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Items: 1 to 50 of 87

1.

Editorial for "Ensemble Learning for Early-Response Prediction of Antidepressant Treatment in Major Depressive Disorder".

Srinath A, Romanos S, Lyne SB, Leporq B, Koskimäki J, Girard R.

J Magn Reson Imaging. 2020 Feb 8. doi: 10.1002/jmri.27081. [Epub ahead of print] No abstract available.

PMID:
32034809
2.

Symptomatic Brain Hemorrhages from Cavernous Angioma After Botulinum Toxin Injections, a Role of TLR/MEKK3 Mechanism? Case Report and Review of the Literature.

Koskimäki J, Zhang D, Carrión-Penagos J, Girard R, Piedad K, Polster SP, Lyne S, Stadnik A, Awad IA.

World Neurosurg. 2020 Jan 7;136:7-11. doi: 10.1016/j.wneu.2019.12.172. [Epub ahead of print]

PMID:
31917316
3.

Phantom validation of quantitative susceptibility and dynamic contrast-enhanced permeability MR sequences across instruments and sites.

Hobson N, Polster SP, Cao Y, Flemming K, Shu Y, Huston J, Gerrard CY, Selwyn R, Mabray M, Zafar A, Girard R, Carrión-Penagos J, Chen YF, Parrish T, Zhou XJ, Koenig JI, Shenkar R, Stadnik A, Koskimäki J, Dimov A, Turley D, Carroll T, Awad IA.

J Magn Reson Imaging. 2019 Sep 12. doi: 10.1002/jmri.26927. [Epub ahead of print]

PMID:
31515878
4.

A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.

McKerracher L, Shenkar R, Abbinanti M, Cao Y, Peiper A, Liao JK, Lightle R, Moore T, Hobson N, Gallione C, Ruschel J, Koskimäki J, Girard R, Rosen K, Marchuk DA, Awad IA.

Transl Stroke Res. 2019 Aug 24. doi: 10.1007/s12975-019-00725-8. [Epub ahead of print]

PMID:
31446620
5.

Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.

Koskimäki J, Zhang D, Li Y, Saadat L, Moore T, Lightle R, Polster SP, Carrión-Penagos J, Lyne SB, Zeineddine HA, Shi C, Shenkar R, Romanos S, Avner K, Srinath A, Shen L, Detter MR, Snellings D, Cao Y, Lopez-Ramirez MA, Fonseca G, Tang AT, Faber P, Andrade J, Ginsberg M, Kahn ML, Marchuk DA, Girard R, Awad IA.

Acta Neuropathol Commun. 2019 Aug 19;7(1):132. doi: 10.1186/s40478-019-0789-0.

6.

Biomarkers of cavernous angioma with symptomatic hemorrhage.

Lyne SB, Girard R, Koskimäki J, Zeineddine HA, Zhang D, Cao Y, Li Y, Stadnik A, Moore T, Lightle R, Shi C, Shenkar R, Carrión-Penagos J, Polster SP, Romanos S, Akers A, Lopez-Ramirez M, Whitehead KJ, Kahn ML, Ginsberg MH, Marchuk DA, Awad IA.

JCI Insight. 2019 Jun 20;4(12). pii: 128577. doi: 10.1172/jci.insight.128577. eCollection 2019 Jun 20.

7.

Corpse management of the invasive Argentine ant inhibits growth of pathogenic fungi.

Kesäniemi J, Koskimäki JJ, Jurvansuu J.

Sci Rep. 2019 May 20;9(1):7593. doi: 10.1038/s41598-019-44144-z.

8.

A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis.

Chapman EM, Lant B, Ohashi Y, Yu B, Schertzberg M, Go C, Dogra D, Koskimäki J, Girard R, Li Y, Fraser AG, Awad IA, Abdelilah-Seyfried S, Gingras AC, Derry WB.

Nat Commun. 2019 Apr 17;10(1):1791. doi: 10.1038/s41467-019-09829-z.

9.

Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure.

Awad IA, Polster SP, Carrión-Penagos J, Thompson RE, Cao Y, Stadnik A, Money PL, Fam MD, Koskimäki J, Girard R, Lane K, McBee N, Ziai W, Hao Y, Dodd R, Carlson AP, Camarata PJ, Caron JL, Harrigan MR, Gregson BA, Mendelow AD, Zuccarello M, Hanley DF; MISTIE III Trial Investigators.

Neurosurgery. 2019 Jun 1;84(6):1157-1168. doi: 10.1093/neuros/nyz077.

PMID:
30891610
10.

Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.

Shenkar R, Peiper A, Pardo H, Moore T, Lightle R, Girard R, Hobson N, Polster SP, Koskimäki J, Zhang D, Lyne SB, Cao Y, Chaudagar K, Saadat L, Gallione C, Pytel P, Liao JK, Marchuk D, Awad IA.

Stroke. 2019 Mar;50(3):738-744. doi: 10.1161/STROKEAHA.118.024058.

PMID:
30744543
11.

Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.

Koskimäki J, Girard R, Li Y, Saadat L, Zeineddine HA, Lightle R, Moore T, Lyne S, Avner K, Shenkar R, Cao Y, Shi C, Polster SP, Zhang D, Carrión-Penagos J, Romanos S, Fonseca G, Lopez-Ramirez MA, Chapman EM, Popiel E, Tang AT, Akers A, Faber P, Andrade J, Ginsberg M, Derry WB, Kahn ML, Marchuk DA, Awad IA.

JCI Insight. 2019 Feb 7;4(3). pii: 126167. doi: 10.1172/jci.insight.126167. [Epub ahead of print]

12.

Risk Factors for Recurrent Hematoma After Surgery for Acute Traumatic Subdural Hematoma.

Heino I, Frantzén J, Rinne J, Girard R, Cao Y, Sajanti A, Katila AJ, Posti JP, Takala RSK, Tenovuo O, Koskimäki J.

World Neurosurg. 2019 Jan 10. pii: S1878-8750(19)30023-3. doi: 10.1016/j.wneu.2018.12.155. [Epub ahead of print]

PMID:
30639489
13.

Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial.

Polster SP, Stadnik A, Akers AL, Cao Y, Christoforidis GA, Fam MD, Flemming KD, Girard R, Hobson N, Koenig JI, Koskimäki J, Lane K, Liao JK, Lee C, Lyne SB, McBee N, Morrison L, Piedad K, Shenkar R, Sorrentino M, Thompson RE, Whitehead KJ, Zeineddine HA, Hanley DF, Awad IA.

Neurosurgery. 2019 Dec 1;85(6):843-853. doi: 10.1093/neuros/nyy539.

PMID:
30476251
14.

Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.

Lopez-Ramirez MA, Pham A, Girard R, Wyseure T, Hale P, Yamashita A, Koskimäki J, Polster S, Saadat L, Romero IA, Esmon CT, Lagarrigue F, Awad IA, Mosnier LO, Ginsberg MH.

Blood. 2019 Jan 17;133(3):193-204. doi: 10.1182/blood-2018-06-856062. Epub 2018 Nov 15.

15.

Impact of lower urinary tract symptoms on mortality: a 21-year follow-up among middle-aged and elderly Finnish men.

Åkerla J, Pesonen JS, Pöyhönen A, Häkkinen J, Koskimäki J, Huhtala H, Tammela TLJ, Auvinen A.

Prostate Cancer Prostatic Dis. 2019 May;22(2):317-323. doi: 10.1038/s41391-018-0108-z. Epub 2018 Nov 8.

PMID:
30410016
16.

Severity and bother of lower urinary tract symptoms among men aged 30-80 years: Tampere Ageing Male Urological Study (TAMUS).

Pöyhönen A, Åkerla J, Häkkinen JT, Koskimäki J, Tammela TLJ, Auvinen A.

Scand J Urol. 2018 Aug;52(4):296-301. doi: 10.1080/21681805.2018.1505944. Epub 2018 Nov 1.

PMID:
30382800
17.

Atorvastatin Versus Placebo for Prostate Cancer Before Radical Prostatectomy-A Randomized, Double-blind, Placebo-controlled Clinical Trial.

Murtola TJ, Syvälä H, Tolonen T, Helminen M, Riikonen J, Koskimäki J, Pakarainen T, Kaipia A, Isotalo T, Kujala P, Tammela TLJ.

Eur Urol. 2018 Dec;74(6):697-701. doi: 10.1016/j.eururo.2018.06.037. Epub 2018 Jul 18.

PMID:
30031572
18.

Phenotypic characterization of murine models of cerebral cavernous malformations.

Zeineddine HA, Girard R, Saadat L, Shen L, Lightle R, Moore T, Cao Y, Hobson N, Shenkar R, Avner K, Chaudager K, Koskimäki J, Polster SP, Fam MD, Shi C, Lopez-Ramirez MA, Tang AT, Gallione C, Kahn ML, Ginsberg M, Marchuk DA, Awad IA.

Lab Invest. 2019 Mar;99(3):319-330. doi: 10.1038/s41374-018-0030-y. Epub 2018 Jun 26.

19.

Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth.

Girard R, Zeineddine HA, Koskimäki J, Fam MD, Cao Y, Shi C, Moore T, Lightle R, Stadnik A, Chaudagar K, Polster S, Shenkar R, Duggan R, Leclerc D, Whitehead KJ, Li DY, Awad IA.

Circ Res. 2018 Jun 8;122(12):1716-1721. doi: 10.1161/CIRCRESAHA.118.312680. Epub 2018 May 2.

20.

Trial Readiness in Cavernous Angiomas With Symptomatic Hemorrhage (CASH).

Polster SP, Cao Y, Carroll T, Flemming K, Girard R, Hanley D, Hobson N, Kim H, Koenig J, Koskimäki J, Lane K, Majersik JJ, McBee N, Morrison L, Shenkar R, Stadnik A, Thompson RE, Zabramski J, Zeineddine HA, Awad IA.

Neurosurgery. 2019 Apr 1;84(4):954-964. doi: 10.1093/neuros/nyy108.

PMID:
29660039
21.

Different endophyte communities colonize buds of sprouts compared with mature trees of mountain birch recovered from moth herbivory.

Koivusaari P, Pohjanen J, Wäli PR, Ahonen SHK, Saravesi K, Markkola AM, Haapala K, Suokas M, Koskimäki JJ, Tejesvi MV, Pirttilä AM.

Tree Physiol. 2018 Sep 1;38(9):1437-1444. doi: 10.1093/treephys/tpy012.

PMID:
29481688
22.

Population-level and Individual-level Bother of Lower Urinary Tract Symptoms Among 30- to 80-year-old Men.

Pöyhönen A, Auvinen A, Häkkinen JT, Koskimäki J, Tammela TL.

Urology. 2016 Sep;95:164-70. doi: 10.1016/j.urology.2016.06.023. Epub 2016 Jun 24.

PMID:
27349526
23.

Methyl-esterified 3-hydroxybutyrate oligomers protect bacteria from hydroxyl radicals.

Koskimäki JJ, Kajula M, Hokkanen J, Ihantola EL, Kim JH, Hautajärvi H, Hankala E, Suokas M, Pohjanen J, Podolich O, Kozyrovska N, Turpeinen A, Pääkkönen M, Mattila S, Campbell BC, Pirttilä AM.

Nat Chem Biol. 2016 May;12(5):332-8. doi: 10.1038/nchembio.2043. Epub 2016 Mar 14.

PMID:
26974813
24.

Initiation of robot-assisted radical prostatectomies in Finland: Impact on centralization and quality of care.

Riikonen J, Kaipia A, Petas A, Horte A, Koskimäki J, Kähkönen E, Boström PJ, Paananen I, Kuisma J, Santti H, Matikainen M, Rannikko A.

Scand J Urol. 2016 Jun;50(3):149-54. doi: 10.3109/21681805.2016.1142471. Epub 2016 Feb 16.

PMID:
26881411
25.

The intracellular Scots pine shoot symbiont Methylobacterium extorquens DSM13060 aggregates around the host nucleus and encodes eukaryote-like proteins.

Koskimäki JJ, Pirttilä AM, Ihantola EL, Halonen O, Frank AC.

mBio. 2015 Mar 24;6(2). pii: e00039-15. doi: 10.1128/mBio.00039-15.

26.

Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model.

Koskimäki J, Tarkia M, Ahtola-Sätilä T, Saloranta L, Simola O, Forsback AP, Laakso A, Frantzén J.

Biomed Res Int. 2015;2015:715752. doi: 10.1155/2015/715752. Epub 2015 Jan 22.

27.

Absorption, elimination and cerebrospinal fluid concentrations of nimodipine in healthy beagle dogs receiving human intravenous and oral formulation.

Koskimäki J, Tarkia M, Ahtola-Sätilä T, Saloranta L, Laakso A, Frantzén J.

Eur J Drug Metab Pharmacokinet. 2016 Jun;41(3):295-300. doi: 10.1007/s13318-015-0258-5. Epub 2015 Feb 5.

PMID:
25652785
28.

Inhibition of breast cancer growth and metastasis by a biomimetic peptide.

Lee E, Lee SJ, Koskimaki JE, Han Z, Pandey NB, Popel AS.

Sci Rep. 2014 Nov 20;4:7139. doi: 10.1038/srep07139.

29.

A biomimetic collagen derived peptide exhibits anti-angiogenic activity in triple negative breast cancer.

Rosca EV, Penet MF, Mori N, Koskimaki JE, Lee E, Pandey NB, Bhujwalla ZM, Popel AS.

PLoS One. 2014 Nov 10;9(11):e111901. doi: 10.1371/journal.pone.0111901. eCollection 2014.

30.

Nimodipine activates TrkB neurotrophin receptors and induces neuroplastic and neuroprotective signaling events in the mouse hippocampus and prefrontal cortex.

Koskimäki J, Matsui N, Umemori J, Rantamäki T, Castrén E.

Cell Mol Neurobiol. 2015 Mar;35(2):189-96. doi: 10.1007/s10571-014-0110-5. Epub 2014 Sep 10.

PMID:
25204460
31.

Interaction with ectomycorrhizal fungi and endophytic Methylobacterium affects nutrient uptake and growth of pine seedlings in vitro.

Pohjanen J, Koskimäki JJ, Sutela S, Ardanov P, Suorsa M, Niemi K, Sarjala T, Häggman H, Pirttilä AM.

Tree Physiol. 2014 Sep;34(9):993-1005. doi: 10.1093/treephys/tpu062. Epub 2014 Aug 21.

PMID:
25149086
32.

Localization of strawberry (Fragaria x ananassa) and Methylobacterium extorquens genes of strawberry flavor biosynthesis in strawberry tissue by in situ hybridization.

Nasopoulou C, Pohjanen J, Koskimäki JJ, Zabetakis I, Pirttilä AM.

J Plant Physiol. 2014 Aug 15;171(13):1099-105. doi: 10.1016/j.jplph.2014.03.018. Epub 2014 May 2.

PMID:
24973582
33.

Detection of prostate cancer by an electronic nose: a proof of principle study.

Roine A, Veskimäe E, Tuokko A, Kumpulainen P, Koskimäki J, Keinänen TA, Häkkinen MR, Vepsäläinen J, Paavonen T, Lekkala J, Lehtimäki T, Tammela TL, Oksala NK.

J Urol. 2014 Jul;192(1):230-4. doi: 10.1016/j.juro.2014.01.113. Epub 2014 Feb 25.

PMID:
24582536
34.

Outcomes of medical and surgical treatment for lower urinary tract symptoms (benign prostatic obstruction)--a population-based cohort study.

Pöyhönen A, Auvinen A, Häkkinen JT, Koskimäki J, Hakama M, Tammela TL.

Int J Clin Pract. 2014 Mar;68(3):349-55. doi: 10.1111/ijcp.12318. Epub 2013 Dec 22.

PMID:
24372641
35.

Natural course of lower urinary tract symptoms in men not requiring treatment--a 5-year longitudinal population-based study.

Pöyhönen A, Häkkinen JT, Koskimäki J, Tammela TL, Auvinen A.

Urology. 2014 Feb;83(2):411-5. doi: 10.1016/j.urology.2013.10.003. Epub 2013 Nov 15.

PMID:
24246327
36.

Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide.

Shmueli RB, Ohnaka M, Miki A, Pandey NB, Lima e Silva R, Koskimaki JE, Kim J, Popel AS, Campochiaro PA, Green JJ.

Biomaterials. 2013 Oct;34(30):7544-51. doi: 10.1016/j.biomaterials.2013.06.044. Epub 2013 Jul 10.

37.

Side-fenestrated catheter decreases leakage at the urethrovesical anastomosis after robot-assisted laparoscopic radical prostatectomy.

Riikonen J, Kaipia A, Matikainen M, Koskimäki J, Kylmälä T, Tammela TL.

Scand J Urol. 2014 Feb;48(1):21-6. doi: 10.3109/21681805.2013.777365. Epub 2013 Mar 15.

PMID:
23495792
39.

Wing shape and its influence on the outcome of territorial contests in the damselfly Calopteryx virgo.

Bots J, Breuker CJ, Kaunisto KM, Koskimäki J, Gossum HV, Suhonen J.

J Insect Sci. 2012;12:96. doi: 10.1673/031.012.9601.

40.

Empirical evaluation of grouping of lower urinary tract symptoms: principal component analysis of Tampere Ageing Male Urological Study data.

Pöyhönen A, Häkkinen JT, Koskimäki J, Hakama M, Tammela TL, Auvinen A.

BJU Int. 2013 Mar;111(3):467-73. doi: 10.1111/j.1464-410X.2012.11593.x. Epub 2012 Oct 26.

41.

Synergy between a collagen IV mimetic peptide and a somatotropin-domain derived peptide as angiogenesis and lymphangiogenesis inhibitors.

Koskimaki JE, Lee E, Chen W, Rivera CG, Rosca EV, Pandey NB, Popel AS.

Angiogenesis. 2013 Jan;16(1):159-70. doi: 10.1007/s10456-012-9308-7. Epub 2012 Sep 29.

42.

Detection of smell print differences between nonmalignant and malignant prostate cells with an electronic nose.

Roine A, Tolvanen M, Sipiläinen M, Kumpulainen P, Helenius MA, Lehtimäki T, Vepsäläinen J, Keinänen TA, Häkkinen MR, Koskimäki J, Veskimäe E, Tuokko A, Visakorpi T, Tammela TL, Sioris T, Paavonen T, Lekkala J, Helle H, Oksala NK.

Future Oncol. 2012 Sep;8(9):1157-65. doi: 10.2217/fon.12.93.

PMID:
23030490
43.

Prevalence and bother of postmicturition dribble in Finnish men aged 30-80 years: Tampere Ageing Male Urologic Study (TAMUS).

Pöyhönen A, Auvinen A, Koskimäki J, Hakama M, Tammela TL, Häkkinen JT.

Scand J Urol Nephrol. 2012 Dec;46(6):418-23. doi: 10.3109/00365599.2012.702786. Epub 2012 Jul 27.

PMID:
22835055
44.

Serpin-derived peptides are antiangiogenic and suppress breast tumor xenograft growth.

Koskimaki JE, Rosca EV, Rivera CG, Lee E, Chen W, Pandey NB, Popel AS.

Transl Oncol. 2012 Apr;5(2):92-7. Epub 2012 Apr 1.

45.

Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth.

Rosca EV, Lal B, Koskimaki JE, Popel AS, Laterra J.

Anticancer Drugs. 2012 Aug;23(7):706-12. doi: 10.1097/CAD.0b013e3283531041.

46.

Structure-activity relationship study of collagen-derived anti-angiogenic biomimetic peptides.

Rosca EV, Koskimaki JE, Pandey NB, Tamiz AP, Popel AS.

Chem Biol Drug Des. 2012 Jul;80(1):27-37. doi: 10.1111/j.1747-0285.2012.01376.x. Epub 2012 Apr 27.

47.

Prevalence of hesitancy in 30-80-year-old Finnish men: Tampere Ageing Male Urological Study (TAMUS).

Pöyhönen A, Häkkinen JT, Koskimäki J, Hakama M, Tammela TL, Auvinen A.

BJU Int. 2012 May;109(9):1360-4. doi: 10.1111/j.1464-410X.2011.10443.x. Epub 2011 Aug 24.

48.

Development of a biomimetic peptide derived from collagen IV with anti-angiogenic activity in breast cancer.

Rosca EV, Koskimaki JE, Pandey NB, Wolff AC, Popel AS.

Cancer Biol Ther. 2011 Nov 1;12(9):808-17. doi: 10.4161/cbt.12.9.17677. Epub 2011 Nov 1.

49.

Novel peptide-specific quantitative structure-activity relationship (QSAR) analysis applied to collagen IV peptides with antiangiogenic activity.

Rivera CG, Rosca EV, Pandey NB, Koskimaki JE, Bader JS, Popel AS.

J Med Chem. 2011 Oct 13;54(19):6492-500. doi: 10.1021/jm200114f. Epub 2011 Sep 13.

50.

Anti-angiogenic peptides for cancer therapeutics.

Rosca EV, Koskimaki JE, Rivera CG, Pandey NB, Tamiz AP, Popel AS.

Curr Pharm Biotechnol. 2011 Aug;12(8):1101-16. Review.

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