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Items: 1 to 50 of 117

1.

Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus.

Ilca SL, Sun X, El Omari K, Kotecha A, de Haas F, DiMaio F, Grimes JM, Stuart DI, Poranen MM, Huiskonen JT.

Nature. 2019 Jun;570(7760):252-256. doi: 10.1038/s41586-019-1229-9. Epub 2019 May 29.

PMID:
31142835
2.

The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.

Ren J, Nettleship JE, Harris G, Mwangi W, Rhaman N, Grant C, Kotecha A, Fry E, Charleston B, Stuart DI, Hammond J, Owens RJ.

Mol Immunol. 2019 May 14;112:123-130. doi: 10.1016/j.molimm.2019.04.026. [Epub ahead of print]

3.

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.

El Omari K, Li S, Kotecha A, Walter TS, Bignon EA, Harlos K, Somerharju P, De Haas F, Clare DK, Molin M, Hurtado F, Li M, Grimes JM, Bamford DH, Tischler ND, Huiskonen JT, Stuart DI, Roine E.

Nat Commun. 2019 Feb 19;10(1):846. doi: 10.1038/s41467-019-08728-7.

4.

Author Correction: GABAA receptor signalling mechanisms revealed by structural pharmacology.

Masiulis S, Desai R, Uchański T, Martin IS, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR.

Nature. 2019 Feb;566(7744):E8. doi: 10.1038/s41586-019-0929-5.

PMID:
30733619
5.

Complete resolution of erythrodermic psoriasis with first-line apremilast monotherapy.

Krishnamoorthy G, Kotecha A, Pimentel J.

BMJ Case Rep. 2019 Jan 31;12(1). pii: e226959. doi: 10.1136/bcr-2018-226959.

PMID:
30709830
6.

GABAA receptor signalling mechanisms revealed by structural pharmacology.

Masiulis S, Desai R, Uchański T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR.

Nature. 2019 Jan;565(7740):454-459. doi: 10.1038/s41586-018-0832-5. Epub 2019 Jan 2. Erratum in: Nature. 2019 Feb 7;:.

PMID:
30602790
7.

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.

Zhou D, Zhao Y, Kotecha A, Fry EE, Kelly JT, Wang X, Rao Z, Rowlands DJ, Ren J, Stuart DI.

Nat Microbiol. 2019 Mar;4(3):414-419. doi: 10.1038/s41564-018-0319-z. Epub 2018 Dec 10.

8.

Development and performance of a novel vasopressor-driven mortality prediction model in septic shock.

Vallabhajosyula S, Jentzer JC, Kotecha AA, Murphree DH Jr, Barreto EF, Khanna AK, Iyer VN.

Ann Intensive Care. 2018 Nov 22;8(1):112. doi: 10.1186/s13613-018-0459-6.

9.

Chimeric O1K foot-and-mouth disease virus with SAT2 outer capsid as an FMD vaccine candidate.

Kotecha A, Perez-Martin E, Harvey Y, Zhang F, Ilca SL, Fry EE, Jackson B, Maree F, Scott K, Hecksel CW, Harmsen MM, Mioulet V, Wood B, Juleff N, Stuart DI, Charleston B, Seago J.

Sci Rep. 2018 Sep 12;8(1):13654. doi: 10.1038/s41598-018-31856-x.

10.

Machining protein microcrystals for structure determination by electron diffraction.

Duyvesteyn HME, Kotecha A, Ginn HM, Hecksel CW, Beale EV, de Haas F, Evans G, Zhang P, Chiu W, Stuart DI.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9569-9573. doi: 10.1073/pnas.1809978115. Epub 2018 Aug 31.

11.

Generation and characterisation of recombinant FMDV antibodies: Applications for advancing diagnostic and laboratory assays.

Shimmon G, Kotecha A, Ren J, Asfor AS, Newman J, Berryman S, Cottam EM, Gold S, Tuthill TJ, King DP, Brocchi E, King AMQ, Owens R, Fry EE, Stuart DI, Burman A, Jackson T.

PLoS One. 2018 Aug 16;13(8):e0201853. doi: 10.1371/journal.pone.0201853. eCollection 2018.

12.

Olfactory Dysfunction as a Global Biomarker for Sniffing out Alzheimer's Disease: A Meta-Analysis.

Kotecha AM, Corrêa ADC, Fisher KM, Rushworth JV.

Biosensors (Basel). 2018 Apr 13;8(2). pii: E41. doi: 10.3390/bios8020041.

13.

Clinical Outcomes of Weight-Based Norepinephrine Dosing in Underweight and Morbidly Obese Patients: A Propensity-Matched Analysis.

Kotecha AA, Vallabhajosyula S, Apala DR, Frazee E, Iyer VN.

J Intensive Care Med. 2018 Jan 1:885066618768180. doi: 10.1177/0885066618768180. [Epub ahead of print]

PMID:
29628015
14.

Impact of Age on Outcomes in Hospitalized Patients with Hereditary Hemorrhagic Telangiectasia.

Iyer VN, Brinjikji W, Apala D, Pannu BS, Kotecha A, Leise MD, Kamath PS, Misra S, Lanzino G, Krowka MJ, Wood CP, Swanson KL.

Adv Hematol. 2018 Feb 11;2018:4798425. doi: 10.1155/2018/4798425. eCollection 2018.

15.

Analysing barriers to service improvement using a multi-level theory of innovation: the case of glaucoma outpatient clinics.

Turner S, Vasilakis C, Utley M, Foster P, Kotecha A, Fulop NJ.

Sociol Health Illn. 2018 May;40(4):654-669. doi: 10.1111/1467-9566.12670. Epub 2018 Feb 13.

PMID:
29441595
16.

Intravenous Bevacizumab for Refractory Hereditary Hemorrhagic Telangiectasia-Related Epistaxis and Gastrointestinal Bleeding.

Iyer VN, Apala DR, Pannu BS, Kotecha A, Brinjikji W, Leise MD, Kamath PS, Misra S, Begna KH, Cartin-Ceba R, DuBrock HM, Krowka MJ, O'Brien EK, Pruthi RK, Schroeder DR, Swanson KL.

Mayo Clin Proc. 2018 Feb;93(2):155-166. doi: 10.1016/j.mayocp.2017.11.013. Epub 2018 Jan 24. Erratum in: Mayo Clin Proc. 2018 Mar;93(3):396.

PMID:
29395350
17.

Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy.

Zeltins A, West J, Zabel F, El Turabi A, Balke I, Haas S, Maudrich M, Storni F, Engeroff P, Jennings GT, Kotecha A, Stuart DI, Foerster J, Bachmann MF.

NPJ Vaccines. 2017 Oct 23;2:30. doi: 10.1038/s41541-017-0030-8. eCollection 2017.

18.

Example of monitoring measurements in a virtual eye clinic using 'big data'.

Jones L, Bryan SR, Miranda MA, Crabb DP, Kotecha A.

Br J Ophthalmol. 2018 Jul;102(7):911-915. doi: 10.1136/bjophthalmol-2017-310440. Epub 2017 Oct 26.

PMID:
29074497
19.

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation.

Malik N, Kotecha A, Gold S, Asfor A, Ren J, Huiskonen JT, Tuthill TJ, Fry EE, Stuart DI.

PLoS Pathog. 2017 Sep 22;13(9):e1006607. doi: 10.1371/journal.ppat.1006607. eCollection 2017 Sep.

20.

Saddle vs Nonsaddle Pulmonary Embolism: Clinical Presentation, Hemodynamics, Management, and Outcomes.

Alkinj B, Pannu BS, Apala DR, Kotecha A, Kashyap R, Iyer VN.

Mayo Clin Proc. 2017 Oct;92(10):1511-1518. doi: 10.1016/j.mayocp.2017.07.014. Epub 2017 Sep 8.

PMID:
28890217
21.

Cardiorenal syndrome in sepsis: A narrative review.

Kotecha A, Vallabhajosyula S, Coville HH, Kashani K.

J Crit Care. 2018 Feb;43:122-127. doi: 10.1016/j.jcrc.2017.08.044. Epub 2017 Sep 1. Review.

PMID:
28881261
22.

Bone metastases of the hand.

Morris G, Evans S, Stevenson J, Kotecha A, Parry M, Jeys L, Grimer R.

Ann R Coll Surg Engl. 2017 Sep;99(7):563-567. doi: 10.1308/rcsann.2017.0096.

23.

Developing standards for the development of glaucoma virtual clinics using a modified Delphi approach.

Kotecha A, Longstaff S, Azuara-Blanco A, Kirwan JF, Morgan JE, Spencer AF, Foster PJ.

Br J Ophthalmol. 2018 Apr;102(4):531-534. doi: 10.1136/bjophthalmol-2017-310504. Epub 2017 Aug 18.

PMID:
28821554
24.

Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine.

Marsian J, Fox H, Bahar MW, Kotecha A, Fry EE, Stuart DI, Macadam AJ, Rowlands DJ, Lomonossoff GP.

Nat Commun. 2017 Aug 15;8(1):245. doi: 10.1038/s41467-017-00090-w.

25.

High-speed fixed-target serial virus crystallography.

Roedig P, Ginn HM, Pakendorf T, Sutton G, Harlos K, Walter TS, Meyer J, Fischer P, Duman R, Vartiainen I, Reime B, Warmer M, Brewster AS, Young ID, Michels-Clark T, Sauter NK, Kotecha A, Kelly J, Rowlands DJ, Sikorsky M, Nelson S, Damiani DS, Alonso-Mori R, Ren J, Fry EE, David C, Stuart DI, Wagner A, Meents A.

Nat Methods. 2017 Aug;14(8):805-810. doi: 10.1038/nmeth.4335. Epub 2017 Jun 19.

26.

Prevalence of Clostridium difficile infection in acute care hospitals, long-term care facilities, and outpatient clinics: Is Clostridium difficile infection underdiagnosed in long-term care facility patients?

Krishna A, Pervaiz A, Lephart P, Tarabishy N, Varakantam S, Kotecha A, Awali RA, Kaye KS, Chopra T.

Am J Infect Control. 2017 Oct 1;45(10):1157-1159. doi: 10.1016/j.ajic.2017.04.288.

PMID:
28602273
27.

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus.

Kotecha A, Wang Q, Dong X, Ilca SL, Ondiviela M, Zihe R, Seago J, Charleston B, Fry EE, Abrescia NGA, Springer TA, Huiskonen JT, Stuart DI.

Nat Commun. 2017 May 23;8:15408. doi: 10.1038/ncomms15408.

28.

CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome.

Zhou JC, Janska A, Goswami P, Renault L, Abid Ali F, Kotecha A, Diffley JFX, Costa A.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4141-4146. doi: 10.1073/pnas.1700530114. Epub 2017 Apr 3.

29.

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability.

Scott KA, Kotecha A, Seago J, Ren J, Fry EE, Stuart DI, Charleston B, Maree FF.

J Virol. 2017 Apr 28;91(10). pii: e02312-16. doi: 10.1128/JVI.02312-16. Print 2017 May 15.

30.

Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.

Sun Z, El Omari K, Sun X, Ilca SL, Kotecha A, Stuart DI, Poranen MM, Huiskonen JT.

Nat Commun. 2017 Mar 13;8:14814. doi: 10.1038/ncomms14814.

31.

The B Cell Response to Foot-and-Mouth Disease Virus in Cattle following Sequential Vaccination with Multiple Serotypes.

Grant CFJ, Carr BV, Kotecha A, van den Born E, Stuart DI, Hammond JA, Charleston B.

J Virol. 2017 Apr 13;91(9). pii: e02157-16. doi: 10.1128/JVI.02157-16. Print 2017 May 1.

32.

A technician-delivered 'virtual clinic' for triaging low-risk glaucoma referrals.

Kotecha A, Brookes J, Foster PJ.

Eye (Lond). 2017 Jun;31(6):899-905. doi: 10.1038/eye.2017.9. Epub 2017 Feb 17.

33.

Quality of Life in the Tube Versus Trabeculectomy Study.

Kotecha A, Feuer WJ, Barton K, Gedde SJ; Tube Versus Trabeculectomy Study Group.

Am J Ophthalmol. 2017 Apr;176:228-235. doi: 10.1016/j.ajo.2017.01.019. Epub 2017 Feb 1.

PMID:
28161049
34.

Multifocal micronodular pneumocyte hyperplasia (MMPH) in a patient with tuberous sclerosis-evidence for long term stability.

Pannu BS, Apala DR, Kotecha A, Boland JM, Iyer VN.

Respir Med Case Rep. 2017 Jan 18;20:113-115. doi: 10.1016/j.rmcr.2017.01.010. eCollection 2017.

35.

Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site.

Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Kotecha A, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):770-775. doi: 10.1073/pnas.1616502114. Epub 2017 Jan 10.

36.

A supramolecular assembly mediates lentiviral DNA integration.

Ballandras-Colas A, Maskell DP, Serrao E, Locke J, Swuec P, Jónsson SR, Kotecha A, Cook NJ, Pye VE, Taylor IA, Andrésdóttir V, Engelman AN, Costa A, Cherepanov P.

Science. 2017 Jan 6;355(6320):93-95. doi: 10.1126/science.aah7002.

37.

Megaprostheses in the management of trauma of the knee.

Evans S, Laugharne E, Kotecha A, Hadley L, Ramasamy A, Jeys L.

J Orthop. 2015 Dec 7;13(4):467-471. eCollection 2016 Dec.

38.

Structure of human Aichi virus and implications for receptor binding.

Zhu L, Wang X, Ren J, Kotecha A, Walter TS, Yuan S, Yamashita T, Tuthill TJ, Fry EE, Rao Z, Stuart DI.

Nat Microbiol. 2016 Sep 5;1(11):16150. doi: 10.1038/nmicrobiol.2016.150.

PMID:
27595320
39.

Virtual clinics in glaucoma care: face-to-face versus remote decision-making.

Clarke J, Puertas R, Kotecha A, Foster PJ, Barton K.

Br J Ophthalmol. 2017 Jul;101(7):892-895. doi: 10.1136/bjophthalmol-2016-308993. Epub 2016 Oct 11.

PMID:
27729310
40.

Standing Balance Stability and the Effects of Light Touch in Adults With Profound Loss of Vision-An Exploratory Study.

Kotecha A, Webster AR, Wright G, Michaelides M, Rubin GS.

Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):5053-5059. doi: 10.1167/iovs.16-19606.

PMID:
27661857
41.

Cytomegalovirus infection in autologous stem cell transplant recipients in the era of rituximab.

Jain T, John J, Kotecha A, Deol A, Saliminia T, Revankar S, Chandrasekar P.

Ann Hematol. 2016 Aug;95(8):1323-7. doi: 10.1007/s00277-016-2700-4. Epub 2016 May 25.

PMID:
27225264
42.

Patient satisfaction in the Peterborough community specialist optometrist in glaucoma shared-care scheme.

Roberts HW, Sood M, Sood S, Kotecha A, Ramirez-Florez S.

Eye (Lond). 2016 Aug;30(8):1149-50. doi: 10.1038/eye.2016.80. Epub 2016 Apr 22. No abstract available.

43.

Application of the thermofluor PaSTRy technique for improving foot-and-mouth disease virus vaccine formulation.

Kotecha A, Zhang F, Juleff N, Jackson T, Perez E, Stuart D, Fry E, Charleston B, Seago J.

J Gen Virol. 2016 Jul;97(7):1557-65. doi: 10.1099/jgv.0.000462. Epub 2016 Mar 22.

44.

Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate.

Abid Ali F, Renault L, Gannon J, Gahlon HL, Kotecha A, Zhou JC, Rueda D, Costa A.

Nat Commun. 2016 Feb 18;7:10708. doi: 10.1038/ncomms10708.

45.

Modified Technique of Tibial Tuberosity Transfer.

Pemmaraju G, Raad A, Kotecha A, Chugh S, Mughal E.

Arthrosc Tech. 2015 Aug 10;4(4):e349-52. doi: 10.1016/j.eats.2015.03.009. eCollection 2015 Aug.

46.

Qualitative investigation of patients' experience of a glaucoma virtual clinic in a specialist ophthalmic hospital in London, UK.

Kotecha A, Bonstein K, Cable R, Cammack J, Clipston J, Foster P.

BMJ Open. 2015 Dec 15;5(12):e009463. doi: 10.1136/bmjopen-2015-009463.

47.

Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes.

Ilca SL, Kotecha A, Sun X, Poranen MM, Stuart DI, Huiskonen JT.

Nat Commun. 2015 Nov 4;6:8843. doi: 10.1038/ncomms9843.

48.

Experiences with developing and implementing a virtual clinic for glaucoma care in an NHS setting.

Kotecha A, Baldwin A, Brookes J, Foster PJ.

Clin Ophthalmol. 2015 Oct 15;9:1915-23. doi: 10.2147/OPTH.S92409. eCollection 2015.

49.

Applanation tonometry: interobserver and prism agreement using the reusable Goldmann applanation prism and the Tonosafe disposable prism.

Ajtony C, Elkarmouty A, Barton K, Kotecha A.

Br J Ophthalmol. 2016 Jun;100(6):848-53. doi: 10.1136/bjophthalmol-2015-307240. Epub 2015 Oct 9.

PMID:
26453638
50.

Structure of Ljungan virus provides insight into genome packaging of this picornavirus.

Zhu L, Wang X, Ren J, Porta C, Wenham H, Ekström JO, Panjwani A, Knowles NJ, Kotecha A, Siebert CA, Lindberg AM, Fry EE, Rao Z, Tuthill TJ, Stuart DI.

Nat Commun. 2015 Oct 8;6:8316. doi: 10.1038/ncomms9316.

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