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Items: 1 to 50 of 52

1.

Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese.

Kou I, Otomo N, Takeda K, Momozawa Y, Lu HF, Kubo M, Kamatani Y, Ogura Y, Takahashi Y, Nakajima M, Minami S, Uno K, Kawakami N, Ito M, Yonezawa I, Watanabe K, Kaito T, Yanagida H, Taneichi H, Harimaya K, Taniguchi Y, Shigematsu H, Iida T, Demura S, Sugawara R, Fujita N, Yagi M, Okada E, Hosogane N, Kono K, Nakamura M, Chiba K, Kotani T, Sakuma T, Akazawa T, Suzuki T, Nishida K, Kakutani K, Tsuji T, Sudo H, Iwata A, Sato T, Inami S, Matsumoto M, Terao C, Watanabe K, Ikegawa S.

Nat Commun. 2019 Aug 15;10(1):3685. doi: 10.1038/s41467-019-11596-w.

2.

Association of Susceptibility Genes for Adolescent Idiopathic Scoliosis and Intervertebral Disc Degeneration With Adult Spinal Deformity.

Takeda K, Kou I, Hosogane N, Otomo N, Yagi M, Kaneko S, Kono H, Ishikawa M, Takahashi Y, Ikegami T, Nojiri K, Okada E, Funao H, Okuyama K, Tsuji T, Fujita N, Nagoshi N, Tsuji O, Ogura Y, Ishii K, Nakamura M, Matsumoto M, Ikegawa S, Watanabe K.

Spine (Phila Pa 1976). 2019 Dec 1;44(23):1623-1629. doi: 10.1097/BRS.0000000000003179.

PMID:
31365516
3.

Bi-allelic loss of function variants of TBX6 causes a spectrum of malformation of spine and rib including congenital scoliosis and spondylocostal dysostosis.

Otomo N, Takeda K, Kawai S, Kou I, Guo L, Osawa M, Alev C, Kawakami N, Miyake N, Matsumoto N, Yasuhiko Y, Kotani T, Suzuki T, Uno K, Sudo H, Inami S, Taneichi H, Shigematsu H, Watanabe K, Yonezawa I, Sugawara R, Taniguchi Y, Minami S, Kaneko K, Nakamura M, Matsumoto M, Toguchida J, Watanabe K, Ikegawa S.

J Med Genet. 2019 Sep;56(9):622-628. doi: 10.1136/jmedgenet-2018-105920. Epub 2019 Apr 22.

PMID:
31015262
4.

A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis.

Takeda K, Kou I, Otomo N, Grauers A, Fan YH, Ogura Y, Takahashi Y, Momozawa Y, Einarsdottir E, Kere J; Japan Scoliosis Clinical Research Group (JSCRG), Matsumoto M, Qiu Y, Song YQ, Gerdhem P, Watanabe K, Ikegawa S.

J Hum Genet. 2019 May;64(5):493-498. doi: 10.1038/s10038-019-0575-7. Epub 2019 Feb 21.

PMID:
30787423
5.

Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci.

Khanshour AM, Kou I, Fan Y, Einarsdottir E, Makki N, Kidane YH, Kere J, Grauers A, Johnson TA, Paria N, Patel C, Singhania R, Kamiya N, Takeda K, Otomo N, Watanabe K, Luk KDK, Cheung KMC, Herring JA, Rios JJ, Ahituv N, Gerdhem P, Gurnett CA, Song YQ, Ikegawa S, Wise CA.

Hum Mol Genet. 2018 Nov 15;27(22):3986-3998. doi: 10.1093/hmg/ddy306.

6.

Screening of known disease genes in congenital scoliosis.

Takeda K, Kou I, Mizumoto S, Yamada S, Kawakami N, Nakajima M, Otomo N, Ogura Y, Miyake N, Matsumoto N, Kotani T, Sudo H, Yonezawa I, Uno K, Taneichi H, Watanabe K, Shigematsu H, Sugawara R, Taniguchi Y, Minami S, Nakamura M, Matsumoto M; Japan Early Onset Scoliosis Research Group, Watanabe K, Ikegawa S.

Mol Genet Genomic Med. 2018 Nov;6(6):966-974. doi: 10.1002/mgg3.466. Epub 2018 Sep 9.

7.

A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis.

Kou I, Watanabe K, Takahashi Y, Momozawa Y, Khanshour A, Grauers A, Zhou H, Liu G, Fan YH, Takeda K, Ogura Y, Zhou T, Iwasaki Y, Kubo M, Wu Z, Matsumoto M; Japan Scoliosis Clinical Research Group (JSCRG); Texas Scottish Rite Hospital for Children Clinical Group (TSRHCCG), Einarsdottir E, Kere J, Huang D, Qiu G, Qiu Y, Wise CA, Song YQ, Wu N, Su P, Gerdhem P, Ikegawa S.

Sci Rep. 2018 Aug 1;8(1):11575. doi: 10.1038/s41598-018-29011-7.

8.

An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis.

Ogura Y, Takeda K, Kou I, Khanshour A, Grauers A, Zhou H, Liu G, Fan YH, Zhou T, Wu Z, Takahashi Y, Matsumoto M; Japan Scoliosis Clinical Research Group (JSCRG); Texas Scottish Rite Hospital for Children Clinical Group (TSRHCCG), Einarsdottir E, Kere J, Huang D, Qiu G, Xu L, Qiu Y, Wise CA, Song YQ, Wu N, Su P, Gerdhem P, Watanabe K, Ikegawa S.

Sci Rep. 2018 Mar 16;8(1):4730. doi: 10.1038/s41598-018-22552-x.

9.

CELSR2 is a candidate susceptibility gene in idiopathic scoliosis.

Einarsdottir E, Grauers A, Wang J, Jiao H, Escher SA, Danielsson A, Simony A, Andersen M, Christensen SB, Åkesson K, Kou I, Khanshour AM, Ohlin A, Wise C, Ikegawa S, Kere J, Gerdhem P.

PLoS One. 2017 Dec 14;12(12):e0189591. doi: 10.1371/journal.pone.0189591. eCollection 2017.

10.

A functional variant in MIR4300HG, the host gene of microRNA MIR4300 is associated with progression of adolescent idiopathic scoliosis.

Ogura Y, Kou I, Takahashi Y, Takeda K, Minami S, Kawakami N, Uno K, Ito M, Yonezawa I, Kaito T, Yanagida H, Watanabe K, Taneichi H, Harimaya K, Taniguchi Y, Kotani T, Tsuji T, Suzuki T, Sudo H, Fujita N, Yagi M, Chiba K, Kubo M, Kamatani Y, Nakamura M, Matsumoto M; Japan Scoliosis Clinical Research Group, Watanabe K, Ikegawa S; Japan Scoliosis Clinical Research Group.

Hum Mol Genet. 2017 Oct 15;26(20):4086-4092. doi: 10.1093/hmg/ddx291.

PMID:
29016859
11.

Response to Lefebvre et al.

Takeda K, Kou I, Kawakami N, Yasuhiko Y, Ogura Y, Imagawa E, Miyake N, Matsumoto N, Sudo H, Kotani T; Japan Early Onset Scoliosis Research Group, Nakamura M, Matsumoto M, Watanabe K, Ikegawa S.

Clin Genet. 2017 Nov;92(5):563-564. doi: 10.1111/cge.13011.

PMID:
28990171
12.

A Replication Study for the Association of rs11190870 With Curve Severity in Adolescent Idiopathic Scoliosis in Japanese.

Takahashi Y, Kou I, Ogura Y, Miyake A, Takeda K, Nakajima M, Minami S, Kawakami N, Uno K, Ito M, Yonezawa I, Kaito T, Yanagida H, Watanabe K, Taneichi H, Harimaya K, Taniguchi Y, Kotani T, Tsuji T, Suzuki T, Sudo H, Fujita N, Yagi M, Chiba K, Kono K, Sakuma T, Akazawa T, Nishida K, Kakutani K, Shigematsu H, Iida T, Demura S, Hosogane N, Okada E, Nakamura M, Matsumoto M, Watanabe K, Ikegawa S.

Spine (Phila Pa 1976). 2018 May 15;43(10):688-692. doi: 10.1097/BRS.0000000000002413.

PMID:
28902104
13.

Compound Heterozygosity for Null Mutations and a Common Hypomorphic Risk Haplotype in TBX6 Causes Congenital Scoliosis.

Takeda K, Kou I, Kawakami N, Iida A, Nakajima M, Ogura Y, Imagawa E, Miyake N, Matsumoto N, Yasuhiko Y, Sudo H, Kotani T; Japan Early Onset Scoliosis Research Group, Nakamura M, Matsumoto M, Watanabe K, Ikegawa S.

Hum Mutat. 2017 Mar;38(3):317-323. doi: 10.1002/humu.23168. Epub 2017 Jan 18.

PMID:
28054739
14.

Identification and Functional Characterization of RSPO2 as a Susceptibility Gene for Ossification of the Posterior Longitudinal Ligament of the Spine.

Nakajima M, Kou I, Ohashi H; Genetic Study Group of the Investigation Committee on the Ossification of Spinal Ligaments, Ikegawa S.

Am J Hum Genet. 2016 Jul 7;99(1):202-7. doi: 10.1016/j.ajhg.2016.05.018. Epub 2016 Jun 30.

15.

[Genome-wide association study for adolescent idiopathic scoliosis].

Ogura Y, Kou I; Japan Scoliosis Clinical Research Group, Scoliosis J, Matsumoto M, Watanabe K, Ikegawa S.

Clin Calcium. 2016 Apr;26(4):553-60. doi: CliCa1604553500. Review. Japanese.

PMID:
27013625
16.

Axial Spondylometaphyseal Dysplasia Is Caused by C21orf2 Mutations.

Wang Z, Iida A, Miyake N, Nishiguchi KM, Fujita K, Nakazawa T, Alswaid A, Albalwi MA, Kim OH, Cho TJ, Lim GY, Isidor B, David A, Rustad CF, Merckoll E, Westvik J, Stattin EL, Grigelioniene G, Kou I, Nakajima M, Ohashi H, Smithson S, Matsumoto N, Nishimura G, Ikegawa S.

PLoS One. 2016 Mar 14;11(3):e0150555. doi: 10.1371/journal.pone.0150555. eCollection 2016.

17.

Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation.

Guo L, Yamashita H, Kou I, Takimoto A, Meguro-Horike M, Horike S, Sakuma T, Miura S, Adachi T, Yamamoto T, Ikegawa S, Hiraki Y, Shukunami C.

PLoS Genet. 2016 Jan 28;12(1):e1005802. doi: 10.1371/journal.pgen.1005802. eCollection 2016 Jan.

18.

Identification of HOXD4 Mutations in Spinal Extradural Arachnoid Cyst.

Ogura Y, Miyake N, Kou I, Iida A, Nakajima M, Takeda K, Fujibayashi S, Shiina M, Okada E, Toyama Y, Iwanami A, Ishii K, Ogata K, Asahara H, Matsumoto N, Nakamura M, Matsumoto M, Ikegawa S.

PLoS One. 2015 Nov 6;10(11):e0142126. doi: 10.1371/journal.pone.0142126. eCollection 2015.

19.

Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin-Siris syndrome.

Hempel A, Pagnamenta AT, Blyth M, Mansour S, McConnell V, Kou I, Ikegawa S, Tsurusaki Y, Matsumoto N, Lo-Castro A, Plessis G, Albrecht B, Battaglia A, Taylor JC, Howard MF, Keays D, Sohal AS; DDD Collaboration, Kühl SJ, Kini U, McNeill A.

J Med Genet. 2016 Mar;53(3):152-62. doi: 10.1136/jmedgenet-2015-103393. Epub 2015 Nov 5.

20.

A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis.

Ogura Y, Kou I, Miura S, Takahashi A, Xu L, Takeda K, Takahashi Y, Kono K, Kawakami N, Uno K, Ito M, Minami S, Yonezawa I, Yanagida H, Taneichi H, Zhu Z, Tsuji T, Suzuki T, Sudo H, Kotani T, Watanabe K, Hosogane N, Okada E, Iida A, Nakajima M, Sudo A, Chiba K, Hiraki Y, Toyama Y, Qiu Y, Shukunami C, Kamatani Y, Kubo M, Matsumoto M, Ikegawa S.

Am J Hum Genet. 2015 Aug 6;97(2):337-42. doi: 10.1016/j.ajhg.2015.06.012. Epub 2015 Jul 23.

21.

A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females.

Sharma S, Londono D, Eckalbar WL, Gao X, Zhang D, Mauldin K, Kou I, Takahashi A, Matsumoto M, Kamiya N, Murphy KK, Cornelia R; TSRHC Scoliosis Clinical Group; Japan Scoliosis Clinical Research Group, Herring JA, Burns D, Ahituv N, Ikegawa S, Gordon D, Wise CA.

Nat Commun. 2015 Mar 18;6:6452. doi: 10.1038/ncomms7452.

22.

Influence of various superhydrophilic treatments of titanium on the initial attachment, proliferation, and differentiation of osteoblast-like cells.

Yamamura K, Miura T, Kou I, Muramatsu T, Furusawa M, Yoshinari M.

Dent Mater J. 2015;34(1):120-7. doi: 10.4012/dmj.2014-076. Epub 2015 Jan 17.

23.

A novel FOXC2 mutation in spinal extradural arachnoid cyst.

Ogura Y, Fujibayashi S, Iida A, Kou I, Nakajima M, Okada E, Toyama Y, Iwanami A, Ishii K, Nakamura M, Matsumoto M, Ikegawa S.

Hum Genome Var. 2015 Sep 17;2:15032. doi: 10.1038/hgv.2015.32. eCollection 2015.

24.

De novo SOX11 mutations cause Coffin-Siris syndrome.

Tsurusaki Y, Koshimizu E, Ohashi H, Phadke S, Kou I, Shiina M, Suzuki T, Okamoto N, Imamura S, Yamashita M, Watanabe S, Yoshiura K, Kodera H, Miyatake S, Nakashima M, Saitsu H, Ogata K, Ikegawa S, Miyake N, Matsumoto N.

Nat Commun. 2014 Jun 2;5:4011. doi: 10.1038/ncomms5011.

PMID:
24886874
25.

A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups.

Londono D, Kou I, Johnson TA, Sharma S, Ogura Y, Tsunoda T, Takahashi A, Matsumoto M, Herring JA, Lam TP, Wang X, Tam EM, Song YQ, Fan YH, Chan D, Cheah KS, Qiu X, Jiang H, Huang D; Japanese Scoliosis Clinical Research Group, TSRHC IS Clinical Group, International Consortium for Scoliosis Genetics, Su P, Sham P, Cheung KM, Luk KD, Gordon D, Qiu Y, Cheng J, Tang N, Ikegawa S, Wise CA.

J Med Genet. 2014 Jun;51(6):401-6. doi: 10.1136/jmedgenet-2013-102067. Epub 2014 Apr 10.

PMID:
24721834
26.

FOXC2 mutations in familial and sporadic spinal extradural arachnoid cyst.

Ogura Y, Yabuki S, Iida A, Kou I, Nakajima M, Kano H, Shiina M, Kikuchi S, Toyama Y, Ogata K, Nakamura M, Matsumoto M, Ikegawa S.

PLoS One. 2013 Nov 22;8(11):e80548. doi: 10.1371/journal.pone.0080548. eCollection 2013.

27.

Advanced composite of large cell neuroendocrine carcinoma and squamous cell carcinoma: a case report of uterine cervical cancer in a virgin woman.

Murakami R, Kou I, Date K, Nakayama H.

Case Rep Obstet Gynecol. 2013;2013:921384. doi: 10.1155/2013/921384. Epub 2013 Aug 24.

28.

Identification of a susceptibility locus for severe adolescent idiopathic scoliosis on chromosome 17q24.3.

Miyake A, Kou I, Takahashi Y, Johnson TA, Ogura Y, Dai J, Qiu X, Takahashi A, Jiang H, Yan H, Kono K, Kawakami N, Uno K, Ito M, Minami S, Yanagida H, Taneichi H, Hosono N, Tsuji T, Suzuki T, Sudo H, Kotani T, Yonezawa I, Kubo M, Tsunoda T, Watanabe K, Chiba K, Toyama Y, Qiu Y, Matsumoto M, Ikegawa S.

PLoS One. 2013 Sep 4;8(9):e72802. doi: 10.1371/journal.pone.0072802. eCollection 2013.

29.

Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis.

Kou I, Takahashi Y, Johnson TA, Takahashi A, Guo L, Dai J, Qiu X, Sharma S, Takimoto A, Ogura Y, Jiang H, Yan H, Kono K, Kawakami N, Uno K, Ito M, Minami S, Yanagida H, Taneichi H, Hosono N, Tsuji T, Suzuki T, Sudo H, Kotani T, Yonezawa I, Londono D, Gordon D, Herring JA, Watanabe K, Chiba K, Kamatani N, Jiang Q, Hiraki Y, Kubo M, Toyama Y, Tsunoda T, Wise CA, Qiu Y, Shukunami C, Matsumoto M, Ikegawa S.

Nat Genet. 2013 Jun;45(6):676-9. doi: 10.1038/ng.2639. Epub 2013 May 12.

PMID:
23666238
30.

A replication study for association of 53 single nucleotide polymorphisms in a scoliosis prognostic test with progression of adolescent idiopathic scoliosis in Japanese.

Ogura Y, Takahashi Y, Kou I, Nakajima M, Kono K, Kawakami N, Uno K, Ito M, Minami S, Yanagida H, Taneichi H, Yonezawa I, Tsuji T, Suzuki T, Sudo H, Kotani T, Watanabe K, Chiba K, Toyama Y, Matsumoto M, Ikegawa S.

Spine (Phila Pa 1976). 2013 Jul 15;38(16):1375-9. doi: 10.1097/BRS.0b013e3182947d21.

PMID:
23591653
31.

Meta-analysis identifies a MECOM gene as a novel predisposing factor of osteoporotic fracture.

Hwang JY, Lee SH, Go MJ, Kim BJ, Kou I, Ikegawa S, Guo Y, Deng HW, Raychaudhuri S, Kim YJ, Oh JH, Kim Y, Moon S, Kim DJ, Koo H, Cha MJ, Lee MH, Yun JY, Yoo HS, Kang YA, Cho EH, Kim SW, Oh KW, Kang MI, Son HY, Kim SY, Kim GS, Han BG, Cho YS, Cho MC, Lee JY, Koh JM.

J Med Genet. 2013 Apr;50(4):212-9. doi: 10.1136/jmedgenet-2012-101156. Epub 2013 Jan 24.

32.

Association of the formiminotransferase N-terminal sub-domain containing gene and thrombospondin, type 1, domain-containing 7A gene with the prevalence of vertebral fracture in 2427 consecutive autopsy cases.

Zhou H, Mori S, Kou I, Fuku N, Naka Mieno M, Honma N, Arai T, Sawabe M, Tanaka M, Ikegawa S, Ito H.

J Hum Genet. 2013 Feb;58(2):109-12. doi: 10.1038/jhg.2012.145. Epub 2013 Jan 10.

PMID:
23303384
33.

A replication study for association of 5 single nucleotide polymorphisms with curve progression of adolescent idiopathic scoliosis in Japanese patients.

Ogura Y, Takahashi Y, Kou I, Nakajima M, Kono K, Kawakami N, Uno K, Ito M, Minami S, Yanagida H, Taneichi H, Yonezawa I, Tsuji T, Suzuki T, Sudo H, Kotani T, Watanabe K, Chiba K, Toyama Y, Matsumoto M, Ikegawa S.

Spine (Phila Pa 1976). 2013 Apr 1;38(7):571-5. doi: 10.1097/BRS.0b013e3182761535.

PMID:
23038618
34.

SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese.

Fan YH, Song YQ, Chan D, Takahashi Y, Ikegawa S, Matsumoto M, Kou I, Cheah KS, Sham P, Cheung KM, Luk KD.

J Hum Genet. 2012 Apr;57(4):244-6. doi: 10.1038/jhg.2012.11. Epub 2012 Feb 2.

PMID:
22301463
35.

A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis.

Takahashi Y, Kou I, Takahashi A, Johnson TA, Kono K, Kawakami N, Uno K, Ito M, Minami S, Yanagida H, Taneichi H, Tsuji T, Suzuki T, Sudo H, Kotani T, Watanabe K, Chiba K, Hosono N, Kamatani N, Tsunoda T, Toyama Y, Kubo M, Matsumoto M, Ikegawa S.

Nat Genet. 2011 Oct 23;43(12):1237-40. doi: 10.1038/ng.974.

PMID:
22019779
36.

Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.

Kou I, Takahashi A, Urano T, Fukui N, Ito H, Ozaki K, Tanaka T, Hosoi T, Shiraki M, Inoue S, Nakamura Y, Kamatani N, Kubo M, Mori S, Ikegawa S.

PLoS One. 2011 May 6;6(5):e19641. doi: 10.1371/journal.pone.0019641.

37.

Asporin expression is highly regulated in human chondrocytes.

Duval E, Bigot N, Hervieu M, Kou I, Leclercq S, Galéra P, Boumediene K, Baugé C.

Mol Med. 2011;17(7-8):816-23. doi: 10.2119/molmed.2011.00052. Epub 2011 Apr 25.

38.

New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.

Nakajima M, Takahashi A, Kou I, Rodriguez-Fontenla C, Gomez-Reino JJ, Furuichi T, Dai J, Sudo A, Uchida A, Fukui N, Kubo M, Kamatani N, Tsunoda T, Malizos KN, Tsezou A, Gonzalez A, Nakamura Y, Ikegawa S.

PLoS One. 2010 Mar 18;5(3):e9723. doi: 10.1371/journal.pone.0009723.

39.

Binding characteristics of the osteoarthritis-associated protein asporin.

Kou I, Nakajima M, Ikegawa S.

J Bone Miner Metab. 2010 Jul;28(4):395-402. doi: 10.1007/s00774-009-0145-8. Epub 2010 Jan 7.

PMID:
20052601
40.

Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.

Murakami T, Saito A, Hino S, Kondo S, Kanemoto S, Chihara K, Sekiya H, Tsumagari K, Ochiai K, Yoshinaga K, Saitoh M, Nishimura R, Yoneda T, Kou I, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Wanaka A, Imaizumi K.

Nat Cell Biol. 2009 Oct;11(10):1205-11. doi: 10.1038/ncb1963. Epub 2009 Sep 20.

PMID:
19767743
41.

Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis.

Mori S, Kou I, Sato H, Emi M, Ito H, Hosoi T, Ikegawa S.

J Bone Miner Metab. 2009;27(2):213-6. doi: 10.1007/s00774-008-0031-9. Epub 2009 Jan 27.

PMID:
19172221
42.

Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.

Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, Smith D, Luk KD, Huang QY, Mori S, Sham PC, Kung AW.

Hum Mol Genet. 2009 Feb 15;18(4):679-87. doi: 10.1093/hmg/ddn397. Epub 2008 Dec 8.

PMID:
19064610
43.

Association of genetic variations of genes encoding thrombospondin, type 1, domain-containing 4 and 7A with low bone mineral density in Japanese women with osteoporosis.

Mori S, Kou I, Sato H, Emi M, Ito H, Hosoi T, Ikegawa S.

J Hum Genet. 2008;53(8):694-7. doi: 10.1007/s10038-008-0300-4. Epub 2008 May 17.

PMID:
18488137
44.

Mechanisms for asporin function and regulation in articular cartilage.

Nakajima M, Kizawa H, Saitoh M, Kou I, Miyazono K, Ikegawa S.

J Biol Chem. 2007 Nov 2;282(44):32185-92. Epub 2007 Sep 7.

45.

Expression and regulation of the osteoarthritis-associated protein asporin.

Kou I, Nakajima M, Ikegawa S.

J Biol Chem. 2007 Nov 2;282(44):32193-9. Epub 2007 Sep 5.

46.

An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis.

Kizawa H, Kou I, Iida A, Sudo A, Miyamoto Y, Fukuda A, Mabuchi A, Kotani A, Kawakami A, Yamamoto S, Uchida A, Nakamura K, Notoya K, Nakamura Y, Ikegawa S.

Nat Genet. 2005 Feb;37(2):138-44. Epub 2005 Jan 9.

PMID:
15640800
47.

The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.

Ikeda T, Kamekura S, Mabuchi A, Kou I, Seki S, Takato T, Nakamura K, Kawaguchi H, Ikegawa S, Chung UI.

Arthritis Rheum. 2004 Nov;50(11):3561-73.

48.

SOX9-dependent and -independent transcriptional regulation of human cartilage link protein.

Kou I, Ikegawa S.

J Biol Chem. 2004 Dec 3;279(49):50942-8. Epub 2004 Sep 28.

49.

Influence of 26-hydroxycholesterol on the composition and function of gel-filtered platelets.

Kou IL, Pikul J, Kummerow FA.

J Am Coll Nutr. 1991 Apr;10(2):114-22.

PMID:
2030252
50.

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