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Items: 1 to 50 of 292

1.

Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease.

Llorens F, Villar-Piqué A, Hermann P, Schmitz M, Calero O, Stehmann C, Sarros S, Moda F, Ferrer I, Poleggi A, Pocchiari M, Catania M, Klotz S, O'Regan C, Brett F, Heffernan J, Ladogana A, Collins SJ, Calero M, Kovacs GG, Zerr I.

Biomolecules. 2020 Feb 12;10(2). pii: E290. doi: 10.3390/biom10020290.

2.

CpG and non-CpG Presenilin1 methylation pattern in course of neurodevelopment and neurodegeneration is associated with gene expression in human and murine brain.

Monti N, Cavallaro RA, Stoccoro A, Nicolia V, Scarpa S, Kovacs GG, Fiorenza MT, Lucarelli M, Aronica E, Ferrer I, Coppedè F, Troen AM, Fuso A.

Epigenetics. 2020 Feb 5:1-19. doi: 10.1080/15592294.2020.1722917. [Epub ahead of print]

PMID:
32019393
3.

Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates.

Ling H, Gelpi E, Davey K, Jaunmuktane Z, Mok KY, Jabbari E, Simone R, R'Bibo L, Brandner S, Ellis MJ, Attems J, Mann D, Halliday GM, Al-Sarraj S, Hedreen J, Ironside JW, Kovacs GG, Kovari E, Love S, Vonsattel JPG, Allinson KSJ, Hansen D, Bradshaw T, Setó-Salvia N, Wray S, de Silva R, Morris HR, Warner TT, Hardy J, Holton JL, Revesz T.

Acta Neuropathol. 2020 Apr;139(4):717-734. doi: 10.1007/s00401-019-02119-4. Epub 2020 Jan 16.

4.

Proteomics-Enriched Prediction Model for Poor Neurologic Outcome in Cardiac Arrest Survivors.

Distelmaier K, Muqaku B, Wurm R, Arfsten H, Seidel S, Kovacs GG, Mayer RL, Szekeres T, Wallisch C, Hubner P, Goliasch G, Heinze G, Heinz G, Sterz F, Gerner C, Adlbrecht C.

Crit Care Med. 2020 Feb;48(2):167-175. doi: 10.1097/CCM.0000000000004105.

PMID:
31939784
5.

Globular Glial Tauopathy Type I Presenting as Atypical Progressive Aphasia, With Comorbid Limbic-Predominant Age-Related TDP-43 Encephalopathy.

Rusina R, Csefalvay Z, Kovacs GG, Keller J, Javurkova A, Matej R.

Front Aging Neurosci. 2019 Dec 11;11:336. doi: 10.3389/fnagi.2019.00336. eCollection 2019.

6.

Brain-wide genetic mapping identifies the indusium griseum as a prenatal target of pharmacologically unrelated psychostimulants.

Fuzik J, Rehman S, Girach F, Miklosi AG, Korchynska S, Arque G, Romanov RA, Hanics J, Wagner L, Meletis K, Yanagawa Y, Kovacs GG, Alpár A, Hökfelt TGM, Harkany T.

Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25958-25967. doi: 10.1073/pnas.1904006116. Epub 2019 Dec 3.

PMID:
31796600
7.

Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease Patients.

Zerr I, Villar-Piqué A, Schmitz VE, Poleggi A, Pocchiari M, Sánchez-Valle R, Calero M, Calero O, Baldeiras I, Santana I, Kovacs GG, Llorens F, Schmitz M.

Biomolecules. 2019 Nov 28;9(12). pii: E800. doi: 10.3390/biom9120800.

8.

Corticobasal degeneration.

Saranza GM, Whitwell JL, Kovacs GG, Lang AE.

Int Rev Neurobiol. 2019;149:87-136. doi: 10.1016/bs.irn.2019.10.014. Epub 2019 Nov 21.

PMID:
31779825
9.

Alterations in GABAA Receptor Subunit Expression in the Amygdala and Entorhinal Cortex in Human Temporal Lobe Epilepsy.

Stefanits H, Milenkovic I, Mahr N, Pataraia E, Baumgartner C, Hainfellner JA, Kovacs GG, Kasprian G, Sieghart W, Yilmazer-Hanke D, Czech T.

J Neuropathol Exp Neurol. 2019 Nov 1;78(11):1022-1048. doi: 10.1093/jnen/nlz085.

PMID:
31631219
10.

α-Synuclein RT-QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies.

Bongianni M, Ladogana A, Capaldi S, Klotz S, Baiardi S, Cagnin A, Perra D, Fiorini M, Poleggi A, Legname G, Cattaruzza T, Janes F, Tabaton M, Ghetti B, Monaco S, Kovacs GG, Parchi P, Pocchiari M, Zanusso G.

Ann Clin Transl Neurol. 2019 Oct;6(10):2120-2126. doi: 10.1002/acn3.50897. Epub 2019 Oct 10.

11.

Validation of the movement disorder society criteria for the diagnosis of 4-repeat tauopathies.

Respondek G, Grimm MJ, Piot I, Arzberger T, Compta Y, Englund E, Ferguson LW, Gelpi E, Roeber S, Giese A, Grossman M, Irwin DJ, Meissner WG, Nilsson C, Pantelyat A, Rajput A, van Swieten JC, Troakes C, Höglinger GU; Movement Disorder Society-Endorsed Progressive Supranuclear Palsy Study Group.

Mov Disord. 2020 Jan;35(1):171-176. doi: 10.1002/mds.27872. Epub 2019 Sep 30.

PMID:
31571273
12.

Beyond the synucleinopathies: alpha synuclein as a driving force in neurodegenerative comorbidities.

Visanji NP, Lang AE, Kovacs GG.

Transl Neurodegener. 2019 Sep 4;8:28. doi: 10.1186/s40035-019-0172-x. eCollection 2019. Review.

13.

Predominant neurological phenotype in a Hungarian family with two novel mutations in the XPA gene-case series.

Zádori D, Szpisjak L, Németh IB, Reisz Z, Kovacs GG, Szépfalusi N, Németh VL, Maróti Z, Tóth-Molnár E, Oláh J, Vécsei L, Klivényi P, Kalmár T.

Neurol Sci. 2020 Jan;41(1):125-129. doi: 10.1007/s10072-019-04044-6. Epub 2019 Sep 2.

14.

Molecular pathology of neurodegenerative diseases: principles and practice.

Kovacs GG.

J Clin Pathol. 2019 Nov;72(11):725-735. doi: 10.1136/jclinpath-2019-205952. Epub 2019 Aug 8. Review.

PMID:
31395625
15.

Reply: LATE to the PART-y.

Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Fardo DW, Flanagan ME, Halliday G, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey AI, Makkinejad N, Montine TJ, Murray ME, Nag S, Seeley WW, Sperling RA, White CL, Schneider JA.

Brain. 2019 Sep 1;142(9):e48. doi: 10.1093/brain/awz226. No abstract available.

PMID:
31359039
16.

Four-repeat tauopathies.

Rösler TW, Tayaranian Marvian A, Brendel M, Nykänen NP, Höllerhage M, Schwarz SC, Hopfner F, Koeglsperger T, Respondek G, Schweyer K, Levin J, Villemagne VL, Barthel H, Sabri O, Müller U, Meissner WG, Kovacs GG, Höglinger GU.

Prog Neurobiol. 2019 Sep;180:101644. doi: 10.1016/j.pneurobio.2019.101644. Epub 2019 Jun 22. Review.

PMID:
31238088
17.

Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer's disease.

Zahola P, Hanics J, Pintér A, Máté Z, Gáspárdy A, Hevesi Z, Echevarria D, Adori C, Barde S, Törőcsik B, Erdélyi F, Szabó G, Wagner L, Kovacs GG, Hökfelt T, Harkany T, Alpár A.

Brain Struct Funct. 2019 Jul;224(6):2061-2078. doi: 10.1007/s00429-019-01886-w. Epub 2019 May 29.

18.

Experimental Motor Neuron Disease Induced in Mice with Long-Term Repeated Intraperitoneal Injections of Serum from ALS Patients.

Obál I, Nógrádi B, Meszlényi V, Patai R, Ricken G, Kovacs GG, Tripolszki K, Széll M, Siklós L, Engelhardt JI.

Int J Mol Sci. 2019 May 25;20(10). pii: E2573. doi: 10.3390/ijms20102573.

19.

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, Hokkanen SRK, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey AI, Makkinejad N, Montine TJ, Murayama S, Murray ME, Nag S, Rissman RA, Seeley WW, Sperling RA, White Iii CL, Yu L, Schneider JA.

Brain. 2019 Jun 1;142(6):1503-1527. doi: 10.1093/brain/awz099. Erratum in: Brain. 2019 Jul 1;142(7):e37.

20.

Chronic Traumatic Encephalopathy (CTE) Is Absent From a European Community-Based Aging Cohort While Cortical Aging-Related Tau Astrogliopathy (ARTAG) Is Highly Prevalent.

Forrest SL, Kril JJ, Wagner S, Hönigschnabl S, Reiner A, Fischer P, Kovacs GG.

J Neuropathol Exp Neurol. 2019 May 1;78(5):398-405. doi: 10.1093/jnen/nlz017.

PMID:
30939193
21.

Pyramidal system involvement in progressive supranuclear palsy - a clinicopathological correlation.

Stejskalova Z, Rohan Z, Rusina R, Tesar A, Kukal J, Kovacs GG, Bartos A, Matej R.

BMC Neurol. 2019 Mar 20;19(1):42. doi: 10.1186/s12883-019-1270-1.

22.

Accumulation of prion protein in the vagus nerve in creutzfeldt-jakob disease.

Kresl P, Rahimi J, Gelpi E, Aldecoa I, Ricken G, Danics K, Keller E, Kovacs GG.

Ann Neurol. 2019 May;85(5):782-787. doi: 10.1002/ana.25451. Epub 2019 Mar 11.

23.

A walk through tau therapeutic strategies.

Jadhav S, Avila J, Schöll M, Kovacs GG, Kövari E, Skrabana R, Evans LD, Kontsekova E, Malawska B, de Silva R, Buee L, Zilka N.

Acta Neuropathol Commun. 2019 Feb 15;7(1):22. doi: 10.1186/s40478-019-0664-z. Review.

24.

Macrophagic scavenging of Aβ.

Gelpi E, Klotz S, Lang A, Stögmann E, Kovacs GG.

Clin Neuropathol. 2019 Mar/Apr;38(2):48-50. doi: 10.5414/NP301175. No abstract available.

25.

Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.

Alexander J, Ströbel T, Georgitsi M, Hönigschnabl S, Reiner A, Fischer P, Tsifintaris M, Paschou P, Kovacs GG.

Alzheimer Dis Assoc Disord. 2019 Jan-Mar;33(1):7-14. doi: 10.1097/WAD.0000000000000294.

PMID:
30681437
26.

Are comorbidities compatible with a molecular pathological classification of neurodegenerative diseases?

Kovacs GG.

Curr Opin Neurol. 2019 Apr;32(2):279-291. doi: 10.1097/WCO.0000000000000664. Review.

PMID:
30672825
27.

Prediction of Autopsy Verified Neuropathological Change of Alzheimer's Disease Using Machine Learning and MRI.

Kautzky A, Seiger R, Hahn A, Fischer P, Krampla W, Kasper S, Kovacs GG, Lanzenberger R.

Front Aging Neurosci. 2018 Dec 10;10:406. doi: 10.3389/fnagi.2018.00406. eCollection 2018.

28.

Atypical parkinsonism of progressive supranuclear palsy-parkinsonism (PSP-P) phenotype with rare variants in FBXO7 and VPS35 genes associated with Lewy body pathology.

Menšíková K, Tučková L, Kolařiková K, Bartoníková T, Vodička R, Ehrmann J, Vrtěl R, Procházka M, Kaňovský P, Kovacs GG.

Acta Neuropathol. 2019 Jan;137(1):171-173. doi: 10.1007/s00401-018-1923-y. Epub 2018 Oct 29. No abstract available.

PMID:
30374525
29.

Clinical Neuropathology image 6-2018: Metastasis of breast carcinoma to meningioma.

Klotz S, Matula C, Pones M, Herac M, Grisold A, Hainfellner JA, Kovacs GG, Gelpi E.

Clin Neuropathol. 2018 Nov/Dec;37(6):252-253. doi: 10.5414/NP301150. No abstract available.

30.

α-Synuclein antibody 5G4 identifies manifest and prodromal Parkinson's disease in colonic mucosa.

Skorvanek M, Gelpi E, Mechirova E, Ladomirjakova Z, Han V, Lesko N, Feketeova E, Repkova B, Urbancikova Z, Vargova A, Spisak P, Ribeiro Ventosa J, Kudela F, Kulcsarova K, Babinska S, Toth S, Gombosova L, Zakuciova M, Veseliny E, Trebuna F, Lutz MI, Gdovinova Z, Kovacs GG; PARCAS studygroup.

Mov Disord. 2018 Aug;33(8):1366-1368. doi: 10.1002/mds.27380. No abstract available.

PMID:
30230627
31.

Non-motor Behavioral Alterations of PGC-1α-Deficient Mice - A Peculiar Phenotype With Slight Male Preponderance and No Apparent Progression.

Szalardy L, Molnar MF, Zadori D, Cseh EK, Veres G, Kovacs GG, Vecsei L, Klivenyi P.

Front Behav Neurosci. 2018 Aug 27;12:180. doi: 10.3389/fnbeh.2018.00180. eCollection 2018.

32.

S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer's Disease.

Wang C, Iashchishyn IA, Pansieri J, Nyström S, Klementieva O, Kara J, Horvath I, Moskalenko R, Rofougaran R, Gouras G, Kovacs GG, Shankar SK, Morozova-Roche LA.

Sci Rep. 2018 Aug 27;8(1):12836. doi: 10.1038/s41598-018-31141-x.

33.

[Tauopathies : From molecule to therapy].

Kovacs GG, Respondek G, van Eimeren T, Höller E, Levin J, Müller U, Schwarz S, Rösler TW, Schweyer K, Höglinger GU.

Nervenarzt. 2018 Oct;89(10):1083-1094. doi: 10.1007/s00115-018-0584-3. German.

PMID:
30120488
34.

New classification of tauopathies.

Höglinger GU, Respondek G, Kovacs GG.

Rev Neurol (Paris). 2018 Nov;174(9):664-668. doi: 10.1016/j.neurol.2018.07.001. Epub 2018 Aug 8. Review.

PMID:
30098799
35.

Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms.

Fekete R, Cserép C, Lénárt N, Tóth K, Orsolits B, Martinecz B, Méhes E, Szabó B, Németh V, Gönci B, Sperlágh B, Boldogkői Z, Kittel Á, Baranyi M, Ferenczi S, Kovács K, Szalay G, Rózsa B, Webb C, Kovacs GG, Hortobágyi T, West BL, Környei Z, Dénes Á.

Acta Neuropathol. 2018 Sep;136(3):461-482. doi: 10.1007/s00401-018-1885-0. Epub 2018 Jul 19.

36.

Prion replication environment defines the fate of prion strain adaptation.

Katorcha E, Gonzalez-Montalban N, Makarava N, Kovacs GG, Baskakov IV.

PLoS Pathog. 2018 Jun 21;14(6):e1007093. doi: 10.1371/journal.ppat.1007093. eCollection 2018 Jun.

37.

Non-Alzheimer's contributions to dementia and cognitive resilience in The 90+ Study.

Robinson JL, Corrada MM, Kovacs GG, Dominique M, Caswell C, Xie SX, Lee VM, Kawas CH, Trojanowski JQ.

Acta Neuropathol. 2018 Sep;136(3):377-388. doi: 10.1007/s00401-018-1872-5. Epub 2018 Jun 18.

38.

Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain.

Kovacs GG, Xie SX, Robinson JL, Lee EB, Smith DH, Schuck T, Lee VM, Trojanowski JQ.

Acta Neuropathol Commun. 2018 Jun 11;6(1):50. doi: 10.1186/s40478-018-0552-y.

39.

Genetic Creutzfeldt-Jakob disease.

Ladogana A, Kovacs GG.

Handb Clin Neurol. 2018;153:219-242. doi: 10.1016/B978-0-444-63945-5.00013-1.

PMID:
29887139
40.

Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson's disease: ex vivo and in vitro studies.

Horvath I, Iashchishyn IA, Moskalenko RA, Wang C, Wärmländer SKTS, Wallin C, Gräslund A, Kovacs GG, Morozova-Roche LA.

J Neuroinflammation. 2018 Jun 4;15(1):172. doi: 10.1186/s12974-018-1210-9.

41.

α-Synuclein aggregates in labial salivary glands of idiopathic rapid eye movement sleep behavior disorder.

Iranzo A, Borrego S, Vilaseca I, Martí C, Serradell M, Sánchez-Valle R, Kovacs GG, Valldeoriola F, Gaig C, Santamaria J, Tolosa E, Gelpi E.

Sleep. 2018 Aug 1;41(8). doi: 10.1093/sleep/zsy101.

PMID:
29790977
42.

Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer's Disease Adults.

Cipriani S, Ferrer I, Aronica E, Kovacs GG, Verney C, Nardelli J, Khung S, Delezoide AL, Milenkovic I, Rasika S, Manivet P, Benifla JL, Deriot N, Gressens P, Adle-Biassette H.

Cereb Cortex. 2018 Jul 1;28(7):2458-2478. doi: 10.1093/cercor/bhy096.

43.

Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7.

Sukseree S, László L, Gruber F, Bergmann S, Narzt MS, Nagelreiter IM, Höftberger R, Molnár K, Rauter G, Birngruber T, Larue L, Kovacs GG, Tschachler E, Eckhart L.

Mol Neurobiol. 2018 Nov;55(11):8425-8437. doi: 10.1007/s12035-018-0996-x. Epub 2018 Mar 17.

44.

Lysosomal response in relation to α-synuclein pathology differs between Parkinson's disease and multiple system atrophy.

Puska G, Lutz MI, Molnar K, Regelsberger G, Ricken G, Pirker W, Laszlo L, Kovacs GG.

Neurobiol Dis. 2018 Jun;114:140-152. doi: 10.1016/j.nbd.2018.02.019. Epub 2018 Mar 2.

PMID:
29505813
45.

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases.

Vanni S, Zattoni M, Moda F, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Carmona M, Ferrer I, Kovacs GG, Legname G.

Front Neurosci. 2018 Jan 22;12:8. doi: 10.3389/fnins.2018.00008. eCollection 2018.

46.

GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome.

Milenkovic I, Stojanovic T, Aronica E, Fülöp L, Bozsó Z, Máté Z, Yanagawa Y, Adle-Biassette H, Lubec G, Szabó G, Harkany T, Kovács GG, Keimpema E.

Brain Struct Funct. 2018 Apr;223(3):1501-1518. doi: 10.1007/s00429-017-1563-3. Epub 2017 Nov 22.

47.

Differential overexpression of SERPINA3 in human prion diseases.

Vanni S, Moda F, Zattoni M, Bistaffa E, De Cecco E, Rossi M, Giaccone G, Tagliavini F, Haïk S, Deslys JP, Zanusso G, Ironside JW, Ferrer I, Kovacs GG, Legname G.

Sci Rep. 2017 Nov 15;7(1):15637. doi: 10.1038/s41598-017-15778-8.

48.

Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study.

Skrobot OA, Black SE, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, O'Brien J, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I; VICCCS group, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG.

Alzheimers Dement. 2018 Mar;14(3):280-292. doi: 10.1016/j.jalz.2017.09.007. Epub 2017 Oct 19.

PMID:
29055812
49.

GABAA receptor subunits in the human amygdala and hippocampus: Immunohistochemical distribution of 7 subunits.

Stefanits H, Milenkovic I, Mahr N, Pataraia E, Hainfellner JA, Kovacs GG, Sieghart W, Yilmazer-Hanke D, Czech T.

J Comp Neurol. 2018 Feb 1;526(2):324-348. doi: 10.1002/cne.24337. Epub 2017 Oct 29.

PMID:
29023704
50.

Preface.

Kovacs GG, Alafuzoff I.

Handb Clin Neurol. 2017;145:ix. doi: 10.1016/B978-0-12-802395-2.09986-7. No abstract available.

PMID:
28987199

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