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The natural defense system and the normative self model.

Kourilsky P.

F1000Res. 2016 May 3;5:797. doi: 10.12688/f1000research.8518.1. eCollection 2016.


Does a quorum sensing mechanism direct the behavior of immune cells?

Perié L, Aru J, Kourilsky P, Slotine JJ.

C R Biol. 2013 Jan;336(1):13-6. doi: 10.1016/j.crvi.2013.01.006. Epub 2013 Mar 1. Review.


Systematic and systemic immunology: on the future of research and its applications.

Kourilsky P.

Immunol Res. 2012 Sep;53(1-3):2-10. doi: 10.1007/s12026-012-8316-4.


Preface: Human immunology at SIgN.

Kourilsky P, Ricciardi-Castagnoli P.

Immunol Res. 2012 Sep;53(1-3):1. doi: 10.1007/s12026-012-8326-2. No abstract available.


Selfish cellular networks and the evolution of complex organisms.

Kourilsky P.

C R Biol. 2012 Mar;335(3):169-79. doi: 10.1016/j.crvi.2012.01.003. Epub 2012 Feb 16. Review.


Systems medicine and integrated care to combat chronic noncommunicable diseases.

Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C.

Genome Med. 2011 Jul 6;3(7):43. doi: 10.1186/gm259.


Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets.

Wong KL, Tai JJ, Wong WC, Han H, Sem X, Yeap WH, Kourilsky P, Wong SC.

Blood. 2011 Aug 4;118(5):e16-31. doi: 10.1182/blood-2010-12-326355. Epub 2011 Jun 7.


The CD14(+/low)CD16(+) monocyte subset is more susceptible to spontaneous and oxidant-induced apoptosis than the CD14(+)CD16(-) subset.

Zhao C, Tan YC, Wong WC, Sem X, Zhang H, Han H, Ong SM, Wong KL, Yeap WH, Sze SK, Kourilsky P, Wong SC.

Cell Death Dis. 2010 Nov 4;1:e95. doi: 10.1038/cddis.2010.69.


Identification of novel functional differences in monocyte subsets using proteomic and transcriptomic methods.

Zhao C, Zhang H, Wong WC, Sem X, Han H, Ong SM, Tan YC, Yeap WH, Gan CS, Ng KQ, Koh MB, Kourilsky P, Sze SK, Wong SC.

J Proteome Res. 2009 Aug;8(8):4028-38. doi: 10.1021/pr900364p.


[An immunological Noah's Ark].

Buzoni-Gatel D, Kourilsky P.

Med Sci (Paris). 2009 Mar;25(3):211. doi: 10.1051/medsci/2009253211. French. No abstract available.


IL-1beta, IL-6, and RANTES as biomarkers of Chikungunya severity.

Ng LF, Chow A, Sun YJ, Kwek DJ, Lim PL, Dimatatac F, Ng LC, Ooi EE, Choo KH, Her Z, Kourilsky P, Leo YS.

PLoS One. 2009;4(1):e4261. doi: 10.1371/journal.pone.0004261. Epub 2009 Jan 21.


Many human peripheral VH5-expressing IgM+ B cells display a unique heavy-chain rearrangement.

Lim A, Lemercier B, Wertz X, Pottier SL, Huetz F, Kourilsky P.

Int Immunol. 2008 Jan;20(1):105-16. Epub 2007 Nov 20.


T cell repertoire diversity is required for relapses in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.

Fazilleau N, Delarasse C, Motta I, Fillatreau S, Gougeon ML, Kourilsky P, Pham-Dinh D, Kanellopoulos JM.

J Immunol. 2007 Apr 15;178(8):4865-75.


Lineage relationships, homeostasis, and recall capacities of central- and effector-memory CD8 T cells in vivo.

Bouneaud C, Garcia Z, Kourilsky P, Pannetier C.

J Exp Med. 2005 Feb 21;201(4):579-90. Epub 2005 Feb 14.


Valpha and Vbeta public repertoires are highly conserved in terminal deoxynucleotidyl transferase-deficient mice.

Fazilleau N, Cabaniols JP, Lemaître F, Motta I, Kourilsky P, Kanellopoulos JM.

J Immunol. 2005 Jan 1;174(1):345-55.


Detection of low-frequency human antigen-specific CD4(+) T cells using MHC class II multimer bead sorting and immunoscope analysis.

Lemaître F, Viguier M, Cho MS, Fourneau JM, Maillère B, Kourilsky P, Van Endert PM, Ferradini L.

Eur J Immunol. 2004 Oct;34(10):2941-9.


Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells.

Viguier M, Lemaître F, Verola O, Cho MS, Gorochov G, Dubertret L, Bachelez H, Kourilsky P, Ferradini L.

J Immunol. 2004 Jul 15;173(2):1444-53.


The intratumoral application of poly-G-oligodeoxynucleotides does not augment the naturally induced antitumoral CD8-T-cell response in P815 mastocytomas.

Mempel M, Ronet C, Lemaitre F, Lim A, Kourilsky P, Gachelin G, Musette P.

Immunol Lett. 2003 Oct 9;89(1):47-57.


Follow-up of the T-cell clonality in Sezary patients treated by extracorporeal photopheresis using a new assay: the immunoscope technique.

Ingen-Housz-Oro S, Bussel A, Flageul B, Dubertret L, Michel L, Gachelin G, Kourilsky P, Bachelez H, Musette P.

Transfus Apher Sci. 2003 Feb;28(1):35-42.


The repertoires of circulating human CD8(+) central and effector memory T cell subsets are largely distinct.

Baron V, Bouneaud C, Cumano A, Lim A, Arstila TP, Kourilsky P, Ferradini L, Pannetier C.

Immunity. 2003 Feb;18(2):193-204.


Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice.

Guy-Grand D, Azogui O, Celli S, Darche S, Nussenzweig MC, Kourilsky P, Vassalli P.

J Exp Med. 2003 Feb 3;197(3):333-41.


Mutational analysis and molecular modeling of the binding of Staphylococcus aureus enterotoxin C2 to a murine T cell receptor Vbeta10 chain.

Rössle SC, Bisch PM, Lone YC, Abastado JP, Kourilsky P, Bellio M.

Eur J Immunol. 2002 Aug;32(8):2172-8.


A prospective study on the evolution of the T-cell repertoire in patients with Sézary syndrome treated by extracorporeal photopheresis.

Ingen-Housz-Oro S, Bussel A, Flageul B, Michel L, Dubertret L, Kourilsky P, Gachelin G, Bachelez H, Musette P.

Blood. 2002 Sep 15;100(6):2168-74.


T-cell receptor repertoire and cytokine pattern in granuloma annulare: defining a particular type of cutaneous granulomatous inflammation.

Mempel M, Musette P, Flageul B, Schnopp C, Remling R, Gachelin G, Kourilsky P, Ring J, Abeck D.

J Invest Dermatol. 2002 Jun;118(6):957-66.


[Methods of studying T-lymphocyte repertoires].

Casrouge A, Fazilleau N, Cabaniols JP, Kourilsky P, Kanellopoulos JM.

Pathol Biol (Paris). 2002 Apr;50(3):151-6. French. No abstract available.


Self peptides and the peptidic self.

Kourilsky P, Fazilleau N.

Int Rev Immunol. 2001 Oct;20(5):575-91. Review.


Combination of MHC-peptide multimer-based T cell sorting with the Immunoscope permits sensitive ex vivo quantitation and follow-up of human CD8+ T cell immune responses.

Lim A, Baron V, Ferradini L, Bonneville M, Kourilsky P, Pannetier C.

J Immunol Methods. 2002 Mar 1;261(1-2):177-94.


MHC and MHC-related proteins as pleiotropic signal molecules.

Ojcius DM, Delarbre C, Kourilsky P, Gachelin G.

FASEB J. 2002 Feb;16(2):202-6.


Natural killer T cells restricted by the monomorphic MHC class 1b CD1d1 molecules behave like inflammatory cells.

Mempel M, Ronet C, Suarez F, Gilleron M, Puzo G, Van Kaer L, Lehuen A, Kourilsky P, Gachelin G.

J Immunol. 2002 Jan 1;168(1):365-71.


Most alpha/beta T cell receptor diversity is due to terminal deoxynucleotidyl transferase.

Cabaniols JP, Fazilleau N, Casrouge A, Kourilsky P, Kanellopoulos JM.

J Exp Med. 2001 Nov 5;194(9):1385-90.


Contribution of double-negative thymic precursors to CD8alpha alpha (+) intraepithelial lymphocytes of the gut in mice bearing TCR transgenes.

Guy-Grand D, Pardigon N, Darche S, Lantz O, Kourilsky P, Vassalli P.

Eur J Immunol. 2001 Sep;31(9):2593-602.


Cytokine fields and the polarization of the immune response.

Kourilsky P, Truffa-Bachi P.

Trends Immunol. 2001 Sep;22(9):502-9. Review.


Cross-presentation by dendritic cells of tumor antigen expressed in apoptotic recombinant canarypox virus-infected dendritic cells.

Motta I, André F, Lim A, Tartaglia J, Cox WI, Zitvogel L, Angevin E, Kourilsky P.

J Immunol. 2001 Aug 1;167(3):1795-802.


Unification for European immunology?

Kourilsky P.

Science. 2001 Jul 13;293(5528):173. No abstract available.


Identical T cell clones are located within the mouse gut epithelium and lamina propia and circulate in the thoracic duct lymph.

Arstila T, Arstila TP, Calbo S, Selz F, Malassis-Seris M, Vassalli P, Kourilsky P, Guy-Grand D.

J Exp Med. 2000 Mar 6;191(5):823-34.


Immunoscope analysis of T-lymphocytes infiltrating melanocytic tumors.

Musette P, Even J, Dubertret L, Kourilsky P, Gachelin G.

Methods Mol Med. 2001;61:321-37. doi: 10.1385/1-59259-145-0:321.


Diversity of T cell repertoire shaped by a single peptide ligand is critically affected by its amino acid residue at a T cell receptor contact.

Fukui Y, Oono T, Cabaniols JP, Nakao K, Hirokawa K, Inayoshi A, Sanui T, Kanellopoulos J, Iwata E, Noda M, Katsuki M, Kourilsky P, Sasazuki T.

Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13760-5.


V beta T cell repertoire of CD8+ splenocytes selected on nonpolymorphic MHC class I molecules.

Laouini D, Casrouge A, Dalle S, Lemonnier F, Kourilsky P, Kanellopoulos J.

J Immunol. 2000 Dec 1;165(11):6381-6.


Recombinant viruses as a tool for therapeutic vaccination against human cancers.

Bonnet MC, Tartaglia J, Verdier F, Kourilsky P, Lindberg A, Klein M, Moingeon P.

Immunol Lett. 2000 Sep 15;74(1):11-25. Review.


Facing two T cell epitopes: a degree of randomness in the primary response is lost upon secondary immunization.

Bousso P, Lemaitre F, Bilsborough J, Kourilsky P.

J Immunol. 2000 Jul 15;165(2):760-7.


Diversity of human alpha beta T cell receptors.

Arstila TP, Casrouge A, Baron V, Even J, Kanellopoulos J, Kourilsky P.

Science. 2000 May 19;288(5469):1135. No abstract available.


Size estimate of the alpha beta TCR repertoire of naive mouse splenocytes.

Casrouge A, Beaudoing E, Dalle S, Pannetier C, Kanellopoulos J, Kourilsky P.

J Immunol. 2000 Jun 1;164(11):5782-7.


Delayed and separate costimulation in vitro supports the evidence of a transient "excited" state of CD8+ T cells during activation.

Pardigon N, Cambouris C, Bercovici N, Lemaître F, Liblau R, Kourilsky P.

J Immunol. 2000 May 1;164(9):4493-9.


Role of Qa-1(b)-binding receptors in the specificity of developing NK cells.

Salcedo M, Colucci F, Dyson PJ, Cotterill LA, Lemonnier FA, Kourilsky P, Di Santo JP, Ljunggren HG, Abastado JP.

Eur J Immunol. 2000 Apr;30(4):1094-101.

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