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Items: 1 to 50 of 450

1.

Density functional analysis: The theory of density-corrected DFT.

Vuckovic S, Song S, Kozlowski J, Sim E, Burke K.

J Chem Theory Comput. 2019 Nov 4. doi: 10.1021/acs.jctc.9b00826. [Epub ahead of print]

PMID:
31682433
2.

Erratum for Manoharan et al., "Metagenomes from Coastal Marine Sediments Give Insights into the Ecological Role and Cellular Features of Loki- and Thorarchaeota".

Manoharan L, Kozlowski JA, Murdoch RW, Löffler FE, Sousa FL, Schleper C.

MBio. 2019 Oct 29;10(5). pii: e02509-19. doi: 10.1128/mBio.02509-19. No abstract available.

3.

Metagenomes from Coastal Marine Sediments Give Insights into the Ecological Role and Cellular Features of Loki- and Thorarchaeota.

Manoharan L, Kozlowski JA, Murdoch RW, Löffler FE, Sousa FL, Schleper C.

MBio. 2019 Sep 10;10(5). pii: e02039-19. doi: 10.1128/mBio.02039-19. Erratum in: MBio. 2019 Oct 29;10(5):.

4.
5.

Vanishing benefits - The loss of actinobacterial symbionts at elevated temperatures.

Horváthová T, Babik W, Kozłowski J, Bauchinger U.

J Therm Biol. 2019 May;82:222-228. doi: 10.1016/j.jtherbio.2019.04.015. Epub 2019 May 3.

PMID:
31128651
6.

Association of Adding Aspirin to Warfarin Therapy Without an Apparent Indication With Bleeding and Other Adverse Events.

Schaefer JK, Li Y, Gu X, Souphis NM, Haymart B, Kline-Rogers E, Almany SL, Kaatz S, Kozlowski JH, Krol GD, Sood SL, Froehlich JB, Barnes GD.

JAMA Intern Med. 2019 Apr 1;179(4):533-541. doi: 10.1001/jamainternmed.2018.7816.

PMID:
30830172
7.

Accurate Quantification of Residual Cancer Cells in Pelvic Washing Reveals Association with Cancer Recurrence Following Robot-Assisted Radical Cystectomy.

Wei L, Hussein AA, Ma Y, Azabdaftari G, Ahmed Y, Wong LP, Hu Q, Luo W, Cranwell VN, Bunch BL, Kozlowski JD, Singh PK, Glenn ST, Smith G, Johnson CS, Liu S, Guru KA.

J Urol. 2019 Jun;201(6):1105-1114. doi: 10.1097/JU.0000000000000142.

8.

Discovery of novel pan-genotypic HCV NS5A inhibitors containing a novel tetracyclic core.

Yu W, Hu B, Zhong B, Hao J, Lei Z, Agrawal S, Rokosz L, Liu R, Chen S, Asante-Appiah E, Kozlowski JA.

Bioorg Med Chem Lett. 2019 Mar 1;29(5):700-706. doi: 10.1016/j.bmcl.2019.01.031. Epub 2019 Jan 25.

PMID:
30711390
9.

Building a Culture of Health and Well-Being at Merck.

Gunther CE, Peddicord V, Kozlowski J, Li Y, Menture D, Fabius R, Frazee SG, Nigro PJ.

Popul Health Manag. 2019 Oct;22(5):449-456. doi: 10.1089/pop.2018.0116. Epub 2018 Dec 20.

10.

Extrinsic Mortality Can Shape Life-History Traits, Including Senescence.

Dańko MJ, Burger O, Argasiński K, Kozłowski J.

Evol Biol. 2018;45(4):395-404. doi: 10.1007/s11692-018-9458-7. Epub 2018 Jun 13.

11.

In Vitro Antiviral Profile of Ruzasvir, a Potent and Pangenotype Inhibitor of Hepatitis C Virus NS5A.

Asante-Appiah E, Liu R, Curry S, McMonagle P, Agrawal S, Carr D, Rokosz L, Lahser F, Bystol K, Chase R, Black S, Ferrari E, Ingravallo P, Tong L, Yu W, Kozlowski J.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01280-18. doi: 10.1128/AAC.01280-18. Print 2018 Nov.

12.

Periprocedural Bridging Anticoagulation: Measuring the Impact of a Clinical Trial on Care Delivery.

Barnes GD, Li Y, Gu X, Haymart B, Kline-Rogers E, Almany S, Kozlowski J, Krol G, McNamara M, Froehlich JB, Kaatz S.

Am J Med. 2019 Jan;132(1):109.e1-109.e7. doi: 10.1016/j.amjmed.2018.07.027. Epub 2018 Aug 1.

PMID:
30076828
13.

Use of Robotic Anastomosis Competency Evaluation (RACE) for assessment of surgical competency during urethrovesical anastomosis.

Khan H, Kozlowski JD, Hussein AA, Sharif M, Ahmed Y, May P, Hammond Y, Stone K, Ahmad B, Cole A, Hasasneh A, Raheem S, Guru KA.

Can Urol Assoc J. 2018 Jul 24. doi: 10.5489/cuaj.5348. [Epub ahead of print]

14.

Warfarin for prevention of thromboembolism in atrial fibrillation: comparison of patient characteristics and outcomes of the "Real-World" Michigan Anticoagulation Quality Improvement Initiative (MAQI2) registry to the RE-LY, ROCKET-AF, and ARISTOTLE trials.

Hughey AB, Gu X, Haymart B, Kline-Rogers E, Almany S, Kozlowski J, Besley D, Krol GD, Ahsan S, Kaatz S, Froehlich JB, Barnes GD.

J Thromb Thrombolysis. 2018 Oct;46(3):316-324. doi: 10.1007/s11239-018-1698-y.

PMID:
29948756
15.

Sustained stimulation of β2- and β3-adrenergic receptors leads to persistent functional pain and neuroinflammation.

Zhang X, Hartung JE, Bortsov AV, Kim S, O'Buckley SC, Kozlowski J, Nackley AG.

Brain Behav Immun. 2018 Oct;73:520-532. doi: 10.1016/j.bbi.2018.06.017. Epub 2018 Jun 20.

16.

Comparative Proteomics of Three Species of Ammonia-Oxidizing Bacteria.

Zorz JK, Kozlowski JA, Stein LY, Strous M, Kleiner M.

Front Microbiol. 2018 May 14;9:938. doi: 10.3389/fmicb.2018.00938. eCollection 2018.

17.

Robot-Assisted Radical Cystectomy in Men: Technique of Spaces.

Ahmed YE, Hussein AA, Kozlowski J, Guru KA.

J Endourol. 2018 May;32(S1):S44-S48. doi: 10.1089/end.2017.0719.

PMID:
29774811
18.

Extended International Normalized Ratio testing intervals for warfarin-treated patients.

Barnes GD, Kong X, Cole D, Haymart B, Kline-Rogers E, Almany S, Dahu M, Ekola M, Kaatz S, Kozlowski J, Froehlich JB.

J Thromb Haemost. 2018 Jul;16(7):1307-1312. doi: 10.1111/jth.14150. Epub 2018 Jun 6.

19.

Discovery of MK-6169, a Potent Pan-Genotype Hepatitis C Virus NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Substitutions.

Yu W, Tong L, Selyutin O, Chen L, Hu B, Zhong B, Hao J, Ji T, Zan S, Yin J, Ruck RT, Curry S, McMonagle P, Agrawal S, Rokosz L, Carr D, Ingravallo P, Bystol K, Lahser F, Liu R, Chen S, Feng KI, Cartwright M, Asante-Appiah E, Kozlowski JA.

J Med Chem. 2018 May 10;61(9):3984-4003. doi: 10.1021/acs.jmedchem.7b01927. Epub 2018 May 1.

PMID:
29681153
20.

MK-8325: A silyl proline-containing NS5A inhibitor with pan-genotype activity for treatment of HCV.

Nair AG, Zeng Q, Selyutin O, Rosenblum SB, Jiang Y, Yang DY, Keertikar K, Zhou G, Dwyer M, Kim SH, Shankar B, Yu W, Tong L, Chen L, Mazzola R, Caldwell J, Tang H, Agrawal S, Liu R, Kong R, Ingravallo P, Xia E, Zhai Y, Nomeir A, Asante-Appiah E, Kozlowski JA.

Bioorg Med Chem Lett. 2018 Jun 1;28(10):1954-1957. doi: 10.1016/j.bmcl.2018.03.049. Epub 2018 Mar 20.

PMID:
29653894
21.

Concerted evolution of body mass and cell size: similar patterns among species of birds (Galliformes) and mammals (Rodentia).

Czarnoleski M, Labecka AM, Dragosz-Kluska D, Pis T, Pawlik K, Kapustka F, Kilarski WM, Kozłowski J.

Biol Open. 2018 Apr 9;7(4). pii: bio029603. doi: 10.1242/bio.029603.

22.

Are gestures worth a thousand words? Verbal and nonverbal communication during robot-assisted surgery.

Tiferes J, Hussein AA, Bisantz A, Higginbotham DJ, Sharif M, Kozlowski J, Ahmad B, O'Hara R, Wawrzyniak N, Guru K.

Appl Ergon. 2019 Jul;78:251-262. doi: 10.1016/j.apergo.2018.02.015. Epub 2018 Mar 7.

PMID:
29525267
23.

Sociodemographic factors in patients continuing warfarin vs those transitioning to direct oral anticoagulants.

Schaefer JK, Sood SL, Haymart B, Gu X, Kong X, Kline-Rogers E, Almany S, Kozlowski J, Krol GD, Kaatz S, Froehlich JB, Barnes GD.

Blood Adv. 2017 Dec 7;1(26):2536-2540. doi: 10.1182/bloodadvances.2017012377. eCollection 2017 Dec 12.

24.

Density-dependence interacts with extrinsic mortality in shaping life histories.

Dańko MJ, Burger O, Kozłowski J.

PLoS One. 2017 Oct 19;12(10):e0186661. doi: 10.1371/journal.pone.0186661. eCollection 2017.

25.

Effects of fat and exoskeletal mass on the mass scaling of metabolism in Carabidae beetles.

Schramm BW, Gudowska A, Antoł A, Labecka AM, Bauchinger U, Kozłowski J, Czarnoleski M.

J Insect Physiol. 2018 Apr;106(Pt 3):232-238. doi: 10.1016/j.jinsphys.2017.10.002. Epub 2017 Oct 13.

PMID:
29032157
26.

Mass scaling of metabolic rates in carabid beetles (Carabidae) - the importance of phylogeny, regression models and gas exchange patterns.

Gudowska A, Schramm BW, Czarnoleski M, Antoł A, Bauchinger U, Kozłowski J.

J Exp Biol. 2017 Sep 15;220(Pt 18):3363-3371. doi: 10.1242/jeb.159293. Epub 2017 Jul 19.

27.

Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis.

Boga SB, Alhassan AB, Liu J, Guiadeen D, Krikorian A, Gao X, Wang J, Yu Y, Anand R, Liu S, Yang C, Wu H, Cai J, Zhu H, Desai J, Maloney K, Gao YD, Fischmann TO, Presland J, Mansueto M, Xu Z, Leccese E, Knemeyer I, Garlisi CG, Bays N, Stivers P, Brandish PE, Hicks A, Cooper A, Kim RM, Kozlowski JA.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3939-3943. doi: 10.1016/j.bmcl.2017.03.040. Epub 2017 Mar 18.

PMID:
28720503
28.

Development of a prodrug of hydantoin based TACE inhibitor.

Tong L, Kim SH, Chen L, Kosinski A, Shankar BB, Girijavallabhan V, Yang DY, Yu W, Zhou G, Shih NY, Chen S, Hu M, Lundell D, Niu X, Umland S, Kozlowski JA.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3704-3708. doi: 10.1016/j.bmcl.2017.07.007. Epub 2017 Jul 3.

PMID:
28711352
29.

Barriers and facilitators to reducing frequent laboratory testing for patients who are stable on warfarin: a mixed methods study of de-implementation in five anticoagulation clinics.

Barnes GD, Misirliyan S, Kaatz S, Jackson EA, Haymart B, Kline-Rogers E, Kozlowski J, Krol G, Froehlich JB, Sales A.

Implement Sci. 2017 Jul 14;12(1):87. doi: 10.1186/s13012-017-0620-x.

30.

Physical mechanism or evolutionary trade-off? Factors dictating the relationship between metabolic rate and ambient temperature in carabid beetles.

Gudowska A, Schramm BW, Czarnoleski M, Kozłowski J, Bauchinger U.

J Therm Biol. 2017 Aug;68(Pt A):89-95. doi: 10.1016/j.jtherbio.2016.11.009. Epub 2016 Nov 13.

PMID:
28689726
31.

Not all cells are equal: effects of temperature and sex on the size of different cell types in the Madagascar ground gecko Paroedura picta.

Czarnoleski M, Labecka AM, Starostová Z, Sikorska A, Bonda-Ostaszewska E, Woch K, Kubička L, Kratochvíl L, Kozlowski J.

Biol Open. 2017 Aug 15;6(8):1149-1154. doi: 10.1242/bio.025817.

32.

Improving Teamwork: Evaluating Workload of Surgical Team During Robot-assisted Surgery.

Cavuoto LA, Hussein AA, Vasan V, Ahmed Y, Durrani A, Khan S, Cole A, Wang D, Kozlowski J, Ahmad B, Guru KA.

Urology. 2017 Sep;107:120-125. doi: 10.1016/j.urology.2017.05.012. Epub 2017 Jun 1.

PMID:
28579070
33.

Fused bi-heteroaryl substituted hydantoin compounds as TACE inhibitors.

Tong L, Kim SH, Rosner K, Yu W, Shankar BB, Chen L, Li D, Dai C, Girijavallabhan V, Popovici-Muller J, Yang L, Zhou G, Kosinski A, Siddiqui MA, Shih NY, Guo Z, Orth P, Chen S, Lundell D, Niu X, Umland S, Kozlowski JA.

Bioorg Med Chem Lett. 2017 Jul 15;27(14):3037-3042. doi: 10.1016/j.bmcl.2017.05.062. Epub 2017 May 22.

PMID:
28558971
34.

Complete Genome Sequence of Nitrosomonas cryotolerans ATCC 49181, a Phylogenetically Distinct Ammonia-Oxidizing Bacterium Isolated from Arctic Waters.

Rice MC, Norton JM, Stein LY, Kozlowski J, Bollmann A, Klotz MG, Sayavedra-Soto L, Shapiro N, Goodwin LA, Huntemann M, Clum A, Pillay M, Varghese N, Mikhailova N, Palaniappan K, Ivanova N, Mukherjee S, Reddy TB, Yee Ngan C, Daum C, Kyrpides N, Woyke T.

Genome Announc. 2017 Mar 16;5(11). pii: e00011-17. doi: 10.1128/genomeA.00011-17.

35.

Discovery of novel BTK inhibitors with carboxylic acids.

Gao X, Wang J, Liu J, Guiadeen D, Krikorian A, Boga SB, Alhassan AB, Selyutin O, Yu W, Yu Y, Anand R, Liu S, Yang C, Wu H, Cai J, Cooper A, Zhu H, Maloney K, Gao YD, Fischmann TO, Presland J, Mansueto M, Xu Z, Leccese E, Zhang-Hoover J, Knemeyer I, Garlisi CG, Bays N, Stivers P, Brandish PE, Hicks A, Kim R, Kozlowski JA.

Bioorg Med Chem Lett. 2017 Mar 15;27(6):1471-1477. doi: 10.1016/j.bmcl.2016.11.079. Epub 2016 Nov 25.

PMID:
28254166
36.

An evolutionary solution of terrestrial isopods to cope with low atmospheric oxygen levels.

Horváthová T, Antoł A, Czarnoleski M, Kozłowski J, Bauchinger U.

J Exp Biol. 2017 May 1;220(Pt 9):1563-1567. doi: 10.1242/jeb.156661. Epub 2017 Feb 22.

37.

Robot-assisted approach to 'W'-configuration urinary diversion: a step-by-step technique.

Hussein AA, Ahmed YE, Kozlowski JD, May PR, Nyquist J, Sexton S, Curtin L, Peabody JO, Abol-Enein H, Guru KA.

BJU Int. 2017 Jul;120(1):152-157. doi: 10.1111/bju.13824. Epub 2017 Mar 22.

38.

SAMe-TT2R2 predicts quality of anticoagulation in patients with acute venous thromboembolism: The MAQI2 experience.

Kataruka A, Kong X, Haymart B, Kline-Rogers E, Almany S, Kozlowski J, Krol GD, Kaatz S, McNamara MW, Froehlich JB, Barnes GD.

Vasc Med. 2017 Jun;22(3):197-203. doi: 10.1177/1358863X16682863. Epub 2017 Feb 1.

39.

Discontinuation of Warfarin Therapy for Patients With Atrial Fibrillation: The Michigan Anticoagulation Quality Improvement Initiative Experience.

Barnes GD, Kaatz S, Lopez A, Gu X, Kozlowski J, Krol GD, Froehlich JB.

JAMA Cardiol. 2017 Mar 1;2(3):341-343. doi: 10.1001/jamacardio.2016.5041. No abstract available.

PMID:
28052153
40.

Development, validation and clinical application of Pelvic Lymphadenectomy Assessment and Completion Evaluation: intraoperative assessment of lymph node dissection after robot-assisted radical cystectomy for bladder cancer.

Hussein AA, Hinata N, Dibaj S, May PR, Kozlowski JD, Abol-Enein H, Abaza R, Eun D, Khan MS, Mohler JL, Agarwal P, Pohar K, Sarle R, Boris R, Mane SS, Hutson A, Guru KA.

BJU Int. 2017 Jun;119(6):879-884. doi: 10.1111/bju.13748. Epub 2017 Jan 18.

41.

Prescribing trends of atrial fibrillation patients who switched from warfarin to a direct oral anticoagulant.

Hale ZD, Kong X, Haymart B, Gu X, Kline-Rogers E, Almany S, Kozlowski J, Krol GD, Kaatz S, Froehlich JB, Barnes GD.

J Thromb Thrombolysis. 2017 Feb;43(2):283-288. doi: 10.1007/s11239-016-1452-2.

PMID:
27837309
42.

Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms.

Tong L, Yu W, Chen L, Selyutin O, Dwyer MP, Nair AG, Mazzola R, Kim JH, Sha D, Yin J, Ruck RT, Davies IW, Hu B, Zhong B, Hao J, Ji T, Zan S, Liu R, Agrawal S, Xia E, Curry S, McMonagle P, Bystol K, Lahser F, Carr D, Rokosz L, Ingravallo P, Chen S, Feng KI, Cartwright M, Asante-Appiah E, Kozlowski JA.

J Med Chem. 2017 Jan 12;60(1):290-306. doi: 10.1021/acs.jmedchem.6b01310. Epub 2016 Nov 15.

43.

Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants.

Yu W, Tong L, Hu B, Zhong B, Hao J, Ji T, Zan S, Coburn CA, Selyutin O, Chen L, Rokosz L, Agrawal S, Liu R, Curry S, McMonagle P, Ingravallo P, Asante-Appiah E, Chen S, Kozlowski JA.

J Med Chem. 2016 Nov 23;59(22):10228-10243. Epub 2016 Nov 9.

PMID:
27792320
44.

Structure-activity relationships of proline modifications around the tetracyclic-indole class of NS5A inhibitors.

Tong L, Yu W, Coburn CA, Chen L, Selyutin O, Zeng Q, Dwyer MP, Nair AG, Shankar BB, Kim SH, Yang DY, Rosenblum SB, Ruck RT, Davies IW, Hu B, Zhong B, Hao J, Ji T, Zan S, Liu R, Agrawal S, Carr D, Curry S, McMonagle P, Bystol K, Lahser F, Ingravallo P, Chen S, Asante-Appiah E, Kozlowski JA.

Bioorg Med Chem Lett. 2016 Nov 1;26(21):5354-5360. doi: 10.1016/j.bmcl.2016.08.097. Epub 2016 Sep 2.

PMID:
27680588
45.

Alternative core development around the tetracyclic indole class of HCV NS5A inhibitors.

Tong L, Yu W, Coburn CA, Meinke PT, Nair AG, Dwyer MP, Chen L, Selyutin O, Rosenblum SB, Jiang Y, Fells J, Hu B, Zhong B, Soll RM, Liu R, Agrawal S, Xia E, Zhai Y, Kong R, Ingravallo P, Nomeir A, Asante-Appiah E, Kozlowski JA.

Bioorg Med Chem Lett. 2016 Oct 15;26(20):5132-5137. doi: 10.1016/j.bmcl.2016.07.057. Epub 2016 Jul 25.

46.

Substituted tetracyclic indole core derivatives of HCV NS5A inhibitor MK-8742.

Yu W, Zhou G, Coburn CA, Zeng Q, Tong L, Dwyer MP, Hu B, Zhong B, Hao J, Ji T, Zan S, Chen L, Mazzola R, Kim JH, Sha D, Selyutin O, Rosenblum SB, Lavey B, Nair AG, Heon Kim S, Keertikar KM, Rokosz L, Agrawal S, Liu R, Xia E, Zhai Y, Curry S, McMonagle P, Ingravallo P, Asante-Appiah E, Chen S, Kozlowski JA.

Bioorg Med Chem Lett. 2016 Oct 1;26(19):4851-4856. doi: 10.1016/j.bmcl.2016.08.002. Epub 2016 Aug 2.

PMID:
27568086
47.

Fifteen-year experience with renal cell carcinoma with associated venous tumor thrombus.

Nooromid MJ, Ju MH, Havelka GE, Kozlowski JM, Kundu SD, Eskandari MK.

Surgery. 2016 Oct;160(4):915-923. doi: 10.1016/j.surg.2016.06.029. Epub 2016 Aug 6.

PMID:
27506867
48.

Comparison of Nitrogen Oxide Metabolism among Diverse Ammonia-Oxidizing Bacteria.

Kozlowski JA, Kits KD, Stein LY.

Front Microbiol. 2016 Jul 12;7:1090. doi: 10.3389/fmicb.2016.01090. eCollection 2016.

49.

Matched and mixed cap derivatives in the tetracyclic indole class of HCV NS5A inhibitors.

Dwyer MP, Keertikar KM, Chen L, Tong L, Selyutin O, Nair AG, Yu W, Zhou G, Lavey BJ, Yang DY, Wong M, Kim SH, Coburn CA, Rosenblum SB, Zeng Q, Jiang Y, Shankar BB, Rizvi R, Nomeir AA, Liu R, Agrawal S, Xia E, Kong R, Zhai Y, Ingravallo P, Asante-Appiah E, Kozlowski JA.

Bioorg Med Chem Lett. 2016 Aug 15;26(16):4106-11. doi: 10.1016/j.bmcl.2016.06.063. Epub 2016 Jun 25.

PMID:
27423481
50.

Aryl or heteroaryl substituted aminal derivatives of HCV NS5A inhibitor MK-8742.

Yu W, Coburn CA, Nair AG, Wong M, Rosenblum SB, Zhou G, Dwyer MP, Tong L, Hu B, Zhong B, Hao J, Ji T, Zan S, Kim SH, Zeng Q, Selyutin O, Chen L, Masse F, Agrawal S, Liu R, Xia E, Zhai Y, Curry S, McMonagle P, Ingravallo P, Asante-Appiah E, Lin M, Kozlowski JA.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3414-20. doi: 10.1016/j.bmcl.2016.06.056. Epub 2016 Jun 22.

PMID:
27394665

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