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Items: 1 to 50 of 130

1.

Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians.

Hashimoto K, Kouno T, Ikawa T, Hayatsu N, Miyajima Y, Yabukami H, Terooatea T, Sasaki T, Suzuki T, Valentine M, Pascarella G, Okazaki Y, Suzuki H, Shin JW, Minoda A, Taniuchi I, Okano H, Arai Y, Hirose N, Carninci P.

Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24242-24251. doi: 10.1073/pnas.1907883116. Epub 2019 Nov 12.

2.

C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution.

Kouno T, Moody J, Kwon AT, Shibayama Y, Kato S, Huang Y, Böttcher M, Motakis E, Mendez M, Severin J, Luginbühl J, Abugessaisa I, Hasegawa A, Takizawa S, Arakawa T, Furuno M, Ramalingam N, West J, Suzuki H, Kasukawa T, Lassmann T, Hon CC, Arner E, Carninci P, Plessy C, Shin JW.

Nat Commun. 2019 Jan 21;10(1):360. doi: 10.1038/s41467-018-08126-5.

3.

Carnation I locus contains two chalcone isomerase genes involved in orange flower coloration.

Miyahara T, Sugishita N, Ishida-Dei M, Okamoto E, Kouno T, Cano EA, Sasaki N, Watanabe A, Tasaki K, Nishihara M, Ozeki Y.

Breed Sci. 2018 Sep;68(4):481-487. doi: 10.1270/jsbbs.18029. Epub 2018 Aug 25.

4.

Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence.

Yasui M, Jikuya R, Tatenuma T, Muraoka K, Umemoto S, Kawai M, Kouno T, Kishida T.

Case Rep Urol. 2018 Jun 13;2018:9836154. doi: 10.1155/2018/9836154. eCollection 2018.

5.

Repressed expression of a gene for a basic helix-loop-helix protein causes a white flower phenotype in carnation.

Totsuka A, Okamoto E, Miyahara T, Kouno T, Cano EA, Sasaki N, Watanabe A, Tasaki K, Nishihara M, Ozeki Y.

Breed Sci. 2018 Jan;68(1):139-143. doi: 10.1270/jsbbs.17072. Epub 2018 Feb 27.

6.

CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.

Wakabayashi T, Naito H, Suehiro JI, Lin Y, Kawaji H, Iba T, Kouno T, Ishikawa-Kato S, Furuno M, Takara K, Muramatsu F, Weizhen J, Kidoya H, Ishihara K, Hayashizaki Y, Nishida K, Yoder MC, Takakura N.

Cell Stem Cell. 2018 Mar 1;22(3):384-397.e6. doi: 10.1016/j.stem.2018.01.010. Epub 2018 Feb 8.

7.

SCPortalen: human and mouse single-cell centric database.

Abugessaisa I, Noguchi S, Böttcher M, Hasegawa A, Kouno T, Kato S, Tada Y, Ura H, Abe K, Shin JW, Plessy C, Carninci P, Kasukawa T.

Nucleic Acids Res. 2018 Jan 4;46(D1):D781-D787. doi: 10.1093/nar/gkx949.

8.

The management of extragonadal germ cell tumors.

Kouno T.

Ann Oncol. 2017 Oct;28 Suppl 9:ix52. doi: 10.1093/annonc/mdx627. No abstract available.

9.

A case of cisplatin-refractory advanced pure seminoma showing complete remission after treatment with high-dose carboplatin plus etoposide as fourth-line salvage chemotherapy.

Tachikawa K, Nishiyama N, Muranaka T, Takada K, Murase K, Kouno T, Junji K, Masumori N.

Int Cancer Conf J. 2017 Sep 5;7(1):6-10. doi: 10.1007/s13691-017-0308-8. eCollection 2018 Jan.

10.

The role of acylated-ghrelin in the regulation of sucrose intake.

Kouno T, Akiyama N, Ito T, Fujieda K, Nanchi I, Okuda T, Notoya M, Iwasaki T, Yukioka H.

Endocr J. 2017;64(Suppl.):S21-S23. doi: 10.1507/endocrj.64.S21.

11.

Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.

Kouno T, Silvas TV, Hilbert BJ, Shandilya SMD, Bohn MF, Kelch BA, Royer WE, Somasundaran M, Kurt Yilmaz N, Matsuo H, Schiffer CA.

Nat Commun. 2017 Apr 28;8:15024. doi: 10.1038/ncomms15024.

12.

Microsensors based on a whispering gallery mode in AlGaN microdisks undercut by hydrogen-environment thermal etching.

Kouno T, Sakai M, Takeshima H, Suzuki S, Kikuchi A, Kishino K, Hara K.

Appl Opt. 2017 Apr 20;56(12):3589-3593. doi: 10.1364/AO.56.003589.

PMID:
28430238
13.

Atypical case of Merkel cell carcinoma difficult to diagnose clinically.

Kinoshita Y, Hoashi T, Okazaki S, Kataoka K, Nako T, Mayumi N, Kouno T, Funasaka Y, Ansai SI, Saeki H.

J Dermatol. 2017 Jul;44(7):e158-e159. doi: 10.1111/1346-8138.13815. Epub 2017 Mar 22. No abstract available.

PMID:
28328104
14.

[Neuroendocrine Tumor of the Ampulla of Vater and Gastrointestinal Stromal Tumor of the Duodenum in a Patient with Von Recklinghausen's Disease].

Yamada Y, Shiozawa S, Usui T, Kuhara K, Kouno T, Asaka S, Yamaguchi K, Yokomizo H, Shimakawa T, Yoshimatsu K, Katsube T, Naritaka Y.

Gan To Kagaku Ryoho. 2016 Nov;43(12):2365-2367. Review. Japanese.

PMID:
28133323
15.

Reduced intake of carbohydrate prevents the development of obesity and impaired glucose metabolism in ghrelin O-acyltransferase knockout mice.

Kouno T, Akiyama N, Fujieda K, Nanchi I, Okuda T, Iwasaki T, Oka S, Yukioka H.

Peptides. 2016 Dec;86:145-152. doi: 10.1016/j.peptides.2016.11.003. Epub 2016 Nov 2.

PMID:
27816752
16.

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.

Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T, Motohashi H, Waguri S, Soga T, Yamamoto M, Tanaka K, Komatsu M.

Nat Commun. 2016 Jun 27;7:12030. doi: 10.1038/ncomms12030.

17.

Ghrelin O-acyltransferase knockout mice show resistance to obesity when fed high-sucrose diet.

Kouno T, Akiyama N, Ito T, Okuda T, Nanchi I, Notoya M, Oka S, Yukioka H.

J Endocrinol. 2016 Feb;228(2):115-25. doi: 10.1530/JOE-15-0330. Epub 2015 Dec 8.

PMID:
26645250
18.

[Is the LHRH Agonist Recommended for Fertility Preservation ?].

Kimura K, Iwamoto M, Tanaka S, Watanabe T, Aihara T, Sugimoto T, Miyara K, Hayashi M, Kouno T, Baba S, Kawashima H, Hashimoto N, Uchiyama K.

Gan To Kagaku Ryoho. 2015 Aug;42(8):1019-21. Japanese.

PMID:
26321722
19.

Sensing operations based on hexagonal GaN microdisks acting as whispering-gallery mode optical microcavities.

Kouno T, Sakai M, Kishino K, Hara K.

Opt Lett. 2015 Jun 15;40(12):2866-9. doi: 10.1364/OL.40.002866.

PMID:
26076282
20.

Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G.

Kouno T, Luengas EM, Shigematsu M, Shandilya SM, Zhang J, Chen L, Hara M, Schiffer CA, Harris RS, Matsuo H.

Nat Struct Mol Biol. 2015 Jun;22(6):485-91. doi: 10.1038/nsmb.3033. Epub 2015 May 18.

21.

The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.

Bohn MF, Shandilya SMD, Silvas TV, Nalivaika EA, Kouno T, Kelch BA, Ryder SP, Kurt-Yilmaz N, Somasundaran M, Schiffer CA.

Structure. 2015 May 5;23(5):903-911. doi: 10.1016/j.str.2015.03.016. Epub 2015 Apr 23.

22.

[Impact of exposure dose reduction of radiation treatment planning CT using low tube voltage technique].

Kouno T, Kuga N, Enzaki M, Yamashita Y, Kitazato Y, Shimotabira H, Jinnouchi T, Kusuhara K, Kawamura S.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2015 Apr;71(4):308-15. doi: 10.6009/jjrt.2015_JSRT_71.4.308. Japanese.

23.

[Microtubule depolymerization inhibitor].

Kouno T.

Nihon Rinsho. 2015 Feb;73 Suppl 2:167-73. Japanese. No abstract available.

PMID:
25831745
24.

Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.

Kageyama S, Sou YS, Uemura T, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, Komatsu M.

J Biol Chem. 2014 Sep 5;289(36):24944-55. doi: 10.1074/jbc.M114.580357. Epub 2014 Jul 21.

25.

Importance of isolated anti-hbc in detection of occult hepatitis B virus infection in hemodialysis patients: reply.

Nagakawa O, Miyatomi Y, Shigeta Y, Inayama E, Murakami K, Sakai T, Kouno T, Masai M, Shirai K, Yoshida T.

Ther Apher Dial. 2013 Dec;17(6):644-5. doi: 10.1111/1744-9987.12149. No abstract available.

PMID:
24330564
26.

Temporal dynamics and transcriptional control using single-cell gene expression analysis.

Kouno T, de Hoon M, Mar JC, Tomaru Y, Kawano M, Carninci P, Suzuki H, Hayashizaki Y, Shin JW.

Genome Biol. 2013;14(10):R118.

27.

Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.

Ichimura Y, Waguri S, Sou YS, Kageyama S, Hasegawa J, Ishimura R, Saito T, Yang Y, Kouno T, Fukutomi T, Hoshii T, Hirao A, Takagi K, Mizushima T, Motohashi H, Lee MS, Yoshimori T, Tanaka K, Yamamoto M, Komatsu M.

Mol Cell. 2013 Sep 12;51(5):618-31. doi: 10.1016/j.molcel.2013.08.003. Epub 2013 Sep 5.

28.

Measurement of absorbed dose-to-water for an HDR (192)Ir source with ionization chambers in a sandwich setup.

Araki F, Kouno T, Ohno T, Kakei K, Yoshiyama F, Kawamura S.

Med Phys. 2013 Sep;40(9):092101. doi: 10.1118/1.4816673.

PMID:
24007170
29.

[Dose distribution from kV-cone beam computed tomography in image-guided radiotherapy].

Kouno T, Araki F, Nakaguchi Y, Oono T.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2013 Jul;69(7):753-60. Japanese.

30.

[Comparison of dose calculation algorithms in stereotactic radiation therapy in lung].

Tomiyama Y, Araki F, Kanetake N, Shimohigashi Y, Tominaga H, Sakata J, Oono T, Kouno T, Hioki K.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2013 Jun;69(6):663-8. Japanese.

31.

Occult hepatitis B virus infection in Japanese chronic hemodialysis patients.

Nagakawa O, Miyatomi Y, Shigeta Y, Inayama E, Murakami K, Sakai T, Kouno T, Masai M, Shirai K, Yoshida T.

Ther Apher Dial. 2013 Jun;17(3):289-92. doi: 10.1111/1744-9987.12006. Epub 2013 Jan 21.

PMID:
23735143
32.

Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain.

Bohn MF, Shandilya SM, Albin JS, Kouno T, Anderson BD, McDougle RM, Carpenter MA, Rathore A, Evans L, Davis AN, Zhang J, Lu Y, Somasundaran M, Matsuo H, Harris RS, Schiffer CA.

Structure. 2013 Jun 4;21(6):1042-50. doi: 10.1016/j.str.2013.04.010. Epub 2013 May 16.

33.

Development of multi-planar dose verification by use of a flat panel EPID for intensity-modulated radiation therapy.

Nakaguchi Y, Araki F, Kouno T, Ono T, Hioki K.

Radiol Phys Technol. 2013 Jan;6(1):226-32. doi: 10.1007/s12194-012-0192-z. Epub 2012 Dec 11.

PMID:
23229201
34.

[Quality assurance of respiratory-gated stereotactic body radiation therapy in lung using real-time position management system].

Nakaguchi Y, Araki F, Kouno T, Maruyama M.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2012;68(11):1519-24. Japanese.

35.

[Practical method for six-dimensional online correction system with image guided radiation therapy].

Nakaguchi Y, Araki F, Kouno T, Maruyama M.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2012;68(11):1492-8. Japanese.

36.

Electrochemical direct detection of DNA deamination catalyzed by APOBEC3G.

Chiba J, Kouno T, Aoki S, Sato H, Zhang J, Matsuo H, Inouye M.

Chem Commun (Camb). 2012 Dec 25;48(99):12115-7. doi: 10.1039/c2cc36779c. Epub 2012 Nov 12.

37.

[Comparison of various image guided radiation therapy systems; image-guided localization accuracy and patient throughput].

Takenaga E, Nakaguchi Y, Maruyama M, Nagasue N, Kakei K, Kai Y, Kouno T, Sasaki M, Hashida M.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2012;68(10):1327-32. Japanese.

38.

Multiple regulation of Arabidopsis AtGST11 gene expression by four transcription factors under abiotic stresses.

Kouno T, Ezaki B.

Physiol Plant. 2013 May;148(1):97-104. doi: 10.1111/j.1399-3054.2012.01699.x. Epub 2012 Oct 22.

PMID:
23009097
39.

Structural characterization of a trapped folding intermediate of pyrrolidone carboxyl peptidase from a hyperthermophile.

Mizuguchi M, Takeuchi M, Ohki S, Nabeshima Y, Kouno T, Aizawa T, Demura M, Kawano K, Yutani K.

Biochemistry. 2012 Aug 7;51(31):6089-96. Epub 2012 Jul 25.

PMID:
22799522
40.

[Comparison of dose accuracy between 2D array detectors for pre-treatment IMRT QA].

Nakaguchi Y, Araki F, Saiga S, Kouno T, Maruyama M, Kakei K, Nagasue N, Hashida M.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2012;68(4):443-52. Japanese.

41.

Specific enzyme complex of beta-1,4-galactosyltransferase-II and glucuronyltransferase-P facilitates biosynthesis of N-linked human natural killer-1 (HNK-1) carbohydrate.

Kouno T, Kizuka Y, Nakagawa N, Yoshihara T, Asano M, Oka S.

J Biol Chem. 2011 Sep 9;286(36):31337-46. doi: 10.1074/jbc.M111.233353. Epub 2011 Jul 19.

42.

Small invasive colon cancer with systemic metastasis: a case report.

Matsumoto M, Nakajima T, Kato K, Kouno T, Sakamoto T, Matsuda T, Kushima R, Saito Y.

BMC Gastroenterol. 2011 May 20;11:59. doi: 10.1186/1471-230X-11-59.

43.

Generation of adenosyl radical from S-adenosylmethionine (SAM) in biotin synthase.

Kamachi T, Kouno T, Doitomi K, Yoshizawa K.

J Inorg Biochem. 2011 Jun;105(6):850-7. doi: 10.1016/j.jinorgbio.2011.03.013. Epub 2011 Mar 24.

PMID:
21497584
44.

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komatsu M.

J Cell Biol. 2011 Apr 18;193(2):275-84. doi: 10.1083/jcb.201102031. Epub 2011 Apr 11.

45.

Molybdenum-catalyzed transformation of molecular dinitrogen into silylamine: experimental and DFT study on the remarkable role of ferrocenyldiphosphine ligands.

Tanaka H, Sasada A, Kouno T, Yuki M, Miyake Y, Nakanishi H, Nishibayashi Y, Yoshizawa K.

J Am Chem Soc. 2011 Mar 16;133(10):3498-506. doi: 10.1021/ja109181n. Epub 2011 Feb 22.

PMID:
21341772
46.

FcγR2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer.

Tamura K, Shimizu C, Hojo T, Akashi-Tanaka S, Kinoshita T, Yonemori K, Kouno T, Katsumata N, Ando M, Aogi K, Koizumi F, Nishio K, Fujiwara Y.

Ann Oncol. 2011 Jun;22(6):1302-7. doi: 10.1093/annonc/mdq585. Epub 2010 Nov 25.

47.

The Structure of Physarum polycephalum hemagglutinin I suggests a minimal carbohydrate recognition domain of legume lectin fold.

Kouno T, Watanabe N, Sakai N, Nakamura T, Nabeshima Y, Morita M, Mizuguchi M, Aizawa T, Demura M, Imanaka T, Tanaka I, Kawano K.

J Mol Biol. 2011 Jan 14;405(2):560-9. doi: 10.1016/j.jmb.2010.11.024. Epub 2010 Nov 20.

PMID:
21094650
48.

Second platinum therapy in patients with uterine cervical cancer previously treated with platinum chemotherapy.

Tanioka M, Katsumata N, Yonemori K, Kouno T, Shimizu C, Tamura K, Ando M, Fujiwara Y.

Cancer Chemother Pharmacol. 2011 Aug;68(2):337-42. doi: 10.1007/s00280-010-1494-7. Epub 2010 Oct 26.

PMID:
20976599
49.

Predictors of recurrence in breast cancer patients with a pathologic complete response after neoadjuvant chemotherapy.

Tanioka M, Shimizu C, Yonemori K, Yoshimura K, Tamura K, Kouno T, Ando M, Katsumata N, Tsuda H, Kinoshita T, Fujiwara Y.

Br J Cancer. 2010 Jul 27;103(3):297-302. doi: 10.1038/sj.bjc.6605769. Epub 2010 Jul 6.

50.

The incidence and management of metachronous testicular germ cell tumors in patients with extragonadal germ cell tumors.

Hashimoto K, Fujimoto H, Kouno T, Koseki M, Yonemori K, Hirata T, Yunokawa M, Shimizu C, Katsumata N, Tamura K, Ando M, Takeuchi M, Nakanishi H, Komiyama M, Nakagawa T, Fujiwara Y.

Urol Oncol. 2012 May-Jun;30(3):319-24. doi: 10.1016/j.urolonc.2010.02.008. Epub 2010 May 14.

PMID:
20471872

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