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Items: 1 to 50 of 521

1.

Hypercapnic tumor microenvironment confers chemoresistance to lung cancer cells by reprogramming mitochondrial metabolism in vitro.

Kikuchi R, Iwai Y, Tsuji T, Watanabe Y, Koyama N, Yamaguchi K, Nakamura H, Aoshiba K.

Free Radic Biol Med. 2019 Jan 10. pii: S0891-5849(18)31303-0. doi: 10.1016/j.freeradbiomed.2019.01.014. [Epub ahead of print]

PMID:
30639568
2.

Combined treatment with the phenolics (-)-epigallocatechin-3-gallate and ferulic acid improves cognition and reduces Alzheimer-like pathology in mice.

Mori T, Koyama N, Tan J, Segawa T, Maeda M, Town T.

J Biol Chem. 2018 Dec 18. pii: jbc.RA118.004280. doi: 10.1074/jbc.RA118.004280. [Epub ahead of print]

3.

Biallelic COLGALT1 variants are associated with cerebral small vessel disease.

Miyatake S, Schneeberger S, Koyama N, Yokochi K, Ohmura K, Shiina M, Mori H, Koshimizu E, Imagawa E, Uchiyama Y, Mitsuhashi S, Frith MC, Fujita A, Satoh M, Taguri M, Tomono Y, Takahashi K, Doi H, Takeuchi H, Nakashima M, Mizuguchi T, Takata A, Miyake N, Saitsu H, Tanaka F, Ogata K, Hennet T, Matsumoto N.

Ann Neurol. 2018 Dec;84(6):843-853. doi: 10.1002/ana.25367. Epub 2018 Nov 30.

4.

MS network-based screening for new antibiotics discovery.

Koyama N, Tomoda H.

J Antibiot (Tokyo). 2019 Jan;72(1):54-56. doi: 10.1038/s41429-018-0109-0. Epub 2018 Oct 23. No abstract available.

PMID:
30353113
5.

Grading of Atrophic Gastritis is Useful for Risk Stratification in Endoscopic Screening for Gastric Cancer.

Kaji K, Hashiba A, Uotani C, Yamaguchi Y, Ueno T, Ohno K, Takabatake I, Wakabayashi T, Doyama H, Ninomiya I, Kiriyama M, Ohyama S, Yoneshima M, Koyama N, Takeda Y, Yasuda K.

Am J Gastroenterol. 2019 Jan;114(1):71-79. doi: 10.1038/s41395-018-0259-5.

PMID:
30315306
6.

Using Parasitic Load to Measure the Effect of Anthropogenic Disturbance on Vervet Monkeys.

Thatcher HR, Downs CT, Koyama NF.

Ecohealth. 2018 Sep;15(3):676-681. doi: 10.1007/s10393-018-1349-y. Epub 2018 Aug 8.

7.

Social network changes during space restriction in zoo chimpanzees.

Koyama NF, Aureli F.

Primates. 2018 Jul 17. doi: 10.1007/s10329-018-0675-6. [Epub ahead of print]

PMID:
30019231
8.

Direct evidence for the age-dependent demise of GNAS-mutated cells in oral fibrous dysplasia.

Isobe Y, Takahashi K, Kiso H, Nakao K, Ikeno M, Koyama N, Sugai M, Shimizu A, Haga H, Bessho K.

Arch Oral Biol. 2018 May 30;93:133-140. doi: 10.1016/j.archoralbio.2018.05.018. [Epub ahead of print]

PMID:
29909118
9.
10.

A Phase I clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer.

Hirooka Y, Kasuya H, Ishikawa T, Kawashima H, Ohno E, Villalobos IB, Naoe Y, Ichinose T, Koyama N, Tanaka M, Kodera Y, Goto H.

BMC Cancer. 2018 May 25;18(1):596. doi: 10.1186/s12885-018-4453-z.

11.

Anti-Rhizopus activity of tanzawaic acids produced by the hot spring-derived fungus Penicillium sp. BF-0005.

Tominaga T, Uchida R, Koyama N, Tomoda H.

J Antibiot (Tokyo). 2018 Jul;71(7):626-632. doi: 10.1038/s41429-018-0049-8. Epub 2018 May 1.

PMID:
29717198
12.

Effective prevention of sorafenib-induced hand-foot syndrome by dried-bonito broth.

Kamimura K, Shinagawa-Kobayashi Y, Goto R, Ogawa K, Yokoo T, Sakamaki A, Abe S, Kamimura H, Suda T, Baba H, Tanaka T, Nozawa Y, Koyama N, Takamura M, Kawai H, Yamagiwa S, Aoyagi Y, Terai S.

Cancer Manag Res. 2018 Apr 17;10:805-813. doi: 10.2147/CMAR.S159370. eCollection 2018.

13.

Prognostic Factors and Efficacy of First-Line Chemotherapy in Patients with Advanced Thymic Carcinoma: A Retrospective Analysis of 286 Patients from NEJ023 Study.

Ko R, Shukuya T, Okuma Y, Tateishi K, Imai H, Iwasawa S, Miyauchi E, Fujiwara A, Sugiyama T, Azuma K, Muraki K, Yamasaki M, Tanaka H, Takashima Y, Soda S, Ishimoto O, Koyama N, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group.

Oncologist. 2018 Oct;23(10):1210-1217. doi: 10.1634/theoncologist.2017-0586. Epub 2018 Mar 22.

PMID:
29567820
14.

Advanced Lung Adenocarcinoma with Nivolumab-associated Dermatomyositis.

Kudo F, Watanabe Y, Iwai Y, Miwa C, Nagai Y, Ota H, Yabe H, Demitsu T, Hagiwara K, Koyama N, Koyama S.

Intern Med. 2018 Aug 1;57(15):2217-2221. doi: 10.2169/internalmedicine.9381-17. Epub 2018 Mar 9.

15.

High incidence and early onset of nivolumab-induced pneumonitis: four case reports and literature review.

Koyama N, Iwase O, Nakashima E, Kishida K, Kondo T, Watanabe Y, Takahashi H, Umebayashi Y, Ogawa Y, Miura H.

BMC Pulm Med. 2018 Jan 30;18(1):23. doi: 10.1186/s12890-018-0592-x.

16.

Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model.

Shinagawa-Kobayashi Y, Kamimura K, Goto R, Ogawa K, Inoue R, Yokoo T, Sakai N, Nagoya T, Sakamaki A, Abe S, Sugitani S, Yanagi M, Fujisawa K, Nozawa Y, Koyama N, Nishina H, Furutani-Seiki M, Sakaida I, Terai S.

Biochem Biophys Res Commun. 2018 Feb 5;496(2):556-561. doi: 10.1016/j.bbrc.2018.01.057. Epub 2018 Jan 10.

PMID:
29331379
17.

Effectiveness of nanoparticle albumin-bound paclitaxel plus carboplatin in non-small lung cancer patients with malignant pleural effusion.

Koyama N, Watanabe Y, Iwai Y, Miwa C, Nagai Y, Aoshiba K, Nakamura H.

Neoplasma. 2018;65(1):132-139. doi: 10.4149/neo_2018_170206N78.

PMID:
29322797
18.

Myocardial perfusion reserve quantified by cardiac magnetic resonance imaging is associated with late gadolinium enhancement in hypertrophic cardiomyopathy.

Tezuka D, Kosuge H, Terashima M, Koyama N, Kishida T, Tada Y, Suzuki JI, Sasano T, Ashikaga T, Hirao K, Isobe M.

Heart Vessels. 2018 May;33(5):513-520. doi: 10.1007/s00380-017-1088-y. Epub 2017 Nov 22.

PMID:
29168014
19.

Activation of apoptosis inhibitor of macrophage is a sensitive diagnostic marker for NASH-associated hepatocellular carcinoma.

Koyama N, Yamazaki T, Kanetsuki Y, Hirota J, Asai T, Mitsumoto Y, Mizuno M, Shima T, Kanbara Y, Arai S, Miyazaki T, Okanoue T.

J Gastroenterol. 2018 Jun;53(6):770-779. doi: 10.1007/s00535-017-1398-y. Epub 2017 Oct 30.

PMID:
29086016
20.

Minocycline Directly Enhances the Self-Renewal of Adult Neural Precursor Cells.

Kuroda A, Fuchigami T, Fuke S, Koyama N, Ikenaka K, Hitoshi S.

Neurochem Res. 2018 Jan;43(1):219-226. doi: 10.1007/s11064-017-2422-6. Epub 2017 Oct 28.

PMID:
29081002
21.

Neurodevelopmental outcomes at 3 years old for infants with birth weights under 500 g.

Nagara S, Kouwaki M, Togawa T, Sugiura T, Okada M, Koyama N.

Pediatr Neonatol. 2018 Jun;59(3):274-280. doi: 10.1016/j.pedneo.2017.09.005. Epub 2017 Sep 21.

22.

Durability and flexibility of chimpanzee grooming patterns during a period of dominance instability.

Koyama NF, Ronkainen K, Aureli F.

Am J Primatol. 2017 Nov;79(11). doi: 10.1002/ajp.22713. Epub 2017 Oct 12.

PMID:
29023900
23.

A metabolomics guided exploration of marine natural product chemical space.

Floros DJ, Jensen PR, Dorrestein PC, Koyama N.

Metabolomics. 2016 Sep;12(9). pii: 145. doi: 10.1007/s11306-016-1087-5. Epub 2016 Aug 9.

24.

A clinicopathological study of surgically resected lung cancer in patients with usual interstitial pneumonia.

Watanabe Y, Kawabata Y, Koyama N, Ikeya T, Hoshi E, Takayanagi N, Koyama S.

Respir Med. 2017 Aug;129:158-163. doi: 10.1016/j.rmed.2017.06.015. Epub 2017 Jun 23.

PMID:
28732824
25.

Circulatory CNP Rescues Craniofacial Hypoplasia in Achondroplasia.

Yamanaka S, Nakao K, Koyama N, Isobe Y, Ueda Y, Kanai Y, Kondo E, Fujii T, Miura M, Yasoda A, Nakao K, Bessho K.

J Dent Res. 2017 Dec;96(13):1526-1534. doi: 10.1177/0022034517716437. Epub 2017 Jun 23.

PMID:
28644737
26.

Utilization of the Bridging Strategy for the Development of New Drugs in Oncology to Avoid Drug Lag.

Kogure S, Koyama N, Hidaka S.

J Clin Pharmacol. 2017 Nov;57(11):1479-1490. doi: 10.1002/jcph.951. Epub 2017 Jun 19.

PMID:
28628225
27.

Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.

Mori T, Koyama N, Tan J, Segawa T, Maeda M, Town T.

J Biol Chem. 2017 Jul 7;292(27):11310-11325. doi: 10.1074/jbc.M116.762658. Epub 2017 May 16.

28.

Expression of A-kinase anchor protein 13 and Rho-associated coiled-coil containing protein kinase in restituted and regenerated mucosal epithelial cells following mucosal injury and colorectal cancer cells in mouse models.

Kangawa Y, Yoshida T, Tanaka T, Kataoka A, Koyama N, Ohsumi T, Hayashi SM, Shibutani M.

Exp Toxicol Pathol. 2017 Sep 5;69(7):443-450. doi: 10.1016/j.etp.2017.04.002. Epub 2017 Apr 20.

PMID:
28434818
29.

A case of pediatric multiple sclerosis presenting with a tumefactive demyelinating lesion.

Majima H, Ito T, Koyama N.

Rinsho Shinkeigaku. 2017 Feb 25;57(2):88-91. doi: 10.5692/clinicalneurol.cn-000920. Epub 2017 Jan 28. Review. Japanese.

PMID:
28132974
30.

Erratum: Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides.

Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL Jr, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, De Mot R, Moore BS, Medema MH, Dorrestein PC.

Nat Microbiol. 2017 Jan 23;2:17010. doi: 10.1038/nmicrobiol.2017.10. No abstract available.

PMID:
28112718
31.

Distinct Benefit of Overall Survival between Patients with Non-Small-Cell Lung Cancer Harboring EGFR Exon 19 Deletion and Exon 21 L858R Substitution.

Koyama N, Watanabe Y, Iwai Y, Kawamura R, Miwa C, Nagai Y, Hagiwara K, Koyama S.

Chemotherapy. 2017;62(3):151-158. doi: 10.1159/000454944. Epub 2017 Jan 21.

PMID:
28110331
32.

A case report of mitochondrial respiratory chain disorder in the neonatal period for which home mechanical ventilation was introduced.

Sugimoto M, Togawa T, Aiba K, Koyama N, Yokochi K, Murayama K, Ohtake A.

No To Hattatsu. 2017 Jan;49(1):37-41. Japanese.

PMID:
30011153
33.

Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer.

Koyama N, Tomoda K, Matsuda M, Fujita Y, Yamamoto Y, Hontsu S, Tasaki M, Yoshikawa M, Kimura H.

Intern Med. 2016;55(24):3635-3639. Epub 2016 Dec 15.

34.

Evaluation for a mutagenicity of aristolochic acid by Pig-a and PIGRET assays in rats.

Koyama N, Yonezawa Y, Nakamura M, Sanada H.

Mutat Res. 2016 Nov 15;811:80-85. doi: 10.1016/j.mrgentox.2015.12.004. Epub 2015 Dec 23.

PMID:
27931820
35.

Evaluation of the PIGRET assay in rats by single oral dosing with azidothymidine.

Sanada H, Ohsumi T, Koyama N, Miyashita T, Hashimoto K.

Mutat Res. 2016 Nov 15;811:65-69. doi: 10.1016/j.mrgentox.2016.02.005. Epub 2016 Mar 2.

PMID:
27931817
36.

The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals.

Kimoto T, Horibata K, Miura D, Chikura S, Okada Y, Ukai A, Itoh S, Nakayama S, Sanada H, Koyama N, Muto S, Uno Y, Yamamoto M, Suzuki Y, Fukuda T, Goto K, Wada K, Kyoya T, Shigano M, Takasawa H, Hamada S, Adachi H, Uematsu Y, Tsutsumi E, Hori H, Kikuzuki R, Ogiwara Y, Yoshida I, Maeda A, Narumi K, Fujiishi Y, Morita T, Yamada M, Honma M.

Mutat Res. 2016 Nov 15;811:3-15. doi: 10.1016/j.mrgentox.2016.10.003. Epub 2016 Oct 21.

37.

Clinical benefit of eribulin (Halaven®) in the treatment of advanced soft tissue sarcoma patients and the novel anti-tumor mechanisms.

Koyama N, Taniguchi S, Kodama K, Tohyama O, Hasegawa H, Semba T.

Nihon Yakurigaku Zasshi. 2016;148(6):329-333. doi: 10.1254/fpj.148.329. Review. Japanese. No abstract available.

PMID:
27904013
38.

Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis.

Shinzaki S, Matsuoka K, Iijima H, Mizuno S, Serada S, Fujimoto M, Arai N, Koyama N, Morii E, Watanabe M, Hibi T, Kanai T, Takehara T, Naka T.

J Crohns Colitis. 2017 Jan;11(1):84-91. doi: 10.1093/ecco-jcc/jjw132. Epub 2016 Jul 27.

39.

Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides.

Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL Jr, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, De Mot R, Moore BS, Medema MH, Dorrestein PC.

Nat Microbiol. 2016 Oct 31;2:16197. doi: 10.1038/nmicrobiol.2016.197. Erratum in: Nat Microbiol. 2017 Jan 23;2:17010.

40.

Treatments and outcomes of advanced/recurrent non-small cell lung cancer harboring the EGFR T790M mutation: a retrospective observational study of 141 patients in Japan.

Yamane Y, Shiono A, Ishii Y, Isobe K, Miyauchi E, Kishi K, Nishino M, Sugawara S, Ko R, Koyama N, Yabuki Y, Kobayashi K.

Jpn J Clin Oncol. 2016 Dec;46(12):1135-1142. Epub 2016 Sep 21.

PMID:
27655904
41.

Variability of breathing during wakefulness while using CPAP predicts adherence.

Fujita Y, Yamauchi M, Uyama H, Kumamoto M, Koyama N, Yoshikawa M, Strohl KP, Kimura H.

Respirology. 2017 Feb;22(2):386-393. doi: 10.1111/resp.12900. Epub 2016 Sep 13.

PMID:
27623518
42.

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N.

Nat Biotechnol. 2016 Aug 9;34(8):828-837. doi: 10.1038/nbt.3597.

43.

Superior Mesenteric Vein Thrombosis Associated with Hormonal Contraceptive Use.

Koyama N.

Case Rep Gastroenterol. 2016 Jun 6;10(2):264-8. doi: 10.1159/000446838. eCollection 2016 May-Aug.

44.

Structure-Activity Analysis of Gram-positive Bacterium-producing Lasso Peptides with Anti-mycobacterial Activity.

Inokoshi J, Koyama N, Miyake M, Shimizu Y, Tomoda H.

Sci Rep. 2016 Jul 26;6:30375. doi: 10.1038/srep30375.

45.

Assessment of hepatic fibrosis with superb microvascular imaging in hepatitis C virus-associated chronic liver diseases.

Koyama N, Hata J, Sato T, Tomiyama Y, Hino K.

Hepatol Res. 2017 May;47(6):593-597. doi: 10.1111/hepr.12776. Epub 2016 Aug 15.

PMID:
27433927
46.

Anti-EGFR scFv tetramer (tetrabody) with a stable monodisperse structure, strong anticancer effect, and a long in vivo half-life.

Asano R, Koyama N, Hagiwara Y, Masakari Y, Orimo R, Arai K, Ogata H, Furumoto S, Umetsu M, Kumagai I.

FEBS Open Bio. 2016 May 16;6(6):594-602. doi: 10.1002/2211-5463.12073. eCollection 2016 Jun.

47.

IgE-dependent mechanism and successful desensitization of erythritol allergy.

Sugiura S, Kondo Y, Tsuge I, Nakagawa T, Kando N, Ito K, Koyama N.

Ann Allergy Asthma Immunol. 2016 Sep;117(3):320-321.e1. doi: 10.1016/j.anai.2016.06.019. Epub 2016 Jul 9. No abstract available.

PMID:
27406010
48.

Asymptomatic C-reactive protein elevation in neutropenic children.

Sugiura S, Ito T, Koyama N, Sasaki N, Ikai H, Imanaka Y.

Pediatr Int. 2017 Jan;59(1):23-28. doi: 10.1111/ped.13077. Epub 2016 Sep 21.

PMID:
27362735
49.

The Occurrence of Postconflict Skills in Captive Immature Chimpanzees (Pan troglodytes).

Farooqi SH, Koyama NF.

Int J Primatol. 2016;37:185-199. Epub 2016 Feb 22.

50.

Discovery of Benzofuran Derivatives that Collaborate with Insulin-Like Growth Factor 1 (IGF-1) to Promote Neuroprotection.

Wakabayashi T, Tokunaga N, Tokumaru K, Ohra T, Koyama N, Hayashi S, Yamada R, Shirasaki M, Inui Y, Tsukamoto T.

J Med Chem. 2016 May 26;59(10):5109-14. doi: 10.1021/acs.jmedchem.6b00191. Epub 2016 May 10.

PMID:
27163512

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