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Items: 42

1.

Getting personal with the "reproducibility crisis": interviews in the animal research community.

Fitzpatrick BG, Koustova E, Wang Y.

Lab Anim (NY). 2018 Jul;47(7):175-177. doi: 10.1038/s41684-018-0088-6. No abstract available.

PMID:
29942056
2.

Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets.

Bespalov A, Steckler T, Altevogt B, Koustova E, Skolnick P, Deaver D, Millan MJ, Bastlund JF, Doller D, Witkin J, Moser P, O'Donnell P, Ebert U, Geyer MA, Prinssen E, Ballard T, Macleod M.

Nat Rev Drug Discov. 2016 Jul;15(7):516. doi: 10.1038/nrd.2016.88. Epub 2016 Jun 17. No abstract available.

PMID:
27312728
3.

The preclinical data forum network: A new ECNP initiative to improve data quality and robustness for (preclinical) neuroscience.

Steckler T, Brose K, Haas M, Kas MJ, Koustova E, Bespalov A; ECNP Preclinical Data Forum Network.

Eur Neuropsychopharmacol. 2015 Oct;25(10):1803-7. doi: 10.1016/j.euroneuro.2015.05.011. Epub 2015 Jun 4.

PMID:
26073278
4.

Treatments for nicotine addiction should be a top priority.

Pollock JD, Koustova E, Hoffman A, Shurtleff D, Volkow ND.

Lancet. 2009 Aug 15;374(9689):513-4. doi: 10.1016/S0140-6736(09)60352-4. Epub 2009 Apr 24. No abstract available.

5.

Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock.

Gonzales ER, Chen H, Munuve RM, Mehrani T, Nadel A, Koustova E.

J Trauma. 2008 Sep;65(3):554-65. doi: 10.1097/TA.0b013e31818233ef.

PMID:
18784568
6.

Impact of resuscitation strategies on the acetylation status of cardiac histones in a swine model of hemorrhage.

Alam HB, Shults C, Ahuja N, Ayuste EC, Chen H, Koustova E, Sailhamer EA, Li Y, Liu B, de Moya M, Velmahos GC.

Resuscitation. 2008 Feb;76(2):299-310. Epub 2007 Sep 5.

PMID:
17822827
7.

Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: effect of different resuscitation strategies on lung and liver.

Lin T, Chen H, Koustova E, Sailhamer EA, Li Y, Shults C, Liu B, Rhee P, Kirkpatrick J, Alam HB.

Surgery. 2007 Jun;141(6):784-94.

PMID:
17560255
8.

Differential effect of resuscitation on Toll-like receptors in a model of hemorrhagic shock without a septic challenge.

Chen H, Koustova E, Shults C, Sailhamer EA, Alam HB.

Resuscitation. 2007 Sep;74(3):526-37. Epub 2007 Mar 26.

PMID:
17386967
9.

Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain.

Basile AS, Janowsky A, Golembiowska K, Kowalska M, Tam E, Benveniste M, Popik P, Nikiforuk A, Krawczyk M, Nowak G, Krieter PA, Lippa AS, Skolnick P, Koustova E.

J Pharmacol Exp Ther. 2007 Jun;321(3):1208-25. Epub 2007 Feb 26.

PMID:
17325229
10.

To heal and to serve: military medical education throughout the centuries.

Scultetus AH, Villavicencio JL, Koustova E, Rich NM.

J Am Coll Surg. 2006 Jun;202(6):1005-16. No abstract available.

PMID:
16735218
11.

Valproic acid prevents hemorrhage-associated lethality and affects the acetylation pattern of cardiac histones.

Gonzales E, Chen H, Munuve R, Mehrani T, Britten-Webb J, Nadel A, Alam HB, Wherry D, Burris D, Koustova E.

Shock. 2006 Apr;25(4):395-401.

PMID:
16670643
12.

Identification of expression patterns associated with hemorrhage and resuscitation: integrated approach to data analysis.

Chen H, Alam HB, Querol RI, Rhee P, Li Y, Koustova E.

J Trauma. 2006 Apr;60(4):701-23; discussion 723-4.

PMID:
16612289
13.

Cardiac histones are substrates of histone deacetylase activity in hemorrhagic shock and resuscitation.

Lin T, Alam HB, Chen H, Britten-Webb J, Rhee P, Kirkpatrick J, Koustova E.

Surgery. 2006 Mar;139(3):365-76.

PMID:
16546502
14.

Hepatic and pulmonary apoptosis after hemorrhagic shock in swine can be reduced through modifications of conventional Ringer's solution.

Ayuste EC, Chen H, Koustova E, Rhee P, Ahuja N, Chen Z, Valeri CR, Spaniolas K, Mehrani T, Alam HB.

J Trauma. 2006 Jan;60(1):52-63.

PMID:
16456436
15.

Energy substrate-supplemented resuscitation affects brain monocarboxylate transporter levels and gliosis in a rat model of hemorrhagic shock.

Lin T, Koustova E, Chen H, Rhee PM, Kirkpatrick J, Alam HB.

J Trauma. 2005 Nov;59(5):1191-202; discussion 1202.

PMID:
16385299
16.

Hepatic apoptosis after hemorrhagic shock in rats can be reduced through modifications of conventional Ringer's solution.

Jaskille A, Koustova E, Rhee P, Britten-Webb J, Chen H, Valeri CR, Kirkpatrick JR, Alam HB.

J Am Coll Surg. 2006 Jan;202(1):25-35. Epub 2005 Nov 10.

PMID:
16377494
17.

Induction of profound hypothermia modulates the immune/inflammatory response in a swine model of lethal hemorrhage.

Chen Z, Chen H, Rhee P, Koustova E, Ayuste EC, Honma K, Nadel A, Alam HB.

Resuscitation. 2005 Aug;66(2):209-16. Epub 2005 Apr 19.

PMID:
16053944
18.

Profound hypothermia protects neurons and astrocytes, and preserves cognitive functions in a Swine model of lethal hemorrhage.

Alam HB, Chen Z, Ahuja N, Chen H, Conran R, Ayuste EC, Toruno K, Ariaban N, Rhee P, Nadel A, Koustova E.

J Surg Res. 2005 Jun 15;126(2):172-81.

PMID:
15919416
19.

Combat casualty care research: from bench to the battlefield.

Alam HB, Koustova E, Rhee P.

World J Surg. 2005;29 Suppl 1:S7-11. Review.

PMID:
15815839
20.

Differential expression of extracellular matrix remodeling genes in rat model of hemorrhagic shock and resuscitation.

Chen H, Inocencio R, Alam HB, Rhee P, Koustova E.

J Surg Res. 2005 Feb;123(2):235-44.

PMID:
15680384
21.

The rate of induction of hypothermic arrest determines the outcome in a Swine model of lethal hemorrhage.

Alam HB, Chen Z, Honma K, Koustova E, Querol RI, Jaskille A, Inocencio R, Ariaban N, Toruno K, Nadel A, Rhee P.

J Trauma. 2004 Nov;57(5):961-9.

PMID:
15580018
22.

M2 muscarinic acetylcholine receptor knock-out mice show deficits in behavioral flexibility, working memory, and hippocampal plasticity.

Seeger T, Fedorova I, Zheng F, Miyakawa T, Koustova E, Gomeza J, Basile AS, Alzheimer C, Wess J.

J Neurosci. 2004 Nov 10;24(45):10117-27.

23.

D-lactate increases pulmonary apoptosis by restricting phosphorylation of bad and eNOS in a rat model of hemorrhagic shock.

Jaskille A, Alam HB, Rhee P, Hanes W, Kirkpatrick JR, Koustova E.

J Trauma. 2004 Aug;57(2):262-69; discussion 269-70.

PMID:
15345971
24.

Application of a zeolite hemostatic agent achieves 100% survival in a lethal model of complex groin injury in Swine.

Alam HB, Chen Z, Jaskille A, Querol RI, Koustova E, Inocencio R, Conran R, Seufert A, Ariaban N, Toruno K, Rhee P.

J Trauma. 2004 May;56(5):974-83.

PMID:
15179235
25.

Effect of different resuscitation strategies on neutrophil activation in a swine model of hemorrhagic shock.

Alam HB, Stanton K, Koustova E, Burris D, Rich N, Rhee P.

Resuscitation. 2004 Jan;60(1):91-9.

PMID:
14987788
26.

Clinical and molecular biologic characteristics of early-onset versus late-onset colorectal carcinoma in Filipinos.

Uy GB, Kaw LL, Punzalan CK, Querol RI, Koustova EV, Bowyer MW, Hobbs CM, Sobin LH, Wherry DC.

World J Surg. 2004 Feb;28(2):117-23. Epub 2004 Jan 8.

PMID:
14708047
27.

A portable handpump is effective in the evacuation of hemothorax in a swine model of penetrating chest injury.

Jaskille A, Rhee P, Koustova E, Hancock T, Inocencio R, Lewis TA, Seufert A, Alam HB.

J Trauma. 2003 Nov;55(5):864-8.

PMID:
14608158
28.

Ketone and pyruvate Ringer's solutions decrease pulmonary apoptosis in a rat model of severe hemorrhagic shock and resuscitation.

Koustova E, Rhee P, Hancock T, Chen H, Inocencio R, Jaskille A, Hanes W, Valeri CR, Alam HB.

Surgery. 2003 Aug;134(2):267-74.

PMID:
12947328
29.

cDNA profiling in leukocytes exposed to hypertonic resuscitation fluids.

Gushchin V, Alam HB, Rhee P, Kirkpatrick JR, Koustova E.

J Am Coll Surg. 2003 Sep;197(3):426-32.

PMID:
12946798
30.

Comparative analysis of hemostatic agents in a swine model of lethal groin injury.

Alam HB, Uy GB, Miller D, Koustova E, Hancock T, Inocencio R, Anderson D, Llorente O, Rhee P.

J Trauma. 2003 Jun;54(6):1077-82.

PMID:
12813325
31.

Human polymorphonuclear cell death after exposure to resuscitation fluids in vitro: apoptosis versus necrosis.

Stanton K, Alam HB, Rhee P, Llorente O, Kirkpatrick J, Koustova E.

J Trauma. 2003 Jun;54(6):1065-74; discussion 1075-6.

PMID:
12813324
32.
33.

Learning and memory is preserved after induced asanguineous hyperkalemic hypothermic arrest in a swine model of traumatic exsanguination.

Alam HB, Bowyer MW, Koustova E, Gushchin V, Anderson D, Stanton K, Kreishman P, Cryer CM, Hancock T, Rhee P.

Surgery. 2002 Aug;132(2):278-88.

PMID:
12219024
34.

cDNA array analysis of gene expression following hemorrhagic shock and resuscitation in rats.

Alam HB, Stegalkina S, Rhee P, Koustova E.

Resuscitation. 2002 Aug;54(2):195-206.

PMID:
12161300
35.

Effects of lactated Ringer's solutions on human leukocytes.

Koustova E, Stanton K, Gushchin V, Alam HB, Stegalkina S, Rhee PM.

J Trauma. 2002 May;52(5):872-8.

PMID:
11988652
36.

Cytokine expression profiling in human leukocytes after exposure to hypertonic and isotonic fluids.

Gushchin V, Stegalkina S, Alam HB, Kirkpatrick JR, Rhee PM, Koustova E.

J Trauma. 2002 May;52(5):867-71.

PMID:
11988651
37.

Hypertonic saline: intraosseous infusion causes myonecrosis in a dehydrated swine model of uncontrolled hemorrhagic shock.

Alam HB, Punzalan CM, Koustova E, Bowyer MW, Rhee P.

J Trauma. 2002 Jan;52(1):18-25.

PMID:
11791047
38.

IgG isolated from LP-BM5 infected mouse brain activates ionotropic glutamate receptors.

Basile AS, Koustova E, Ioan P, Rizzoli S, Rogawski MA, Usherwood PN.

Neurobiol Dis. 2001 Dec;8(6):1069-81.

PMID:
11741402
39.
40.

LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor.

Koustova E, Sei Y, Fossom L, Wei ML, Usherwood PN, Keele NB, Rogawski MA, Basile AS.

J Clin Invest. 2001 Mar;107(6):737-44.

41.

Accelerated development of neurochemical and behavioral deficits in LP-BM5 infected mice with targeted deletions of the IFN-gamma gene.

Koustova E, Sei Y, McCarty T, Espey MG, Ming R, Morse HC 3rd, Basile AS.

J Neuroimmunol. 2000 Aug 1;108(1-2):112-21.

PMID:
10900344
42.

Induced hypothermia during emergency department thoracotomy: an animal model.

Rhee P, Talon E, Eifert S, Anderson D, Stanton K, Koustova E, Ling G, Burris D, Kaufmann C, Mongan P, Rich NM, Taylor M, Sun L.

J Trauma. 2000 Mar;48(3):439-47; discussion 447-50.

PMID:
10744281

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