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Items: 1 to 50 of 125

1.

Development of a cysteine-conjugatable disulfide FRET probe: Influence of Charge on Linker Cleavage and Payload Trafficking for an anti-HER2 antibody conjugate.

Scales S, Tsai SP, Zacharias N, Cruz-Chuh JD, Bullen G, Velasquez E, Chang J, Bruguera E, Kozak KR, Sadowsky J.

Bioconjug Chem. 2019 Nov 14. doi: 10.1021/acs.bioconjchem.9b00678. [Epub ahead of print]

PMID:
31726009
2.

Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer.

Boswell CA, Yadav DB, Mundo EE, Yu SF, Lacap JA, Fourie-O'Donohue A, Kozak KR, Ferl GZ, Zhang C, Ho J, Ulufatu S, Khawli LA, Lin K.

Oncotarget. 2019 Oct 22;10(58):6234-6244. doi: 10.18632/oncotarget.27263. eCollection 2019 Oct 22.

3.

Correction: An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer.

Bhakta S, Crocker LM, Chen Y, Hazen M, Schutten MM, Li D, Kuijl C, Ohri R, Zhong F, Poon KA, Go MAT, Cheng E, Piskol R, Firestein R, Fourie-O'Donohue A, Kozak KR, Raab H, Hongo JA, Sampath D, Dennis MS, Scheller RH, Polakis P, Junutula JR.

Mol Cancer Ther. 2019 Nov;18(11):2182. doi: 10.1158/1535-7163.MCT-19-0749. No abstract available.

PMID:
31676543
4.

Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity.

Pillow TH, Adhikari P, Blake RA, Chen J, Del Rosario G, Deshmukh G, Figueroa I, Gascoigne KE, Kamath AV, Kaufman S, Kleinheinz T, Kozak KR, Latifi B, Leipold DD, Sing Li C, Li R, Mulvihill MM, O'Donohue A, Rowntree RK, Sadowsky JD, Wai J, Wang X, Wu C, Xu Z, Yao H, Yu SF, Zhang D, Zang R, Zhang H, Zhou H, Zhu X, Dragovich PS.

ChemMedChem. 2019 Oct 31. doi: 10.1002/cmdc.201900497. [Epub ahead of print]

PMID:
31674143
5.

Evaluation and use of an anti-cynomolgus monkey CD79b surrogate antibody-drug conjugate to enable clinical development of polatuzumab vedotin.

Li D, Lee D, Dere RC, Zheng B, Yu SF, Fuh FK, Kozak KR, Chung S, Bumbaca Yadav D, Nazzal D, Danilenko D, Go MAT, Williams M, Polson AG, Poon KA, Prabhu S.

Br J Pharmacol. 2019 Oct;176(19):3805-3818. doi: 10.1111/bph.14784. Epub 2019 Aug 24.

6.

Catalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody-Drug Conjugates.

Zhang D, Fourie-O'Donohue A, Dragovich PS, Pillow TH, Sadowsky JD, Kozak KR, Cass RT, Liu L, Deng Y, Liu Y, Hop CECA, Khojasteh SC.

Drug Metab Dispos. 2019 Oct;47(10):1156-1163. doi: 10.1124/dmd.118.086132. Epub 2019 May 13.

PMID:
31085544
7.

Antibody-Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo.

Su D, Chen J, Cosino E, Dela Cruz-Chuh J, Davis H, Del Rosario G, Figueroa I, Goon L, He J, Kamath AV, Kaur S, Kozak KR, Lau J, Lee D, Lee MV, Leipold D, Liu L, Liu P, Lu GL, Nelson C, Ng C, Pillow TH, Polakis P, Polson AG, Rowntree RK, Saad O, Safina B, Stagg NJ, Tercel M, Vandlen R, Vollmar BS, Wai J, Wang T, Wei B, Xu K, Xue J, Xu Z, Yan G, Yao H, Yu SF, Zhang D, Zhong F, Dragovich PS.

Bioconjug Chem. 2019 May 15;30(5):1356-1370. doi: 10.1021/acs.bioconjchem.9b00133. Epub 2019 Apr 22.

PMID:
30966735
8.

Development, Optimization, and Structural Characterization of an Efficient Peptide-Based Photoaffinity Cross-Linking Reaction for Generation of Homogeneous Conjugates from Wild-Type Antibodies.

Vance N, Zacharias N, Ultsch M, Li G, Fourie A, Liu P, LaFrance-Vanasse J, Ernst JA, Sandoval W, Kozak KR, Phillips G, Wang W, Sadowsky J.

Bioconjug Chem. 2019 Jan 16;30(1):148-160. doi: 10.1021/acs.bioconjchem.8b00809. Epub 2019 Jan 7.

PMID:
30566343
9.

Preclinical pharmacokinetics and pharmacodynamics of DCLL9718A: An antibody-drug conjugate for the treatment of acute myeloid leukemia.

Leipold DD, Figueroa I, Masih S, Latifi B, Yip V, Shen BQ, Dere RC, Carrasco-Triguero M, Lee MV, Saad OM, Liu L, He J, Su D, Xu K, Vuillemenot BR, Laing ST, Schutten M, Kozak KR, Zheng B, Polson AG, Kamath AV.

MAbs. 2018 Nov-Dec;10(8):1312-1321. doi: 10.1080/19420862.2018.1517565. Epub 2018 Oct 2.

10.

Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates.

Pei Z, Chen C, Chen J, Cruz-Chuh JD, Delarosa R, Deng Y, Fourie-O'Donohue A, Figueroa I, Guo J, Jin W, Khojasteh SC, Kozak KR, Latifi B, Lee J, Li G, Lin E, Liu L, Lu J, Martin S, Ng C, Nguyen T, Ohri R, Lewis Phillips G, Pillow TH, Rowntree RK, Stagg NJ, Stokoe D, Ulufatu S, Verma VA, Wai J, Wang J, Xu K, Xu Z, Yao H, Yu SF, Zhang D, Dragovich PS.

Mol Pharm. 2018 Sep 4;15(9):3979-3996. doi: 10.1021/acs.molpharmaceut.8b00431. Epub 2018 Aug 6.

PMID:
30040421
11.

FRET Reagent Reveals the Intracellular Processing of Peptide-Linked Antibody-Drug Conjugates.

Lee BC, Chalouni C, Doll S, Nalle SC, Darwish M, Tsai SP, Kozak KR, Del-Rosario G, Yu SF, Erickson H, Vandlen R.

Bioconjug Chem. 2018 Jul 18;29(7):2468-2477. doi: 10.1021/acs.bioconjchem.8b00362. Epub 2018 Jun 13.

PMID:
29856915
12.

Automated On-tip Affinity Capture Coupled with Mass Spectrometry to Characterize Intact Antibody-Drug Conjugates from Blood.

Li KS, Chu PY, Fourie-O'Donohue A, Srikumar N, Kozak KR, Liu Y, Tran JC.

J Am Soc Mass Spectrom. 2018 Jul;29(7):1532-1537. doi: 10.1007/s13361-018-1961-7. Epub 2018 May 29.

PMID:
29845559
13.

Prediction of non-linear pharmacokinetics in humans of an antibody-drug conjugate (ADC) when evaluation of higher doses in animals is limited by tolerability: Case study with an anti-CD33 ADC.

Figueroa I, Leipold D, Leong S, Zheng B, Triguero-Carrasco M, Fourie-O'Donohue A, Kozak KR, Xu K, Schutten M, Wang H, Polson AG, Kamath AV.

MAbs. 2018 Jul;10(5):738-750. doi: 10.1080/19420862.2018.1465160. Epub 2018 May 18.

14.

Conjugation of Indoles to Antibodies through a Novel Self-Immolating Linker.

Dragovich PS, Blake RA, Chen C, Chen J, Chuh J, den Besten W, Fan F, Fourie A, Hartman SJ, He C, He J, Ingalla ER, Kozak KR, Leong SR, Lu J, Ma Y, Meng L, Nannini M, Oeh J, Ohri R, Lewis Phillips G, Pillow TH, Rowntree RK, Sampath D, Vandlen R, Vollmar B, Wai J, Wertz IE, Xu K, Xu Z, Zhang D.

Chemistry. 2018 Apr 3;24(19):4830-4834. doi: 10.1002/chem.201800859. Epub 2018 Mar 25.

PMID:
29493023
15.

Modulating Antibody-Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification.

Su D, Kozak KR, Sadowsky J, Yu SF, Fourie-O'Donohue A, Nelson C, Vandlen R, Ohri R, Liu L, Ng C, He J, Davis H, Lau J, Del Rosario G, Cosino E, Cruz-Chuh JD, Ma Y, Zhang D, Darwish M, Cai W, Chen C, Zhou H, Lu J, Liu Y, Kaur S, Xu K, Pillow TH.

Bioconjug Chem. 2018 Apr 18;29(4):1155-1167. doi: 10.1021/acs.bioconjchem.7b00785. Epub 2018 Mar 13.

PMID:
29481745
16.

High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based Linkers.

Ohri R, Bhakta S, Fourie-O'Donohue A, Dela Cruz-Chuh J, Tsai SP, Cook R, Wei B, Ng C, Wong AW, Bos AB, Farahi F, Bhakta J, Pillow TH, Raab H, Vandlen R, Polakis P, Liu Y, Erickson H, Junutula JR, Kozak KR.

Bioconjug Chem. 2018 Feb 21;29(2):473-485. doi: 10.1021/acs.bioconjchem.7b00791. Epub 2018 Feb 9.

PMID:
29425028
17.

Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody-Drug Conjugates with Phenol-Containing Payloads.

Zhang D, Le H, Cruz-Chuh JD, Bobba S, Guo J, Staben L, Zhang C, Ma Y, Kozak KR, Lewis Phillips GD, Vollmar BS, Sadowsky JD, Vandlen R, Wei B, Su D, Fan P, Dragovich PS, Khojasteh SC, Hop CECA, Pillow TH.

Bioconjug Chem. 2018 Feb 21;29(2):267-274. doi: 10.1021/acs.bioconjchem.7b00576. Epub 2018 Feb 7.

PMID:
29369629
18.

Intratumoral Payload Concentration Correlates with the Activity of Antibody-Drug Conjugates.

Zhang D, Yu SF, Khojasteh SC, Ma Y, Pillow TH, Sadowsky JD, Su D, Kozak KR, Xu K, Polson AG, Dragovich PS, Hop CECA.

Mol Cancer Ther. 2018 Mar;17(3):677-685. doi: 10.1158/1535-7163.MCT-17-0697. Epub 2018 Jan 18.

19.

An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer.

Bhakta S, Crocker LM, Chen Y, Hazen M, Schutten MM, Li D, Kuijl C, Ohri R, Zhong F, Poon KA, Go MAT, Cheng E, Piskol R, Firestein R, Fourie-O'Donohue A, Kozak KR, Raab H, Hongo JA, Sampath D, Dennis MS, Scheller RH, Polakis P, Junutula JR.

Mol Cancer Ther. 2018 Mar;17(3):638-649. doi: 10.1158/1535-7163.MCT-17-0813. Epub 2017 Dec 27. Erratum in: Mol Cancer Ther. 2019 Nov;18(11):2182.

20.

Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity.

Wei B, Gunzner-Toste J, Yao H, Wang T, Wang J, Xu Z, Chen J, Wai J, Nonomiya J, Tsai SP, Chuh J, Kozak KR, Liu Y, Yu SF, Lau J, Li G, Phillips GD, Leipold D, Kamath A, Su D, Xu K, Eigenbrot C, Steinbacher S, Ohri R, Raab H, Staben LR, Zhao G, Flygare JA, Pillow TH, Verma V, Masterson LA, Howard PW, Safina B.

J Med Chem. 2018 Feb 8;61(3):989-1000. doi: 10.1021/acs.jmedchem.7b01430. Epub 2017 Dec 21.

PMID:
29227683
21.

Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers.

Gregson SJ, Masterson LA, Wei B, Pillow TH, Spencer SD, Kang GD, Yu SF, Raab H, Lau J, Li G, Lewis Phillips GD, Gunzner-Toste J, Safina BS, Ohri R, Darwish M, Kozak KR, Dela Cruz-Chuh J, Polson A, Flygare JA, Howard PW.

J Med Chem. 2017 Dec 14;60(23):9490-9507. doi: 10.1021/acs.jmedchem.7b00736. Epub 2017 Nov 16.

PMID:
29112410
22.

Stabilizing a Tubulysin Antibody-Drug Conjugate To Enable Activity Against Multidrug-Resistant Tumors.

Staben LR, Yu SF, Chen J, Yan G, Xu Z, Del Rosario G, Lau JT, Liu L, Guo J, Zheng B, Cruz-Chuh JD, Lee BC, Ohri R, Cai W, Zhou H, Kozak KR, Xu K, Lewis Phillips GD, Lu J, Wai J, Polson AG, Pillow TH.

ACS Med Chem Lett. 2017 Sep 5;8(10):1037-1041. doi: 10.1021/acsmedchemlett.7b00243. eCollection 2017 Oct 12.

23.

Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody-Drug Conjugates.

Caculitan NG, Dela Cruz Chuh J, Ma Y, Zhang D, Kozak KR, Liu Y, Pillow TH, Sadowsky J, Cheung TK, Phung Q, Haley B, Lee BC, Akita RW, Sliwkowski MX, Polson AG.

Cancer Res. 2017 Dec 15;77(24):7027-7037. doi: 10.1158/0008-5472.CAN-17-2391. Epub 2017 Oct 18.

24.

Attachment Site Cysteine Thiol pKa Is a Key Driver for Site-Dependent Stability of THIOMAB Antibody-Drug Conjugates.

Vollmar BS, Wei B, Ohri R, Zhou J, He J, Yu SF, Leipold D, Cosino E, Yee S, Fourie-O'Donohue A, Li G, Phillips GL, Kozak KR, Kamath A, Xu K, Lee G, Lazar GA, Erickson HK.

Bioconjug Chem. 2017 Oct 18;28(10):2538-2548. doi: 10.1021/acs.bioconjchem.7b00365. Epub 2017 Sep 22.

PMID:
28885827
25.

Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein- and Peptide-Payload Conjugates: Application to THIOMAB Antibody-Drug Conjugates.

Sadowsky JD, Pillow TH, Chen J, Fan F, He C, Wang Y, Yan G, Yao H, Xu Z, Martin S, Zhang D, Chu P, Dela Cruz-Chuh J, O'Donohue A, Li G, Del Rosario G, He J, Liu L, Ng C, Su D, Lewis Phillips GD, Kozak KR, Yu SF, Xu K, Leipold D, Wai J.

Bioconjug Chem. 2017 Aug 16;28(8):2086-2098. doi: 10.1021/acs.bioconjchem.7b00258. Epub 2017 Jul 13.

PMID:
28636382
26.

Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates.

Pillow TH, Sadowsky JD, Zhang D, Yu SF, Del Rosario G, Xu K, He J, Bhakta S, Ohri R, Kozak KR, Ha E, Junutula JR, Flygare JA.

Chem Sci. 2017 Jan 1;8(1):366-370. doi: 10.1039/c6sc01831a. Epub 2016 Aug 22.

27.

Linker Immolation Determines Cell Killing Activity of Disulfide-Linked Pyrrolobenzodiazepine Antibody-Drug Conjugates.

Zhang D, Pillow TH, Ma Y, Cruz-Chuh JD, Kozak KR, Sadowsky JD, Lewis Phillips GD, Guo J, Darwish M, Fan P, Chen J, He C, Wang T, Yao H, Xu Z, Chen J, Wai J, Pei Z, Hop CE, Khojasteh SC, Dragovich PS.

ACS Med Chem Lett. 2016 Aug 26;7(11):988-993. eCollection 2016 Nov 10.

28.

Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates.

Staben LR, Koenig SG, Lehar SM, Vandlen R, Zhang D, Chuh J, Yu SF, Ng C, Guo J, Liu Y, Fourie-O'Donohue A, Go M, Linghu X, Segraves NL, Wang T, Chen J, Wei B, Phillips GD, Xu K, Kozak KR, Mariathasan S, Flygare JA, Pillow TH.

Nat Chem. 2016 Dec;8(12):1112-1119. doi: 10.1038/nchem.2635. Epub 2016 Oct 17.

PMID:
27874860
29.

Injectable (-)-gossypol-loaded Pluronic P85 micelles for cancer chemoradiotherapy.

Tomoda K, Chiang HC, Kozak KR, Kwon GS.

Int J Radiat Biol. 2017 Apr;93(4):402-406. doi: 10.1080/09553002.2016.1257833. Epub 2016 Dec 9.

30.

Triolimus: A Multi-Drug Loaded Polymeric Micelle Containing Paclitaxel, 17-AAG, and Rapamycin as a Novel Radiosensitizer.

Tomoda K, Tam YT, Cho H, Buehler D, Kozak KR, Kwon GS.

Macromol Biosci. 2017 Jan;17(1). doi: 10.1002/mabi.201600194. Epub 2016 Jul 1.

31.

Identification of Patients Who Benefit From Bevacizumab in High-Grade Glioma-An Easy Question Turned Difficult: Treat the Scan or the Patient?

Kruser TJ, Mehta MP, Kozak KR.

J Clin Oncol. 2016 Apr 10;34(11):1281-2. doi: 10.1200/JCO.2015.64.7883. Epub 2016 Feb 16. No abstract available.

PMID:
26884565
32.

Impact of a Contralateral Tumor Nodule on Survival in Non-Small-Cell Lung Cancer.

Morris ZS, Cannon DM, Morris BA, Bentzen SM, Kozak KR.

J Thorac Oncol. 2015 Nov;10(11):1608-15. doi: 10.1097/JTO.0000000000000655.

33.

Clinical Activity of Pazopanib in Metastatic Extraosseous Ewing Sarcoma.

Attia S, Okuno SH, Robinson SI, Webber NP, Indelicato DJ, Jones RL, Bagaria SP, Jones RL, Sherman C, Kozak KR, Cortese CM, McFarland T, Trent JC, Maki RG.

Rare Tumors. 2015 May 21;7(2):5992. doi: 10.4081/rt.2015.5992. eCollection 2015 May 5.

34.

Examination of Gossypol-Pluronic Micelles as Potential Radiosensitizers.

Tomoda K, Chiang C, Kozak KR, Kwon GS.

AAPS J. 2015 Nov;17(6):1369-75. doi: 10.1208/s12248-015-9809-6. Epub 2015 Aug 6.

35.

Statin use in cancer patients with brain metastases: a missed communication opportunity at the end of life.

Mullvain JA, Kozak KR, Moody JS, Campbell TC.

Support Care Cancer. 2015 Sep;23(9):2643-8. doi: 10.1007/s00520-015-2624-x. Epub 2015 Feb 7.

PMID:
25663509
36.

Cardiac and inflammatory biomarkers do not correlate with volume of heart or lung receiving radiation.

Kuo AH, Ancukiewicz M, Kozak KR, Yock TI, Padera TP.

Radiat Oncol. 2015 Jan 9;10:5. doi: 10.1186/s13014-014-0324-1.

37.

Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for THIOMAB™ Drug Conjugates.

Sukumaran S, Gadkar K, Zhang C, Bhakta S, Liu L, Xu K, Raab H, Yu SF, Mai E, Fourie-O'Donohue A, Kozak KR, Ramanujan S, Junutula JR, Lin K.

Pharm Res. 2015 Jun;32(6):1884-93. doi: 10.1007/s11095-014-1582-1. Epub 2014 Dec 2.

PMID:
25446772
38.

Choroid plexus tumor epidemiology and outcomes: implications for surgical and radiotherapeutic management.

Cannon DM, Mohindra P, Gondi V, Kruser TJ, Kozak KR.

J Neurooncol. 2015 Jan;121(1):151-7. doi: 10.1007/s11060-014-1616-x. Epub 2014 Oct 1.

PMID:
25270349
39.

An antimesothelin-monomethyl auristatin e conjugate with potent antitumor activity in ovarian, pancreatic, and mesothelioma models.

Scales SJ, Gupta N, Pacheco G, Firestein R, French DM, Koeppen H, Rangell L, Barry-Hamilton V, Luis E, Chuh J, Zhang Y, Ingle GS, Fourie-O'Donohue A, Kozak KR, Ross S, Dennis MS, Spencer SD.

Mol Cancer Ther. 2014 Nov;13(11):2630-40. doi: 10.1158/1535-7163.MCT-14-0487-T. Epub 2014 Sep 23.

40.

Delivery of definitive dose external beam radiation in close proximity to an implanted deep brain stimulator.

Borkenhagen JF, Morris ZS, Hoberg JR, Kozak KR, Shapiro LQ.

Pract Radiat Oncol. 2014 Sep-Oct;4(5):294-297. doi: 10.1016/j.prro.2013.10.003. Epub 2013 Nov 21. No abstract available.

PMID:
25194097
41.

Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering.

Pillow TH, Tien J, Parsons-Reponte KL, Bhakta S, Li H, Staben LR, Li G, Chuh J, Fourie-O'Donohue A, Darwish M, Yip V, Liu L, Leipold DD, Su D, Wu E, Spencer SD, Shen BQ, Xu K, Kozak KR, Raab H, Vandlen R, Lewis Phillips GD, Scheller RH, Polakis P, Sliwkowski MX, Flygare JA, Junutula JR.

J Med Chem. 2014 Oct 9;57(19):7890-9. doi: 10.1021/jm500552c. Epub 2014 Sep 18.

PMID:
25191794
42.

Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summary.

Wallner PE, Anscher MS, Barker CA, Bassetti M, Bristow RG, Cha YI, Dicker AP, Formenti SC, Graves EE, Hahn SM, Hei TK, Kimmelman AC, Kirsch DG, Kozak KR, Lawrence TS, Marples B, McBride WH, Mikkelsen RB, Park CC, Weidhaas JB, Zietman AL, Steinberg M.

Int J Radiat Oncol Biol Phys. 2014 Jan 1;88(1):11-7. doi: 10.1016/j.ijrobp.2013.09.040. Epub 2013 Nov 15. Erratum in: Int J Radiat Oncol Biol Phys. 2015 Apr 1;91(5):1115.

PMID:
24246724
43.

Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells.

Kesler CT, Kuo AH, Wong HK, Masuck DJ, Shah JL, Kozak KR, Held KD, Padera TP.

Angiogenesis. 2014 Apr;17(2):419-27. doi: 10.1007/s10456-013-9400-7. Epub 2013 Nov 8.

44.

The role of radiation in retroperitoneal sarcomas.

Mohindra P, Neuman HB, Kozak KR.

Curr Treat Options Oncol. 2013 Sep;14(3):425-41. doi: 10.1007/s11864-013-0236-6.

45.

DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma.

Li D, Poon KA, Yu SF, Dere R, Go M, Lau J, Zheng B, Elkins K, Danilenko D, Kozak KR, Chan P, Chuh J, Shi X, Nazzal D, Fuh F, McBride J, Ramakrishnan V, de Tute R, Rawstron A, Jack AS, Deng R, Chu YW, Dornan D, Williams M, Ho W, Ebens A, Prabhu S, Polson AG.

Mol Cancer Ther. 2013 Jul;12(7):1255-65. doi: 10.1158/1535-7163.MCT-12-1173. Epub 2013 Apr 18.

46.

Total antibody quantification for MMAE-conjugated antibody-drug conjugates: impact of assay format and reagents.

Kozak KR, Tsai SP, Fourie-O'Donohue A, dela Cruz Chuh J, Roth L, Cook R, Chan E, Chan P, Darwish M, Ohri R, Raab H, Zhang C, Lin K, Wong WL.

Bioconjug Chem. 2013 May 15;24(5):772-9. doi: 10.1021/bc300491k. Epub 2013 Apr 11.

PMID:
23578050
47.

Expression of angiopoietin-TIE system components in angiosarcoma.

Buehler D, Rush P, Hasenstein JR, Rice SR, Hafez GR, Longley BJ, Kozak KR.

Mod Pathol. 2013 Aug;26(8):1032-40. doi: 10.1038/modpathol.2013.43. Epub 2013 Apr 5.

48.

Acute hematologic and mucosal toxicities in head and neck cancer patients undergoing chemoradiotherapy: a comparison of 3D-CRT, IMRT, and helical tomotherapy.

Kruser TJ, Rice SR, Cleary KP, Geye HM, Tome WA, Harari PM, Kozak KR.

Technol Cancer Res Treat. 2013 Oct;12(5):383-9. doi: 10.7785/tcrt.2012.500332. Epub 2013 Mar 26.

49.

Agreement among RTOG sarcoma radiation oncologists in contouring suspicious peritumoral edema for preoperative radiation therapy of soft tissue sarcoma of the extremity.

Bahig H, Roberge D, Bosch W, Levin W, Petersen I, Haddock M, Freeman C, Delaney TF, Abrams RA, Indelicato DJ, Baldini EH, Hitchcock Y, Kirsch DG, Kozak KR, Wolfson A, Wang D.

Int J Radiat Oncol Biol Phys. 2013 Jun 1;86(2):298-303. doi: 10.1016/j.ijrobp.2013.01.032. Epub 2013 Mar 6.

50.

Angiosarcoma outcomes and prognostic factors: a 25-year single institution experience.

Buehler D, Rice SR, Moody JS, Rush P, Hafez GR, Attia S, Longley BJ, Kozak KR.

Am J Clin Oncol. 2014 Oct;37(5):473-9. doi: 10.1097/COC.0b013e31827e4e7b.

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