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Advances in molecular, genetic and immune signatures of gastric cancer: Are we ready to apply them in our patients' decision making?

Gkolfinopoulos S, Papamichael D, Papadimitriou K, Papanastasopoulos P, Vassiliou V, Kountourakis P.

World J Gastrointest Oncol. 2018 Jul 15;10(7):172-183. doi: 10.4251/wjgo.v10.i7.172. Review.


Fournier Gangrene in a patient receiving chemo-radiation for rectal cancer.

Pittaka M, Georgiou C, Polyviou P, Kountourakis P, Loizou P, Constantinou I, Andreopoulos D, Vassiliou VP.

Oxf Med Case Reports. 2018 Feb 26;2018(2):omx101. doi: 10.1093/omcr/omx101. eCollection 2018 Feb.


Leptomeningeal metastases originated from esophagogastric junction/gastric cancer: A brief report of two cases.

Kountourakis P, Papamichael D, Haralambous H, Michael M, Nakos G, Lazaridou S, Fotiou E, Vassiliou V, Andreopoulos D.

World J Gastrointest Oncol. 2018 Jan 15;10(1):56-61. doi: 10.4251/wjgo.v10.i1.56.


Chromogranin A as a valid marker in oncology: Clinical application or false hopes?

Gkolfinopoulos S, Tsapakidis K, Papadimitriou K, Papamichael D, Kountourakis P.

World J Methodol. 2017 Mar 26;7(1):9-15. doi: 10.5662/wjm.v7.i1.9. eCollection 2017 Mar 26. Review.


BRCA1 and BRCA2 mutation testing in Cyprus; a population based study.

Loizidou MA, Hadjisavvas A, Pirpa P, Spanou E, Delikurt T, Tanteles GA, Daniel M, Kountourakis P, Malas S, Ioannidis G, Zouvani I, Kakouri E, Papamichael D, Marcou Y, Anastasiadou V, Kyriacou K.

Clin Genet. 2017 Apr;91(4):611-615. doi: 10.1111/cge.12886. Epub 2016 Nov 23.


Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO).

Dervenis C, Xynos E, Sotiropoulos G, Gouvas N, Boukovinas I, Agalianos C, Androulakis N, Athanasiadis A, Christodoulou C, Chrysou E, Emmanouilidis C, Georgiou P, Karachaliou N, Katopodi O, Kountourakis P, Kyriazanos I, Makatsoris T, Papakostas P, Papamichael D, Pechlivanides G, Pentheroudakis G, Pilpilidis I, Sgouros J, Tekkis P, Triantopoulou C, Tzardi M, Vassiliou V, Vini L, Xynogalos S, Ziras N, Souglakos J.

Ann Gastroenterol. 2016 Oct-Dec;29(4):390-416. Epub 2016 Jun 3.


Validity of Adjuvant! Online in older patients with stage III colon cancer based on 2967 patients from the ACCENT database.

Papamichael D, Renfro LA, Matthaiou C, Yothers G, Saltz L, Guthrie KA, Van Cutsem E, Schmoll HJ, Labianca R, André T, O'Connell M, Alberts SR, Haller DG, Kountourakis P, Sargent DJ; Adjuvant Colon Cancer Endpoints (ACCENT) Group.

J Geriatr Oncol. 2016 Nov;7(6):422-429. doi: 10.1016/j.jgo.2016.07.002. Epub 2016 Jul 25.


Follicle-Stimulating Hormone Receptor (FSHR): A Promising Tool in Oncology?

Papadimitriou K, Kountourakis P, Kottorou AE, Antonacopoulou AG, Rolfo C, Peeters M, Kalofonos HP.

Mol Diagn Ther. 2016 Dec;20(6):523-530. Review.


Clinical practice guidelines for the surgical treatment of rectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO).

Xynos E, Tekkis P, Gouvas N, Vini L, Chrysou E, Tzardi M, Vassiliou V, Boukovinas I, Agalianos C, Androulakis N, Athanasiadis A, Christodoulou C, Dervenis C, Emmanouilidis C, Georgiou P, Katopodi O, Kountourakis P, Makatsoris T, Papakostas P, Papamichael D, Pechlivanides G, Pentheroudakis G, Pilpilidis I, Sgouros J, Triantopoulou C, Xynogalos S, Karachaliou N, Ziras N, Zoras O, Souglakos J; [the Executive Team on behalf of the Hellenic Society of Medical Oncologists (HeSMO)].

Ann Gastroenterol. 2016 Apr-Jun;29(2):103-26. doi: 10.20524/aog.2016.0003.


The ALPPS procedure as a novel "liver-first" approach in treating liver metastases of colon cancer: the first experience in Greek Cypriot area.

Petrou A, Moris D, Kountourakis P, Fard-Aghaie M, Neofytou K, Felekouras E, Papalampros A.

World J Surg Oncol. 2016 Mar 8;14:67. doi: 10.1186/s12957-016-0827-3.


Clinical practice guidelines for the surgical management of colon cancer: a consensus statement of the Hellenic and Cypriot Colorectal Cancer Study Group by the HeSMO.

Xynos E, Gouvas N, Triantopoulou C, Tekkis P, Vini L, Tzardi M, Boukovinas I, Androulakis N, Athanasiadis A, Christodoulou C, Chrysou E, Dervenis C, Emmanouilidis C, Georgiou P, Katopodi O, Kountourakis P, Makatsoris T, Papakostas P, Papamichael D, Pentheroudakis G, Pilpilidis I, Sgouros J, Vassiliou V, Xynogalos S, Ziras N, Karachaliou N, Zoras O, Agalianos C, Souglakos J; [the Executive Team on behalf of the Hellenic Society of Medical Oncology (HeSMO)].

Ann Gastroenterol. 2016 Jan-Mar;29(1):3-17.


Adjuvant chemotherapy for colon cancer: a consensus statement of the Hellenic and Cypriot Colorectal Cancer Study Group by the HeSMO.

Kountourakis P, Souglakos J, Gouvas N, Androulakis N, Athanasiadis A, Boukovinas I, Christodoulou C, Chrysou E, Dervenis C, Emmanouilidis C, Georgiou P, Karachaliou N, Katopodi O, Makatsoris T, Papakostas P, Pentheroudakis G, Pilpilidis I, Sgouros J, Tekkis P, Triantopoulou C, Tzardi M, Vassiliou V, Vini L, Xynogalos S, Xynos E, Ziras N, Papamichael D.

Ann Gastroenterol. 2016 Jan-Mar;29(1):18-23.


Adjuvant Chemoradiation Therapy in Gastric Cancer: Critically Reviewing the Past and Visualizing the Next Step Forward.

Papadimitriou K, Antoniou G, Rolfo C, Russo A, Bronte G, Vassiliou V, Papamichael D, Peeters M, Kountourakis P.

Gastroenterol Res Pract. 2015;2015:650846. doi: 10.1155/2015/650846. Epub 2015 May 26. Review.


The mutational spectrum of Lynch syndrome in cyprus.

Loizidou MA, Neophytou I, Papamichael D, Kountourakis P, Vassiliou V, Marcou Y, Kakouri E, Ioannidis G, Philippou C, Spanou E, Tanteles GA, Anastasiadou V, Hadjisavvas A, Kyriacou K.

PLoS One. 2014 Aug 18;9(8):e105501. doi: 10.1371/journal.pone.0105501. eCollection 2014.


Voice disorders induced by bevacizumab administration in an ovarian cancer patient: an underestimated and rare toxicity.

Kountourakis P, Antoniou G, Papadimitriou K, Vassiliou V, Syrigos D, Philippou M, Papamichael D.

Hematol Oncol Stem Cell Ther. 2014 Sep;7(3):123-4. doi: 10.1016/j.hemonc.2014.06.003. Epub 2014 Jul 25. No abstract available.


Treatment of older patients with colorectal cancer: a perspective review.

Kordatou Z, Kountourakis P, Papamichael D.

Ther Adv Med Oncol. 2014 May;6(3):128-40. doi: 10.1177/1758834014523328. Review.


Adjuvant therapy for resectable pancreatic adenocarcinoma: review of the current treatment approaches and future directions.

Antoniou G, Kountourakis P, Papadimitriou K, Vassiliou V, Papamichael D.

Cancer Treat Rev. 2014 Feb;40(1):78-85. doi: 10.1016/j.ctrv.2013.05.008. Epub 2013 Jun 26. Review.


Radiotherapy capacity in Europe.

Charalambous H, Marcou Y, Katodritis N, Kountourakis P, Andreopoulos D.

Lancet Oncol. 2013 May;14(6):e196. doi: 10.1016/S1470-2045(13)70132-3. No abstract available.


Molecular profile of head and neck squamous cell carcinomas bearing p16 high phenotype.

Rampias T, Pectasides E, Prasad M, Sasaki C, Gouveris P, Dimou A, Kountourakis P, Perisanidis C, Burtness B, Zaramboukas T, Rimm D, Fountzilas G, Psyrri A.

Ann Oncol. 2013 Aug;24(8):2124-31. doi: 10.1093/annonc/mdt013. Epub 2013 Feb 13.


Targeting the HER2 receptor in metastatic breast cancer.

Orphanos G, Kountourakis P.

Hematol Oncol Stem Cell Ther. 2012;5(3):127-37. doi: 10.5144/1658-3876.2012.127. Review.


In regard to Samuelian et Al.

Vassiliou V, Kountourakis P.

Int J Radiat Oncol Biol Phys. 2012 Nov 1;84(3):570. doi: 10.1016/j.ijrobp.2012.04.039. No abstract available.


Barrett's Esophagus: A Review of Biology and Therapeutic Approaches.

Kountourakis P, Ajani JA, Davila M, Lee JH, Bhutani MS, Izzo JG.

Gastrointest Cancer Res. 2012 Mar;5(2):49-57.


Bevacizumab therapy may contribute to irradiation deferral in patients with breast cancer and with central nervous system metastases: findings of a case series.

Kountourakis P, Dokou A, Kardara E, Kaltsas S, Doufexis D, Tzovaras A, Mourgela S, Ardavanis A.

Clin Breast Cancer. 2012 Aug;12(4):282-6. doi: 10.1016/j.clbc.2012.04.002. Epub 2012 May 19. No abstract available.


Bilateral de quervain syndrome after aromatase inhibitor administration: a case report and review of the literature.

Papadimitriou K, Kountourakis P, Morakis E, Vassiliou V, Barbounis V, Ardavanis A.

Case Rep Med. 2012;2012:810428. doi: 10.1155/2012/810428. Epub 2012 Apr 11.


Adjuvant chemoradiotherapy (CRT) for high-risk gastric cancer (GC) patients: single-center experience using infusional 5-fluorouracil (5FU) and radiotherapy (RT).

Papadimitriou K, Vassiliou V, Kountourakis P, Polyviou P, Andreopoulos D, Papamichael D.

Med Oncol. 2012 Dec;29(4):2716-7. doi: 10.1007/s12032-012-0206-z. Epub 2012 Mar 15. No abstract available.


Presacral Extramedullary Hematopoiesis in a Patient with Rectal Adenocarcinoma: Report of a Case and Literature Review.

Vassiliou V, Papamichael D, Lutz S, Eracleous E, Kountourakis P, Polyviou P, Michaelides I, Shoukris M, Andreopoulos D.

J Gastrointest Cancer. 2012 Sep;43 Suppl 1:S131-5. doi: 10.1007/s12029-012-9370-9. Review. No abstract available.


Targeted agents: review of toxicity in the elderly metastatic colorectal cancer patients.

Kyriakou F, Kountourakis P, Papamichael D.

Target Oncol. 2011 Dec;6(4):245-51. doi: 10.1007/s11523-011-0198-1. Epub 2011 Nov 9. Review.


Barrett's esophagus: treatment or observation of a major precursor factor of esophageal cancer?

Kountourakis P, Papademetriou K, Ardavanis A, Papamichael D.

J BUON. 2011 Jul-Sep;16(3):425-30. Review.


Comparative prognostic value of epidermal growth factor quantitative protein expression compared with FISH for head and neck squamous cell carcinoma.

Pectasides E, Rampias T, Kountourakis P, Sasaki C, Kowalski D, Fountzilas G, Zaramboukas T, Rimm D, Burtness B, Psyrri A.

Clin Cancer Res. 2011 May 1;17(9):2947-54. doi: 10.1158/1078-0432.CCR-10-2040. Epub 2011 Feb 25.


Visual and hearing loss due to colorectal meningeal carcinomatosis: a case-based review.

Kountourakis P, Ardavanis A.

Clin Adv Hematol Oncol. 2010 Aug;8(8):567-8. Review. No abstract available.


Combined modality therapy of cT2N0M0 esophageal cancer: the University of Texas M. D. Anderson Cancer Center experience.

Kountourakis P, Correa AM, Hofstetter WL, Lee JH, Bhutani MS, Rice DC, Komaki R, Maru DM, Ross WA, Vaporciyan A, Swisher SG, Ajani JA.

Cancer. 2011 Mar 1;117(5):925-30. doi: 10.1002/cncr.25651. Epub 2010 Oct 19.


Neoadjuvant therapy for locally advanced breast cancer: Focus on chemotherapy and biological targeted treatments' armamentarium.

Papadimitriou K, Ardavanis A, Kountourakis P.

J Thorac Dis. 2010 Sep;2(3):160-70. doi: 10.3978/j.issn.2072-1439.2010.02.03.8. Erratum in: J Thorac Dis. 2013 Aug;5(4):E181. Papademetriou, Konstantinos [corrected to Papadimitriou, Konstantinos].


A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancer.

Iliopoulou EG, Kountourakis P, Karamouzis MV, Doufexis D, Ardavanis A, Baxevanis CN, Rigatos G, Papamichail M, Perez SA.

Cancer Immunol Immunother. 2010 Dec;59(12):1781-9. doi: 10.1007/s00262-010-0904-3. Epub 2010 Aug 12.


Bevacizumab combined with two-weekly paclitaxel as first-line therapy for metastatic breast cancer.

Kountourakis P, Doufexis D, Maliou S, Karagiannis A, Kardara E, Margari C, Sykoutri D, Tzovaras A, Ardavanis A.

Anticancer Res. 2010 Jul;30(7):2969-71.


Neoadjuvant sequential epirubicin and docetaxel followed by surgery-radiotherapy and post-operative docetaxel or gemcitabine/vinorelbine combination based on primary response: a multimodality approach for locally advanced breast cancer.

Kountourakis P, Missitzis I, Doufexis D, Zobolas V, Pissakas G, Arnogiannaki N, Maliou S, Sotiropoulou A, Ardavanis A.

J Cancer Res Clin Oncol. 2011 Feb;137(2):221-8. doi: 10.1007/s00432-010-0878-8. Epub 2010 Apr 13.


Nuclear localization of signal transducer and activator of transcription 3 in head and neck squamous cell carcinoma is associated with a better prognosis.

Pectasides E, Egloff AM, Sasaki C, Kountourakis P, Burtness B, Fountzilas G, Dafni U, Zaramboukas T, Rampias T, Rimm D, Grandis J, Psyrri A.

Clin Cancer Res. 2010 Apr 15;16(8):2427-34. doi: 10.1158/1078-0432.CCR-09-2658. Epub 2010 Apr 6.


Activation of Wnt signaling pathway by human papillomavirus E6 and E7 oncogenes in HPV16-positive oropharyngeal squamous carcinoma cells.

Rampias T, Boutati E, Pectasides E, Sasaki C, Kountourakis P, Weinberger P, Psyrri A.

Mol Cancer Res. 2010 Mar;8(3):433-43. doi: 10.1158/1541-7786.MCR-09-0345. Epub 2010 Mar 9.


Synchronous presentation of GISTs and other primary neoplasms: a single center experience.

Arnogiannaki N, Martzoukou I, Kountourakis P, Dimitriadis E, Papathanasaki A, Nastoulis E, Gazalidou M, Fida A, Apostolikas N, Agnantis NJ.

In Vivo. 2010 Jan-Feb;24(1):109-15.


Biweekly gemcitabine (GEM) in combination with erlotinib (ERL): an active and convenient regimen for advanced pancreatic cancer.

Ardavanis A, Kountourakis P, Karagiannis A, Doufexis D, Tzovaras AA, Rigatos G.

Anticancer Res. 2009 Dec;29(12):5211-7.


Paraneoplastic cerebellar degeneration in a patient with pseudomyxoma peritonei and breast cancer: case report and literature review.

Ardavanis A, Sykoutri D, Kountourakis P, Doufexis D, Korkolis D, Tzerbini H, Skarlatos I, Mosa E, Rigatos G.

In Vivo. 2009 Sep-Oct;23(5):835-8.


Salvage therapy of pretreated advanced breast cancer with bevacizumab and paclitaxel every two weeks: a retrospective case review study.

Ardavanis A, Doufexis D, Kountourakis P, Malliou S, Karagiannis A, Kardara E, Sykoutri D, Charalampia M, Rigatos G.

BMC Cancer. 2009 Sep 23;9:338. doi: 10.1186/1471-2407-9-338.


Defining molecular phenotypes of human papillomavirus-associated oropharyngeal squamous cell carcinoma: validation of three-class hypothesis.

Weinberger PM, Yu Z, Kountourakis P, Sasaki C, Haffty BG, Kowalski D, Merkley MA, Rimm DL, Camp RL, Psyrri A.

Otolaryngol Head Neck Surg. 2009 Sep;141(3):382-9. doi: 10.1016/j.otohns.2009.04.014.


Expression and prognostic significance of kallikrein-related peptidase 8 protein levels in advanced ovarian cancer by using automated quantitative analysis.

Kountourakis P, Psyrri A, Scorilas A, Markakis S, Kowalski D, Camp RL, Diamandis EP, Dimopoulos MA.

Thromb Haemost. 2009 Mar;101(3):541-6.


Concomitant gastric adenocarcinoma and stromal tumor in a woman with polymyalgia rheumatica.

Kountourakis P, Arnogiannaki N, Stavrinides I, Apostolikas N, Rigatos G.

World J Gastroenterol. 2008 Nov 21;14(43):6750-2.


Bevacizumab added to the irinotecan and capecitabine combination for advanced colorectal cancer: a well-tolerated, active and convenient regimen.

Ardavanis A, Kountourakis P, Mantzaris I, Malliou S, Doufexis D, Sykoutri D, Fragos I, Rigatos G.

Anticancer Res. 2008 Sep-Oct;28(5B):3087-92.


Extracellular domain of HER2: a useful marker for the initial workup and follow-up of HER2-positive breast cancer.

Garoufali A, Kyriakou F, Kountourakis P, Yioti I, Malliou S, Nikaki A, Kardara E, Frangos I, Koumna S, Baziotis N, Scorilas A, Ardavanis A.

J BUON. 2008 Jul-Sep;13(3):409-13.


Prognostic value of kallikrein-related peptidase 6 protein expression levels in advanced ovarian cancer evaluated by automated quantitative analysis (AQUA).

Kountourakis P, Psyrri A, Scorilas A, Camp R, Markakis S, Kowalski D, Diamandis EP, Dimopoulos MA.

Cancer Sci. 2008 Nov;99(11):2224-9. doi: 10.1111/j.1349-7006.2008.00942.x. Epub 2008 Oct 9.


A Kaposi's sarcoma complete clinical response after sorafenib administration.

Ardavanis A, Doufexis D, Kountourakis P, Rigatos G.

Ann Oncol. 2008 Sep;19(9):1658-9. doi: 10.1093/annonc/mdn528. Epub 2008 Jul 22. No abstract available.


Sarcomatoid differentiation of renal cell carcinoma: a clinical case with literature review.

Kountourakis P, Kandylis K, Daskalopoulou D, Rigatos G.

J BUON. 2008 Apr-Jun;13(2):281-3.


Trastuzumab plus paclitaxel or docetaxel in HER-2-negative/HER-2 ECD-positive anthracycline- and taxane-refractory advanced breast cancer.

Ardavanis A, Kountourakis P, Kyriakou F, Malliou S, Mantzaris I, Garoufali A, Yiotis I, Scorilas A, Baziotis N, Rigatos G.

Oncologist. 2008 Apr;13(4):361-9. doi: 10.1634/theoncologist.2007-0207.

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