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Items: 22


In vitro and in vivo efficacy of an anti-CD203c conjugated antibody (AGS-16C3F) in mouse models of advanced systemic mastocytosis.

Zhang Y, Wedeh G, He L, Wittner M, Beghi F, Baral V, Launay JM, Bibi S, Doñate F, Kouros-Mehr H, Arock M, Louache F.

Blood Adv. 2019 Feb 26;3(4):633-643. doi: 10.1182/bloodadvances.2018026179.


MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene.

Phua YW, Nguyen A, Roden DL, Elsworth B, Deng N, Nikolic I, Yang J, Mcfarland A, Russell R, Kaplan W, Cowley MJ, Nair R, Zotenko E, O'Toole S, Tan SX, James DE, Clark SJ, Kouros-Mehr H, Swarbrick A.

Breast Cancer Res. 2015 Jun 13;17:83. doi: 10.1186/s13058-015-0593-0.


Identification of druggable cancer driver genes amplified across TCGA datasets.

Chen Y, McGee J, Chen X, Doman TN, Gong X, Zhang Y, Hamm N, Ma X, Higgs RE, Bhagwat SV, Buchanan S, Peng SB, Staschke KA, Yadav V, Yue Y, Kouros-Mehr H.

PLoS One. 2014 May 29;9(5):e98293. doi: 10.1371/journal.pone.0098293. eCollection 2014. Erratum in: PLoS One. 2014;9(9):e107646.


Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß.

Chu IM, Lai WC, Aprelikova O, El Touny LH, Kouros-Mehr H, Green JE.

PLoS One. 2013;8(4):e61125. doi: 10.1371/journal.pone.0061125. Epub 2013 Apr 8.


Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model.

Franci C, Zhou J, Jiang Z, Modrusan Z, Good Z, Jackson E, Kouros-Mehr H.

PLoS One. 2013;8(3):e58183. doi: 10.1371/journal.pone.0058183. Epub 2013 Mar 8.


The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression.

Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, Sweeney CA, Collins CC, Gray JW, Chang HY, Werb Z.

Cancer Discov. 2012 Jul;2(7):638-51. doi: 10.1158/2159-8290.CD-12-0093. Epub 2012 May 10.


Use of anti-VEGF adjuvant therapy in cancer: challenges and rationale.

Bagri A, Kouros-Mehr H, Leong KG, Plowman GD.

Trends Mol Med. 2010 Mar;16(3):122-32. doi: 10.1016/j.molmed.2010.01.004. Epub 2010 Feb 26. Review.


GATA-3 and the regulation of the mammary luminal cell fate.

Kouros-Mehr H, Kim JW, Bechis SK, Werb Z.

Curr Opin Cell Biol. 2008 Apr;20(2):164-70. doi: 10.1016/ Epub 2008 Mar 21. Review.


GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.

Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z.

Cancer Cell. 2008 Feb;13(2):141-52. doi: 10.1016/j.ccr.2008.01.011.


Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells.

Reinhold WC, Reimers MA, Maunakea AK, Kim S, Lababidi S, Scherf U, Shankavaram UT, Ziegler MS, Stewart C, Kouros-Mehr H, Cui H, Dolginow D, Scudiero DA, Pommier YG, Munroe DJ, Feinberg AP, Weinstein JN.

Mol Cancer Ther. 2007 Feb;6(2):391-403. Epub 2007 Feb 1.


GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland.

Kouros-Mehr H, Slorach EM, Sternlicht MD, Werb Z.

Cell. 2006 Dec 1;127(5):1041-55.


Hormonal and local control of mammary branching morphogenesis.

Sternlicht MD, Kouros-Mehr H, Lu P, Werb Z.

Differentiation. 2006 Sep;74(7):365-81. Review.


Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.

Bussey KJ, Chin K, Lababidi S, Reimers M, Reinhold WC, Kuo WL, Gwadry F, Ajay, Kouros-Mehr H, Fridlyand J, Jain A, Collins C, Nishizuka S, Tonon G, Roschke A, Gehlhaus K, Kirsch I, Scudiero DA, Gray JW, Weinstein JN.

Mol Cancer Ther. 2006 Apr;5(4):853-67.


AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies.

Major SM, Nishizuka S, Morita D, Rowland R, Sunshine M, Shankavaram U, Washburn F, Asin D, Kouros-Mehr H, Kane D, Weinstein JN.

BMC Bioinformatics. 2006 Apr 6;7:192.


Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin.

Sternlicht MD, Sunnarborg SW, Kouros-Mehr H, Yu Y, Lee DC, Werb Z.

Development. 2005 Sep;132(17):3923-33. Epub 2005 Aug 3. Erratum in: Development. 2006 Mar;133(6):1203.


Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays.

Nishizuka S, Charboneau L, Young L, Major S, Reinhold WC, Waltham M, Kouros-Mehr H, Bussey KJ, Lee JK, Espina V, Munson PJ, Petricoin E 3rd, Liotta LA, Weinstein JN.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14229-34. Epub 2003 Nov 17.


Apoptotic susceptibility of cancer cells selected for camptothecin resistance: gene expression profiling, functional analysis, and molecular interaction mapping.

Reinhold WC, Kouros-Mehr H, Kohn KW, Maunakea AK, Lababidi S, Roschke A, Stover K, Alexander J, Pantazis P, Miller L, Liu E, Kirsch IR, Urasaki Y, Pommier Y, Weinstein JN.

Cancer Res. 2003 Mar 1;63(5):1000-11.


The bioinformatics of microarray gene expression profiling.

Weinstein JN, Scherf U, Lee JK, Nishizuka S, Gwadry F, Bussey AK, Kim S, Smith LH, Tanabe L, Richman S, Alexander J, Kouros-Mehr H, Maunakea A, Reinhold WC.

Cytometry. 2002 Jan 1;47(1):46-9. Review. No abstract available.


Identification of non-functional human VNO receptor genes provides evidence for vestigiality of the human VNO.

Kouros-Mehr H, Pintchovski S, Melnyk J, Chen YJ, Friedman C, Trask B, Shizuya H.

Chem Senses. 2001 Nov;26(9):1167-74.


The development and applications of the bacterial artificial chromosome cloning system.

Shizuya H, Kouros-Mehr H.

Keio J Med. 2001 Mar;50(1):26-30. Review.


Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes.

Hurowitz EH, Melnyk JM, Chen YJ, Kouros-Mehr H, Simon MI, Shizuya H.

DNA Res. 2000 Apr 28;7(2):111-20.


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