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Items: 41

1.

Author Correction: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice.

Gu H, Ma Z, Wang J, Zhu T, Du N, Shatara A, Yi X, Kowala MC, Du Y.

Sci Rep. 2018 Oct 25;8(1):16077. doi: 10.1038/s41598-018-31443-0.

2.

A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy.

Fujihara CK, Kowala MC, Breyer MD, Sena CR, Rodrigues MV, Arias SCA, Fanelli C, Malheiros DM, Jadhav PK, Montrose-Rafizadeh C, Krieger JE, Zatz R.

Sci Rep. 2017 Aug 11;7(1):7899. doi: 10.1038/s41598-017-08383-2.

3.

Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats.

Estridge TB, Dey AB, Reidy C, Yu X, Zhang Y, Hartley M, Milligan PL, Jin N, Kowala MC, Leohr JK, Fretland AJ, Mabry TE, Luffer-Atlas D, Luo MJ.

J Pharmacol Exp Ther. 2017 Jul;362(1):108-118. doi: 10.1124/jpet.117.240242. Epub 2017 May 2.

PMID:
28465372
4.

Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice.

Gu H, Ma Z, Wang J, Zhu T, Du N, Shatara A, Yi X, Kowala MC, Du Y.

Sci Rep. 2017 Mar 28;7(1):492. doi: 10.1038/s41598-017-00461-9. Erratum in: Sci Rep. 2018 Oct 25;8(1):16077.

5.

Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody.

Schroeder KM, Beyer TP, Hansen RJ, Han B, Pickard RT, Wroblewski VJ, Kowala MC, Eacho PI.

J Lipid Res. 2015 Nov;56(11):2124-32. doi: 10.1194/jlr.M061903. Epub 2015 Sep 20.

6.

Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms.

van den Borne P, van der Laan SW, Bovens SM, Koole D, Kowala MC, Michael LF, Schoneveld AH, van de Weg SM, Velema E, de Vries JP, de Borst GJ, Moll FL, de Kleijn DP, Quax PH, Hoefer IE, Pasterkamp G.

PLoS One. 2014 Jan 27;9(1):e86522. doi: 10.1371/journal.pone.0086522. eCollection 2014.

7.

Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion.

Miles RR, Perry W, Haas JV, Mosior MK, N'Cho M, Wang JW, Yu P, Calley J, Yue Y, Carter Q, Han B, Foxworthy P, Kowala MC, Ryan TP, Solenberg PJ, Michael LF.

J Biol Chem. 2013 Mar 1;288(9):6386-96. doi: 10.1074/jbc.M112.410092. Epub 2013 Jan 15.

8.

Opportunities for pharmacotherapy at the intersection of metabolic syndrome and hemostasis.

Michael LF, Rao V, McCollam P, Kowala MC, Wetterau J.

Curr Pharm Biotechnol. 2011 Sep;12(9):1463-80. Review.

PMID:
21401518
9.

Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease.

Cao G, Qian YW, Kowala MC, Konrad RJ.

Endocr Metab Immune Disord Drug Targets. 2008 Dec;8(4):238-43. Review.

PMID:
19075777
10.

A nonpeptide, piperidine renin inhibitor provides renal and cardiac protection in double-transgenic mice expressing human renin and angiotensinogen genes.

Major TC, Olszewski B, Rosebury W, Okerberg C, Carlson T, Ostroski R, Schroeder R, Kowala MC, Leadley R.

Cardiovasc Drugs Ther. 2008 Dec;22(6):469-78. doi: 10.1007/s10557-008-6131-x. Epub 2008 Aug 5.

PMID:
18679781
11.

Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice.

Park TS, Rosebury W, Kindt EK, Kowala MC, Panek RL.

Pharmacol Res. 2008 Jul;58(1):45-51. doi: 10.1016/j.phrs.2008.06.005. Epub 2008 Jun 20.

PMID:
18611440
12.

The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay.

Major TC, Dhamija S, Black N, Liachenko S, Morenko B, Sobocinski G, Okerberg C, Tinholt P, Madore S, Kowala MC.

J Pharmacol Exp Ther. 2008 Jun;325(3):723-31. doi: 10.1124/jpet.107.133892. Epub 2008 Mar 7.

PMID:
18326812
13.

Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors.

Park WK, Kennedy RM, Larsen SD, Miller S, Roth BD, Song Y, Steinbaugh BA, Sun K, Tait BD, Kowala MC, Trivedi BK, Auerbach B, Askew V, Dillon L, Hanselman JC, Lin Z, Lu GH, Robertson A, Sekerke C.

Bioorg Med Chem Lett. 2008 Feb 1;18(3):1151-6. Epub 2007 Dec 5.

PMID:
18155906
14.

The Guinea pig as a preclinical model for demonstrating the efficacy and safety of statins.

Madsen CS, Janovitz E, Zhang R, Nguyen-Tran V, Ryan CS, Yin X, Monshizadegan H, Chang M, D'Arienzo C, Scheer S, Setters R, Search D, Chen X, Zhuang S, Kunselman L, Peters A, Harrity T, Apedo A, Huang C, Cuff CA, Kowala MC, Blanar MA, Sun CQ, Robl JA, Stein PD.

J Pharmacol Exp Ther. 2008 Feb;324(2):576-86. Epub 2007 Nov 6.

PMID:
17986646
15.

Pyrazole inhibitors of HMG-CoA reductase: an attempt to dramatically reduce synthetic complexity through minimal analog re-design.

Larsen SD, Poel TJ, Filipski KJ, Kohrt JT, Pfefferkorn JA, Sorenson RJ, Tait BD, Askew V, Dillon L, Hanselman JC, Lu GH, Robertson A, Sekerke C, Kowala MC, Auerbach BJ.

Bioorg Med Chem Lett. 2007 Oct 15;17(20):5567-72. Epub 2007 Aug 11.

PMID:
17764936
16.

Dual angiotensin II and endothelin A receptor antagonists: synthesis of 2'-substituted N-3-isoxazolyl biphenylsulfonamides with improved potency and pharmacokinetics.

Murugesan N, Gu Z, Fadnis L, Tellew JE, Baska RA, Yang Y, Beyer SM, Monshizadegan H, Dickinson KE, Valentine MT, Humphreys WG, Lan SJ, Ewing WR, Carlson KE, Kowala MC, Zahler R, Macor JE.

J Med Chem. 2005 Jan 13;48(1):171-9.

PMID:
15634011
17.

Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension.

Kowala MC, Murugesan N, Tellew J, Carlson K, Monshizadegan H, Ryan C, Gu Z, Kane B, Fadnis L, Baska RA, Beyer S, Arthur S, Dickinson K, Zhang D, Perrone M, Ferrer P, Giancarli M, Baumann J, Bird E, Panchal B, Yang Y, Trippodo N, Barrish J, Macor JE.

J Pharmacol Exp Ther. 2004 Apr;309(1):275-84. Epub 2004 Jan 12.

PMID:
14718594
18.

Discovery of 4'-[(imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/angiotensin II receptor antagonists.

Tellew JE, Baska RA, Beyer SM, Carlson KE, Cornelius LA, Fadnis L, Gu Z, Kunst BL, Kowala MC, Monshizadegan H, Murugesan N, Ryan CS, Valentine MT, Yang Y, Macor JE.

Bioorg Med Chem Lett. 2003 Mar 24;13(6):1093-6.

PMID:
12643919
19.

Discovery of N-isoxazolyl biphenylsulfonamides as potent dual angiotensin II and endothelin A receptor antagonists.

Murugesan N, Tellew JE, Gu Z, Kunst BL, Fadnis L, Cornelius LA, Baska RA, Yang Y, Beyer SM, Monshizadegan H, Dickinson KE, Panchal B, Valentine MT, Chong S, Morrison RA, Carlson KE, Powell JR, Moreland S, Barrish JC, Kowala MC, Macor JE.

J Med Chem. 2002 Aug 29;45(18):3829-35.

PMID:
12190306
20.
21.

Increased severity of glomerulonephritis in C-C chemokine receptor 2 knockout mice.

Bird JE, Giancarli MR, Kurihara T, Kowala MC, Valentine MT, Gitlitz PH, Pandya DG, French MH, Durham SK.

Kidney Int. 2000 Jan;57(1):129-36.

22.

Prospective identification of biologically active structures by topomer shape similarity searching.

Cramer RD, Poss MA, Hermsmeier MA, Caulfield TJ, Kowala MC, Valentine MT.

J Med Chem. 1999 Sep 23;42(19):3919-33.

PMID:
10508440
23.

Enhanced reduction of atherosclerosis in hamsters treated with pravastatin and captopril: ACE in atheromas provides cellular targets for captopril.

Kowala MC, Valentine M, Recce R, Beyer S, Goller N, Durham S, Aberg G.

J Cardiovasc Pharmacol. 1998 Jul;32(1):29-38.

PMID:
9676717
24.

Fibrinogen deficiency is compatible with the development of atherosclerosis in mice.

Xiao Q, Danton MJ, Witte DP, Kowala MC, Valentine MT, Degen JL.

J Clin Invest. 1998 Mar 1;101(5):1184-94.

25.

Plasminogen deficiency accelerates vessel wall disease in mice predisposed to atherosclerosis.

Xiao Q, Danton MJ, Witte DP, Kowala MC, Valentine MT, Bugge TH, Degen JL.

Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10335-40.

26.

Stimulation of activin A expression in rat aortic smooth muscle cells by thrombin and angiotensin II correlates with neointimal formation in vivo.

Pawlowski JE, Taylor DS, Valentine M, Hail ME, Ferrer P, Kowala MC, Molloy CJ.

J Clin Invest. 1997 Aug 1;100(3):639-48.

27.

The role of endothelin in the pathogenesis of atherosclerosis.

Kowala MC.

Adv Pharmacol. 1997;37:299-318. Review. No abstract available.

PMID:
8891105
28.

Selective blockade of the endothelin subtype A receptor decreases early atherosclerosis in hamsters fed cholesterol.

Kowala MC, Rose PM, Stein PD, Goller N, Recce R, Beyer S, Valentine M, Barton D, Durham SK.

Am J Pathol. 1995 Apr;146(4):819-26.

29.

Regression of early atherosclerosis in hyperlipidemic hamsters induced by fosinopril and captopril.

Kowala MC, Recce R, Beyer S, Aberg G.

J Cardiovasc Pharmacol. 1995 Feb;25(2):179-86.

PMID:
7752642
32.

Doxazosin and cholestyramine similarly decrease fatty streak formation in the aortic arch of hyperlipidemic hamsters.

Kowala MC, Nunnari JJ, Durham SK, Nicolosi RJ.

Atherosclerosis. 1991 Nov;91(1-2):35-49.

PMID:
1687433
33.

Effect of dietary fat saturation and cholesterol on LDL composition and metabolism. In vivo studies of receptor and nonreceptor-mediated catabolism of LDL in cebus monkeys.

Nicolosi RJ, Stucchi AF, Kowala MC, Hennessy LK, Hegsted DM, Schaefer EJ.

Arteriosclerosis. 1990 Jan-Feb;10(1):119-28.

PMID:
2297342
34.

Low density lipoprotein heterogeneity in the cebus monkey.

Puppione DL, Nicolosi RJ, Kowala MC, Schumaker VN.

J Lipid Res. 1989 May;30(5):641-50.

35.

Effects of prazosin on hemodynamics, hemostasis, and serum lipid and lipoprotein levels in normal and hypercholesterolemic monkeys.

Karge WH 3rd, Weiner EJ, Kowala MC, Graham RM, Nicolosi RJ.

Am J Med. 1989 Jan 23;86(1B):19-23.

PMID:
2913768
36.

Effect of doxazosin on plasma lipids and atherogenesis: a preliminary report.

Kowala MC, Nicolosi RJ.

J Cardiovasc Pharmacol. 1989;13 Suppl 2:S45-9; discussion S49.

PMID:
2471015
37.

Serum lipids, lipoproteins, hemodynamics, and hemostasis in doxazosin-treated monkeys.

Karge WH 3rd, Kowala MC, Weiner EJ, Nicolosi RJ.

J Cardiovasc Pharmacol. 1989;13 Suppl 2:S25-9; discussion S29-30.

PMID:
2471012
38.

Intimal changes in the aorta of prehypertensive rats.

Kowala MC, Cuénoud HF, Nicolosi R, Joris I, Majno G.

Exp Mol Pathol. 1988 Oct;49(2):171-84.

PMID:
3169204
39.

Altered adrenergic control in hypercholesterolemia.

Ohanian J, Nicolosi RJ, Vatner SF, Graham RM, Kowala MC, Young MA.

J Cardiovasc Pharmacol. 1987;10 Suppl 9:S11-5. Review.

PMID:
2447434
40.

Cellular changes during hypertension: a quantitative study of the rat aorta.

Kowala MC, Cuénoud HF, Joris I, Majno G.

Exp Mol Pathol. 1986 Dec;45(3):323-35.

PMID:
3792515

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