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Items: 9


Binding of eIF3 in complex with eIF5 and eIF1 to the 40S ribosomal subunit is accompanied by dramatic structural changes.

Zeman J, Itoh Y, Kukačka Z, Rosůlek M, Kavan D, Kouba T, Jansen ME, Mohammad MP, Novák P, Valášek LS.

Nucleic Acids Res. 2019 Jul 10. pii: gkz570. doi: 10.1093/nar/gkz570. [Epub ahead of print]


Structural snapshots of actively transcribing influenza polymerase.

Kouba T, Drncová P, Cusack S.

Nat Struct Mol Biol. 2019 Jun;26(6):460-470. doi: 10.1038/s41594-019-0232-z. Epub 2019 Jun 3.


The Core and Holoenzyme Forms of RNA Polymerase from Mycobacterium smegmatis.

Kouba T, Pospíšil J, Hnilicová J, Šanderová H, Barvík I, Krásný L.

J Bacteriol. 2019 Jan 28;201(4). pii: e00583-18. doi: 10.1128/JB.00583-18. Print 2019 Feb 15.


Structures of closed and open conformations of dimeric human ATM.

Baretić D, Pollard HK, Fisher DI, Johnson CM, Santhanam B, Truman CM, Kouba T, Fersht AR, Phillips C, Williams RL.

Sci Adv. 2017 May 10;3(5):e1700933. doi: 10.1126/sciadv.1700933. eCollection 2017 May.


Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes.

Khoshnevis S, Gunišová S, Vlčková V, Kouba T, Neumann P, Beznosková P, Ficner R, Valášek LS.

Nucleic Acids Res. 2014 Apr;42(6):4123-39. doi: 10.1093/nar/gkt1369. Epub 2014 Jan 13.


Small ribosomal protein RPS0 stimulates translation initiation by mediating 40S-binding of eIF3 via its direct contact with the eIF3a/TIF32 subunit.

Kouba T, Dányi I, Gunišová S, Munzarová V, Vlčková V, Cuchalová L, Neueder A, Milkereit P, Valášek LS.

PLoS One. 2012;7(7):e40464. doi: 10.1371/journal.pone.0040464. Epub 2012 Jul 5.


The eIF3c/NIP1 PCI domain interacts with RNA and RACK1/ASC1 and promotes assembly of translation preinitiation complexes.

Kouba T, Rutkai E, Karásková M, Valášek L.

Nucleic Acids Res. 2012 Mar;40(6):2683-99. doi: 10.1093/nar/gkr1083. Epub 2011 Nov 28.


Rapid changes in gene expression: DNA determinants of promoter regulation by the concentration of the transcription initiating NTP in Bacillus subtilis.

Sojka L, Kouba T, Barvík I, Sanderová H, Maderová Z, Jonák J, Krásny L.

Nucleic Acids Res. 2011 Jun;39(11):4598-611. doi: 10.1093/nar/gkr032. Epub 2011 Feb 7.


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