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Items: 49

1.

Dectin-2 Is a C-Type Lectin Receptor that Recognizes Pneumocystis and Participates in Innate Immune Responses.

Kottom TJ, Hebrink DM, Jenson PE, Marsolek PL, Wüthrich M, Wang H, Klein B, Yamasaki S, Limper AH.

Am J Respir Cell Mol Biol. 2018 Feb;58(2):232-240. doi: 10.1165/rcmb.2016-0335OC.

PMID:
28886250
2.

The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection.

Kottom TJ, Hebrink DM, Jenson PE, Nandakumar V, Wüthrich M, Wang H, Klein B, Yamasaki S, Lepenies B, Limper AH.

J Immunol. 2017 May 1;198(9):3515-3525. doi: 10.4049/jimmunol.1600744. Epub 2017 Mar 15.

3.

Characterization of N-Acetylglucosamine Biosynthesis in Pneumocystis species. A New Potential Target for Therapy.

Kottom TJ, Hebrink DM, Jenson PE, Ramirez-Prado JH, Limper AH.

Am J Respir Cell Mol Biol. 2017 Feb;56(2):213-222. doi: 10.1165/rcmb.2016-0155OC.

4.

Evidence for a Pneumocystis carinii Flo8-like transcription factor: insights into organism adhesion.

Kottom TJ, Limper AH.

Med Microbiol Immunol. 2016 Feb;205(1):73-84. doi: 10.1007/s00430-015-0428-8. Epub 2015 Jul 28.

5.

Pathobiology of Pneumocystis pneumonia: life cycle, cell wall and cell signal transduction.

Skalski JH, Kottom TJ, Limper AH.

FEMS Yeast Res. 2015 Sep;15(6). pii: fov046. doi: 10.1093/femsyr/fov046. Epub 2015 Jun 12. Review.

PMID:
26071598
6.

Evidence for Proinflammatory β-1,6 Glucans in the Pneumocystis carinii Cell Wall.

Kottom TJ, Hebrink DM, Jenson PE, Gudmundsson G, Limper AH.

Infect Immun. 2015 Jul;83(7):2816-26. doi: 10.1128/IAI.00196-15. Epub 2015 Apr 27.

7.

The Pneumocystis Ace2 transcription factor regulates cell wall-remodeling genes and organism virulence.

Kottom TJ, Limper AH.

J Biol Chem. 2013 Aug 16;288(33):23893-902. doi: 10.1074/jbc.M113.471243. Epub 2013 Jun 25.

8.

Characterization of the Pneumocystis carinii histone acetyltransferase chaperone proteins PcAsf1 and PcVps75.

Pupaibool J, Kottom TJ, Bouchonville K, Limper AH.

Infect Immun. 2013 Jun;81(6):2268-75. doi: 10.1128/IAI.01173-12. Epub 2013 Apr 8.

9.

Chitinases in Pneumocystis carinii pneumonia.

Villegas LR, Kottom TJ, Limper AH.

Med Microbiol Immunol. 2012 Aug;201(3):337-48. doi: 10.1007/s00430-012-0239-0. Epub 2012 Apr 26.

10.

Glycosphingolipids mediate pneumocystis cell wall β-glucan activation of the IL-23/IL-17 axis in human dendritic cells.

Carmona EM, Kottom TJ, Hebrink DM, Moua T, Singh RD, Pagano RE, Limper AH.

Am J Respir Cell Mol Biol. 2012 Jul;47(1):50-9. doi: 10.1165/rcmb.2011-0159OC. Epub 2012 Feb 16.

11.
14.

ERBB receptor activation is required for profibrotic responses to transforming growth factor beta.

Andrianifahanana M, Wilkes MC, Repellin CE, Edens M, Kottom TJ, Rahimi RA, Leof EB.

Cancer Res. 2010 Oct 1;70(19):7421-30. doi: 10.1158/0008-5472.CAN-10-0232. Epub 2010 Sep 14.

15.

Pneumocystis carinii expresses an active Rtt109 histone acetyltransferase.

Kottom TJ, Han J, Zhang Z, Limper AH.

Am J Respir Cell Mol Biol. 2011 Jun;44(6):768-76. doi: 10.1165/rcmb.2009-0443OC. Epub 2010 Jul 23.

16.

Cigarette smoke promotes dendritic cell accumulation in COPD; a Lung Tissue Research Consortium study.

Vassallo R, Walters PR, Lamont J, Kottom TJ, Yi ES, Limper AH.

Respir Res. 2010 Apr 26;11:45. doi: 10.1186/1465-9921-11-45.

17.

Characterization of the PcCdc42 small G protein from Pneumocystis carinii, which interacts with the PcSte20 life cycle regulatory kinase.

Krajicek BJ, Kottom TJ, Villegas L, Limper AH.

Am J Physiol Lung Cell Mol Physiol. 2010 Feb;298(2):L252-60. doi: 10.1152/ajplung.00191.2009. Epub 2009 Nov 13.

18.

Characterization of PCEng2, a {beta}-1,3-endoglucanase homolog in Pneumocystis carinii with activity in cell wall regulation.

Villegas LR, Kottom TJ, Limper AH.

Am J Respir Cell Mol Biol. 2010 Aug;43(2):192-200. doi: 10.1165/rcmb.2009-0131OC. Epub 2009 Sep 25.

19.

Characterization of a novel ADAM protease expressed by Pneumocystis carinii.

Kennedy CC, Kottom TJ, Limper AH.

Infect Immun. 2009 Aug;77(8):3328-36. doi: 10.1128/IAI.01383-08. Epub 2009 May 18.

20.

The Pneumocystis meiotic PCRan1p kinase exhibits unique temperature-regulated activity.

Burgess JW, Kottom TJ, Villegas LR, Lamont JD, Baden EM, Ramirez-Alvarado M, Limper AH.

Am J Respir Cell Mol Biol. 2009 Dec;41(6):714-21. doi: 10.1165/rcmb.2008-0098OC. Epub 2009 Mar 13.

21.

Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta.

Rahimi RA, Andrianifahanana M, Wilkes MC, Edens M, Kottom TJ, Blenis J, Leof EB.

Cancer Res. 2009 Jan 1;69(1):84-93. doi: 10.1158/0008-5472.CAN-08-2146.

22.

Pneumocystis PCINT1, a molecule with integrin-like features that mediates organism adhesion to fibronectin.

Kottom TJ, Kennedy CC, Limper AH.

Mol Microbiol. 2008 Feb;67(4):747-61. doi: 10.1111/j.1365-2958.2007.06093.x. Epub 2007 Dec 19.

23.

Pneumocystis carinii exhibits a conserved meiotic control pathway.

Burgess JW, Kottom TJ, Limper AH.

Infect Immun. 2008 Jan;76(1):417-25. Epub 2007 Nov 5.

24.

Pneumocystis cell wall beta-glucans induce dendritic cell costimulatory molecule expression and inflammatory activation through a Fas-Fas ligand mechanism.

Carmona EM, Vassallo R, Vuk-Pavlovic Z, Standing JE, Kottom TJ, Limper AH.

J Immunol. 2006 Jul 1;177(1):459-67.

25.

Pneumocystis melanins confer enhanced organism viability.

Icenhour CR, Kottom TJ, Limper AH.

Eukaryot Cell. 2006 Jun;5(6):916-23.

26.

Pneumocystis cell wall beta-glucans stimulate alveolar epithelial cell chemokine generation through nuclear factor-kappaB-dependent mechanisms.

Evans SE, Hahn PY, McCann F, Kottom TJ, Pavlovic' ZV, Limper AH.

Am J Respir Cell Mol Biol. 2005 Jun;32(6):490-7. Epub 2005 Mar 3.

27.

Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis.

Daniels CE, Wilkes MC, Edens M, Kottom TJ, Murphy SJ, Limper AH, Leof EB.

J Clin Invest. 2004 Nov;114(9):1308-16.

29.

Pneumocystis carinii BCK1 complements the Saccharomyces cerevisiae cell wall integrity pathway.

Vohra PK, Kottom TJ, Limper AH, Thomas CF Jr.

J Eukaryot Microbiol. 2003;50 Suppl:676-7. No abstract available.

PMID:
14736215
30.

Microarray analysis of lung epithelial responses to Pneumocystis carinii.

Kottom TJ, Limper AH.

J Eukaryot Microbiol. 2003;50 Suppl:629. No abstract available.

PMID:
14736190
31.

Melanin-like pigments in Pneumocystis carinii.

Icenhour CR, Kottom TJ, Limper AH.

J Eukaryot Microbiol. 2003;50 Suppl:621. No abstract available.

PMID:
14736186
33.

Evidence for a melanin cell wall component in Pneumocystis carinii.

Icenhour CR, Kottom TJ, Limper AH.

Infect Immun. 2003 Sep;71(9):5360-3.

34.

Pneumocystis carinii STE11, an HMG-box protein, is phosphorylated by the mitogen activated protein kinase PCM.

Vohra PK, Puri V, Kottom TJ, Limper AH, Thomas CF Jr.

Gene. 2003 Jul 17;312:173-9.

PMID:
12909353
35.

Pneumocystis carinii BCK1 functions in a mitogen-activated protein kinase cascade regulating fungal cell-wall assembly.

Thomas CF Jr, Vohra PK, Park JG, Puri V, Limper AH, Kottom TJ.

FEBS Lett. 2003 Jul 31;548(1-3):59-68.

36.

Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii.

Morales IJ, Vohra PK, Puri V, Kottom TJ, Limper AH, Thomas CF Jr.

Am J Respir Cell Mol Biol. 2003 Aug;29(2):232-8. Epub 2003 Feb 26.

PMID:
12606318
37.

Pneumocystis carinii cell wall beta-glucan induces release of macrophage inflammatory protein-2 from alveolar epithelial cells via a lactosylceramide-mediated mechanism.

Hahn PY, Evans SE, Kottom TJ, Standing JE, Pagano RE, Limper AH.

J Biol Chem. 2003 Jan 17;278(3):2043-50. Epub 2002 Nov 4.

38.

A gene complex mediating cyst wall assembly and integrity in Pneumocystis carinii.

Kottom TJ, Limper AH.

J Eukaryot Microbiol. 2001;Suppl:133S. No abstract available.

PMID:
11906025
39.
40.
41.

Vitronectin and fibronectin function as glucan binding proteins augmenting macrophage responses to Pneumocystis carinii.

Vassallo R, Kottom TJ, Standing JE, Limper AH.

Am J Respir Cell Mol Biol. 2001 Aug;25(2):203-11.

PMID:
11509330
42.
43.

Pneumocystis carinii uses a functional cdc13 B-type cyclin complex during its life cycle.

Kottom TJ, Thomas CF Jr, Mubarak KK, Leof EB, Limper AH.

Am J Respir Cell Mol Biol. 2000 Jun;22(6):722-31.

PMID:
10837370
44.

Assembly of cell wall glucans by Pneumocystis carinii: characterization of the Gsc-1 subunit mediating beta-glucan synthesis.

Kottom TJ, Limper AH.

J Eukaryot Microbiol. 1999 Sep-Oct;46(5):131S. No abstract available.

PMID:
10519285
45.

Characterization of a mitogen-activated protein kinase from Pneumocystis carinii.

Thomas CF Jr, Kottom TJ, Leof EB, Limper AH.

Am J Physiol. 1998 Jul;275(1 Pt 1):L193-9.

PMID:
9688951
46.

Characterization of the Pneumocystis carinii cyclin-dependent kinase life cycle regulatory system.

Limper AH, Thomas CF Jr, Mubarak KK, Gustafson MP, Kottom TJ, Leof EB.

J Eukaryot Microbiol. 1997 Nov-Dec;44(6):32S. No abstract available.

PMID:
9508420
47.

Further characterization of a complement-sensitive mutant of a virulent avian Escherichia coli isolate.

Kottom TJ, Nolan LK, Robinson M, Brown J, Gustad T, Horne SM, Giddings CW.

Avian Dis. 1997 Oct-Dec;41(4):817-23.

PMID:
9454914
48.

Decreased intracellular survival of an fkpA mutant of Salmonella typhimurium Copenhagen.

Horne SM, Kottom TJ, Nolan LK, Young KD.

Infect Immun. 1997 Feb;65(2):806-10.

49.

Invasion of Caco-2 cells by Salmonella typhimurium (Copenhagen) isolates from healthy and sick chickens.

Kottom TJ, Nolan LK, Brown J.

Avian Dis. 1995 Oct-Dec;39(4):867-72.

PMID:
8719222

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