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Items: 1 to 50 of 139

1.

Distinct Metabolic Patterns During Microglial Remodeling by Oleate and Palmitate.

Chausse B, Kakimoto PA, Caldeira-da-Silva CC, Chaves-Filho AB, Yoshinaga MY, da Silva RP, Miyamoto S, Kowaltowski AJ.

Biosci Rep. 2019 Mar 13. pii: BSR20190072. doi: 10.1042/BSR20190072. [Epub ahead of print]

PMID:
30867255
2.

Resilient hepatic mitochondrial function and lack of iNOS dependence in diet-induced insulin resistance.

Kakimoto PA, Chausse B, Caldeira da Silva CC, Donato Júnior J, Kowaltowski AJ.

PLoS One. 2019 Feb 4;14(2):e0211733. doi: 10.1371/journal.pone.0211733. eCollection 2019.

3.

Plan S: Unrealistic capped fee structure.

Kowaltowski AJ, Oliveira MF.

Science. 2019 Feb 1;363(6426):461. doi: 10.1126/science.aaw5815. No abstract available.

PMID:
30705175
4.

A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats.

Ferreira JCB, Campos JC, Qvit N, Qi X, Bozi LHM, Bechara LRG, Lima VM, Queliconi BB, Disatnik MH, Dourado PMM, Kowaltowski AJ, Mochly-Rosen D.

Nat Commun. 2019 Jan 18;10(1):329. doi: 10.1038/s41467-018-08276-6.

5.

Mitochondrial alternative oxidase is determinant for growth and sporulation in the early diverging fungus Blastocladiella emersonii.

Luévano-Martínez LA, Caldeira da Silva CC, Nicastro GG, Schumacher RI, Kowaltowski AJ, Gomes SL.

Fungal Biol. 2019 Jan;123(1):59-65. doi: 10.1016/j.funbio.2018.11.005. Epub 2018 Nov 16.

PMID:
30654958
6.

Strategies to detect mitochondrial oxidants.

Kowaltowski AJ.

Redox Biol. 2019 Feb;21:101065. doi: 10.1016/j.redox.2018.101065. Epub 2018 Dec 5. Review.

7.

Fasting promotes functional changes in liver mitochondria.

Menezes-Filho SL, Amigo I, Luévano-Martínez LA, Kowaltowski AJ.

Biochim Biophys Acta Bioenerg. 2019 Feb 1;1860(2):129-135. doi: 10.1016/j.bbabio.2018.11.017. Epub 2018 Nov 20.

PMID:
30465749
8.

Calorie restriction attenuates hypertrophy-induced redox imbalance and mitochondrial ATP-sensitive K+ channel repression.

David CEB, Lucas AMB, Araújo MTS, Coelho BN, Neto JBS, Portela BRC, Varela ALN, Kowaltowski AJ, Facundo HT.

J Nutr Biochem. 2018 Dec;62:87-94. doi: 10.1016/j.jnutbio.2018.08.008. Epub 2018 Sep 5.

PMID:
30286377
9.

Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition.

Vercesi AE, Castilho RF, Kowaltowski AJ, de Oliveira HCF, de Souza-Pinto NC, Figueira TR, Busanello ENB.

Free Radic Biol Med. 2018 Dec;129:1-24. doi: 10.1016/j.freeradbiomed.2018.08.034. Epub 2018 Aug 31. Review.

PMID:
30172747
10.

Topological characterization of the mitochondrial phospholipid scramblase 3.

Luévano-Martínez LA, Kowaltowski AJ.

FEBS Lett. 2017 Dec;591(24):4056-4066. doi: 10.1002/1873-3468.12917. Epub 2017 Nov 28.

11.

Cell culture models of fatty acid overload: Problems and solutions.

Alsabeeh N, Chausse B, Kakimoto PA, Kowaltowski AJ, Shirihai O.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Feb;1863(2):143-151. doi: 10.1016/j.bbalip.2017.11.006. Epub 2017 Nov 15. Review.

12.

Early Postnatal Cardiomyocyte Proliferation Requires High Oxidative Energy Metabolism.

de Carvalho AETS, Bassaneze V, Forni MF, Keusseyan AA, Kowaltowski AJ, Krieger JE.

Sci Rep. 2017 Nov 13;7(1):15434. doi: 10.1038/s41598-017-15656-3.

13.

Caloric Restriction Promotes Structural and Metabolic Changes in the Skin.

Forni MF, Peloggia J, Braga TT, Chinchilla JEO, Shinohara J, Navas CA, Camara NOS, Kowaltowski AJ.

Cell Rep. 2017 Sep 12;20(11):2678-2692. doi: 10.1016/j.celrep.2017.08.052.

14.

Single Cell Oxygen Mapping (SCOM) by Scanning Electrochemical Microscopy Uncovers Heterogeneous Intracellular Oxygen Consumption.

Santos CS, Kowaltowski AJ, Bertotti M.

Sci Rep. 2017 Sep 12;7(1):11428. doi: 10.1038/s41598-017-11956-w.

15.

An active-learning methodology for teaching oxidative phosphorylation.

Forni MF, Garcia-Neto W, Kowaltowski AJ, Marson GA.

Med Educ. 2017 Nov;51(11):1169-1170. doi: 10.1111/medu.13418. Epub 2017 Aug 30. No abstract available.

PMID:
28857228
16.

Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition.

Menezes-Filho SL, Amigo I, Prado FM, Ferreira NC, Koike MK, Pinto IFD, Miyamoto S, Montero EFS, Medeiros MHG, Kowaltowski AJ.

Free Radic Biol Med. 2017 Sep;110:219-227. doi: 10.1016/j.freeradbiomed.2017.06.013. Epub 2017 Jun 19.

PMID:
28642067
17.

Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure.

Campos JC, Queliconi BB, Bozi LHM, Bechara LRG, Dourado PMM, Andres AM, Jannig PR, Gomes KMS, Zambelli VO, Rocha-Resende C, Guatimosim S, Brum PC, Mochly-Rosen D, Gottlieb RA, Kowaltowski AJ, Ferreira JCB.

Autophagy. 2017 Aug 3;13(8):1304-1317. doi: 10.1080/15548627.2017.1325062.

18.

Lack of XPC leads to a shift between respiratory complexes I and II but sensitizes cells to mitochondrial stress.

Mori MP, Costa RA, Soltys DT, Freire TS, Rossato FA, Amigo I, Kowaltowski AJ, Vercesi AE, de Souza-Pinto NC.

Sci Rep. 2017 Mar 13;7(1):155. doi: 10.1038/s41598-017-00130-x.

19.

Calorie restriction promotes cardiolipin biosynthesis and distribution between mitochondrial membranes.

Luévano-Martínez LA, Forni MF, Peloggia J, Watanabe IS, Kowaltowski AJ.

Mech Ageing Dev. 2017 Mar;162:9-17. doi: 10.1016/j.mad.2017.02.004. Epub 2017 Feb 14.

PMID:
28213011
20.

Soluble Uric Acid Activates the NLRP3 Inflammasome.

Braga TT, Forni MF, Correa-Costa M, Ramos RN, Barbuto JA, Branco P, Castoldi A, Hiyane MI, Davanso MR, Latz E, Franklin BS, Kowaltowski AJ, Camara NO.

Sci Rep. 2017 Jan 13;7:39884. doi: 10.1038/srep39884.

21.

High Osmolarity Environments Activate the Mitochondrial Alternative Oxidase in Debaryomyces Hansenii.

Garcia-Neto W, Cabrera-Orefice A, Uribe-Carvajal S, Kowaltowski AJ, Alberto Luévano-Martínez L.

PLoS One. 2017 Jan 6;12(1):e0169621. doi: 10.1371/journal.pone.0169621. eCollection 2017.

22.

Bicarbonate Increases Ischemia-Reperfusion Damage by Inhibiting Mitophagy.

Queliconi BB, Kowaltowski AJ, Gottlieb RA.

PLoS One. 2016 Dec 14;11(12):e0167678. doi: 10.1371/journal.pone.0167678. eCollection 2016.

23.

Diazoxide prevents reactive oxygen species and mitochondrial damage, leading to anti-hypertrophic effects.

Lucas AM, Caldas FR, da Silva AP, Ventura MM, Leite IM, Filgueiras AB, Silva CG, Kowaltowski AJ, Facundo HT.

Chem Biol Interact. 2017 Jan 5;261:50-55. doi: 10.1016/j.cbi.2016.11.012. Epub 2016 Nov 17.

PMID:
27867086
24.

Mitochondrial form, function and signalling in aging.

Amigo I, da Cunha FM, Forni MF, Garcia-Neto W, Kakimoto PA, Luévano-Martínez LA, Macedo F, Menezes-Filho SL, Peloggia J, Kowaltowski AJ.

Biochem J. 2016 Oct 15;473(20):3421-3449. Review.

PMID:
27729586
25.

Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity.

Amigo I, Menezes-Filho SL, Luévano-Martínez LA, Chausse B, Kowaltowski AJ.

Aging Cell. 2017 Feb;16(1):73-81. doi: 10.1111/acel.12527. Epub 2016 Sep 13.

26.

Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice.

Reis FC, Branquinho JL, Brandão BB, Guerra BA, Silva ID, Frontini A, Thomou T, Sartini L, Cinti S, Kahn CR, Festuccia WT, Kowaltowski AJ, Mori MA.

Aging (Albany NY). 2016 Jun;8(6):1201-22. doi: 10.18632/aging.100970.

27.

Underestimation of the Maximal Capacity of the Mitochondrial Electron Transport System in Oligomycin-Treated Cells.

Ruas JS, Siqueira-Santos ES, Amigo I, Rodrigues-Silva E, Kowaltowski AJ, Castilho RF.

PLoS One. 2016 Mar 7;11(3):e0150967. doi: 10.1371/journal.pone.0150967. eCollection 2016.

28.

Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice.

Magdalon J, Chimin P, Belchior T, Neves RX, Vieira-Lara MA, Andrade ML, Farias TS, Bolsoni-Lopes A, Paschoal VA, Yamashita AS, Kowaltowski AJ, Festuccia WT.

Biochim Biophys Acta. 2016 May;1861(5):430-8. doi: 10.1016/j.bbalip.2016.02.023. Epub 2016 Feb 27.

PMID:
26923434
29.

Effects of high fat diets on rodent liver bioenergetics and oxidative imbalance.

Kakimoto PA, Kowaltowski AJ.

Redox Biol. 2016 Aug;8:216-25. doi: 10.1016/j.redox.2016.01.009. Epub 2016 Jan 14. Review.

30.

Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity.

Cerqueira FM, Chausse B, Baranovski BM, Liesa M, Lewis EC, Shirihai OS, Kowaltowski AJ.

FEBS J. 2016 Mar;283(5):822-33. doi: 10.1111/febs.13632. Epub 2016 Feb 15.

31.

Murine Mesenchymal Stem Cell Commitment to Differentiation Is Regulated by Mitochondrial Dynamics.

Forni MF, Peloggia J, Trudeau K, Shirihai O, Kowaltowski AJ.

Stem Cells. 2016 Mar;34(3):743-55. doi: 10.1002/stem.2248. Epub 2015 Dec 21.

32.

Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes.

da Cunha FM, Torelli NQ, Kowaltowski AJ.

Oxid Med Cell Longev. 2015;2015:482582. doi: 10.1155/2015/482582. Epub 2015 Oct 25. Review.

33.

Phosphatidylglycerol-derived phospholipids have a universal, domain-crossing role in stress responses.

Luévano-Martínez LA, Kowaltowski AJ.

Arch Biochem Biophys. 2015 Nov 1;585:90-97. doi: 10.1016/j.abb.2015.09.015. Epub 2015 Sep 21. Review.

PMID:
26391924
34.

Bioenergetic profiling in the skin.

Forni MF, Chausse B, Peloggia J, Kowaltowski AJ.

Exp Dermatol. 2016 Feb;25(2):147-8. doi: 10.1111/exd.12856. Epub 2015 Oct 13. No abstract available.

PMID:
26343263
35.

Mitochondrial ATP-sensitive potassium channel opening inhibits isoproterenol-induced cardiac hypertrophy by preventing oxidative damage.

Lemos Caldas FR, Rocha Leite IM, Tavarez Filgueiras AB, de Figueiredo Júnior IL, Gomes Marques de Sousa TA, Martins PR, Kowaltowski AJ, Fernandes Facundo Hd.

J Cardiovasc Pharmacol. 2015 Apr;65(4):393-7. doi: 10.1097/FJC.0000000000000210.

PMID:
25850726
36.

Cardiolipin is a key determinant for mtDNA stability and segregation during mitochondrial stress.

Luévano-Martínez LA, Forni MF, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ.

Biochim Biophys Acta. 2015 Jun-Jul;1847(6-7):587-98. doi: 10.1016/j.bbabio.2015.03.007. Epub 2015 Apr 2.

37.

Intermittent fasting results in tissue-specific changes in bioenergetics and redox state.

Chausse B, Vieira-Lara MA, Sanchez AB, Medeiros MH, Kowaltowski AJ.

PLoS One. 2015 Mar 6;10(3):e0120413. doi: 10.1371/journal.pone.0120413. eCollection 2015.

38.

H2O2 release from the very long chain acyl-CoA dehydrogenase.

Kakimoto PA, Tamaki FK, Cardoso AR, Marana SR, Kowaltowski AJ.

Redox Biol. 2015;4:375-80. doi: 10.1016/j.redox.2015.02.003. Epub 2015 Feb 20.

39.

RTG1- and RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in Saccharomyces cerevisiae.

Torelli NQ, Ferreira-Júnior JR, Kowaltowski AJ, da Cunha FM.

Free Radic Biol Med. 2015 Apr;81:30-7. doi: 10.1016/j.freeradbiomed.2014.12.025. Epub 2015 Jan 8.

PMID:
25578655
40.

Aldehydic load and aldehyde dehydrogenase 2 profile during the progression of post-myocardial infarction cardiomyopathy: benefits of Alda-1.

Gomes KM, Bechara LR, Lima VM, Ribeiro MA, Campos JC, Dourado PM, Kowaltowski AJ, Mochly-Rosen D, Ferreira JC.

Int J Cardiol. 2015 Jan 20;179:129-38. doi: 10.1016/j.ijcard.2014.10.140. Epub 2014 Oct 23.

41.

Aldehyde dehydrogenase 2 activation in heart failure restores mitochondrial function and improves ventricular function and remodelling.

Gomes KM, Campos JC, Bechara LR, Queliconi B, Lima VM, Disatnik MH, Magno P, Chen CH, Brum PC, Kowaltowski AJ, Mochly-Rosen D, Ferreira JC.

Cardiovasc Res. 2014 Sep 1;103(4):498-508. doi: 10.1093/cvr/cvu125. Epub 2014 May 9.

42.

Intermittent fasting induces hypothalamic modifications resulting in low feeding efficiency, low body mass and overeating.

Chausse B, Solon C, Caldeira da Silva CC, Masselli Dos Reis IG, Manchado-Gobatto FB, Gobatto CA, Velloso LA, Kowaltowski AJ.

Endocrinology. 2014 Jul;155(7):2456-66. doi: 10.1210/en.2013-2057. Epub 2014 May 5.

PMID:
24797627
43.

An anoxia-starvation model for ischemia/reperfusion in C. elegans.

Queliconi BB, Kowaltowski AJ, Nehrke K.

J Vis Exp. 2014 Mar 11;(85). doi: 10.3791/51231.

44.

Dietary restriction in cerebral bioenergetics and redox state.

Amigo I, Kowaltowski AJ.

Redox Biol. 2014 Jan 11;2:296-304. doi: 10.1016/j.redox.2013.12.021. eCollection 2014. Review.

45.

Diet-sensitive sources of reactive oxygen species in liver mitochondria: role of very long chain acyl-CoA dehydrogenases.

Cardoso AR, Kakimoto PA, Kowaltowski AJ.

PLoS One. 2013 Oct 7;8(10):e77088. doi: 10.1371/journal.pone.0077088. eCollection 2013.

46.

Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma cruzi.

Paes LS, Suárez Mantilla B, Zimbres FM, Pral EM, Diogo de Melo P, Tahara EB, Kowaltowski AJ, Elias MC, Silber AM.

PLoS One. 2013 Jul 22;8(7):e69419. doi: 10.1371/journal.pone.0069419. Print 2013.

47.

Deletion of the transcriptional regulator opi1p decreases cardiolipin content and disrupts mitochondrial metabolism in Saccharomyces cerevisiae.

Luévano-Martínez LA, Appolinario P, Miyamoto S, Uribe-Carvajal S, Kowaltowski AJ.

Fungal Genet Biol. 2013 Nov;60:150-8. doi: 10.1016/j.fgb.2013.03.005. Epub 2013 Apr 8.

48.

Calorie restriction hysteretically primes aging Saccharomyces cerevisiae toward more effective oxidative metabolism.

Tahara EB, Cunha FM, Basso TO, Della Bianca BE, Gombert AK, Kowaltowski AJ.

PLoS One. 2013;8(2):e56388. doi: 10.1371/journal.pone.0056388. Epub 2013 Feb 11.

49.

Exercise training restores cardiac protein quality control in heart failure.

Campos JC, Queliconi BB, Dourado PM, Cunha TF, Zambelli VO, Bechara LR, Kowaltowski AJ, Brum PC, Mochly-Rosen D, Ferreira JC.

PLoS One. 2012;7(12):e52764. doi: 10.1371/journal.pone.0052764. Epub 2012 Dec 27.

50.

Mitochondria as a source of reactive oxygen and nitrogen species: from molecular mechanisms to human health.

Figueira TR, Barros MH, Camargo AA, Castilho RF, Ferreira JC, Kowaltowski AJ, Sluse FE, Souza-Pinto NC, Vercesi AE.

Antioxid Redox Signal. 2013 Jun 1;18(16):2029-74. doi: 10.1089/ars.2012.4729. Epub 2013 Feb 19. Review.

PMID:
23244576

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