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Items: 24

1.

High-level transgene expression in induced pluripotent stem cell-derived megakaryocytes: correction of Glanzmann thrombasthenia.

Sullivan SK, Mills JA, Koukouritaki SB, Vo KK, Lyde RB, Paluru P, Zhao G, Zhai L, Sullivan LM, Wang Y, Kishore S, Gharaibeh EZ, Lambert MP, Wilcox DA, French DL, Poncz M, Gadue P.

Blood. 2014 Jan 30;123(5):753-7. doi: 10.1182/blood-2013-10-530725. Epub 2013 Dec 13.

2.

Platelet-targeted gene therapy with human factor VIII establishes haemostasis in dogs with haemophilia A.

Du LM, Nurden P, Nurden AT, Nichols TC, Bellinger DA, Jensen ES, Haberichter SL, Merricks E, Raymer RA, Fang J, Koukouritaki SB, Jacobi PM, Hawkins TB, Cornetta K, Shi Q, Wilcox DA.

Nat Commun. 2013;4:2773. doi: 10.1038/ncomms3773.

3.

Platelet gene therapy improves hemostatic function for integrin alphaIIbbeta3-deficient dogs.

Fang J, Jensen ES, Boudreaux MK, Du LM, Hawkins TB, Koukouritaki SB, Cornetta K, Wilcox DA.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9583-8. doi: 10.1073/pnas.1016394108. Epub 2011 May 23.

4.

Regulatory polymorphisms and their contribution to interindividual differences in the expression of enzymes influencing drug and toxicant disposition.

Hines RN, Koukouritaki SB, Poch MT, Stephens MC.

Drug Metab Rev. 2008;40(2):263-301. doi: 10.1080/03602530801952682 . Review.

PMID:
18464046
5.

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.

Koukouritaki SB, Poch MT, Henderson MC, Siddens LK, Krueger SK, VanDyke JE, Williams DE, Pajewski NM, Wang T, Hines RN.

J Pharmacol Exp Ther. 2007 Jan;320(1):266-73. Epub 2006 Oct 18.

PMID:
17050781
6.

Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: II. Expression and role of flavin-containing monooxygenases and peroxidases.

Vyas PM, Roychowdhury S, Koukouritaki SB, Hines RN, Krueger SK, Williams DE, Nauseef WM, Svensson CK.

J Pharmacol Exp Ther. 2006 Oct;319(1):497-505. Epub 2006 Jul 20.

PMID:
16857727
7.

Developmental expression of aryl, estrogen, and hydroxysteroid sulfotransferases in pre- and postnatal human liver.

Duanmu Z, Weckle A, Koukouritaki SB, Hines RN, Falany JL, Falany CN, Kocarek TA, Runge-Morris M.

J Pharmacol Exp Ther. 2006 Mar;316(3):1310-7. Epub 2005 Dec 9.

PMID:
16339912
8.

Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.

Koukouritaki SB, Hines RN.

Pharmacogenomics. 2005 Dec;6(8):807-22. Review.

PMID:
16296944
9.

Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants.

Koukouritaki SB, Poch MT, Cabacungan ET, McCarver DG, Hines RN.

Mol Pharmacol. 2005 Aug;68(2):383-92. Epub 2005 Apr 27.

PMID:
15858076
10.

Developmental expression of human hepatic CYP2C9 and CYP2C19.

Koukouritaki SB, Manro JR, Marsh SA, Stevens JC, Rettie AE, McCarver DG, Hines RN.

J Pharmacol Exp Ther. 2004 Mar;308(3):965-74. Epub 2003 Nov 21.

PMID:
14634042
11.

Human hepatic CYP2E1 expression during development.

Johnsrud EK, Koukouritaki SB, Divakaran K, Brunengraber LL, Hines RN, McCarver DG.

J Pharmacol Exp Ther. 2003 Oct;307(1):402-7. Erratum in: J Pharmacol Exp Ther. 2004 Apr;309(1):439.

PMID:
14500779
12.

Developmental expression of the major human hepatic CYP3A enzymes.

Stevens JC, Hines RN, Gu C, Koukouritaki SB, Manro JR, Tandler PJ, Zaya MJ.

J Pharmacol Exp Ther. 2003 Nov;307(2):573-82. Epub 2003 Sep 15.

PMID:
12975492
13.

Genetic variability at the human FMO1 locus: significance of a basal promoter yin yang 1 element polymorphism (FMO1*6).

Hines RN, Luo Z, Hopp KA, Cabacungan ET, Koukouritaki SB, McCarver DG.

J Pharmacol Exp Ther. 2003 Sep;306(3):1210-8. Epub 2003 Jun 26.

PMID:
12829732
14.

Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression.

Koukouritaki SB, Simpson P, Yeung CK, Rettie AE, Hines RN.

Pediatr Res. 2002 Feb;51(2):236-43.

PMID:
11809920
16.

Heme oxygenase-1 induction attenuates inducible nitric oxide synthase expression and proteinuria in glomerulonephritis.

Datta PK, Koukouritaki SB, Hopp KA, Lianos EA.

J Am Soc Nephrol. 1999 Dec;10(12):2540-50.

17.

Enhanced expression of the cytoskeleton-associated proteins paxillin and focal adhesion kinase in glomerular immune injury.

Koukouritaki SB, Tamizuddin A, Lianos EA.

J Lab Clin Med. 1999 Aug;134(2):173-9.

PMID:
10444032
18.

TNF-alpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase.

Koukouritaki SB, Vardaki EA, Papakonstanti EA, Lianos E, Stournaras C, Emmanouel DS.

Mol Med. 1999 Jun;5(6):382-92.

19.

Glucocorticoid effect on human mesangial cell cytoskeletal proteins.

Koukouritaki SB, Lianos EA.

J Lab Clin Med. 1999 Apr;133(4):378-83.

PMID:
10218769
20.

Enhanced expression of the cytoskeletal-associated protein, paxillin, in experimental nephrotic syndrome.

Koukouritaki SB, Tamizuddin A, Lianos EA.

J Investig Med. 1998 Aug;46(6):284-9.

PMID:
9737090
21.

Dexamethasone induces rapid actin assembly in human endometrial cells without affecting its synthesis.

Koukouritaki SB, Margioris AN, Gravanis A, Hartig R, Stournaras C.

J Cell Biochem. 1997 Jun 15;65(4):492-500.

PMID:
9178099
22.

Altered actin polymerization dynamics in various malignant cell types: evidence for differential sensitivity to cytochalasin B.

Stournaras C, Stiakaki E, Koukouritaki SB, Theodoropoulos PA, Kalmanti M, Fostinis Y, Gravanis A.

Biochem Pharmacol. 1996 Nov 8;52(9):1339-46.

PMID:
8937443
23.

Dexamethasone alters rapidly actin polymerization dynamics in human endometrial cells: evidence for nongenomic actions involving cAMP turnover.

Koukouritaki SB, Theodoropoulos PA, Margioris AN, Gravanis A, Stournaras C.

J Cell Biochem. 1996 Aug;62(2):251-61.

PMID:
8844405
24.

Differences in the G/total actin ratio and microfilament stability between normal and malignant human keratinocytes.

Katsantonis J, Tosca A, Koukouritaki SB, Theodoropoulos PA, Gravanis A, Stournaras C.

Cell Biochem Funct. 1994 Dec;12(4):267-74.

PMID:
7834816

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