kozak RA, Ackford JG, Slaine P, Li A, Carman S, Campbell D, Welch MK, Kropinski AM, Nagy É.

Virology. 2015 Nov;485:16-24. doi: 10.1016/j.virol.2015.06.026. Epub 2015 Jul 17.

42.

Cross-site strain comparison of pharmacological deficits in the touchscreen visual discrimination test.

Mohler EG, Ding Z, Rueter LE, Chapin D, Young D, Kozak R.

Psychopharmacology (Berl). 2015 Nov;232(21-22):4033-41. doi: 10.1007/s00213-015-4012-0. Epub 2015 Jul 17.

PMID:
26177580
43.
44.

The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists.

Yohn SE, Santerre JL, Nunes EJ, Kozak R, Podurgiel SJ, Correa M, Salamone JD.

Pharmacol Biochem Behav. 2015 Aug;135:217-26. doi: 10.1016/j.pbb.2015.05.003. Epub 2015 May 29.

PMID:
26022661
45.

MAM (E17) rodent developmental model of neuropsychiatric disease: disruptions in learning and dysregulation of nucleus accumbens dopamine release, but spared executive function.

Howe WM, Tierney PL, Young DA, Oomen C, Kozak R.

Psychopharmacology (Berl). 2015 Nov;232(21-22):4113-27. doi: 10.1007/s00213-015-3955-5. Epub 2015 May 12.

PMID:
25963563
46.

Uterine artery embolization for uterine arteriovenous malformation in five women desiring fertility: pregnancy outcomes.

Vilos AG, Vilos GA, Hollett-Caines J, Rajakumar C, Garvin G, Kozak R.

Hum Reprod. 2015 Jul;30(7):1599-605. doi: 10.1093/humrep/dev097. Epub 2015 May 6.

PMID:
25954037
47.

Development of a Schistosoma mansoni shotgun O-glycan microarray and application to the discovery of new antigenic schistosome glycan motifs.

van Diepen A, van der Plas AJ, Kozak RP, Royle L, Dunne DW, Hokke CH.

Int J Parasitol. 2015 Jun;45(7):465-75. doi: 10.1016/j.ijpara.2015.02.008. Epub 2015 Mar 26.

48.

Next generation sequencing of the hepatitis C virus NS5B gene reveals potential novel S282 drug resistance mutations.

Ji H, Kozak RA, Biondi MJ, Pilon R, Vallee D, Liang BB, La D, Kim J, Van Domselaar G, Leonard L, Sandstrom P, Brooks J.

Virology. 2015 Mar;477:1-9. doi: 10.1016/j.virol.2014.12.037. Epub 2015 Jan 17.

49.

Post-uterine artery embolization pain and clinical outcomes for symptomatic myomas using gelfoam pledgets alone versus embospheres plus gelfoam pledgets: a comparative pilot study.

Vilos AG, Vilos GA, Hollett-Caines J, Garvin G, Kozak R, Abu-Rafea B.

J Obstet Gynaecol Can. 2014 Nov;36(11):983-989. doi: 10.1016/S1701-2163(15)30411-4.

PMID:
25574675
50.

Crystal structure of the ternary silicide Gd2Re3Si5.

Fedyna V, Kozak R, Gladyshevskii R.

Acta Crystallogr Sect E Struct Rep Online. 2014 Nov 8;70(Pt 12):469-70. doi: 10.1107/S1600536814024234. eCollection 2014 Dec 1.

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