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Items: 1 to 50 of 80

1.

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment.

Parrini M, Meissl K, Ola MJ, Lederer T, Puga A, Wienerroither S, Kovarik P, Decker T, Müller M, Strobl B.

Front Immunol. 2018 Dec 6;9:2879. doi: 10.3389/fimmu.2018.02879. eCollection 2018.

2.

Competition of Candida glabrata against Lactobacillus is Hog1 dependent.

Beyer R, Jandric Z, Zutz C, Gregori C, Willinger B, Jacobsen ID, Kovarik P, Strauss J, Schüller C.

Cell Microbiol. 2018 Dec;20(12):e12943. doi: 10.1111/cmi.12943. Epub 2018 Sep 7.

3.

Pancreatic Collision Tumor of Ductal Adenocarcinoma and Neuroendocrine Tumor.

Wang Y, Gandhi S, Basu A, Ijeli A, Kovarik P, Sekosan M, Demetria M.

ACG Case Rep J. 2018 May 23;5:e39. doi: 10.14309/crj.2018.39. eCollection 2018.

4.

The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification.

Sedlyarov V, Eichner R, Girardi E, Essletzbichler P, Goldmann U, Nunes-Hasler P, Srndic I, Moskovskich A, Heinz LX, Kartnig F, Bigenzahn JW, Rebsamen M, Kovarik P, Demaurex N, Superti-Furga G.

Cell Host Microbe. 2018 Jun 13;23(6):766-774.e5. doi: 10.1016/j.chom.2018.04.013. Epub 2018 May 17.

5.

Iatrogenic T-Cell Lymphoma with Associated Hemophagocytic Lymphohistiocyotsis in a Patient with Long-Standing Rheumatoid Arthritis.

Andrade XA, Fuentes HE, Oramas DM, Mann H, Kovarik P.

Case Rep Hematol. 2018 Jan 11;2018:8097965. doi: 10.1155/2018/8097965. eCollection 2018.

6.

Primary Liver Diffuse Large B-Cell Lymphoma following Complete Response for Hepatitis C Infection after Direct Antiviral Therapy.

Andrade XA, Paz LH, Nassar M, Oramas DM, Fuentes HE, Kovarik P, Mishra S, Singh A.

Acta Haematol. 2018;139(2):77-80. doi: 10.1159/000484653. Epub 2018 Jan 26.

PMID:
29393087
7.

Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection.

Ivin M, Dumigan A, de Vasconcelos FN, Ebner F, Borroni M, Kavirayani A, Przybyszewska KN, Ingram RJ, Lienenklaus S, Kalinke U, Stoiber D, Bengoechea JA, Kovarik P.

PLoS Pathog. 2017 Nov 7;13(11):e1006696. doi: 10.1371/journal.ppat.1006696. eCollection 2017 Nov.

8.

Correction: The Influence of Programmed Cell Death in Myeloid Cells on Host Resilience to Infection with Legionella pneumophila or Streptococcus pyogenes.

Gamradt P, Xu Y, Gratz N, Duncan K, Kobzik L, Högler S, Kovarik P, Decker T, Jamieson AM.

PLoS Pathog. 2017 Aug 30;13(8):e1006591. doi: 10.1371/journal.ppat.1006591. eCollection 2017 Aug.

9.

The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection.

Ebner F, Sedlyarov V, Tasciyan S, Ivin M, Kratochvill F, Gratz N, Kenner L, Villunger A, Sixt M, Kovarik P.

J Clin Invest. 2017 Jun 1;127(6):2051-2065. doi: 10.1172/JCI80631. Epub 2017 May 15.

10.

HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.

Lang M, Berry D, Passecker K, Mesteri I, Bhuju S, Ebner F, Sedlyarov V, Evstatiev R, Dammann K, Loy A, Kuzyk O, Kovarik P, Khare V, Beibel M, Roma G, Meisner-Kober N, Gasche C.

Cancer Res. 2017 May 1;77(9):2424-2438. doi: 10.1158/0008-5472.CAN-15-1726. Epub 2017 Feb 20.

11.

Type I Interferons in Bacterial Infections: A Balancing Act.

Kovarik P, Castiglia V, Ivin M, Ebner F.

Front Immunol. 2016 Dec 26;7:652. doi: 10.3389/fimmu.2016.00652. eCollection 2016. Review.

12.

The Influence of Programmed Cell Death in Myeloid Cells on Host Resilience to Infection with Legionella pneumophila or Streptococcus pyogenes.

Gamradt P, Xu Y, Gratz N, Duncan K, Kobzik L, Högler S, Kovarik P, Decker T, Jamieson AM.

PLoS Pathog. 2016 Dec 14;12(12):e1006032. doi: 10.1371/journal.ppat.1006032. eCollection 2016 Dec. Erratum in: PLoS Pathog. 2017 Aug 30;13(8):e1006591.

13.

Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution.

Sedlyarov V, Fallmann J, Ebner F, Huemer J, Sneezum L, Ivin M, Kreiner K, Tanzer A, Vogl C, Hofacker I, Kovarik P.

Mol Syst Biol. 2016 May 13;12(5):868. doi: 10.15252/msb.20156628.

14.

Post-transplant extranodal NK/T-cell lymphoma, nasal type with cutaneous and pulmonary involvement.

Acosta AM, Alagiozian-Angelova V, Kovarik P, Sekosan M.

Pathology. 2016 Jun;48(4):380-3. doi: 10.1016/j.pathol.2016.03.011. Epub 2016 Apr 26. No abstract available.

PMID:
27130835
15.

Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue.

Castiglia V, Piersigilli A, Ebner F, Janos M, Goldmann O, Damböck U, Kröger A, Weiss S, Knapp S, Jamieson AM, Kirschning C, Kalinke U, Strobl B, Müller M, Stoiber D, Lienenklaus S, Kovarik P.

Cell Host Microbe. 2016 Mar 9;19(3):375-87. doi: 10.1016/j.chom.2016.02.003.

16.

AREsite2: an enhanced database for the comprehensive investigation of AU/GU/U-rich elements.

Fallmann J, Sedlyarov V, Tanzer A, Kovarik P, Hofacker IL.

Nucleic Acids Res. 2016 Jan 4;44(D1):D90-5. doi: 10.1093/nar/gkv1238. Epub 2015 Nov 23.

17.

Posttranscriptional regulation of cytokine expression.

Kovarik P, Ebner F, Sedlyarov V.

Cytokine. 2017 Jan;89:21-26. doi: 10.1016/j.cyto.2015.11.007. Epub 2015 Nov 14. Review.

PMID:
26586165
18.

Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.

Kratochvill F, Gratz N, Qualls JE, Van De Velde LA, Chi H, Kovarik P, Murray PJ.

Cancer Res. 2015 Aug 1;75(15):3054-64. doi: 10.1158/0008-5472.CAN-15-0205. Epub 2015 Jul 16.

19.

Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.

Fieber C, Janos M, Koestler T, Gratz N, Li XD, Castiglia V, Aberle M, Sauert M, Wegner M, Alexopoulou L, Kirschning CJ, Chen ZJ, von Haeseler A, Kovarik P.

PLoS One. 2015 Mar 10;10(3):e0119727. doi: 10.1371/journal.pone.0119727. eCollection 2015.

20.

Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription.

Wiesauer I, Gaumannmüller C, Steinparzer I, Strobl B, Kovarik P.

Mol Cell Biol. 2015 Feb;35(4):716-27. doi: 10.1128/MCB.01097-14. Epub 2014 Dec 15.

21.

Responses of innate immune cells to group A Streptococcus.

Fieber C, Kovarik P.

Front Cell Infect Microbiol. 2014 Oct 2;4:140. doi: 10.3389/fcimb.2014.00140. eCollection 2014. Review.

22.

Hypotension associated with advanced hodgkin lymphoma.

Mangla A, Dang G, Hamad H, Mohajer R, Catchatourian R, Kovarik P.

Hematol Rep. 2014 Sep 29;6(3):5572. doi: 10.4081/hr.2014.5572. eCollection 2014 Aug 26.

23.

The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type.

Dinis M, Plainvert C, Kovarik P, Longo M, Fouet A, Poyart C.

PLoS One. 2014 Jul 3;9(7):e101464. doi: 10.1371/journal.pone.0101464. eCollection 2014.

24.

CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.

Bancerek J, Poss ZC, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dölken L, Strobl B, Müller M, Taatjes DJ, Kovarik P.

Immunity. 2013 Feb 21;38(2):250-62. doi: 10.1016/j.immuni.2012.10.017. Epub 2013 Jan 24.

25.

Tristetraprolin-driven regulatory circuit controls quality and timing of mRNA decay in inflammation.

Kratochvill F, Machacek C, Vogl C, Ebner F, Sedlyarov V, Gruber AR, Hartweger H, Vielnascher R, Karaghiosoff M, Rülicke T, Müller M, Hofacker I, Lang R, Kovarik P.

Mol Syst Biol. 2011 Dec 20;7:560. doi: 10.1038/msb.2011.93.

26.

Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection.

Gratz N, Hartweger H, Matt U, Kratochvill F, Janos M, Sigel S, Drobits B, Li XD, Knapp S, Kovarik P.

PLoS Pathog. 2011 May;7(5):e1001345. doi: 10.1371/journal.ppat.1001345. Epub 2011 May 19.

27.

Regulation of Candida glabrata oxidative stress resistance is adapted to host environment.

Roetzer A, Klopf E, Gratz N, Marcet-Houben M, Hiller E, Rupp S, Gabaldón T, Kovarik P, Schüller C.

FEBS Lett. 2011 Jan 21;585(2):319-27. doi: 10.1016/j.febslet.2010.12.006. Epub 2010 Dec 13.

28.

AREsite: a database for the comprehensive investigation of AU-rich elements.

Gruber AR, Fallmann J, Kratochvill F, Kovarik P, Hofacker IL.

Nucleic Acids Res. 2011 Jan;39(Database issue):D66-9. doi: 10.1093/nar/gkq990. Epub 2010 Nov 11.

29.

Tyrosine kinase 2 controls IL-1ß production at the translational level.

Radwan M, Stiefvater R, Grunert T, Sharif O, Miller I, Marchetti-Deschmann M, Allmaier G, Gemeiner M, Knapp S, Kovarik P, Müller M, Strobl B.

J Immunol. 2010 Sep 15;185(6):3544-53. doi: 10.4049/jimmunol.0904000. Epub 2010 Aug 16.

30.

Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes.

Vogl C, Flatt T, Fuhrmann B, Hofmann E, Wallner B, Stiefvater R, Kovarik P, Strobl B, Müller M.

BMC Genomics. 2010 Mar 25;11:199. doi: 10.1186/1471-2164-11-199.

31.

Autophagy supports Candida glabrata survival during phagocytosis.

Roetzer A, Gratz N, Kovarik P, Schüller C.

Cell Microbiol. 2010 Feb;12(2):199-216. doi: 10.1111/j.1462-5822.2009.01391.x. Epub 2009 Oct 6.

32.

Tristetraprolin is required for full anti-inflammatory response of murine macrophages to IL-10.

Schaljo B, Kratochvill F, Gratz N, Sadzak I, Sauer I, Hammer M, Vogl C, Strobl B, Müller M, Blackshear PJ, Poli V, Lang R, Murray PJ, Kovarik P.

J Immunol. 2009 Jul 15;183(2):1197-206. doi: 10.4049/jimmunol.0803883. Epub 2009 Jun 19.

33.

Recruitment of Stat1 to chromatin is required for interferon-induced serine phosphorylation of Stat1 transactivation domain.

Sadzak I, Schiff M, Gattermeier I, Glinitzer R, Sauer I, Saalmüller A, Yang E, Schaljo B, Kovarik P.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8944-9. doi: 10.1073/pnas.0801794105. Epub 2008 Jun 23.

34.

Group A streptococcus activates type I interferon production and MyD88-dependent signaling without involvement of TLR2, TLR4, and TLR9.

Gratz N, Siller M, Schaljo B, Pirzada ZA, Gattermeier I, Vojtek I, Kirschning CJ, Wagner H, Akira S, Charpentier E, Kovarik P.

J Biol Chem. 2008 Jul 18;283(29):19879-87. doi: 10.1074/jbc.M802848200. Epub 2008 May 14.

35.

Molecular mechanisms of the anti-inflammatory functions of interferons.

Kovarik P, Sauer I, Schaljo B.

Immunobiology. 2007;212(9-10):895-901. Epub 2007 Nov 8. Review.

36.

Nine-amino-acid transactivation domain: establishment and prediction utilities.

Piskacek S, Gregor M, Nemethova M, Grabner M, Kovarik P, Piskacek M.

Genomics. 2007 Jun;89(6):756-68. Epub 2007 Apr 30.

38.

Polymorphic lymphoid proliferation presenting as ileocecal intussusception.

Wang X, Nathan S, Catchatourian R, Richter H 3rd, Kovarik P.

Ann Hematol. 2007 Jun;86(6):453-4. Epub 2007 Jan 10. No abstract available.

PMID:
17216223
39.

Panniculitis-like T-cell lymphoma with an unusual clinical presentation.

Majeed M, Kovarik P, Puttaswamy S, Borkowsky S.

Leuk Lymphoma. 2006 Aug;47(8):1696-8. No abstract available.

PMID:
16966291
40.

Design considerations for high speed quantitative mass spectrometry with MALDI ionization.

Corr JJ, Kovarik P, Schneider BB, Hendrikse J, Loboda A, Covey TR.

J Am Soc Mass Spectrom. 2006 Aug;17(8):1129-1141. doi: 10.1016/j.jasms.2006.04.026. Epub 2006 Jun 5.

41.

Acute splenic sequestration crisis in an adult with sickle beta-thalassemia.

Koduri PR, Kovarik P.

Ann Hematol. 2006 Sep;85(9):633-5. Epub 2006 May 17. Review.

PMID:
16705454
42.

Interferons limit inflammatory responses by induction of tristetraprolin.

Sauer I, Schaljo B, Vogl C, Gattermeier I, Kolbe T, Müller M, Blackshear PJ, Kovarik P.

Blood. 2006 Jun 15;107(12):4790-7. Epub 2006 Mar 2.

43.

Characterization and performance of MALDI on a triple quadrupole mass spectrometer for analysis and quantification of small molecules.

Gobey J, Cole M, Janiszewski J, Covey T, Chau T, Kovarik P, Corr J.

Anal Chem. 2005 Sep 1;77(17):5643-54.

PMID:
16131077
44.

Capillary-scale frontal affinity chromatography/MALDI tandem mass spectrometry using protein-doped monolithic silica columns.

Kovarik P, Hodgson RJ, Covey T, Brook MA, Brennan JD.

Anal Chem. 2005 May 15;77(10):3340-50.

PMID:
15889927
45.

Perinucleolar compartment prevalence has an independent prognostic value for breast cancer.

Kamath RV, Thor AD, Wang C, Edgerton SM, Slusarczyk A, Leary DJ, Wang J, Wiley EL, Jovanovic B, Wu Q, Nayar R, Kovarik P, Shi F, Huang S.

Cancer Res. 2005 Jan 1;65(1):246-53.

46.

Quantitative analysis of small pharmaceutical drugs using a high repetition rate laser matrix-assisted laser/desorption ionization source.

Hatsis P, Brombacher S, Corr J, Kovarik P, Volmer DA.

Rapid Commun Mass Spectrom. 2003;17(20):2303-9.

PMID:
14558130
47.

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.

Karaghiosoff M, Steinborn R, Kovarik P, Kriegshäuser G, Baccarini M, Donabauer B, Reichart U, Kolbe T, Bogdan C, Leanderson T, Levy D, Decker T, Müller M.

Nat Immunol. 2003 May;4(5):471-7. Epub 2003 Apr 7.

PMID:
12679810
48.

Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons.

Pilz A, Ramsauer K, Heidari H, Leitges M, Kovarik P, Decker T.

EMBO Rep. 2003 Apr;4(4):368-73. Epub 2003 Mar 21.

49.

p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation.

Ramsauer K, Sadzak I, Porras A, Pilz A, Nebreda AR, Decker T, Kovarik P.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12859-64. Epub 2002 Sep 13.

50.

IFNs and STATs in innate immunity to microorganisms.

Decker T, Stockinger S, Karaghiosoff M, Müller M, Kovarik P.

J Clin Invest. 2002 May;109(10):1271-7. Review. No abstract available.

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