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Items: 1 to 50 of 196

1.

Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes.

Brown SA, Kovatchev BP, Raghinaru D, Lum JW, Buckingham BA, Kudva YC, Laffel LM, Levy CJ, Pinsker JE, Wadwa RP, Dassau E, Doyle FJ 3rd, Anderson SM, Church MM, Dadlani V, Ekhlaspour L, Forlenza GP, Isganaitis E, Lam DW, Kollman C, Beck RW; iDCL Trial Research Group.

N Engl J Med. 2019 Oct 16. doi: 10.1056/NEJMoa1907863. [Epub ahead of print]

PMID:
31618560
2.

Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range.

Battelino T, Danne T, Bergenstal RM, Amiel SA, Beck R, Biester T, Bosi E, Buckingham BA, Cefalu WT, Close KL, Cobelli C, Dassau E, DeVries JH, Donaghue KC, Dovc K, Doyle FJ 3rd, Garg S, Grunberger G, Heller S, Heinemann L, Hirsch IB, Hovorka R, Jia W, Kordonouri O, Kovatchev B, Kowalski A, Laffel L, Levine B, Mayorov A, Mathieu C, Murphy HR, Nimri R, Nørgaard K, Parkin CG, Renard E, Rodbard D, Saboo B, Schatz D, Stoner K, Urakami T, Weinzimer SA, Phillip M.

Diabetes Care. 2019 Aug;42(8):1593-1603. doi: 10.2337/dci19-0028. Epub 2019 Jun 8. Review.

3.

A Century of Diabetes Technology: Signals, Models, and Artificial Pancreas Control.

Kovatchev B.

Trends Endocrinol Metab. 2019 Jul;30(7):432-444. doi: 10.1016/j.tem.2019.04.008. Epub 2019 May 28. Review.

PMID:
31151733
4.

Closed loop control in adolescents and children during winter sports: Use of the Tandem Control-IQ AP system.

Ekhlaspour L, Forlenza GP, Chernavvsky D, Maahs DM, Wadwa RP, Deboer MD, Messer LH, Town M, Pinnata J, Kruse G, Kovatchev BP, Buckingham BA, Breton MD.

Pediatr Diabetes. 2019 Sep;20(6):759-768. doi: 10.1111/pedi.12867. Epub 2019 May 23.

5.

Hybrid Closed-Loop Control Is Safe and Effective for People with Type 1 Diabetes Who Are at Moderate to High Risk for Hypoglycemia.

Anderson SM, Buckingham BA, Breton MD, Robic JL, Barnett CL, Wakeman CA, Oliveri MC, Brown SA, Ly TT, Clinton PK, Hsu LJ, Kingman RS, Norlander LM, Loebner SE, Reuschel-DiVirglio S, Kovatchev BP.

Diabetes Technol Ther. 2019 Jun;21(6):356-363. doi: 10.1089/dia.2019.0018. Epub 2019 May 16.

PMID:
31095423
6.

Beyond HbA1c : using continuous glucose monitoring metrics to enhance interpretation of treatment effect and improve clinical decision-making.

Brown SA, Basu A, Kovatchev BP.

Diabet Med. 2019 Jun;36(6):679-687. doi: 10.1111/dme.13944. Epub 2019 Apr 5. Review.

PMID:
30848545
7.

Glycemic Variability: Risk Factors, Assessment, and Control.

Kovatchev B.

J Diabetes Sci Technol. 2019 Jul;13(4):627-635. doi: 10.1177/1932296819826111. Epub 2019 Jan 29.

PMID:
30694076
8.

The International Diabetes Closed-Loop Study: Testing Artificial Pancreas Component Interoperability.

Anderson SM, Dassau E, Raghinaru D, Lum J, Brown SA, Pinsker JE, Church MM, Levy C, Lam D, Kudva YC, Buckingham B, Forlenza GP, Wadwa RP, Laffel L, Doyle FJ 3rd, DeVries JH, Renard E, Cobelli C, Boscari F, Del Favero S, Kovatchev BP.

Diabetes Technol Ther. 2019 Feb;21(2):73-80. doi: 10.1089/dia.2018.0308. Epub 2019 Jan 16.

PMID:
30649925
9.

Insulin glargine/lixisenatide fixed-ratio combination improves glycaemic variability and control without increasing hypoglycaemia.

Aronson R, Umpierrez G, Stager W, Kovatchev B.

Diabetes Obes Metab. 2019 Mar;21(3):726-731. doi: 10.1111/dom.13580. Epub 2018 Dec 10.

10.

First Look at Control-IQ: A New-Generation Automated Insulin Delivery System.

Brown S, Raghinaru D, Emory E, Kovatchev B.

Diabetes Care. 2018 Dec;41(12):2634-2636. doi: 10.2337/dc18-1249. Epub 2018 Oct 10.

PMID:
30305346
11.

Diabetes Technology: Monitoring, Analytics, and Optimal Control.

Kovatchev B.

Cold Spring Harb Perspect Med. 2019 Jun 3;9(6). pii: a034389. doi: 10.1101/cshperspect.a034389. Review.

PMID:
30126835
12.

Continuous Glucose Monitoring and Insulin Informed Advisory System with Automated Titration and Dosing of Insulin Reduces Glucose Variability in Type 1 Diabetes Mellitus.

Breton MD, Patek SD, Lv D, Schertz E, Robic J, Pinnata J, Kollar L, Barnett C, Wakeman C, Oliveri M, Fabris C, Chernavvsky D, Kovatchev BP, Anderson SM.

Diabetes Technol Ther. 2018 Aug;20(8):531-540. doi: 10.1089/dia.2018.0079. Epub 2018 Jul 6.

13.

Investigation of the Accuracy of 18 Marketed Blood Glucose Monitors.

Klonoff DC, Parkes JL, Kovatchev BP, Kerr D, Bevier WC, Brazg RL, Christiansen M, Bailey TS, Nichols JH, Kohn MA.

Diabetes Care. 2018 Aug;41(8):1681-1688. doi: 10.2337/dc17-1960. Epub 2018 Jun 13.

PMID:
29898901
14.

The UVA/Padova Type 1 Diabetes Simulator Goes From Single Meal to Single Day.

Visentin R, Campos-Náñez E, Schiavon M, Lv D, Vettoretti M, Breton M, Kovatchev BP, Dalla Man C, Cobelli C.

J Diabetes Sci Technol. 2018 Mar;12(2):273-281. doi: 10.1177/1932296818757747. Epub 2018 Feb 16.

15.

The artificial pancreas in 2017: The year of transition from research to clinical practice.

Kovatchev B.

Nat Rev Endocrinol. 2018 Feb;14(2):74-76. doi: 10.1038/nrendo.2017.170. Epub 2017 Dec 22. Review. No abstract available.

PMID:
29286043
16.

International Consensus on Use of Continuous Glucose Monitoring.

Danne T, Nimri R, Battelino T, Bergenstal RM, Close KL, DeVries JH, Garg S, Heinemann L, Hirsch I, Amiel SA, Beck R, Bosi E, Buckingham B, Cobelli C, Dassau E, Doyle FJ 3rd, Heller S, Hovorka R, Jia W, Jones T, Kordonouri O, Kovatchev B, Kowalski A, Laffel L, Maahs D, Murphy HR, Nørgaard K, Parkin CG, Renard E, Saboo B, Scharf M, Tamborlane WV, Weinzimer SA, Phillip M.

Diabetes Care. 2017 Dec;40(12):1631-1640. doi: 10.2337/dc17-1600. Review.

17.

Twelve-Week 24/7 Ambulatory Artificial Pancreas With Weekly Adaptation of Insulin Delivery Settings: Effect on Hemoglobin A1c and Hypoglycemia.

Dassau E, Pinsker JE, Kudva YC, Brown SA, Gondhalekar R, Dalla Man C, Patek S, Schiavon M, Dadlani V, Dasanayake I, Church MM, Carter RE, Bevier WC, Huyett LM, Hughes J, Anderson S, Lv D, Schertz E, Emory E, McCrady-Spitzer SK, Jean T, Bradley PK, Hinshaw L, Laguna Sanz AJ, Basu A, Kovatchev B, Cobelli C, Doyle FJ 3rd.

Diabetes Care. 2017 Dec;40(12):1719-1726. doi: 10.2337/dc17-1188. Epub 2017 Oct 13.

18.

Recent Exposure to Hypoglycemia Increases Glucose Variability Following a Hyper/Hypoglycemic Metabolic Challenge in T1D.

Fabris C, Farhy LS, Anderson SM, Nass RM, Kovatchev BP, Breton MD.

J Diabetes Sci Technol. 2018 Mar;12(2):311-317. doi: 10.1177/1932296817729392. Epub 2017 Sep 25.

19.

Closed-Loop Control During Intense Prolonged Outdoor Exercise in Adolescents With Type 1 Diabetes: The Artificial Pancreas Ski Study.

Breton MD, Cherñavvsky DR, Forlenza GP, DeBoer MD, Robic J, Wadwa RP, Messer LH, Kovatchev BP, Maahs DM.

Diabetes Care. 2017 Dec;40(12):1644-1650. doi: 10.2337/dc17-0883. Epub 2017 Aug 30.

20.

Overnight Closed-Loop Control Improves Glycemic Control in a Multicenter Study of Adults With Type 1 Diabetes.

Brown SA, Breton MD, Anderson SM, Kollar L, Keith-Hynes P, Levy CJ, Lam DW, Levister C, Baysal N, Kudva YC, Basu A, Dadlani V, Hinshaw L, McCrady-Spitzer S, Bruttomesso D, Visentin R, Galasso S, Del Favero S, Leal Y, Boscari F, Avogaro A, Cobelli C, Kovatchev BP.

J Clin Endocrinol Metab. 2017 Oct 1;102(10):3674-3682. doi: 10.1210/jc.2017-00556.

21.

Future of Automated Insulin Delivery Systems.

Castle JR, DeVries JH, Kovatchev B.

Diabetes Technol Ther. 2017 Jun;19(S3):S67-S72. doi: 10.1089/dia.2017.0012. Review.

22.

In silico assessment of biomedical products: The conundrum of rare but not so rare events in two case studies.

Viceconti M, Cobelli C, Haddad T, Himes A, Kovatchev B, Palmer M.

Proc Inst Mech Eng H. 2017 May;231(5):455-466. doi: 10.1177/0954411917702931.

23.

Performance of an Artificial Pancreas System for Young Children with Type 1 Diabetes.

DeBoer MD, Breton MD, Wakeman C, Schertz EM, Emory EG, Robic JL, Kollar LL, Kovatchev BP, Cherñavvsky DR.

Diabetes Technol Ther. 2017 May;19(5):293-298. doi: 10.1089/dia.2016.0424. Epub 2017 Apr 20.

PMID:
28426239
24.

Metrics for glycaemic control - from HbA1c to continuous glucose monitoring.

Kovatchev BP.

Nat Rev Endocrinol. 2017 Jul;13(7):425-436. doi: 10.1038/nrendo.2017.3. Epub 2017 Mar 17. Review.

PMID:
28304392
25.

Lixisenatide reduces glycaemic variability in insulin-treated patients with type 2 diabetes.

Umpierrez GE, O'Neal D, DiGenio A, Goldenberg R, Hernandez-Triana E, Lin J, Park CY, Renard E, Kovatchev B.

Diabetes Obes Metab. 2017 Sep;19(9):1317-1321. doi: 10.1111/dom.12930. Epub 2017 May 5.

PMID:
28256054
26.

Feasibility of Long-Term Closed-Loop Control: A Multicenter 6-Month Trial of 24/7 Automated Insulin Delivery.

Kovatchev B, Cheng P, Anderson SM, Pinsker JE, Boscari F, Buckingham BA, Doyle FJ 3rd, Hood KK, Brown SA, Breton MD, Chernavvsky D, Bevier WC, Bradley PK, Bruttomesso D, Del Favero S, Calore R, Cobelli C, Avogaro A, Ly TT, Shanmugham S, Dassau E, Kollman C, Lum JW, Beck RW.

Diabetes Technol Ther. 2017 Jan;19(1):18-24. doi: 10.1089/dia.2016.0333. Epub 2016 Dec 16.

PMID:
27982707
27.

Impact of Meal Constituents on Artificial Pancreas Algorithms.

Campos-Náñez E, Kovatchev BP.

Diabetes Technol Ther. 2016 Oct;18(10):607-609. No abstract available.

28.

Heart rate informed artificial pancreas system enhances glycemic control during exercise in adolescents with T1D.

DeBoer MD, Cherñavvsky DR, Topchyan K, Kovatchev BP, Francis GL, Breton MD.

Pediatr Diabetes. 2017 Nov;18(7):540-546. doi: 10.1111/pedi.12454. Epub 2016 Oct 13.

PMID:
27734563
29.

Response to Comment on Kovatchev and Cobelli. Glucose Variability: Timing, Risk Analysis, and Relationship to Hypoglycemia in Diabetes. Diabetes Care 2016;39:502-510.

Kovatchev B, Cobelli C.

Diabetes Care. 2016 Sep;39(9):e157-8. doi: 10.2337/dci16-0019. No abstract available.

PMID:
27555633
30.

Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report.

Maahs DM, Buckingham BA, Castle JR, Cinar A, Damiano ER, Dassau E, DeVries JH, Doyle FJ 3rd, Griffen SC, Haidar A, Heinemann L, Hovorka R, Jones TW, Kollman C, Kovatchev B, Levy BL, Nimri R, O'Neal DN, Philip M, Renard E, Russell SJ, Weinzimer SA, Zisser H, Lum JW.

Diabetes Care. 2016 Jul;39(7):1175-9. doi: 10.2337/dc15-2716. Review.

31.

The Artificial Pancreas in 2016: A Digital Treatment Ecosystem for Diabetes.

Kovatchev B, Tamborlane WV, Cefalu WT, Cobelli C.

Diabetes Care. 2016 Jul;39(7):1123-6. doi: 10.2337/dc16-0824. No abstract available.

32.

Glucose Variability: Timing, Risk Analysis, and Relationship to Hypoglycemia in Diabetes.

Kovatchev B, Cobelli C.

Diabetes Care. 2016 Apr;39(4):502-10. doi: 10.2337/dc15-2035.

33.

Day-and-Night Closed-Loop Glucose Control in Patients With Type 1 Diabetes Under Free-Living Conditions: Results of a Single-Arm 1-Month Experience Compared With a Previously Reported Feasibility Study of Evening and Night at Home.

Renard E, Farret A, Kropff J, Bruttomesso D, Messori M, Place J, Visentin R, Calore R, Toffanin C, Di Palma F, Lanzola G, Magni P, Boscari F, Galasso S, Avogaro A, Keith-Hynes P, Kovatchev B, Del Favero S, Cobelli C, Magni L, DeVries JH; AP@home Consortium.

Diabetes Care. 2016 Jul;39(7):1151-60. doi: 10.2337/dc16-0008. Epub 2016 May 5.

PMID:
27208331
34.

Multinational Home Use of Closed-Loop Control Is Safe and Effective.

Anderson SM, Raghinaru D, Pinsker JE, Boscari F, Renard E, Buckingham BA, Nimri R, Doyle FJ 3rd, Brown SA, Keith-Hynes P, Breton MD, Chernavvsky D, Bevier WC, Bradley PK, Bruttomesso D, Del Favero S, Calore R, Cobelli C, Avogaro A, Farret A, Place J, Ly TT, Shanmugham S, Phillip M, Dassau E, Dasanayake IS, Kollman C, Lum JW, Beck RW, Kovatchev B; Control to Range Study Group.

Diabetes Care. 2016 Jul;39(7):1143-50. doi: 10.2337/dc15-2468. Epub 2016 Apr 13.

35.

Accuracy of Continuous Glucose Monitoring in Patients After Total Pancreatectomy with Islet Autotransplantation.

Forlenza GP, Nathan BM, Moran A, Dunn TB, Beilman GJ, Pruett TL, Kovatchev BP, Bellin MD.

Diabetes Technol Ther. 2016 Aug;18(8):455-63. doi: 10.1089/dia.2015.0405. Epub 2016 Apr 22.

36.

How well do glucose variability measures predict patient glycaemic outcomes during treatment intensification in type 2 diabetes?

Inzucchi SE, Umpierrez G, DiGenio A, Zhou R, Kovatchev B.

Diabetes Res Clin Pract. 2015 Nov;110(2):234-40.

PMID:
27049155
37.

Is Psychological Stress a Factor for Incorporation Into Future Closed-Loop Systems?

Gonder-Frederick LA, Grabman JH, Kovatchev B, Brown SA, Patek S, Basu A, Pinsker JE, Kudva YC, Wakeman CA, Dassau E, Cobelli C, Zisser HC, Doyle FJ 3rd.

J Diabetes Sci Technol. 2016 May 3;10(3):640-6. doi: 10.1177/1932296816635199. Print 2016 May.

38.

Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement.

Bartlett ST, Markmann JF, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, OʼConnell P, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Kovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T.

Transplantation. 2016 Feb;100 Suppl 2:S1-44. doi: 10.1097/TP.0000000000001055. No abstract available.

39.

Hemoglobin A1c and Self-Monitored Average Glucose: Validation of the Dynamical Tracking eA1c Algorithm in Type 1 Diabetes.

Kovatchev BP, Breton MD.

J Diabetes Sci Technol. 2015 Nov 9;10(2):330-5. doi: 10.1177/1932296815608870.

40.

Development of the Diabetes Technology Society Blood Glucose Monitor System Surveillance Protocol.

Klonoff DC, Lias C, Beck S, Parkes JL, Kovatchev B, Vigersky RA, Arreaza-Rubin G, Burk RD, Kowalski A, Little R, Nichols J, Petersen M, Rawlings K, Sacks DB, Sampson E, Scott S, Seley JJ, Slingerland R, Vesper HW.

J Diabetes Sci Technol. 2016 May 3;10(3):697-707. doi: 10.1177/1932296815614587. Print 2016 May.

41.

2 month evening and night closed-loop glucose control in patients with type 1 diabetes under free-living conditions: a randomised crossover trial.

Kropff J, Del Favero S, Place J, Toffanin C, Visentin R, Monaro M, Messori M, Di Palma F, Lanzola G, Farret A, Boscari F, Galasso S, Magni P, Avogaro A, Keith-Hynes P, Kovatchev BP, Bruttomesso D, Cobelli C, DeVries JH, Renard E, Magni L; AP@home consortium.

Lancet Diabetes Endocrinol. 2015 Dec;3(12):939-47. doi: 10.1016/S2213-8587(15)00335-6. Epub 2015 Sep 30.

PMID:
26432775
42.

Measures of Risk and Glucose Variability in Adults Versus Youths.

Kovatchev BP.

Diabetes Technol Ther. 2015 Nov;17(11):766-9. doi: 10.1089/dia.2015.0276. Epub 2015 Sep 8. No abstract available.

43.

Adjustment of Open-Loop Settings to Improve Closed-Loop Results in Type 1 Diabetes: A Multicenter Randomized Trial.

Dassau E, Brown SA, Basu A, Pinsker JE, Kudva YC, Gondhalekar R, Patek S, Lv D, Schiavon M, Lee JB, Dalla Man C, Hinshaw L, Castorino K, Mallad A, Dadlani V, McCrady-Spitzer SK, McElwee-Malloy M, Wakeman CA, Bevier WC, Bradley PK, Kovatchev B, Cobelli C, Zisser HC, Doyle FJ 3rd.

J Clin Endocrinol Metab. 2015 Oct;100(10):3878-86. doi: 10.1210/jc.2015-2081. Epub 2015 Jul 23.

44.

Sensitivity of the Predictive Hypoglycemia Minimizer System to the Algorithm Aggressiveness Factor.

Finan DA, Dassau E, Breton MD, Patek SD, McCann TW Jr, Kovatchev BP, Doyle FJ 3rd, Levy BL, Venugopalan R.

J Diabetes Sci Technol. 2015 Jun 30;10(1):104-10. doi: 10.1177/1932296815593292.

45.

Sensitivity of Traditional and Risk-Based Glycemic Variability Measures to the Effect of Glucose-Lowering Treatment in Type 2 Diabetes Mellitus.

Kovatchev B, Umpierrez G, DiGenio A, Zhou R, Inzucchi SE.

J Diabetes Sci Technol. 2015 Jun 15;9(6):1227-35. doi: 10.1177/1932296815587014.

46.

Hypoglycemia Reduction and Accuracy of Continuous Glucose Monitoring.

Kovatchev BP.

Diabetes Technol Ther. 2015 Aug;17(8):530-3. doi: 10.1089/dia.2015.0144. Epub 2015 May 15. No abstract available.

47.

Pharmacokinetic Model of the Transport of Fast-Acting Insulin From the Subcutaneous and Intradermal Spaces to Blood.

Lv D, Kulkarni SD, Chan A, Keith S, Pettis R, Kovatchev BP, Farhi LS, Breton MD.

J Diabetes Sci Technol. 2015 Jul;9(4):831-40. doi: 10.1177/1932296815573864. Epub 2015 Mar 9.

48.

How well do glucose variability measures predict patient glycaemic outcomes during treatment intensification in type 2 diabetes?

Inzucchi SE, Umpierrez G, DiGenio A, Zhou R, Kovatchev B.

Diabetes Res Clin Pract. 2015 Apr;108(1):179-86. doi: 10.1016/j.diabres.2014.12.020. Epub 2015 Jan 21. Corrected and republished in: Diabetes Res Clin Pract. 2015 Nov;110(2):234-40.

PMID:
25661664
49.

Multicenter outpatient dinner/overnight reduction of hypoglycemia and increased time of glucose in target with a wearable artificial pancreas using modular model predictive control in adults with type 1 diabetes.

Del Favero S, Place J, Kropff J, Messori M, Keith-Hynes P, Visentin R, Monaro M, Galasso S, Boscari F, Toffanin C, Di Palma F, Lanzola G, Scarpellini S, Farret A, Kovatchev B, Avogaro A, Bruttomesso D, Magni L, DeVries JH, Cobelli C, Renard E; AP@home Consortium.

Diabetes Obes Metab. 2015 May;17(5):468-76. doi: 10.1111/dom.12440. Epub 2015 Feb 16.

PMID:
25600304
50.

Multinight "bedside" closed-loop control for patients with type 1 diabetes.

Brown SA, Kovatchev BP, Breton MD, Anderson SM, Keith-Hynes P, Patek SD, Jiang B, Ben Brahim N, Vereshchetin P, Bruttomesso D, Avogaro A, Del Favero S, Boscari F, Galasso S, Visentin R, Monaro M, Cobelli C.

Diabetes Technol Ther. 2015 Mar;17(3):203-9. doi: 10.1089/dia.2014.0259. Epub 2015 Jan 16.

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