Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 54

1.

Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1): a target for cancer therapeutic intervention?

Jaiswal PK, Koul S, Palanisamy N, Koul HK.

Cancer Cell Int. 2019 Aug 31;19:224. doi: 10.1186/s12935-019-0947-2. eCollection 2019.

2.

Protocadherin 7 is overexpressed in castration resistant prostate cancer and promotes aberrant MEK and AKT signaling.

Shishodia G, Koul S, Koul HK.

Prostate. 2019 Nov;79(15):1739-1751. doi: 10.1002/pros.23898. Epub 2019 Aug 26.

PMID:
31449679
3.

The TLK1-Nek1 axis promotes prostate cancer progression.

Singh V, Jaiswal PK, Ghosh I, Koul HK, Yu X, De Benedetti A.

Cancer Lett. 2019 Jul 1;453:131-141. doi: 10.1016/j.canlet.2019.03.041. Epub 2019 Mar 27.

4.

Reactive oxygen species and cancer: A complex interaction.

Saikolappan S, Kumar B, Shishodia G, Koul S, Koul HK.

Cancer Lett. 2019 Jun 28;452:132-143. doi: 10.1016/j.canlet.2019.03.020. Epub 2019 Mar 21.

PMID:
30905813
5.

Targeting the TLK1/NEK1 DDR axis with Thioridazine suppresses outgrowth of androgen independent prostate tumors.

Singh V, Jaiswal PK, Ghosh I, Koul HK, Yu X, De Benedetti A.

Int J Cancer. 2019 Aug 15;145(4):1055-1067. doi: 10.1002/ijc.32200. Epub 2019 Feb 25.

6.

Prostate-Derived Ets Factor (PDEF) Inhibits Metastasis by Inducing Epithelial/Luminal Phenotype in Prostate Cancer Cells.

Wang F, Koul S, Shanmugam PST, Dong Q, Koul HK.

Mol Cancer Res. 2018 Sep;16(9):1430-1440. doi: 10.1158/1541-7786.MCR-18-0010. Epub 2018 May 30.

7.

Eukaryotic Translation Initiation Factor 4 Gamma 1 (eIF4G1) is upregulated during Prostate cancer progression and modulates cell growth and metastasis.

Jaiswal PK, Koul S, Shanmugam PST, Koul HK.

Sci Rep. 2018 May 10;8(1):7459. doi: 10.1038/s41598-018-25798-7.

8.

Tetrandrine inhibits deregulated cell cycle in pancreatic cancer cells: Differential regulation of p21Cip1/Waf1, p27Kip1 and cyclin D1.

Singh K, Dong Q, TimiriShanmugam PS, Koul S, Koul HK.

Cancer Lett. 2018 Jul 1;425:164-173. doi: 10.1016/j.canlet.2018.03.042. Epub 2018 Mar 30.

PMID:
29605511
9.

Tetrandrine (TET) Induces Death Receptors Apo Trail R1 (DR4) and Apo Trail R2 (DR5) and Sensitizes Prostate Cancer Cells to TRAIL-Induced Apoptosis.

Shishodia G, Koul S, Dong Q, Koul HK.

Mol Cancer Ther. 2018 Jun;17(6):1217-1228. doi: 10.1158/1535-7163.MCT-17-1157. Epub 2018 Mar 16.

10.

Androgen receptor (AR) cistrome in prostate differentiation and cancer progression.

Wang F, Koul HK.

Am J Clin Exp Urol. 2017 Nov 9;5(3):18-24. eCollection 2017.

11.

The transcription factor SPDEF suppresses prostate tumor metastasis.

Steffan JJ, Koul S, Meacham RB, Koul HK.

J Biol Chem. 2016 Sep 23;291(39):20826. doi: 10.1074/jbc.A112.379396. No abstract available.

12.

Partial bladder outlet obstruction in mice may cause E-cadherin repression through hypoxia induced pathway.

Iguchi N, Hou A, Koul HK, Wilcox DT.

J Urol. 2014 Sep;192(3):964-72. doi: 10.1016/j.juro.2014.03.037. Epub 2014 Mar 16.

PMID:
24647082
13.

Oxalate upregulates expression of IL-2Rβ and activates IL-2R signaling in HK-2 cells, a line of human renal epithelial cells.

Koul S, Khandrika L, Pshak TJ, Iguchi N, Pal M, Steffan JJ, Koul HK.

Am J Physiol Renal Physiol. 2014 May 1;306(9):F1039-46. doi: 10.1152/ajprenal.00462.2013. Epub 2014 Feb 12.

14.

Role of p38 MAP Kinase Signal Transduction in Solid Tumors.

Koul HK, Pal M, Koul S.

Genes Cancer. 2013 Sep;4(9-10):342-59. doi: 10.1177/1947601913507951. Review.

15.
16.

Clinical-pathologic correlation between transperineal mapping biopsies of the prostate and three-dimensional reconstruction of prostatectomy specimens.

Crawford ED, Rove KO, Barqawi AB, Maroni PD, Werahera PN, Baer CA, Koul HK, Rove CA, Lucia MS, La Rosa FG.

Prostate. 2013 May;73(7):778-87. doi: 10.1002/pros.22622. Epub 2012 Nov 20.

17.

Genome wide analysis of differentially expressed genes in HK-2 cells, a line of human kidney epithelial cells in response to oxalate.

Koul S, Khandrika L, Meacham RB, Koul HK.

PLoS One. 2012;7(9):e43886. doi: 10.1371/journal.pone.0043886. Epub 2012 Sep 19.

18.

The antioxidant, MnTE-2-PyP, prevents side-effects incurred by prostate cancer irradiation.

Oberley-Deegan RE, Steffan JJ, Rove KO, Pate KM, Weaver MW, Spasojevic I, Frederick B, Raben D, Meacham RB, Crapo JD, Koul HK.

PLoS One. 2012;7(9):e44178. doi: 10.1371/journal.pone.0044178. Epub 2012 Sep 12.

19.

Kidney injury molecule-1 is up-regulated in renal epithelial cells in response to oxalate in vitro and in renal tissues in response to hyperoxaluria in vivo.

Khandrika L, Koul S, Meacham RB, Koul HK.

PLoS One. 2012;7(9):e44174. doi: 10.1371/journal.pone.0044174. Epub 2012 Sep 12.

20.

Role of testosterone in managing advanced prostate cancer.

Rove KO, Debruyne FM, Djavan B, Gomella LG, Koul HK, Lucia MS, Petrylak DP, Shore ND, Stone NN, Crawford ED.

Urology. 2012 Oct;80(4):754-62. doi: 10.1016/j.urology.2012.05.006. Epub 2012 Jul 13. Review.

PMID:
22795376
21.

The transcription factor SPDEF suppresses prostate tumor metastasis.

Steffan JJ, Koul S, Meacham RB, Koul HK.

J Biol Chem. 2012 Aug 24;287(35):29968-78. doi: 10.1074/jbc.M112.379396. Epub 2012 Jul 2. Erratum in: J Biol Chem. 2016 Sep 23;291(39):20826.

22.

Potentiation of mitomycin C tumoricidal activity for transitional cell carcinoma by histone deacetylase inhibitors in vitro.

Deb AA, Wilson SS, Rove KO, Kumar B, Koul S, Lim DD, Meacham RB, Koul HK.

J Urol. 2011 Dec;186(6):2426-33. doi: 10.1016/j.juro.2011.07.107. Epub 2011 Oct 21.

PMID:
22019171
23.

New role for an established drug? Bisphosphonates as potential anticancer agents.

Koul HK, Koul S, Meacham RB.

Prostate Cancer Prostatic Dis. 2012 Jun;15(2):111-9. doi: 10.1038/pcan.2011.41. Epub 2011 Aug 30. Review.

PMID:
21876554
24.

Prostate derived ETS factor (PDEF): a putative tumor metastasis suppressor.

Steffan JJ, Koul HK.

Cancer Lett. 2011 Nov 1;310(1):109-17. doi: 10.1016/j.canlet.2011.06.011. Epub 2011 Jun 29. Review.

PMID:
21764212
25.

The role of inflammation and infection in prostate cancer: Importance in prevention, diagnosis and treatment.

Koul HK, Kumar B, Koul S, Deb AA, Hwa JS, Maroni P, van Bokhoven A, Lucia MS, Kim FJ, Meacham RB.

Drugs Today (Barc). 2010 Dec;46(12):929-43. doi: 10.1358/dot.2010.46.12.1537942. Review.

PMID:
21589950
26.

Loss of PDEF, a prostate-derived Ets factor is associated with aggressive phenotype of prostate cancer: regulation of MMP 9 by PDEF.

Johnson TR, Koul S, Kumar B, Khandrika L, Venezia S, Maroni PD, Meacham RB, Koul HK.

Mol Cancer. 2010 Jun 15;9:148. doi: 10.1186/1476-4598-9-148.

27.

p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity.

Kumar B, Koul S, Petersen J, Khandrika L, Hwa JS, Meacham RB, Wilson S, Koul HK.

Cancer Res. 2010 Jan 15;70(2):832-41. doi: 10.1158/0008-5472.CAN-09-2918. Epub 2010 Jan 12.

28.

Differential effects of MAPKs signaling on the growth of invasive bladder cancer cells.

Kumar B, Sinclair J, Khandrika L, Koul S, Wilson S, Koul HK.

Int J Oncol. 2009 Jun;34(6):1557-64.

PMID:
19424573
29.

Differential effects of valproic acid on growth, proliferation and metastasis in HTB5 and HTB9 bladder cancer cell lines.

Byun SS, Kim FJ, Khandrika L, Kumar B, Koul S, Wilson S, Koul HK.

Cancer Lett. 2009 Aug 28;281(2):196-202. doi: 10.1016/j.canlet.2009.02.045. Epub 2009 Mar 25.

PMID:
19324494
30.

Biochemical alterations in partial bladder outlet obstruction in mice: up-regulation of the mitogen activated protein kinase pathway.

Myers JB, Dall'era JE, Koul S, Kumar B, Khandrika L, Flynn BJ, Koul HK.

J Urol. 2009 Apr;181(4):1926-31. doi: 10.1016/j.juro.2008.11.077. Epub 2009 Feb 23.

PMID:
19237171
31.

Oxidative stress in prostate cancer.

Khandrika L, Kumar B, Koul S, Maroni P, Koul HK.

Cancer Lett. 2009 Sep 18;282(2):125-36. doi: 10.1016/j.canlet.2008.12.011. Epub 2009 Jan 30. Review.

32.

Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1alpha levels contribute to emergence of an aggressive phenotype in prostate cancer.

Khandrika L, Lieberman R, Koul S, Kumar B, Maroni P, Chandhoke R, Meacham RB, Koul HK.

Oncogene. 2009 Mar 5;28(9):1248-60. doi: 10.1038/onc.2008.476. Epub 2009 Jan 19.

33.

Congenital anomalies of the kidney and urinary tract (CAKUT): a current review of cell signaling processes in ureteral development.

Stahl DA, Koul HK, Chacko JK, Mingin GC.

J Pediatr Urol. 2006 Feb;2(1):2-9. doi: 10.1016/j.jpurol.2005.04.006. Epub 2005 Jul 11.

PMID:
18947587
34.

Focal adhesion kinase controls aggressive phenotype of androgen-independent prostate cancer.

Johnson TR, Khandrika L, Kumar B, Venezia S, Koul S, Chandhoke R, Maroni P, Donohue R, Meacham RB, Koul HK.

Mol Cancer Res. 2008 Oct;6(10):1639-48. doi: 10.1158/1541-7786.MCR-08-0052.

35.

Primary culture and characterization of human renal inner medullary collecting duct epithelial cells.

Khandrika L, Kim FJ, Campagna A, Koul S, Meacham RB, Koul HK.

J Urol. 2008 May;179(5):2057-63. doi: 10.1016/j.juro.2008.01.007. Epub 2008 Mar 20.

PMID:
18355855
36.

Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype.

Kumar B, Koul S, Khandrika L, Meacham RB, Koul HK.

Cancer Res. 2008 Mar 15;68(6):1777-85. doi: 10.1158/0008-5472.CAN-07-5259.

37.

Vascular endothelial growth factor (VEGF) gene therapy using a nonviral gene delivery system improves erectile function in a diabetic rat model.

Dall'Era JE, Meacham RB, Mills JN, Koul S, Carlsen SN, Myers JB, Koul HK.

Int J Impot Res. 2008 May-Jun;20(3):307-14. doi: 10.1038/ijir.2008.1. Epub 2008 Feb 14.

PMID:
18273028
38.

Oxalate exposure provokes HSP 70 response in LLC-PK1 cells, a line of renal epithelial cells: protective role of HSP 70 against oxalate toxicity.

Koul S, Huang M, Bhat S, Maroni P, Meacham RB, Koul HK.

Urol Res. 2008 Feb;36(1):1-10. doi: 10.1007/s00240-007-0130-4. Epub 2008 Jan 3.

PMID:
18172632
39.

Penile rehabilitation after radical prostatectomy: important therapy or wishful thinking?

Dall'era JE, Mills JN, Koul HK, Meacham RB.

Rev Urol. 2006 Fall;8(4):209-15.

40.

Oxalate stimulates IL-6 production in HK-2 cells, a line of human renal proximal tubular epithelial cells.

Huang MY, Chaturvedi LS, Koul S, Koul HK.

Kidney Int. 2005 Aug;68(2):497-503.

41.

Oxalate toxicity in cultured mouse inner medullary collecting duct cells.

Maroni PD, Koul S, Chandhoke PS, Meacham RB, Koul HK.

J Urol. 2005 Aug;174(2):757-60.

PMID:
16006971
42.
43.

p42/p44 Mitogen-activated protein kinase signal transduction pathway: a novel target for the treatment of hormone-resistant prostate cancer?

Koul HK, Maroni PD, Meacham RB, Crawford D, Koul S.

Ann N Y Acad Sci. 2004 Dec;1030:243-52. Review.

PMID:
15659803
44.

Effects of oxalate on IMCD cells: a line of mouse inner medullary collecting duct cells.

Maroni PD, Koul S, Meacham RB, Chandhoke PS, Koul HK.

Ann N Y Acad Sci. 2004 Dec;1030:144-9.

45.

Mitogen Activated Protein kinase signal transduction pathways in the prostate.

Maroni PD, Koul S, Meacham RB, Koul HK.

Cell Commun Signal. 2004 Jun 25;2(1):5.

46.
47.

COM crystals activate the p38 mitogen-activated protein kinase signal transduction pathway in renal epithelial cells.

Koul HK, Menon M, Chaturvedi LS, Koul S, Sekhon A, Bhandari A, Huang M.

J Biol Chem. 2002 Sep 27;277(39):36845-52. Epub 2002 Jul 16.

48.

Effects of oxalate on HK-2 cells, a line of proximal tubular epithelial cells from normal human kidney.

Bhandari A, Koul S, Sekhon A, Pramanik SK, Chaturvedi LS, Huang M, Menon M, Koul HK.

J Urol. 2002 Jul;168(1):253-9. Erratum in: J Urol 2002 Oct;168(4 Pt 1):1510.

PMID:
12050552
49.

Effects of oxalate on the re-initiation of DNA synthesis in LLC-PK1 cells do not involve p42/44 MAP kinase activation.

Koul S, Chaturvedi LS, Sekhon A, Bhandari A, Menon M, Koul HK.

Kidney Int. 2002 Feb;61(2):525-33. Erratum in: Kidney Int 2002 Mar;61(3):1197-8.

50.

Oxalate selectively activates p38 mitogen-activated protein kinase and c-Jun N-terminal kinase signal transduction pathways in renal epithelial cells.

Chaturvedi LS, Koul S, Sekhon A, Bhandari A, Menon M, Koul HK.

J Biol Chem. 2002 Apr 12;277(15):13321-30. Epub 2002 Jan 31.

Supplemental Content

Support Center